1PV9,2ZSG,5CNX,5CDV


Conserved Protein Domain Family
Peptidase_M24

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pfam00557: Peptidase_M24 
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Metallopeptidase family M24
This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Statistics
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PSSM-Id: 334143
View PSSM: pfam00557
Aligned: 442 rows
Threshold Bit Score: 59.9337
Threshold Setting Gi: 1168857
Created: 15-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1PV9_A       131 EIIEKACEIADKAVMAAI--EE--IT---EGKREREVAAKVE-Yl-MKMNG-----AEKP-AFDTIIASGHRSALPHG-V 194 Pyrococcus furi...
O52353        11 QKIKNAAQIYKKIVKQF---NFdyIK----NKSLKEIDQMLR-Df--VSQHhanscYHGYlGFKGYHCLSLNQTIIHGlA 80  Mycoplasma gall...
Q11132        11 EQIRQACKIFQEAKAYFTieR---LL----GKSLTAIDQALKqFi--ESKGatcafHKYQ-NFPGFNCLSLNETVIHG-I 79  Mycoplasma pneu...
Q8EUD4        11 EQIKKACSVWKKVRQAL-------IEnaaAGKSLIELDELAKkVt--IENDcttpfHQYR-GFPGYNCISVNDVVIHG-V 79  Mycoplasma pene...
Q8D2G1        16 IKIRKSCKIASEVLTMI----EnyIE---PGISTEKLNKICH-EyiVKKKHafpasLGYC-GFPKSVCISINDVVCHG-I 85  Wigglesworthia ...
Q8F3E9        11 ekMRAAGKLAARLLDYIS--SY--VQ---PGVSTLQLNDLCE-Ef-TKKHGarsapLGYK-GFPKSICTSVNQVVCHG-I 79  Leptospira inte...
WP_004844059  49 EKIKKSAALNTAVLDEVA--AH--IR---AGMSTAEIDKIVY-DftTAHGGip-apLNYQ-GFPKSVCTSINNEVCHG-I 117 [Ruminococcus] ...
WP_004312787  46 EGIRESAKINTALLDYIS--EN--IR---EGMSTEEIDVLVY-Df-TTSHGaipapLNYE-GFPKSVCTSINEVVCHG-I 114 Bacteroides
WP_011714577  11 EKMRVTCRLAAETLDMI----AphIK---PGVSTETLNTICHdFi--VRNHaipapLNYR-GFPKSICTSVNHQVCHG-I 79  Magnetococcus m...
XP_001611993  91 ALMRAAAKIAAGCLKHC-------INitkEGVTAEDIDREGHeYi--VSQGsypagVGFH-GFPKAICISINEVACHG-I 159 Babesia bovis T2Bo
1PV9_A       195 As-dKRIERGDLVVIDLGALYnhYNSDITRTIVVG-SPNE---K------QREIYEIVLEAQ---KRAVE-AAKP-GMTA 258 Pyrococcus furi...
O52353        81 Nd--EIFTSKDKLTIDIGIELdnYYCDSAFTI-LG---PDvnpR------QKLLSEVTHNCI---FELVKkIV-PnQTTT 144 Mycoplasma gall...
Q11132        80 Ad-nRVFGVKDKLTLDIGINLngYICDAAFTV-LG--------PkapepmQT-LLEVTEACF---TAVVEpQLRPnN-PT 144 Mycoplasma pneu...
Q8EUD4        80 Pt-nYKLKDKDMVTFDVGVAYngYICDAAFTVII----GEnveA------QK-INDVCYKSL---IEGIK-QIKP-GNRI 142 Mycoplasma pene...
Q8D2G1        86 PnkkIILKDGDILNIDVAVIKdeYYGDTSKMFFV----KDvkkE---------AIDLCKSTQkslYLAIK-KIHP-GMRL 150 Wigglesworthia ...
Q8F3E9        80 PkanEVLKEGDIINIDVTPILdgYHGDSSRTFIVGgNTSS---E------VKTLVQDTEKAM---FIGIE-QVRP-GNRV 145 Leptospira inte...
WP_004844059 118 PdenIILQEGDIINVDVSTILdgYFSDASRMFMIG-EVSD---R------AKRLVRVTEECV---ELGLA-AAKPwG-HL 182 [Ruminococcus] ...
