2JGN,2DB3,4D25,1HV8,4NHO,2KBF,4CRW,3FHT,2YJT,3FHO,4W7S,1T5I,3I32,4DB2,5GN1,1Z3I,4LK2,3UWX,4U7D,1GM5,4S20,2FWR,3TMI,3RC8,5LQW,5IVW


Conserved Protein Domain Family
Helicase_C

?
pfam00271: Helicase_C 
Click on image for an interactive view with Cn3D
Helicase conserved C-terminal domain
The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Statistics
?
PSSM-Id: 333970
View PSSM: pfam00271
Aligned: 448 rows
Threshold Bit Score: 43.3487
Threshold Setting Gi: 119628
Created: 14-Mar-2017
Updated: 23-May-2017
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2JGN_A        31 DKRSFLLDLL---NATGKDSLTLVFVETKK---G-ADS-----LEDFlyHE---------GYACTSIHGDRSQRDREEAL 89
gi 1170244   442 DKIDWLIDFL----KLHRNEKIFVICQTAAtaiQ-LE-------QIL--REr-------eAIRAAVFHEKMSIIERDRAA 500
gi 74579120  465 SKAQMLKQFVdriLTEDPDEKILIFTEYTD---T-L--------EYLrdRVf-------aEYDIAQVYGDLDQDRRRQEM 525
gi 74579106  382 KKTERLVQVVn--EHMEKGNKVIIFTQFLA---T-LDHl----ERTFkeIYg--------ENSVVTVHGGLTHEEKKNRI 443
gi 74581797  442 ELPDEFKDL--------ASQKAIVFTEFKD---T-A--------TYLyeKLrkwaedefgDPGIVRVFT-SENRGEIEDI 500
gi 74579167  337 SKLEVISDIIa--YHIRKGEKVIIFTEFRD---T-LEYilgklPGILreRHgil----leSDDIAKLHGGMKSEEIEREI 406
gi 81859164  348 SKLKTLAEVLa--YHLKKNEKVIVFTEFKD---T-LEYlr-nnLPTLleQEgih---lseEKDISVLHGGMKSEEIEKQV 417
gi 74581668  382 TKLNIVANVVk--QHVERGEKVIIFTEFKD---T-LEYlr-knLPSLagLS---------DEDVSILHGGMPSGKVEEEI 445
gi 1731040   359 SKALQVVDLI-----KKIDDKVIIFTEYRAtqiY-LQ-------WFL--QQn--------GISSVPFRGGFKRGKKDWMK 415
4S20_K       495 pRVEWLMGYL----TSHRSQKVLVICAKAA---TaLQL-----EQVLreRE---------GIRAAVFHEGMSIIERDRAA 553
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
2JGN_A        90 HQFR----SGKS--P-ILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 141
gi 1170244   501 AYFAdlenGAQ-----VLLSSSIGSEGRNFQFAANLVLFDLPTNPDLLEQCIGRLDRIG 554
gi 74579120  526 ADF-----ENEK--N-IMIATDAAQEGLNLQFAHIMANFDLPWSPTRIDQRMGRLHRYG 576
gi 74579106  444 AKL-----WDSA--K-ILIATDAAGESLNLQAANVVIHYEIPWNPVVYIQRVGRVYRYG 494
gi 74581797  501 KRWL----SEDG--RrVLVTTDVAGEGLNLQYANVIINYEITWSPIRLEQRIGRVWRYG 553
gi 74579167  407 KKF-----HERS--D-LLVSTDVASEGLNLHVASVVINYEAPWSPIKLEQRVGRIWRLN 457
gi 81859164  418 EKFAn---DGK-----LLISTDVASEGLNLQVANILINYEIPWSPIKLEQRVGRIWRLN 468
gi 74581668  446 RKF-----EKHG--K-LLISTDVASEGLNLQVANVLINYEAPWTPIKLEQRVGRVWRIN 496
gi 1731040   416 DLFR----G-KI--Q-VLIATEAGGEGINLQFCNHMINYDLPWNPMRLEQRIGRIHRLG 466
4S20_K       554 AWFA----EEDTgaQ-VLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIG 607
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap