Conserved Protein Domain Family
HN

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pfam00423: HN 
Haemagglutinin-neuraminidase
Statistics
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Aligned: 7 rows
Threshold Bit Score: 584.093
Threshold Setting Gi: 298351700
Created: 22-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P11235        39 SVQAVTLI--LVIVTLGElvrmINDQGLSNQ------------LSSIADKIRESATMIASAVG----VMNQVIHGVTVSL 100 Mumps virus Miy...
Q6YIS0        32 VSTVISLI--IAIISLAF----IIDNKINIQsldplrgledsyLVPIKDKSESISQDIQEGIFp---RLNLITAATTTTI 102 Reptilian ferla...
Q88261        46 ALSIATVI--ICIVIAARqgysMERYSMTVEa----------lNTSNKEVKESLTSLIRQEVIt---RAANIQSSVQTGI 110 Sendai virus (s...
Q786F2        43 FVMFLSLIglLAIAGIRLhraaIYTAEIHKS------------LSTNLDVTNSIEHQVKDVLTp---LFKIIGDEVGLRT 107 Measles virus s...
O89343        50 FNTVIALL--GSIIIIVMnimiIQNYTRTTDnqal----ikesLQSVQQQIKALTDKIGTEIGp---KVSLIDTSSTITI 120 Hendra virus ho...
Q91UL0        31 FLTVVTLA--ISVASL------LYSMGASTPs----------dLVGIPTRISRAEEKITSTLGsnqdVVDRIYKQVALES 92  Newcastle disea...
YP_009094151  44 VLIVLGLI--LAIIGIGIgassFSASGITGNttke----irliVEEMSYGLVRISDSVRQEISp---KVTLLQNAVLSSI 114 Salmon aquapara...
P11235       101 PLQIEGNQNQLLSTLA-------------TICTgKKQV-----------SNCSTNIPLVNDLRFInginkfi-------- 148 Mumps virus Miy...
Q6YIS0       103 PRSIAIQTKDLSDLIM-------------NRCY-PSVVnndtscdvlagAIHSNLFSQLDPSTYW--------------- 153 Reptilian ferla...
Q88261       111 PVLLNKNSRDVIRLIE-------------KSCNrQELTqlcd---stiaVHHAEGIAPLEPHSFW--------------- 159 Sendai virus (s...
Q786F2       108 PQRFTDLVKFISDKIKflnpdreydfrdlTWCInPPERikldydqycadVAAEELMNALVNSTLLearatnq-------- 179 Measles virus s...
O89343       121 PANIGLLGSKISQSTS-------------SINEnVNDKckft---lpplKIHECNISCPNPLPFReyrpisqgvsdlvgl 184 Hendra virus ho...
Q91UL0        93 PLALLNTETTIMNAIT-------------SLSYqINGA-----------ANNSGWGAPIHDPDYIggigkel-------- 140 Newcastle disea...
YP_009094151 115 PALVTTETNTIINAVK-------------NHCNsPPTPpppt---eaplKKHETGMAPLDPTTYW--------------- 163 Salmon aquapara...
P11235       149 --iedyathDFSIGHP----------LNMPSFIPTATSPNGCTRIPSFSLGKTHWCYTHNVINANCKDHT--SSNQYISM 214 Mumps virus Miy...
Q6YIS0       154 ---------TCSSGTPtmnq--tvklLPDNSQIPGSTYSTGCVRIPTFSLGSMIYSYSHNVIYEGCNDHS--KSSQYWQL 220 Reptilian ferla...
Q88261       160 ---------RCPAGEPylssdpevslLPGPSLLSGSTTISGCVRLPSLSIGEAIYAYSSNLITQGCADIG--KSYQVLQL 228 Sendai virus (s...
Q786F2       180 --flavskgNCSGPTTirgqfsnmslSLLDLYLSRGYNVSSIVTMTSQGMYGGTYLVGKPNLSSKGSELSqlSMHRVFEV 257 Measles virus s...
O89343       185 pnqiclqktTSTILKPrli----------syTLPINTREGVCITDPLLAVDNGFFAYSHLEKIGSCTRGI--AKQRIIGV 252 Hendra virus ho...
Q91UL0       141 ---ivddasDVTSFYPsa-------fQEHLNFIPAPTTGSGCTRIPSFDMSATHYCYTHNVILSGCRDHS--HSYQYLAL 208 Newcastle disea...
