4OJM,1X8X,1Q11,2DLC,2YY5


Conserved Protein Domain Family
tRNA-synt_1b

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pfam00579: tRNA-synt_1b 
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tRNA synthetases class I (W and Y)
Statistics
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PSSM-Id: 306950
View PSSM: pfam00579
Aligned: 37 rows
Threshold Bit Score: 231.403
Threshold Setting Gi: 2501073
Created: 12-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4OJM_X  60 MR-TRRIGAYVGIDPTAPsLHVG-HLLPLMPLFWMYL-----EGYKAFTLIGGSTAKIGDPTgRLKSRDHLSSSDATMNM 132 Neurospora crassa OR74A
O84589   3 KK-----RVLTGDRPTGK-LHLGhWIGSIMNRLQLQNd----SRYDCFFIIADLHTLTTKTR-KEEILQIDNHIYDVLAD 71  Chlamydia trachomatis...
P00954   3 KP-----IVFSGAQPSGE-LTIGnYMGALRQWVNMQ------DDYHCIYCIVDQHAITVRQD----AQKLRKATLDTLAL 66  Escherichia coli K-12
Q5L1T6   1 -----mkTIFSGIQPSGV-ITLGnYIGALRQFVELQ------HEYNCYFCIVDQHAITVWQD----PRELRQNIRRLAAL 64  Geobacillus kaustophilus
Q49901   3 TA-TGFSRIFSGVQPTSDsLHLGnALGAITQWVALQYdh--pDEYEAFFCVVDLHAITIAQD----PETLWRRTLVTAAQ 75  Mycobacterium leprae TN
P73655   3 KP-----RILSGVQPTGN-LHLGnYLGAIRSWVEQQ------QHYDNFFCVVDLHAITVPHN----PQTLAQDTLTIAAL 66  Synechocystis sp. PCC...
P56396   3 KK-----RVFSGIQPTGQ-IHLGnYLGAIKHWVEMQ------DEYENLFCVVNSHAITLPID----PAFLKSQSYELVKL 66  Helicobacter pylori 2...
O42875   8 TSlLPHSRVVSGIQPTGI-PHIGnYLGSLKQWVQLQEeaartPFSKCFFFVADLHALTVPQD----PLKFRQARLDMLAA 82  Schizosaccharomyces p...
P04803  29 EAlHSNATVFSMIQPTGC-FHLGnYLGATRVWTDLCElk--qPGQELIFGVADLHAITVPKP---DGEMFRKFRHEAVAS 102 Saccharomyces cerevis...
P46579  26 TS-THPTIYFTGIQPTGI-PHLGnFFGSIEPWTELQNsv--dKNILMMLSVVDQHAISLGPL---PANELRQNTHQMTAS 98  Caenorhabditis elegans
4OJM_X 133 tkihyQLKKLWENvdtqmrargyeadwarkRGIVNNNHWWNKQPMLEVLRRVGHALRIGPMLSRDT-----VKNKMTQ-G 206 Neurospora crassa OR74A
O84589  72 -----WLSVGIDPe---------------kSAIYLQSAIPEIYELNLIFSMLTPLNHIMGIPSIKEm---aRNASLNEeS 128 Chlamydia trachomatis...
P00954  67 -----YLACGIDPe---------------kSTIFVQSHVPEHAQLGWALNCYTYFGELSRMTQFKD-------KSARYa- 118 Escherichia coli K-12
Q5L1T6  65 -----YLAVGIDPt---------------qATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQFKE-------KSAGKe- 116 Geobacillus kaustophilus
Q49901  76 -----YLALGIDPg---------------rAVVFVQSHVPAHTQLAWVLGCFTGFGQASRMTQFKD-------KALRQga 128 Mycobacterium leprae TN
P73655  67 -----YLACGIDLq---------------ySTIFVQSHVAAHSELAWLLNCVTPLNWLERMIQFKE-------KAVKQg- 118 Synechocystis sp. PCC...
P56396  67 -----LLACGIDPk---------------qSGLFIQSEVDEHPALAWLLNCQVSMGEMQRMTQFKD-------KSLKNp- 118 Helicobacter pylori 2...
O42875  83 -----LLAIGINPq---------------kSTLFFQSDVAQHSELAWLLACSTSMGQLNRMTQWKSklhlhDHDDLSFlD 142 Schizosaccharomyces p...
P04803 103 -----ILAVGVDPe---------------kASVIYQSAIPQHSELHWLLSTLASMGLLNRMTQWKS------KSNIKQsT 156 Saccharomyces cerevis...
P46579  99 -----LIACGVDPn---------------rTLLFRQSDVPQIAQISWILGSLQTTSKLARLPQYKE-----KKERFKK-G 152 Caenorhabditis elegans
4OJM_X 207 d-----------GVSFAEFTYPIMQGWDWFELFYQqgvqMQIGGSDQYGNIISGLEVVKAARESepdpqerkyvtpktal 275 Neurospora crassa OR74A
O84589 129 l-------------sHGLIGYPVLQSADILLAKAH----LVPVGKDNEAHVELTRDIAKTFNRLyge-----------vf 180 Chlamydia trachomatis...
