Conserved Protein Domain Family
HN

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pfam00423: HN 
Haemagglutinin-neuraminidase
Statistics
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PSSM-Id: 278832
View PSSM: pfam00423
Aligned: 7 rows
Threshold Bit Score: 584.093
Threshold Setting Gi: 298351700
Created: 12-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P11235        39 SVQAVTLI--LVIVTLGElvrmINDQGLSNQ------------LSSIADKIRESATMIASAVG----VMNQVIHGVTVSL 100 Mumps virus Miy...
Q6YIS0        32 VSTVISLI--IAIISLAF----IIDNKINIQsldplrgledsyLVPIKDKSESISQDIQEGIFp---RLNLITAATTTTI 102 Fer-de-Lance pa...
Q88261        46 ALSIATVI--ICIVIAARqgysMERYSMTVEa----------lNTSNKEVKESLTSLIRQEVIt---RAANIQSSVQTGI 110 Sendai virus (s...
Q786F2        43 FVMFLSLIglLAIAGIRLhraaIYTAEIHKS------------LSTNLDVTNSIEHQVKDVLTp---LFKIIGDEVGLRT 107 Measles virus s...
O89343        50 FNTVIALL--GSIIIIVMnimiIQNYTRTTDnqal----ikesLQSVQQQIKALTDKIGTEIGp---KVSLIDTSSTITI 120 Hendra virus ho...
Q91UL0        31 FLTVVTLA--ISVASL------LYSMGASTPs----------dLVGIPTRISRAEEKITSTLGsnqdVVDRIYKQVALES 92  Newcastle disea...
YP_009094151  44 VLIVLGLI--LAIIGIGIgassFSASGITGNttke----irliVEEMSYGLVRISDSVRQEISp---KVTLLQNAVLSSI 114 Atlantic salmon...
P11235       101 PLQIEGNQNQLLSTLA-------------TICTgKKQV-----------SNCSTNIPLVNDLRFInginkfi-------- 148 Mumps virus Miy...
Q6YIS0       103 PRSIAIQTKDLSDLIM-------------NRCY-PSVVnndtscdvlagAIHSNLFSQLDPSTYW--------------- 153 Fer-de-Lance pa...
Q88261       111 PVLLNKNSRDVIRLIE-------------KSCNrQELTqlcd---stiaVHHAEGIAPLEPHSFW--------------- 159 Sendai virus (s...
Q786F2       108 PQRFTDLVKFISDKIKflnpdreydfrdlTWCInPPERikldydqycadVAAEELMNALVNSTLLearatnq-------- 179 Measles virus s...
O89343       121 PANIGLLGSKISQSTS-------------SINEnVNDKckft---lpplKIHECNISCPNPLPFReyrpisqgvsdlvgl 184 Hendra virus ho...
Q91UL0        93 PLALLNTETTIMNAIT-------------SLSYqINGA-----------ANNSGWGAPIHDPDYIggigkel-------- 140 Newcastle disea...
YP_009094151 115 PALVTTETNTIINAVK-------------NHCNsPPTPpppt---eaplKKHETGMAPLDPTTYW--------------- 163 Atlantic salmon...
P11235       149 --iedyathDFSIGHP----------LNMPSFIPTATSPNGCTRIPSFSLGKTHWCYTHNVINANCKDHT--SSNQYISM 214 Mumps virus Miy...
Q6YIS0       154 ---------TCSSGTPtmnq--tvklLPDNSQIPGSTYSTGCVRIPTFSLGSMIYSYSHNVIYEGCNDHS--KSSQYWQL 220 Fer-de-Lance pa...
Q88261       160 ---------RCPAGEPylssdpevslLPGPSLLSGSTTISGCVRLPSLSIGEAIYAYSSNLITQGCADIG--KSYQVLQL 228 Sendai virus (s...
Q786F2       180 --flavskgNCSGPTTirgqfsnmslSLLDLYLSRGYNVSSIVTMTSQGMYGGTYLVGKPNLSSKGSELSqlSMHRVFEV 257 Measles virus s...
O89343       185 pnqiclqktTSTILKPrli----------syTLPINTREGVCITDPLLAVDNGFFAYSHLEKIGSCTRGI--AKQRIIGV 252 Hendra virus ho...
Q91UL0       141 ---ivddasDVTSFYPsa-------fQEHLNFIPAPTTGSGCTRIPSFDMSATHYCYTHNVILSGCRDHS--HSYQYLAL 208 Newcastle disea...
