1V89,1U27,1X05,1PLS,4CKG,3FEH,2VRW,2LUL,4A6F,1BWN,1WI1,3HK0,1DRO,4XH9,6FSF,5EFX


Conserved Protein Domain Family
PH

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pfam00169: PH 
Click on image for an interactive view with Cn3D
PH domain
PH stands for pleckstrin homology.
Statistics
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Aligned: 127 rows
Threshold Bit Score: 31.3514
Threshold Setting Gi: 357528764
Created: 19-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1V89_A    8 PIKMGW--LK-----KQRSIVK---------NWQQRYFVLRaQQ-LYYYKDE------------EDTK--------PQGC 50   human
Q12802 2232 LVRDGSvfLK-----NAAG------------RLKEVQAVLLtDI-LVFLQEKdqky-----ifaSLDQ--------KSTV 2280 human
P28818  457 FVRQGS--LIqvpmsEKGKINKgrlgslslkKEGERQCFLF-SKhLIICTRGsgs--------klHLT--------KNGV 517  Norway rat
P34657   36 LVGEGV--LV-----KMCRK-----------KPKQRQFFLF-ND-ILVYGNIvi--------skKRYN--------KQRI 79   Caenorhabditis elegans
Q7Z628  387 LLCHGE--LR-----SKS-------------GHK-LYIFLF-QDiLVLTRPVtrnerh-syqvyRQPI--------PVQE 435  human
Q02384  443 FIMEGP--LT-----RIG-------------AKHERHIFLFdGL-MISCKPNhgqtrl-pgyssAEYR--------LKEK 492  house mouse
P26675  481 FIREDS--LS-----KLGSGKR---------IWSERKVFLFdGL-MVLCKANtkkqtpsagataYDYR--------LKEK 535  fruit fly
P54100  403 PKIDGE--LK-----ITSVERR---------SKTDRYAFLLdKA-LLICKRRg-----------DSYD--------LKAS 446  Norway rat
2VRW_B  234 PKIDGE--L------KITSVERr--------SKTDRYAFLLdKA-LLICKrr-----------gDSYD--------LKAS 277  house mouse
4XH9_A  241 LLCHGE--LR-----SKSG--------------HKLYIFLFqDI-LVLTRPVtr---------nERHSyqvyrqpiPVQE 289  human
1V89_A   51 MYLPGCTIKEIAT--------NP-EEAGKFVFEI-----IPASWDQn--RmgqdSYVLMASSQAEMEEWVKFLRRV 110  human
Q12802 2281 ISLKKLIVREV-------------AHEEKGLFLI-----SMGMTDP---E----MVEVHASSKEERNSWIQIIQDT 2331 human
P28818  518 ISLIDCTLLDDPEnm----ddDG-KGQEVDHLDFkiwvePKD--SPp--F----TVILVASSRQEKAAWTSDIIQC 580  Norway rat
P34657   80 LRLEGVQVEDL----------ED-DGIEKHGWII-----KTPa------K----SFAVYAATETEKREWMLHIERC 129  Caenorhabditis elegans
Q7Z628  436 LVLEDLQDGDVRMggsfrgafSN-SEKAKNIFRI-----RFHDPSPa--Q----SHTLQANDVFHKQQWFNCIRAA 499  human
Q02384  493 FVMRKIQICDK----------ED-ACEYRHAFEL-----VSK--DE---N----SVIFAAKSAEEKNNWMAALISL 543  house mouse
P26675  536 YFMRRVDINDR----------PD-SDDLKNSFEL----------APrmqP----PIVLTAKNAQHKHDWMADLLMV 586  fruit fly
P54100  447 VNLHSFQVRDDS---------SGeRDNKKWSHMF-----LLIEDQGa--Q----GYELFFKTRELKKKWMEQFEMA 502  Norway rat
2VRW_B  278 VNLHSFQVRDDSS--------GE-RDNKKWSHMF-----LLIEDQGa--Q----GYELFFKTRELKKKWMEQFEMA 333  house mouse
4XH9_A  290 LVLEDLQDGDVRMggsfrgafSN-SEKAKNIFRI-----RFHDPSPa--Q----SHTLQANDVFHKQQWFNCIRAA 353  human
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