Conserved Protein Domain Family
T2SSE

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pfam00437: T2SSE 
Type II/IV secretion system protein
This family contains both type II and type IV pathway secretion proteins from bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection.
Statistics
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PSSM-Id: 395350
View PSSM: pfam00437
Aligned: 18 rows
Threshold Bit Score: 245.283
Threshold Setting Gi: 81621032
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9ZDN5        12 LLPFKNLfaEEGINEIMVNKPGE-AWV-EKRGDi--YSKQIPELDSDHLLALGRLVAQSTEQMISEEKPLLSATLP---- 83  Rickettsia prow...
P25953        10 NLIEEAY--LTKASDIHIVPRERdAIIhFRVDH---ALLKKRDMKKEECVRLISHFKFLSAMDIGERRKPQNGSLTlklk 84  Bacillus subtil...
P29480        92 KIASSAT--AYGASDIHFIREDRiCKIkFRVNGtmiDYREILSSEADALMFVLYNVMATTKETTWNRKLPQDANIIlvin 169 Vibrio cholerae...
Q2K2R0        19 gdqLCVAldDSTVVEIMLNPDGK-LFI-ERLGH---GVAPAGEMSSAAAEMVIGTVAHALQSEVDTEQPIISGELPi--- 90  Rhizobium etli ...
Q9A5M4        11 LAPLQPWldRADVTDIWVNRPGE-VWIeTTKGVt--SRLAAPDLTDQALQRLARQIAAASHQGVSREQPLLSASLP---- 83  Caulobacter vib...
Q9KY93        85 LGILEPLleDASITEIMVNGPDA-IFV-ERAGRv--EQLPLRFASHDQLMQTIERIVSTVNRRVDESNPMVDARLP---- 156 Streptomyces co...
Q9HW98        90 FGPLEILlrDPGVSEILVNGPGR-VFV-EREGRl--YQSDLRFIDDHHVLRVIQRILAPLGRRLDESSPMVDARLP---- 161 Pseudomonas aer...
P45759       114 AILSEAI--KETASDIHIETYEKtMSIrFRIDG---VLRTILQPNKKLAALLISRIKVMARLDIAEKRIPQDGRISlrig 188 Escherichia col...
WP_004151936 120 AMLTEAI--KEKASDIHIETYERhLQIrFRVDG---VLREILRPQRRLAALLISRIKVMASLDIAEKRVPQDGRMAlrig 194 Enterobacteriaceae
Q00512       128 AILGEAI--RENASDIHLETFEKrLVVrFRVDG---VLREVLEPKRELAALLVSRIKVMARLDIAEKRIPQDGRISlrvg 202 Pseudomonas aer...
Q9ZDN5        84 -NGYRIQIVFPPACEIgqII--YSIR--KPSGMNL--TLDEYAQMGAFDntateslvdedadilnnflaeKKIKEFIRYA 156 Rickettsia prow...
P25953        85 eGNVHLRMSTLPTINE--ES--LVIRvmPQYNIP---SIDKLSLFPKTG---------------------ATLLSFLKHS 136 Bacillus subtil...
P29480       170 eKAYRFRYAHMPLFGEggKNyhAVVRiiYPSNNFVctNYQDIGYNEADT---------------------DAIARILNTS 228 Vibrio cholerae...
Q2K2R0        91 -GGHRFEGLLPPVVAK--PA--FTIR--RRALRLI--PLDDYVRSAMMT---------------------EHQASTIRSA 140 Rhizobium etli ...
Q9A5M4        84 -NGARVQIIAPPATRGd-LA--LAIR--KHTLSDL--SLSDLAIGGTLAppaltgrada-daqlrallsaGDVEGFLRTA 154 Caulobacter vib...
Q9KY93       157 -SGERVNVIIPPLSLTg-AT--LTIR---RFPRSF--TLQELIGLGSLD---------------------ENMLYLLAGL 206 Streptomyces co...
Q9HW98       162 -DGSRVNAIIPPVALDg-PC--ISIR--KFSQELL--RSADLLAYQSVD---------------------EALLEFLRQA 212 Pseudomonas aer...
P45759       189 rRNIDVRVSTLPSIYG--ER--AVLRllDKNSLQL--SLNNLGMTAADK---------------------QDLENLIQLP 241 Escherichia col...
WP_004151936 195 gRAIDVRVSTLPSSHG--ER--VVLRllDKNSVNL--DLLTLGMPPALL---------------------DRVDALIARP 247 Enterobacteriaceae
Q00512       203 gREVDIRVSTLPSANG--ER--VVLRllDKQAGRL--NLQHLGMSERDR---------------------KLMDETVRKP 255 Pseudomonas aer...
Q9ZDN5       157 visKKNIIISGGTSTGKTTFT--NAALTEIPAI---ERLITVEDAREVVLsSHPNRVHLLASkgg-qgrANVTTQDLIEA 230 Rickettsia prow...
P25953       137 ---HGMLIFTGPTGSGKTTTL--YSLVQYAKKHf-nRNIVTLEDPVETRD-EDVLQVQVNEK-------AGVTYSAGLKA 202 Bacillus subtil...
