1QK3,2E55


Conserved Protein Domain Family
Pribosyltran

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pfam00156: Pribosyltran 
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Phosphoribosyl transferase domain
This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7, Hypoxanthine-guanine-xanthine phosphoribosyl-transferase, Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10, Uracil phosphoribosyl-transferase EC:2.4.2.9, Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, at the very N-terminus of this domain is the P-Loop NTPase domain.
Statistics
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Aligned: 35 rows
Threshold Bit Score: 82.8598
Threshold Setting Gi: 123544842
Created: 19-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1QK3_A         47 KILLPGGLvkdRVEKLAYDIHRTyf-----geELHIICILKGSRGFFNLLIDYL-------ATiqkysgressvpPFFeh 114  Toxoplasma go...
P65833        106 SDLLSTPAilkNIGRIIAKSFMDq-------kIDAVMTVATKGVPLANAVANVL-------NV------------SFV-- 157  Streptococcus...
Q0CVT8        933 LNIAQQPNglaLCASLLQSHFRGdw-----nnVDMIACCEAGGFVFAPVLASRV-------DV------------PLA-- 986  Aspergillus t...
Q8G661         39 GAFDDGKKiaaLGAFYAEKISQAivhntiprnIDTVFGPAYKGIPLAVSTAIALtag-hnmTV------------GYT-- 103  Bifidobacteri...
Q4XNN5         75 TGFLNNAIssnIVSFLISNLILSkn-----lsFDYLFGASYKGIPIVTLTSHFLlntnkfhNV------------FYL-- 135  Plasmodium ch...
Q6A910         45 RVTLSDPQtrdLIADGLASLVRTnf-----hqVDVVAGTATAGIAHAALAADRL-------GA------------PMA-- 98   Cutibacterium...
Q9RX68         36 TTLLQHPRalmELGGLMSQKILDag-----lkPDFIVGPAMGGVTLAYEVARQL-------SE------------TLP-- 89   Deinococcus r...
Q0C3U2         36 ALVFSRPDlseKLCKALAARLAAdf-----gkIDVVAGPAVGGIIPGYELARHL-------GA------------RAI-- 89   Hyphomonas ne...
WP_012701547    7 AELSD------DIRSNLHRLHDRr--------IDLVVGIPRSGMIPAYMIALYL-------NL------------GCL-- 51   Azotobacter v...
XP_001598395   59 ASLLINQAsidVVDELSSFLSEKvap----fnPDVIIGLPTLGLTLAPIVARKLgl---krYI------------PLG-- 117  Sclerotinia s...
1QK3_A        115 YVRLKSYQNDNSTGQLTVLSD-------------------DLSIFRDKHVLIVEDIVDTGFTLTEFGE-RLKAVGPK--S 172  Toxoplasma go...
P65833        158 IVRRDLKITEGSTVSVNYVSGssgdri-------ekmflsKRSLKAGSRVLIVDDFLKGGGTVNGMIS-LLREFDSE--L 227  Streptococcus...
Q0CVT8        987 LIREEGKLPPPTVSVSRSASHisasatasklskrtrieisSETIPRGASVVIVDDVLATGNTLLAILR-LLEKVGVCtdR 1065 Aspergillus t...
Q8G661        104 FDRKEKKDHGDGGWMV------------------------GTPLTDGMKVLLVDDVMTAGTAVREVIPkLKAEANVE--V 157  Bifidobacteri...
Q4XNN5        136 YDRKEKKDYGDASVIIGNLEEnhig------------saqVEKKTDKKKVIVIDDVFSYGTALTDIFNkIKAFDYLE--I 201  Plasmodium ch...
Q6A910         99 YVRSVPKDHGRGNQI-------------------------EGRIPAHSKVIMVEDLISTGGSVLKAAQ-AVEREGST--V 150  Cutibacterium...
Q9RX68         90 DVRAIFAEKDGSGGMKLRE---------------------AFAVRPGETFVAVEDVLTTGGSLLRAVR-AVEGQGGQ--C 145  Deinococcus r...
Q0C3U2         90 FAERVDGQLQFRRGFS---------------------------IAAGERVLIAEDIVTTGLSFRETVE-ALAKLPGE--V 139  Hyphomonas ne...
WP_012701547   52 DLESFCRNESPANGGTRSPGKp------------------LARAWDARTVLLVDDSIASGKSMRAAVE-RLPEAFAG--K 110  Azotobacter v...
XP_001598395  118 YSRKFWYDDALSAAVSSITSPelglkn-------tyldphLLPLLIGKKCVIIDDAVSSGTTLKTTWD-LLERIGCE--I 187  Sclerotinia s...
1QK3_A        173 MRIATLV----EKRTDRSNSLKGDFVGFSIE--D--VWIVGCCYDF 210  Toxoplasma gondii RH
P65833        228 AGVAVFA----DNAQEEREKQFDYKSLLKVTniDvkNQAIDVevgn 269  Streptococcus pneumoniae R6
Q0CVT8       1066 IRIIVVAef-pDHHGRGLLRk---------------HGFGRVDIQS 1095 Aspergillus terreus NIH2624
Q8G661        158 VGLVLSV----DRMEKTKDSDMSAV--------KavEAEFGFPVLS 191  Bifidobacterium longum NCC2705
Q4XNN5        202 VACIVIL----NRNEHEINEKNEKIYFK-----DkfEQKHNIPVYS 238  Plasmodium chabaudi
Q6A910        151 VGVLALFsyelEKGHRAFEKAGVPLYTLSNYpiLieVAAESGRITS 196  Cutibacterium acnes KPA171202
Q9RX68        146 IGLCCII----DRRQQTGPLSGYPLMSLKELyfDtyASHEVPGWLA 187  Deinococcus radiodurans R1
Q0C3U2        140 VGGACII----DRSGGRADVGCKLISLAQVNfpDyaPDDLPPELQK 181  Hyphomonas neptunium ATCC 15444
WP_012701547  111 VIRMAVY----SSSMAPAEVDLHFRHLGWPRlfEwnIYHHGILVRT 152  Azotobacter vinelandii
XP_001598395  188 VGCGVVM----RQGEKWMEKi------------GweRVGKLVHVLE 217  Sclerotinia sclerotiorum 1980 UF-70
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