YP_009094151 164 ---------TCTSGTPrfysspnatfIPGPSPLPHTATPGGCVRIPSMHIGSEIYAYTSNLIASGCQDIG--KSYQNVQI 232 Salmon aquapara...
P11235       215 GILVQTASGYPMFK--TLKIQYLSDGLNRKSCSIATVPDGCAMYCYVSTQLETDDYAGSSPPTQKLTLLFY-----NDTV 287 Mumps virus Miy...
Q6YIS0       221 GYISTSKTGEPLQQ--VSRTLTLNNGLNRKSCSTVAQGRGAYLLCTNVVEDERTDYSTEGIQDLTLDYIDI-----FGAE 293 Reptilian ferla...
Q88261       229 GYISLNSDMFPDLNpvVSHTYDIND--NRKSCSVVATGTRGYQLCSMPIVDERTDYSSDGIEDLVLDILDL-----KGRT 301 Sendai virus (s...
Q786F2       258 GVIRNPGLGAPVFH--MTNYFEQPVSNDFSNCMVALGELKFAALCHREDSITIPYQGSGKGVSFQLVKLGV--------- 326 Measles virus s...
O89343       253 GEVLDRGDKVPSMF--MTNVWTPPNPSTIHHCSSTYHEDFYYTLCAVSHVGDPILNSTSWTESLSLIRLAVrpksdSGDY 330 Hendra virus ho...
Q91UL0       209 GVLRTSATGRVFFS--TLRSINLDDTQNRKSCSVSATPLGCDMLCSKATETEEEDYNSAVPTRMVHGRLGF-----DGQY 281 Newcastle disea...
YP_009094151 233 GVLDRTPEGNPEMSpmLSHTFPIND--NRKSCSIVTLKRAAYIYCSQPKVTEFVDYQTPGIEPMSLDHINA-----NGTT 305 Salmon aquapara...
P11235       288 TERTISPTGLEGN--WATLVPGVGSGIYFENKLIFPAYGGVlpnsslg-vksarefFRPVNPYNPCSGPQ-QDLDQRALR 363 Mumps virus Miy...
Q6YIS0       294 RSYRYTNNEVDLDrpYAALYPSVGSGTVYNDRILFLGYGGL---------------MTPYGDQAMCQAPEcTSATQEGCN 358 Reptilian ferla...
Q88261       302 KSHRYSNSEIDLDhpFSALYPSVGSGIATEGSLIFLGYGGL---------------TTPLQGDTKCRIQGcQQVSQDTCN 366 Sendai virus (s...
Q786F2       327 ---WKSPTDMRSWvpLSTDDPVI-------DRLYLSSHRGViadnqakwavpttrtDDKLRMET-CFQQAcKGKNQALCE 395 Measles virus s...
O89343       331 NQKYIAITKVERGk-YDKVMPYGPSGIKQGDTLYFPAVGFLp-------------rTEFQYNDSNCPIIHcKYSKAENCR 396 Hendra virus ho...
Q91UL0       282 HEKDLDVTTLFGD--WVANYPGVGGGSFIDSRVWFSVYGGLkpnspsdtvqegkyvIYKRYNDT-C--PDeQDYQIRMAK 356 Newcastle disea...
YP_009094151 306 KTWIYSPTEVVTDvpYASMYPSVGSGVVIDGKLVFLVYGGL---------------LNGIQVPAMCLSPEcPGIDQAACN 370 Salmon aquapara...
P11235       364 -SYFPSYFSNRRVQSAFLvcAWNQILVTNCELVVP--SNNQTLMGAEGRVLLINNRLLYYQRSTS---WWPYellyeISF 437 Mumps virus Miy...
Q6YIS0       359 sNQLIGYFSGRQIVNCII--EIITVGTEKPIIRVRtiPNSQVWLGAEGRIQTLGGVLYLYIRSSG---WHAL-----AQT 428 Reptilian ferla...
Q88261       367 eALKITWLGGKQVVSVLI--QVNDYLSERPRIRVTtiPITQNYLGAEGRLLKLGDQVYIYTRSSG---WHSQ-----LQI 436 Sendai virus (s...
Q786F2       396 nPEWAPLKDNRIPSYGVL--SVNLSLTVELKIKIA---------SGFGPLITHGSGMDLYKTNHNnvyWLTIppmknLAL 464 Measles virus s...
