2JGN,2DB3,4D25,1HV8,4NHO,2KBF,4CRW,3FHT,2YJT,3FHO,4W7S,1T5I,3I32,4DB2,5GN1,1Z3I,4LK2,3UWX,4U7D,1GM5,4S20,2FWR,3TMI,3RC8,5LQW,5IVW


Conserved Protein Domain Family
Helicase_C

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pfam00271: Helicase_C 
Click on image for an interactive view with Cn3D
Helicase conserved C-terminal domain
The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Statistics
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PSSM-Id: 333970
View PSSM: pfam00271
Aligned: 448 rows
Threshold Bit Score: 43.3487
Threshold Setting Gi: 119628
Created: 14-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2JGN_A   31 DKRSFLLDLL---NATGKDSLTLVFVETKK---G-ADS-----LEDFlyHE---------GYACTSIHGDRSQRDREEAL 89   human
P44781  442 DKIDWLIDFL----KLHRNEKIFVICQTAAtaiQ-LE-------QIL--REr-------eAIRAAVFHEKMSIIERDRAA 500  Haemophilus influen...
O52003  465 SKAQMLKQFVdriLTEDPDEKILIFTEYTD---T-L--------EYLrdRVf-------aEYDIAQVYGDLDQDRRRQEM 525  Halobacterium salin...
O30320  382 KKTERLVQVVn--EHMEKGNKVIIFTQFLA---T-LDHl----ERTFkeIYg--------ENSVVTVHGGLTHEEKKNRI 443  Archaeoglobus fulgidus
Q9YF27  442 ELPDEFKDL--------ASQKAIVFTEFKD---T-A--------TYLyeKLrkwaedefgDPGIVRVFT-SENRGEIEDI 500  Aeropyrum pernix
O58633  337 SKLEVISDIIa--YHIRKGEKVIIFTEFRD---T-LEYilgklPGILreRHgil----leSDDIAKLHGGMKSEEIEREI 406  Pyrococcus horikoshii
Q9X085  348 SKLKTLAEVLa--YHLKKNEKVIVFTEFKD---T-LEYlr-nnLPTLleQEgih---lseEKDISVLHGGMKSEEIEKQV 417  Thermotoga maritima
Q9V0B0  382 TKLNIVANVVk--QHVERGEKVIIFTEFKD---T-LEYlr-knLPSLagLS---------DEDVSILHGGMPSGKVEEEI 445  Pyrococcus abyssi
P54509  359 SKALQVVDLI-----KKIDDKVIIFTEYRAtqiY-LQ-------WFL--QQn--------GISSVPFRGGFKRGKKDWMK 415  Bacillus subtilis s...
4S20_K  495 pRVEWLMGYL----TSHRSQKVLVICAKAA---TaLQL-----EQVLreRE---------GIRAAVFHEGMSIIERDRAA 553  Escherichia coli
2JGN_A   90 HQFR----SGKS--P-ILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 141  human
P44781  501 AYFAdlenGAQ-----VLLSSSIGSEGRNFQFAANLVLFDLPTNPDLLEQCIGRLDRIG 554  Haemophilus influenzae Rd KW20
O52003  526 ADF-----ENEK--N-IMIATDAAQEGLNLQFAHIMANFDLPWSPTRIDQRMGRLHRYG 576  Halobacterium salinarum
O30320  444 AKL-----WDSA--K-ILIATDAAGESLNLQAANVVIHYEIPWNPVVYIQRVGRVYRYG 494  Archaeoglobus fulgidus
Q9YF27  501 KRWL----SEDG--RrVLVTTDVAGEGLNLQYANVIINYEITWSPIRLEQRIGRVWRYG 553  Aeropyrum pernix
O58633  407 KKF-----HERS--D-LLVSTDVASEGLNLHVASVVINYEAPWSPIKLEQRVGRIWRLN 457  Pyrococcus horikoshii
Q9X085  418 EKFAn---DGK-----LLISTDVASEGLNLQVANILINYEIPWSPIKLEQRVGRIWRLN 468  Thermotoga maritima
Q9V0B0  446 RKF-----EKHG--K-LLISTDVASEGLNLQVANVLINYEAPWTPIKLEQRVGRVWRIN 496  Pyrococcus abyssi
P54509  416 DLFR----G-KI--Q-VLIATEAGGEGINLQFCNHMINYDLPWNPMRLEQRIGRIHRLG 466  Bacillus subtilis subsp. subtilis str. 168
4S20_K  554 AWFA----EEDTgaQ-VLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIG 607  Escherichia coli
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