WP_004312787 115 PnknEILKSGDIINVDVSTIYkgYFSDASRMFMIG-DVNP---D------MQRLVQVTKECM---EIGIA-AAQP-WKQL 179 Bacteroides
WP_011714577  80 Ps-dRVLRDGDIINVDITTIVdgWHGDTSRTFQVG---TPtkkG------LK-IAEIAKKCL---DLGIA-AVRP-GIHL 143 Magnetococcus m...
XP_001611993 160 Pn-tRPFQRGDIVSYDCTVFHggVYGDCAGTIIVG---DD---SatdasgSL-LVRIAKECV---DKAIA-SVAP-GVEF 226 Babesia bovis T2Bo
1PV9_A       259 KELDSIAREIIK--EYG-YgdYFIHSLG-HGVGLEIHe-wPR-I-Sq----Y-DETVLKEGMVITIEP------------ 314 Pyrococcus furi...
O52353       145 NDLGIWTEEYAK--KYG-Ys-V-IKDFGgHGCGIKIHe-dPIiL-Nyg-tkK-SSELLTPNMVICIEPmffe-------- 207 Mycoplasma gall...
Q11132       145 GNVSHAIQTYFEs-K-GyY--L-LKQFGgHGCGIKVHe-ePL-IlNyg-kpD-TGTKLEPGMVLCIEP------------ 203 Mycoplasma pneu...
Q8EUD4       143 GDISNAIEEYVV--SNGyYi-L-EDFGG-HGCGRKLHe-dPIiL-Nyg-vkN-SGPIIKPNMVLCIEPmilt-------- 205 Mycoplasma pene...
Q8D2G1       151 RKIGSIIQKYIEskN---Ys-IVREYCG-HGIGKCFHe-ePQiL-Hyd-ayD-KEIKLKPGMIFTIEPmvni-------- 213 Wigglesworthia ...
Q8F3E9       146 HDIANAIDDFLT--PKG-Yg-IVRDLMG-HGIGRGFHe-dPQ-I-PhfrqnR-KLAKLEPGMVFTVEPmv---------- 206 Leptospira inte...
WP_004844059 183 GDIADAINTHAQ--ANG-Ys-VVVDIGG-HGIGLEFHe-dPF-V-SyvtpkG-SEMLLVPGMMFTIEPminegspdffvd 253 [Ruminococcus] ...
WP_004312787 180 GDVGAAIQEHAE--KNG-Fs-VVRDLCG-HGVGMQFHe-ePD-V-EhfgrrG-TGMMIVPGMTFTIEPmi---------- 240 Bacteroides
WP_011714577 144 GDIGAIIEDYARqnRCTvV----REYCG-HGIGEKFHe-ePAvL-Hfg-nyG-EGVKLLPGMIFTIEPmv---------- 204 Magnetococcus m...
XP_001611993 227 SKLAEIVTEHASknSLGvI----KEFGG-HFIG-DMMhmpPM-V-Qfc-hpStTRGQMESGQIFTIEPiice-------- 289 Babesia bovis T2Bo
1PV9_A       315 ---GIY------I-P-----------KL--------G-GVRIEDTVLITE 334 Pyrococcus furiosus
O52353       208 kdnRYY------IdPd---------dSWsvkpvnknQyVCHWEHMVLIKE 242 Mycoplasma gallisepticum str. R(low)
Q11132       204 ---MVMtds-daMvMhn--------nSWnvlt-pksRyNCHVEQMYVITT 240 Mycoplasma pneumoniae M129
Q8EUD4       206 edaSYYi-----DkD-----------KWsvia-snhKlSCHWEHMVLVTN 238 Mycoplasma penetrans
Q8D2G1       214 gskNVYt-----GkD-----------GWtvkt-kdkSlSAQYEHTILITN 246 Wigglesworthia glossinidia endosymbiont of Gl...
Q8F3E9       207 -nlGTWqv----nfSkedhwtvttrdG---------KwSAQFEHTVLVTE 242 Leptospira interrogans
WP_004844059 254 ednD-----------------------Wtiyt-iddGlSAQIEYMVLVKE 279 [Ruminococcus] gnavus
WP_004312787 241 -nmGTYevfiddA-D-----------GWtvctddglP-SAQWENMILITE 276 Bacteroides
WP_011714577 205 -nlGKPyik-lmP-D-----------QWtvvt-kdhSlSAQYEHTVLVTE 239 Magnetococcus marinus
XP_001611993 290 gnpEIYt-----WrD-----------GWtiat-cdgGrCAQFEHTVLVTD 322 Babesia bovis T2Bo
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