O89343       397 lSMGVNSKSHYILRSGLL--KYNLSLGGDIILQFIeiADNRLTIGSPSKIYNSLGQPVFYQASYS---WDTM-----IKL 466 Hendra virus ho...
Q91UL0       357 sSYKPGRFGGKRIQQAILsiKVSTSLGEDPVLTVP--PNTVTLMGAEGRILTVGTSHFLYQRGSS---YFSPal------ 425 Newcastle disea...
YP_009094151 371 aSQYNQYLSGRQVVNGIA--TVDLMNGQKPHISVEtiSPSKNWFGAEGRLVYMGGRLYIYIRSTG---WHSP-----IQI 440 Salmon aquapara...
P11235       438 TFTNSgQSSVNMSWIPIYSFT--------RPGSGNCSGENVCPTACVSGVYLDPWPLTPYSHQsginrnfyFTGALLNSS 509 Mumps virus Miy...
Q6YIS0       429 GIILT-LDPIRISWIVNTGYS--------RPGNGPCSASSRCPAQCITGVYTDIFPLSQNYGY--------LATVTLLSG 491 Reptilian ferla...
Q88261       437 GVLDV-SHPLTISWTPHEALS--------RPGNEDCNWYNTCPKECISGVYTDAYPLSPDAAN--------VATVTLYAN 499 Sendai virus (s...
Q786F2       465 GVINT------LEWIPRFKVSpnlftvpiKEAGEDCHAPTYLPAEVDGDVKLSSNLVILPGQD--------LQYVLATYD 530 Measles virus s...
O89343       467 GDVDT-VDPLRVQWRNNSVIS--------RPGQSQCPRFNVCPEVCWEGTYNDAFLIDrln--------wvSAGVYLNSN 529 Hendra virus ho...
Q91UL0       426 ------lyPMTVSNKTATLHSpytfnaftRPGSIPCQASARCPNSCVTGVYTDPYPLIFYRNHtl----rgVFGTMLDGE 495 Newcastle disea...
YP_009094151 441 GVIYT-MNPLAITWVTNTVLS--------RPGSAGCDWNNRCPKACLSGVYTDAYPISPDYNH--------LATMILHST 503 Salmon aquapara...
P11235       510 TTRVNPTLYVSALNNLKVLAPYGNQGLFASY--------------TTTTCFqdTGDASVYCVYIMELASNIVGEFQILPV 575 Mumps virus Miy...
Q6YIS0       492 VDRVNPVISYGTSTGRVADSQLTSSSQVAAY--------------TTTTCF--TFNQKGYCYHIIELSPATLGIFQPVLV 555 Reptilian ferla...
Q88261       500 TSRVNPTIMYSNTTNIINMLRIKDVQLEAAY--------------TTTSCI--THFGKGYCFHIIEINQKSLNTLQPMLF 563 Sendai virus (s...
Q786F2       531 TSRVEHAVVYY----------VYSPSRSFSYfypfrlpikgvpieLQVECF--TWDKKLWCRHFCVLADSESGGHITHSG 598 Measles virus s...
O89343       530 QTAENPVFAVFKDNEILYQVPLAEDDTNAQK--------------TITDCF--LLENVIWCISLVEIYDTGDSVIRPKLF 593 Hendra virus ho...
Q91UL0       496 QARLNPASAVFDSTSRSRITRVSSSSIKAAY--------------TTSTCFkvVKTNKTYCLSIAEISNTLFGEFRIVPL 561 Newcastle disea...
YP_009094151 504 STRSNPVMVYSSPTNMVNYAQLTTTAQIAGY--------------TTTSCF--TDNEVGYCATALELTPGTLSSVQPILV 567 Salmon aquapara...
P11235       576 LTRLTI 581 Mumps virus Miyahara vaccine
Q6YIS0       556 VTEIPK 561 Reptilian ferlavirus
Q88261       564 KTSIPK 569 Sendai virus (strain Ohita)
Q786F2       599 MVGMGV 604 Measles virus strain Ichinose-B95a
O89343       594 AVKIPA 599 Hendra virus horse/Australia/Hendra/1994
Q91UL0       562 LVEILK 567 Newcastle disease virus B1/48
YP_009094151 568 MTKIPK 573 Salmon aquaparamyxovirus
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