1HV8,4LK2,3I5X,2YJT,4BRU,3FHO,6B4K,2RB4,3RRM,5ZAM,1C4O,6JDE,3RC8,6IY2,6IGM,6GEN,6HTS,5GN1,5VVR,4S20,5AOR,6H57,6ACA,1GM5,2FWR,4D25,4NHO,4W7S


Conserved Protein Domain Family
Helicase_C

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pfam00271: Helicase_C 
Click on image for an interactive view with Cn3D
Helicase conserved C-terminal domain
The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Statistics
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PSSM-Id: 395209
View PSSM: pfam00271
Aligned: 421 rows
Threshold Bit Score: 45.666
Threshold Setting Gi: 119628
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1HV8_B  225 ERFEALCRL-L--------KNKEFygLVFCKTKRdt--kEL-----ASX---------LR---DI---GFKAGAIHG-DL 272  Methanocaldococcus ...
P20634  350 TYGGLVIKY-----------------IMLSNGYSey--nGSqgtnpHMI--------------NGk--PKTFAIVTS--K 392  Vaccinia virus Cope...
Q89525  553 ILQEILQSNgIlnevsspvGTTRC--SICAAIRDeh--tHSd---hQFI-------------------PVRFTILHS-EI 605  African swine fever...
P05470  274 SKINAFINS-Ik-------EGELT--VLFSFYVKrg--idF-----TSSvlesigykkwnsnkkQ---KRTYAVIDG-RT 332  Kluyveromyces lacti...
Q04332  257 SKISRVIET-Lk-------DGELT--VIFCFYVKrgidfMA-----KVLehfgyrkwdPL---YN---GKSYAVIDG-RT 314  Lachancea kluyveri
O37319  375 CKYIEACRI-Il------nSRGKV--LLFEPLVN-----FEg---iASL--------------KYyfnCFNITYVEYsSK 423  Heliothis armigera ...
Q9YW39  375 CKYIEACKI-Il------nSNGKV--LLYEPLVS-----FEg---iSTL--------------KIyfnIFNISYVEYsSK 423  Melanoplus sanguini...
O72907  368 CKFTFVCVS-Ii------qSKGKC--LVFEPFIR-----SSg---iEIL--------------LQyfnVFGITYIEFsSR 416  Fowlpox virus strai...
P33066  366 AKFIDVCLG-Il------aSHGKC--LVFEPFVN-----QSg---iEIL--------------LLyfkVFGISNIEFsSR 414  Variola virus human...
Q98267  365 CKYAEVCVA-Il------aSPGKC--LVFEPFIN-----LSg---iRIF--------------VKyleVFGISYIEFsSR 413  Molluscum contagios...
1HV8_B  273 SQSQREKVIRLFK-----QKKIR-ILIATDVXSRGIDVNDLNCVINYHLPQNPESYXHRIGRTGRAG 333  Methanocaldococcus jannaschii
P20634  393 MKSSLEDLLDVYNspendDGSQLmFLFSSNIMSESYTLKEVRHIWFMTIPDTFSQYNQILGRSIRKF 459  Vaccinia virus Copenhagen
Q89525  606 EPAVRERSLALFNassnlEGHQLrILIGSKVIVEGLNFQAVRYEMIMSLPLDIPRLIQVFGRVVRKN 672  African swine fever virus BA71V
P05470  333 NKKNVEEILTSFNsianiKGDNIhILLGSSVLSESITLYRVKHLHIISPFWNYGQIKQSIGRAIRIG 399  Kluyveromyces lactis NRRL Y-1140
Q04332  315 SHKDVKEILKVFNsiantNGKQIqVLIGSSVLSESITLYRIRHLHILSPFWNYGQVKQSIGRGVRIG 381  Lachancea kluyveri
O37319  424 TLKTRDIEISEYNnyennDGKNIkVCIFSYAGSEGISFKCVNDIIILDMPWNESELKQIMGRSIRLN 490  Heliothis armigera entomopoxvirus
Q9YW39  424 TESTRDYNIDIFNkydnlYGNKIkVCIFSAAGSEGISFSSINDIIILDLPWKESDIKQIIGRSIRLN 490  Melanoplus sanguinipes entomopox...
O72907  417 TKDIRSKSVSDFNkvdntDGEITkVCVFSQSGNEGISFLSINDIFILDMTWNEASLKQIIGRAIRLN 483  Fowlpox virus strain NVSL
P33066  415 TKDTRIKAVAEFNqesntNGECIkTCVFSSSGGEGISFFSINDIFILDMTWNEASLRQIVGRAIRLN 481  Variola virus human/India/Ind3/1967
Q98267  414 TKDTRTRAVAEFNrventNGELIkTCVFSLSGNEGISFLSINDIFILDMTWNEASLKQIIGRAIRLH 480  Molluscum contagiosum virus subt...
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