YP_009094151 164 ---------TCTSGTPrfysspnatfIPGPSPLPHTATPGGCVRIPSMHIGSEIYAYTSNLIASGCQDIG--KSYQNVQI 232 Atlantic salmon...
P11235       215 GILVQTASGYPMFK--TLKIQYLSDGLNRKSCSIATVPDGCAMYCYVSTQLETDDYAGSSPPTQKLTLLFY-----NDTV 287 Mumps virus Miy...
Q6YIS0       221 GYISTSKTGEPLQQ--VSRTLTLNNGLNRKSCSTVAQGRGAYLLCTNVVEDERTDYSTEGIQDLTLDYIDI-----FGAE 293 Fer-de-Lance pa...
Q88261       229 GYISLNSDMFPDLNpvVSHTYDIND--NRKSCSVVATGTRGYQLCSMPIVDERTDYSSDGIEDLVLDILDL-----KGRT 301 Sendai virus (s...
Q786F2       258 GVIRNPGLGAPVFH--MTNYFEQPVSNDFSNCMVALGELKFAALCHREDSITIPYQGSGKGVSFQLVKLGV--------- 326 Measles virus s...
O89343       253 GEVLDRGDKVPSMF--MTNVWTPPNPSTIHHCSSTYHEDFYYTLCAVSHVGDPILNSTSWTESLSLIRLAVrpksdSGDY 330 Hendra virus ho...
Q91UL0       209 GVLRTSATGRVFFS--TLRSINLDDTQNRKSCSVSATPLGCDMLCSKATETEEEDYNSAVPTRMVHGRLGF-----DGQY 281 Newcastle disea...
YP_009094151 233 GVLDRTPEGNPEMSpmLSHTFPIND--NRKSCSIVTLKRAAYIYCSQPKVTEFVDYQTPGIEPMSLDHINA-----NGTT 305 Atlantic salmon...
P11235       288 TERTISPTGLEGN--WATLVPGVGSGIYFENKLIFPAYGGVlpnsslg-vksarefFRPVNPYNPCSGPQ-QDLDQRALR 363 Mumps virus Miy...
Q6YIS0       294 RSYRYTNNEVDLDrpYAALYPSVGSGTVYNDRILFLGYGGL---------------MTPYGDQAMCQAPEcTSATQEGCN 358 Fer-de-Lance pa...
Q88261       302 KSHRYSNSEIDLDhpFSALYPSVGSGIATEGSLIFLGYGGL---------------TTPLQGDTKCRIQGcQQVSQDTCN 366 Sendai virus (s...
Q786F2       327 ---WKSPTDMRSWvpLSTDDPVI-------DRLYLSSHRGViadnqakwavpttrtDDKLRMET-CFQQAcKGKNQALCE 395 Measles virus s...
O89343       331 NQKYIAITKVERGk-YDKVMPYGPSGIKQGDTLYFPAVGFLp-------------rTEFQYNDSNCPIIHcKYSKAENCR 396 Hendra virus ho...
Q91UL0       282 HEKDLDVTTLFGD--WVANYPGVGGGSFIDSRVWFSVYGGLkpnspsdtvqegkyvIYKRYNDT-C--PDeQDYQIRMAK 356 Newcastle disea...
YP_009094151 306 KTWIYSPTEVVTDvpYASMYPSVGSGVVIDGKLVFLVYGGL---------------LNGIQVPAMCLSPEcPGIDQAACN 370 Atlantic salmon...
P11235       364 -SYFPSYFSNRRVQSAFLvcAWNQILVTNCELVVP--SNNQTLMGAEGRVLLINNRLLYYQRSTS---WWPYellyeISF 437 Mumps virus Miy...
Q6YIS0       359 sNQLIGYFSGRQIVNCII--EIITVGTEKPIIRVRtiPNSQVWLGAEGRIQTLGGVLYLYIRSSG---WHAL-----AQT 428 Fer-de-Lance pa...
Q88261       367 eALKITWLGGKQVVSVLI--QVNDYLSERPRIRVTtiPITQNYLGAEGRLLKLGDQVYIYTRSSG---WHSQ-----LQI 436 Sendai virus (s...
Q786F2       396 nPEWAPLKDNRIPSYGVL--SVNLSLTVELKIKIA---------SGFGPLITHGSGMDLYKTNHNnvyWLTIppmknLAL 464 Measles virus s...
