1IA0,1MKJ,1T5C,3LRE,2WBE,1SDM


Conserved Protein Domain Family
Kinesin

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pfam00225: Kinesin 
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Kinesin motor domain
Statistics
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PSSM-Id: 333938
View PSSM: pfam00225
Aligned: 77 rows
Threshold Bit Score: 301.015
Threshold Setting Gi: 51316544
Created: 14-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1IA0_K         27 RVRPFNSREMSRDSKCIIqms-----------gstTTIVNPKQPKETPKSFSFDYSYWS--HtspedinyAS-----QKQ 88   house mouse
Q9UTL2         11 RVRPKSLRELSKSAEDLLsvdshnktvtitppkhgLKHSRHKNRVNGPRTFAFDECFAPsaP--------ESknlsgQED 82   Schizosacchar...
F4JX00        442 RIRPFLQGQNKKQTSIEYtgen----------gelVVANPLKQGKDTYRLFKFNKVFGP--E--------ST-----QEE 496  thale cress
P45962        251 RIRPQLASETDNQKPVVVide-----------mdnGVVHVSNTTGTRKTSAGADKVIPT--D--------FS-----QDQ 304  Caenorhabditi...
P91400        254 RVRPLIKSEADASSSAIEyp--------------aIDTIRINEGSKPGIVVKFEKVFTP--V--------FS-----QKE 304  Caenorhabditi...
Q9BVG8        451 RVRPVTKEDGEGPEATNAvtf-----------dadDDSIIHLLHKGKPVSFELDKVFSP--Q--------AS-----QQD 504  human
O08672        415 RLRPAEGQPSSLVSVEPG-----------------QGGTITTCYRGRQHCFRLDWVFPQ--D--------ASq---eEVF 464  house mouse
Q9LX99        148 RARPLFEDEGPSVIEFPGdc-------------tiCVNTSDDTLSNPKKDFEFDRVYGP--H--------VG-----QAA 199  thale cress
1SDM_A         12 RLRPLCEKEIIAKERNAIrs-------------vdEFTVEHLWKDDKAKQHMYDRVFDG--N--------AT-----QDD 63   potato
XP_006347819  103 RVRPFSPTDKQRTHQPISv----------------ESEKIVVRSGGSRKEFEFDKVFPQ--E--------SL-----QED 151  potato
1IA0_K         89 VYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQ---EkdQQGIIPQLCEDLFSRINDttnD-NMSYSVE-VSYM 163  house mouse
Q9UTL2         83 VYESTGPLLVKSILEGFNSCFITYGQKGTGKTYSVVG-L---Rg-QPGIIPHISESIFEEIDKlkkKsPNTTITVsISLA 157  Schizosacchar...
F4JX00        497 VFLDT-RPMIRSILDGYNVCIFAYGQTGSGKTYTMSGPsitsEe-DRGVNYRALNDLFHLTQSrqnS--VMYEVG-VQMV 571  thale cress
P45962        305 IFNEV-SPIITSCIDGYNVCIFAYGHTGSGKTYTMDG-P---Vt-MPGINQRAIMQLFETAKErtgD--IKYDIK-VAMM 375  Caenorhabditi...
P91400        305 VFAN-VEEFIRSSLHGYNVGLIAYGQTGSGKTHTMRGGN---Ge-EEGIIPRAAAFLFAESRKlesL-GWKFDFS-LSFL 377  Caenorhabditi...
Q9BVG8        505 VFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGT----Ae-NPGINQRALQLLFSEVQEkasD--WEYTIT-VSAA 575  human
O08672        465 RQLE---PAVLSCLQGYSVCIFTYGQTGTGKTYSMEGpP---Ed--PGIAPRALQLLFREMGTg---gHH--HVT-LSMV 530  house mouse
Q9LX99        200 LFSDV-QPFVQSALDGSNVSILSYGQTNAGKTYTMEGS----Nh-DRGLYARCFEELFDLANSdstS-TSRFSFS-LSVF 271  thale cress
1SDM_A         64 VFEDT-KYLVQSAVDGYNVCIFAYGQTGSGKTFTIYGA----Ds-NPGLTPRAMSELFRIMKKdsnK--FSFSLK-AYMV 134  potato
XP_006347819  152 VFAE-VEPIIRSALDGHNVCILAYGQTGTGKTYTMEGI----Te-SPGIIPRVLQELFNLSSLd---sSISFTFS-ISML 221  potato
1IA0_K        164 EIYCERVRDLLNPK-------NKGn---LRVRE-HPLLG-PYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSS 231  house mouse
Q9UTL2        158 EIIEETPYDLLQPNvn----sSHTpgetVFVQK-DSLTG-YHLHGLSEFEVGSAQEIDAFLRLAAKNIRTELSDISG-VR 230  Schizosacchar...
F4JX00        572 EIYNEQVRDLLSQD----------------------------VPDASMHSVRSTEDVLELMNIGLMNRTVGATTLNEKSS 623  thale cress
P45962        376 EIYNEKIRDLLNTS--------NTn---LAIRQ-TEEGR-SSIPGLEEVSVNSAEEVTETLARGRKNKAVAATEANIESS 442  Caenorhabditi...
