5NT7,2JGN,4D25,5GI4,2KBF,4NHO,5IVL,1HV8,4CRW,3FHT,5ZWN,2YJT,2RB4,3FHO,6FML,5HZR,3I32,1T5I,6GEJ,5VVR,1Z3I,4DB2,5GN1,2FWR,4S20,1GM5,4U7D,1C4O,6GPG,5AOR,5LQW,3RC8


Conserved Protein Domain Family
Helicase_C

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pfam00271: Helicase_C 
Click on image for an interactive view with Cn3D
Helicase conserved C-terminal domain
The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Statistics
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PSSM-Id: 365992
View PSSM: pfam00271
Aligned: 452 rows
Threshold Bit Score: 45.6683
Threshold Setting Gi: 119628
Created: 19-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5NT7_B    16 AKRSKLIEI-L-----SEQADGTIVFVETKRgadFLA-----------SFL---SEKE--FPTTSIHGD---------RL 64   fruit fly
Q9RZ22   312 ARNALIADT-Yaq--nRERYGQTIIFADRWYqctALV-----------ELLr-qRGVRadAIFTHRDADpgtvdvrnaRS 376  Deinococcus radiod...
Q9RD88   452 DKISDPGAM------------RALGFCVTKA---HA------------HFMadyFRRAg-FQAAALDSD---------SS 494  Streptomyces coeli...
Q9T1H9   198 GKNIVYGDV-IqsyhkFANNTKAIIYSYSVH---SCQ-----------QIAk-eFNKNn-IPAKEVDGK---------TK 251  Lactobacillus phag...
P24125   170 LGKTIFGDV-VqeyvkHANGQKAILYAHSVE---ASQ-----------SFAk-eFQEAg-IKAVHVDAK---------TP 223  Lactococcus phage ...
Q9T0Y3   197 VPKAIFGDV-VshyqhLAGGRQAIVYAHSIE---ASK-----------QVVe-aFQSAg-ITAVHADAK---------TP 250  Lactobacillus phag...
Q1MTR1   249 KAIFEIPRAwLe---hASNRSSTLVFCINVEh--SL------------KVCn-aFRKLg-IDARALFGE---------TN 300  Schizosaccharomyce...
P33919   237 ITPHIISQI-Me---fAATRKGVMIFAATVE---HAK-----------EIV---GLLPa-EDAALITGD---------TP 285  Escherichia coli K-12
STL27114 231 ELTNYLDPT---------GSQKTLVFCVTNA---HADmvveelraafkKKY---PQLEh-DAIIKITGD---------AD 285  Escherichia coli
EGA83433 141 EINEVILKTyLhk-kqEKSLKSTLLFGVDKAhvqSL------------HKL---FKDNg-INTDYVTSD---------TK 194  Saccharomyces cere...
5NT7_B    65 QSQRE--QALRDFKNGSMK-VLIATSVASRGLDIKNIKHVINYDMP-SKIDDYVHRIGRTGRVG 124  fruit fly
Q9RZ22   377 ADENE--TVLAQFKRGELD-VLVNIRMLTEGTDVPGAQTVFLTRQT-TSRILLTQMVGRALRGp 436  Deinococcus radiodurans
Q9RD88   495 SEVRA--QALRDLQDGKLQ-VIFSVDLFNEGLDIPDVDTLLLLRPT-NSATVFLQQLGRGLRRT 554  Streptomyces coelicolor
Q9T1H9   252 KEDRD--KAMQDFRDGKIK-ILVNAELYGEGVDVPDCETVIMLRPT-QSLSLFIQQSMRCMRYQ 311  Lactobacillus phage phiadh
P24125   224 KNERD--KLMLDFRNGRIK-VLCNVDLISEGFDVPDCTVTILCRPT-KSLVLFLQQSMRSMRYQ 283  Lactococcus phage (ISOLATE 7-9)
Q9T0Y3   251 KGQRD--RIMADFKAGKIT-ILSNVDLISEGFNVPDVGVIIMLRPT-ASLVLDIQQSMRGMRYK 310  Lactobacillus phage A2
Q1MTR1   301 DSERE--TLIQDFRKKKFP-VLVNCMVLTEGTDIPNIDCLMIARPTsSp-NLLTQMIGRGLRLH 360  Schizosaccharomyces pombe 972h-
P33919   286 GAERD--VLIENFKAQRFR-YLVNVAVLTTGFDAPHVDLIAILRPT-ESVSLYQQIVGRGLRLA 345  Escherichia coli K-12
STL27114 286 KDARKvqTMITRFNKERLPnIVVTVDLLTTGVDIPSICNIVFLRKV-RSRILYEQMKGRATRLC 348  Escherichia coli
EGA83433 195 QIERD--NIIQKFKNGETE-VLMNCGIFTEGTDMPNIDCILLCRPT-KSRSLLIQMIGRGLRLH 254  Saccharomyces cerevisiae Lalvin QA23
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