O89343       397 lSMGVNSKSHYILRSGLL--KYNLSLGGDIILQFIeiADNRLTIGSPSKIYNSLGQPVFYQASYS---WDTM-----IKL 466 Hendra virus ho...
Q91UL0       357 sSYKPGRFGGKRIQQAILsiKVSTSLGEDPVLTVP--PNTVTLMGAEGRILTVGTSHFLYQRGSS---YFSPal------ 425 Newcastle disea...
YP_009094151 371 aSQYNQYLSGRQVVNGIA--TVDLMNGQKPHISVEtiSPSKNWFGAEGRLVYMGGRLYIYIRSTG---WHSP-----IQI 440 Atlantic salmon...
P11235       438 TFTNSgQSSVNMSWIPIYSFT--------RPGSGNCSGENVCPTACVSGVYLDPWPLTPYSHQsginrnfyFTGALLNSS 509 Mumps virus Miy...
Q6YIS0       429 GIILT-LDPIRISWIVNTGYS--------RPGNGPCSASSRCPAQCITGVYTDIFPLSQNYGY--------LATVTLLSG 491 Fer-de-Lance pa...
Q88261       437 GVLDV-SHPLTISWTPHEALS--------RPGNEDCNWYNTCPKECISGVYTDAYPLSPDAAN--------VATVTLYAN 499 Sendai virus (s...
Q786F2       465 GVINT------LEWIPRFKVSpnlftvpiKEAGEDCHAPTYLPAEVDGDVKLSSNLVILPGQD--------LQYVLATYD 530 Measles virus s...
O89343       467 GDVDT-VDPLRVQWRNNSVIS--------RPGQSQCPRFNVCPEVCWEGTYNDAFLIDrln--------wvSAGVYLNSN 529 Hendra virus ho...
Q91UL0       426 ------lyPMTVSNKTATLHSpytfnaftRPGSIPCQASARCPNSCVTGVYTDPYPLIFYRNHtl----rgVFGTMLDGE 495 Newcastle disea...
YP_009094151 441 GVIYT-MNPLAITWVTNTVLS--------RPGSAGCDWNNRCPKACLSGVYTDAYPISPDYNH--------LATMILHST 503 Atlantic salmon...
P11235       510 TTRVNPTLYVSALNNLKVLAPYGNQGLFASY--------------TTTTCFqdTGDASVYCVYIMELASNIVGEFQILPV 575 Mumps virus Miy...
Q6YIS0       492 VDRVNPVISYGTSTGRVADSQLTSSSQVAAY--------------TTTTCF--TFNQKGYCYHIIELSPATLGIFQPVLV 555 Fer-de-Lance pa...
Q88261       500 TSRVNPTIMYSNTTNIINMLRIKDVQLEAAY--------------TTTSCI--THFGKGYCFHIIEINQKSLNTLQPMLF 563 Sendai virus (s...
Q786F2       531 TSRVEHAVVYY----------VYSPSRSFSYfypfrlpikgvpieLQVECF--TWDKKLWCRHFCVLADSESGGHITHSG 598 Measles virus s...
O89343       530 QTAENPVFAVFKDNEILYQVPLAEDDTNAQK--------------TITDCF--LLENVIWCISLVEIYDTGDSVIRPKLF 593 Hendra virus ho...
Q91UL0       496 QARLNPASAVFDSTSRSRITRVSSSSIKAAY--------------TTSTCFkvVKTNKTYCLSIAEISNTLFGEFRIVPL 561 Newcastle disea...
YP_009094151 504 STRSNPVMVYSSPTNMVNYAQLTTTAQIAGY--------------TTTSCF--TDNEVGYCATALELTPGTLSSVQPILV 567 Atlantic salmon...
P11235       576 LTRLTI 581 Mumps virus Miyahara vaccine
Q6YIS0       556 VTEIPK 561 Fer-de-Lance paramyxovirus
Q88261       564 KTSIPK 569 Sendai virus (strain Ohita)
Q786F2       599 MVGMGV 604 Measles virus strain Ichinose-B95a
O89343       594 AVKIPA 599 Hendra virus horse/Australia/Hendra/1994
Q91UL0       562 LVEILK 567 Newcastle disease virus B1/48
YP_009094151 568 MTKIPK 573 Atlantic salmon paramyxovirus
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