P29480       229 ---YGLFIVSGTTGSGKSTSLkkYIELLFFNKYkgkGCFVTVEDPVEYLI-SGAQQSSIVADnd---dkTKNPFADAVRS 301 Vibrio cholerae...
Q2K2R0       141 issRLNIIISGGTGSGKTTLA--NAVIAEIVKSapeDRLVILEDTAEIQC-AADNAVLLHTS-------DTVDMARLLKS 210 Rhizobium etli ...
Q9A5M4       155 iqrRKTIVLSGGTSSGKTTLL--NALVKEIPAH---ERLVLIEDAPEIQL-RHENAIGLIAArsd-tgeAQVDAEDLLQA 227 Caulobacter vib...
Q9KY93       207 vqaRFNIIVSGATGTGKTTLL--NALSGLIPES---DRIITIEDSAELQL-QQAHVIRLESRppnvegqGRITIRDLVRN 280 Streptomyces co...
Q9HW98       213 vsrRCNILISGGTGTGKTTLL--NVISGFIDER---ERIVTIEDTAELQL-GHDHVVRLETRppnaegyGEVTARDLIRN 286 Pseudomonas aer...
P45759       242 ---HGIILVTGPTGSGKSTTL--YAILSALNTPg--RNILTVEDPVEYEL-EGIGQTQVNTR-------VDMSFARGLRA 306 Escherichia col...
WP_004151936 248 ---HGIILVTGPTGSGKSTTL--YAALSRLDARe--RNIMTIEDPVEYEL-EGIGQTQVNAK-------VEMTFARGLRA 312 Enterobacteriaceae
Q00512       256 ---HGILLVTGPTGSGKTTTL--YASLTTLNDRt--RNILTVEDPIEYHL-EGIGQTQVNAK-------VDMTFARGLRA 320 Pseudomonas aer...
Q9ZDN5       231 CLRLRPDRIIVGELRGKEAFSF-LRAINTGHPGsISTLHADSPAMAIEQLKLMVmqadfgMPPEEVKKYILSVvdIVVQL 309 Rickettsia prow...
P25953       203 ILRHDPDMIILGEIRDAETAEIaVRAAMTGHLV-LTSLHTRDAKGAIYRLLEFG------INMNEIEQTVIAI--AAQRL 273 Bacillus subtil...
P29480       302 AMRRDPDVIMIGEIRDKPTVEAlSSAVESGHYC-LTTIHAGSVVSVLQRLSGLG------MKADKIASPGFLAgiTSQKL 374 Vibrio cholerae...
Q2K2R0       211 TMRLRPDRIVVGEVRDGAALTL-LKAWNTGHPGgVATIHSNTAMSALRRLEQLTa----eASQQPMHEVIGEAvdLIVSI 285 Rhizobium etli ...
Q9A5M4       228 SLRMRPDRILLGELRGREAFAF-LRAVNTGHPGsITTVHADSPQGALDQIALLSllagvdLGWDTVRNYVRQVvdIVVQL 306 Caulobacter vib...
Q9KY93       281 SLRMRPDRIVVGEVRGGESLDM-LQAMSTGHDGsLATVHANSAEDALMRLQTLAsmsdveIPFVALHDQINSSvdVLIQL 359 Streptomyces co...
Q9HW98       287 ALRMRPDRIILGEIRGVEVLDV-LQAMNTGHDGsMSTVHANSAMDSLLRMEMLVgltgnrLPEQTLRLMICAAldVVVQI 365 Pseudomonas aer...
P45759       307 ILRQDPDVVMVGEIRDTETAQIaVQASLTGHLV-LSTLHTNSASGAVTRLRDMG------VESFLLSSSLAGI--IAQRL 377 Escherichia col...
WP_004151936 313 ILRQDPDVVLVGEIRDGETAQIaVQASLTGHLV-LSTLHTNSALGAISRLQDMG------VEPFLLSTSLLAV--MSQRL 383 Enterobacteriaceae
Q00512       321 ILRQDPDVVMVGEIRDRETAEIaVQASLTGHLV-LSTLHTNSAIGAITRLVDMG------IEPFLLSSSMLGV--LAQRL 391 Pseudomonas aer...
Q9ZDN5       310 KRA 312 Rickettsia prowazekii
P25953       274 VDL 276 Bacillus subtilis subsp. subtilis str. 168
P29480       375 IPE 377 Vibrio cholerae O1 biovar El Tor str. N16961
Q2K2R0       286 ERT 288 Rhizobium etli CFN 42
Q9A5M4       307 NRV 309 Caulobacter vibrioides
Q9KY93       360 TRF 362 Streptomyces coelicolor
Q9HW98       366 TRL 368 Pseudomonas aeruginosa
P45759       378 VRR 380 Escherichia coli K-12
WP_004151936 384 VRQ 386 Enterobacteriaceae
Q00512       392 VRV 394 Pseudomonas aeruginosa PAO1
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