P00954 119 -----------eNINAGLFDYPVLMAADILLYQTN----LVPVGEDQKQHLELSRDIAQRFNALyge-----------if 172 Escherichia coli K-12
Q5L1T6 117 ------------AVSAGLLTYPPLMAADILLYNTD----IVPVGEDQKQHIELTRDLAERFNKRyge-----------lf 169 Geobacillus kaustophilus
Q49901 129 -----------dSTTVGLFTYPVLQAADVLAYDTD----LVPVGEDQRQHLELARDLAQRFNSRfpd-----------tf 182 Mycobacterium leprae TN
P73655 119 -----------eNVSVGLLDYPVLMAADILLYDAD----KVPVGEDQKQHLELTRDIVIRINDKfgred-------apvl 176 Synechocystis sp. PCC...
P56396 119 -----------kSVNVGLFNYPILMASDILLYQSD----LVPVGEDQKQHLELTRNIAEKFNRDfgn-----------cf 172 Helicobacter pylori 2...
O42875 143 asat-----sstRFNLGLFSYPVLQAADILLYGAT----HIPVGKDQSQHVELTRSIARSFNSSykek----------il 203 Schizosaccharomyces p...
P04803 157 ngdylvndsdvgKVRLGLFSYPVLQAADILLYKST----HVPVGDDQSQHLELTRHLAEKFNKMykkn----------ff 222 Saccharomyces cerevis...
P46579 153 ------------DIPVGLLTYPLLQAADVLTFKAT----TVPVGEDQSQHLNLLGGLAYAFNKTyete----------if 206 Caenorhabditis elegans
4OJM_X 276 dECVGFTVP----LLTDSSGA-KFGKSAGN---AIWLDPYQTSVFDFYGYFVRRSDQ--EVENLLKLFTFMPIsEITKTM 345 Neurospora crassa OR74A
O84589 181 pEPDILQGEl--tALVGTNGQgKMSKSANN---AIYLSDDAKTVQEKIRKLYTDPNR---IHATTPGRVEGNP-LFIYHD 251 Chlamydia trachomatis...
P00954 173 kVPEPFIPKsgarVMSLLEPTkKMSKSDDNrnnVIGLLEDPKSVVKKIKRAVTDSDEppVVRYDVQNKAGVSN-LLDILS 251 Escherichia coli K-12
Q5L1T6 170 tIPEARIPKvgarIMSLVDPTkKMSKSDPNpkaYITLLDDAKTIEKKIKSAVTDSEG--TIRYDKEAKPGISN-LLNIYS 246 Geobacillus kaustophilus
Q49901 183 vVPDMFIPKmaakIYDLADPTsKMSKSASSdagLINLLDDPALSVKKIRAAVTDSER--EIRYDPEVKPGVSN-LLNIQS 259 Mycobacterium leprae TN
P73655 177 kLPEPLIRKegarVMSLADGTkKMSKSDESelsRINLLDPPEMIKKKVKKCKTDPQR--GLWFDDPERPECHN-LLTLYT 253 Synechocystis sp. PCC...
P56396 173 kVPEPLIAKvgarVMGLDDPKvKMSKSHQGanhAIFLLDEPDIIVKKIKKAATDSMG--VIAFDEKRE-GIFN-LLNIYM 248 Helicobacter pylori 2...
O42875 204 tVPDIILNSss-sIMALCQPEkKMSKSDINsknYILLSDSTGEIRKKISRAQTDNIK--GITYGDSNRPGINN-LINIFA 279 Schizosaccharomyces p...
P04803 223 pKPVTMLAQtk-kVLSLSTPEkKMSKSDPNhdsVIFLNDEPKAIQKKIRKALTDSISd-RFYYDPVERPGVSN-LINIVS 299 Saccharomyces cerevis...
P46579 207 pIPKQLTREsharIRSLREPEkKMSKSSGGprsRIEITDSRSTIIEKCQKAQSDNAG--KVTYDKENRLAVSN-LLDLYS 283 Caenorhabditis elegans
4OJM_X 346 EEHIKDPskrVAQHTLAREVVTLVHGKQEASAAEDQHRMMYT 387 Neurospora crassa OR74A
O84589 252 LFNPHKE---EVEEFKTRYRQGCIRDVEVKARLAEEINLFLN 290 Chlamydia trachomatis D/UW-3/CX
P00954 252 AVTGQSI-----PELEKQFEGK--MYGHLKGEVADAVSGMLT 286 Escherichia coli K-12
Q5L1T6 247 TLSGQSI-----EELERQYEGK--GYGVFKADLAQVVIETLr 281 Geobacillus kaustophilus
Q49901 260 AVTGVDV-----DTLVQRYVGH--GYGDLKKDTAEAVVEFVS 294 Mycobacterium leprae TN
P73655 254 LLSNQTK-----EAVAQECAEM--GWGQFKPLLTETAIAALE 288 Synechocystis sp. PCC 6803 substr. Kazusa
P56396 249 LLSNESP-----ENIEERFKNK--GYGDFKKELAEVMIQALK 283 Helicobacter pylori 26695
O42875 280 AISDSTP-----SDIAQANASC--SNAEFKEKVSSAIIRCLQ 314 Schizosaccharomyces pombe 972h-
P04803 300 GIQRKS-----IEDVVEDVSRFN-NYRDFKDYVSEVIIEELK 335 Saccharomyces cerevisiae S288c
P46579 284 AVTKTQT-----SEI--DFSNW--TTLDLKMNLAEAVDKRLA 316 Caenorhabditis elegans
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