1V89,1U27,1X05,1PLS,4CKG,3FEH,2VRW,2LUL,4A6F,1BWN,1WI1,3HK0,1DRO,4XH9,5EFX


Conserved Protein Domain Family
PH

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pfam00169: PH 
Click on image for an interactive view with Cn3D
PH domain
PH stands for pleckstrin homology.
Statistics
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PSSM-Id: 333896
View PSSM: pfam00169
Aligned: 126 rows
Threshold Bit Score: 30.5831
Threshold Setting Gi: 357528764
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1V89_A          8 PIKMGWLK-----KQRSIVK---------NWQQRYFVLRaQQ-LYYYKDE-----------EDTK--------PQGCMYL 53
gi 257050981 2158 IVAQGKLL-----LQDTFLVtdqdagllpRCRERRIFLF-EQ-IVIFSEPldkkk--gfsmPGFL--------FKNSIKV 2220
gi 17371603   450 VIFMSQVM-----VQYGACE---------EKEERYLMLFsNV-LIMLSASpr--------mSGFI--------YQGKIPI 498
gi 50403776   480 VTYMSQVL-----IQCAGSE---------EKNERYLLLFpNV-LLMLSASpr--------mSGFI--------YQGKLPT 528
gi 52782735   387 LLCHGELR-----SKS-------------GHK-LYIFLF-QDiLVLTRPVtrnerhsyqvyRQPI--------PVQELVL 438
gi 121515     457 FVRQGSLIqvpmsEKGKINKgrlgslslkKEGERQCFLF-SKhLIICTRGsgs-------klHLT--------KNGVISL 520
gi 732235      36 LVGEGVLV-----KMCRK-----------KPKQRQFFLF-ND-ILVYGNIvi-------skKRYN--------KQRILRL 82
gi 341940631  474 LIHEGCLL------WKTATG---------RFKDVLLLLMtDV-LVFLQEKdqk-----yifTSLD--------KPSVVSL 524
4XH9_A        241 LLCHGELR-----SKSG--------------HKLYIFLFqDI-LVLTRPVtr--------nERHSyqvyrqpiPVQELVL 292
5EFX_A         35 LIHDGCLL-------WKTATg--------RFKDVLVLLMtDV-LVFLQEKdqk-----yifPTLD--------KPSVVSL 85
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1V89_A         54 PGCTIKEIAT--------NPEEAGKFVFEI-----IPASWdqnRmgqdSYVLMASSQAEMEEWVKFLRRV 110
gi 257050981 2221 SCLCLEEN------------VENDPCKFAL-----TSRTGdvvE----TFILHSSSPSVRQTWIHEINQI 2269
gi 17371603   499 AGTVVTRL----------DEIEGNDCTFEI-----TGNTV---E----RIVVHCNNNQDFQEWLEQLNRL 546
gi 50403776   529 TGMTITKL----------EDSENHRNAFEIsgs--------miE----RILVSCNNQQDLQEWVEHLQKQ 576
gi 52782735   439 EDLQDGDVRMggsfrgafSNSEKAKNIFRI-----RFHDPspaQ----SHTLQANDVFHKQQWFNCIRAA 499
gi 121515     521 IDCTLLDDPEnm----ddDGKGQEVDHLDFkiwvePKDsp--pF----TVILVASSRQEKAAWTSDIIQC 580
gi 732235      83 EGVQVEDL----------EDDGIEKHGWII-----KTPa----K----SFAVYAATETEKREWMLHIERC 129
gi 341940631  525 QNLIVRDI------------ANQAKGMFLI-----SSGPP---E----MYEVHAASRDDRTTWIRVIQQS 570
4XH9_A        293 EDLQDGDVRMggsfrgafSNSEKAKNIFRI-----RFHDPspaQ----SHTLQANDVFHKQQWFNCIRAA 353
5EFX_A         86 QNLIVRDIAN--------QEKG----MFLI--------SAappE----MYEVHTASRDDRSTWIRVIQQS 131
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