P91400        378 EVYNNVAYDLLSDRa------------vVQLRL-NDQt--VSMIGLSEHTISNVSDVARLLRVADGGRKTAATKCNESSS 442  Caenorhabditi...
Q9BVG8        576 EIYNEVLRDLLGKEp-----qEKLe---IRLCP-DGS-GqLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSS 645  human
O08672        531 EIYNEAVRDLLATGpp---erLVVr-----QGP-AGQ-GgIQVAGLTHWDVPNLETLHQMLSLGRSNRATAATVMNQHSS 600  house mouse
Q9LX99        272 EIYNEQIRDLLSET--------QSn---LPNINmDLHES---VIELGQEKVDNPLEFLGVLKSAFLNRGNYKSKFNV--- 334  thale cress
1SDM_A        135 ELYQDTLVDLLLPKq------AKRl--kLDIKK-DSK-GmVSVENVTVVSISTYEELKTIIQRGSEQRHTTGTLMNEQSS 204  potato
XP_006347819  222 EVYLGSIRDLLAPRpssrkytASRc--nLNIQT-DSK-GsVEIDGLTEVEISNFTKAKWWYHKGRRVRSTSWTNVNETSS 297  potato
1IA0_K        232 RSHAVFNIIFTQKRHDae---tnITTekvSKISLVDLAGSERADSTG---------AKGTRLKEGANINKSLTTLGKVIS 299  house mouse
Q9UTL2        231 KGHSVFSLVVQQRIIDpktrhslkKA---SRLQIIDLASFSKGSQRN----------ESISSFESSSNNKSLSVLNRVIA 297  Schizosacchar...
F4JX00        624 RSHSVLSVHVRGVDVKte----svLR---GSLHLVDLAGSERVGRSE---------VTGERLKEAQHINKSLSALGDVIF 687  thale cress
P45962        443 RSHVIVRVLVSATNLItk----atTV---GRLNLVDLAGSERVSQTN---------ATGQLLKEAQAINKSLSELGNVVL 506  Caenorhabditi...
P91400        443 RSHAVYMWKITAHQPStg----isTS---CQLKLVDLAGSERAKESGv--------SGD-QFKEMTNINQSLSILQMCIS 506  Caenorhabditi...
Q9BVG8        646 RSHALLIVTVRGVDCStg----lrTT---GKLNLVDLAGSERVGKSG---------AEGSRLREAQHINKSLSALGDVIA 709  human
O08672        601 RSHALVTLTLRAAS-Pprpq------gitgTLHLVDLAGSERVWKAGvaspvqrdpNGARRLREAQAINRSLLALGGVMA 673  house mouse
Q9LX99        335 -THLIVSIHIYYSNTItg----enIY---SKLSLVDLAGSEGLIMENd---------SGDHVTDLLHVMNSISALGDVLS 397  thale cress
1SDM_A        205 RSHLIVSVIIESTNLQtq----aIAR---GKLSFVDLAGSERVKKSGs--------AGNQ-LKEAQSINKSLSALGDVIS 268  potato
XP_006347819  298 RSHCLTRISIYRYGDTlg---gkPEA---TKLWMVDLGGSERLLKTG---------ATGQTLDEGRAINLSLSALGDVIA 362  potato
1IA0_K        300 ALAEMd-SgpnknkkkkktDFIPYRDSVLTWLLRENLG-GNSRTAMVAALSPADINYDETLSTLRYADRAKQI 370  house mouse
Q9UTL2        298 ALTSKknD-----------VLIPYKDSVLTTLLQDALG-GNCRTIMLTCVSPCDF--DDTFSALRYSEAARRI 356  Schizosaccharomyces ...
F4JX00        688 ALAHK--N-----------PHVPYRNSKLTQVLQNSLG-GQAKTLMFVQINPDEDSYAETVSTLKFAERVSgv 746  thale cress
P45962        507 ALRQN--Q-----------KHIPFRNCQLTRILEDSLN-GDSKTLVIVHLSPDAKSLNESISSVNFAEKIGQV 565  Caenorhabditis elegans
P91400        507 QQRSQ--K-----------GHVSYRDSKLTQVLMDCLGrGNSKTMVVVNLNPCNEQATESKRSIEFASKMRSt 566  Caenorhabditis elegans
Q9BVG8        710 ALRSR--Q-----------GHVPFRNSKLTYLLQDSLS-GDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 768  human
O08672        674 ALRAR--R-----------PHVPFRDSQLTRLLQPALWa-GTTAVLLLQISTRAEDLGETICSLKFAERVGQV 732  house mouse
Q9LX99        398 SLTSG--K-----------DSIPYDNSILTRVLADSLG-GSSKTLMIVNICPSVQTLSETISCLNYAARARNT 456  thale cress
1SDM_A        269 ALSSG--N-----------QHIPYRNHKLTMLMSDSLG-GNAKTLMFVNISPAESNLDETHNSLTYASRVRSI 327  potato
XP_006347819  363 ALRRK--K-----------GHVPYRNSKLTQVLKDSLG-DKSKVLMVVHVSPYEEDVGETTCSCTFAKRARaa 421  potato
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