1VYW,4Y72


Conserved Protein Domain Family
Cyclin_N

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pfam00134: Cyclin_N 
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Cyclin, N-terminal domain
Cyclins regulate cyclin dependent kinases (CDKs). Cyclin-0 (CCNO) is a Uracil-DNA glycosylase that is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the N-terminal domain.
Statistics
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PSSM-Id: 333867
View PSSM: pfam00134
Aligned: 97 rows
Threshold Bit Score: 67.1548
Threshold Setting Gi: 75278850
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1VYW_B   14 DIHTYLREMEVKc--KPKVGYMK-KQp---DITN-SMRAILVDWLVE-VGEEYKLQNETLHLAVNYIDRFLSSM-S---V 81   human
P24867   19 DIIKFLTDTTLRvvpS--SNYPT-PPgspgEKHL-TRLPSLMTFITR-LVRYTNVYTPTLLTAACYLNKLKRILpRdatG 93   Saccharomyces cerev...
P25693   18 EMVQYLASTTASiikIKKTNSMI-DIal--------paPPLTKFINR-LIKHSNVQTPTLMATSVYLAKLRSIIpSnvyG 87   Saccharomyces cerev...
Q12477   19 EMIQFLATSTASiikIRENNNPI-QGcr---------pPDLSIFIKN-VVIQSNVQTPTLMATSVYLNKLKSVIpKnvyG 87   Saccharomyces cerev...
Q9VKF0  205 DIFDEKLHPLTHd--QVPDNYDT--------HNP--EHRQIYKFVRT-LFNAAQLTAECAIITLVYLERLLTYAeLd--V 269  fruit fly
O80513   22 ERVAESNDLTRRv-aTQSQRVSV-FHglsrP------TITIQSYLER-IFKYANCSPSCFVVAYVYLDRFTHRQps-lpI 91   thale cress
Q56YF8   28 IIPWFFSREEIEr--NSPSRRDG-IDl---KTET-RLRDSYCTFLEI-LGERLKVPQVTIATAIFFCHRFFLRQ-S---H 95   thale cress
O96433   42 DKIWYFSNDQLA---NSPSRRCG-IKg---DDEL-QYRQMTAYLIQE-MGQRLQVSQLCINTAIVYMHRFYAFHsF---T 109  fruit fly
P47821   45 DSKQNGIEQSITkniPITHRDLH--------YDKdYNLRIYCYFLIMkLGRRLNIRQYALATAHIYLSRFLIKAs----V 112  Saccharomyces cerev...
P93411    4 NFWTSSHCKQLLdqeDVDKVPQAdSDrg-iTLEEfRLVKIHMSFHIWrLAQQVKVRQRVIATAVTYFRRVYTRK-S---M 78   Japanese rice
1VYW_B   82 LRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYIT-----DD-TYT---------------KKQVLRMEHLVLKVLTFDLA 140  human
P24867   94 LPSTIHRIFLACLILSAKFHNDSSPLNKHWARYT-----DG-LFT---------------LEDINLMERQLLQLLNWDLR 152  Saccharomyces cerev...
P25693   88 IETTRHRIFLGCLILAAKTLNDSSPLNKHWAEYT-----DG-LLI---------------LREVNTIERELLEYFDWDVT 146  Saccharomyces cerev...
Q12477   88 INTTRHRIFLGCLILAAKTLNDSSPWNKHWTTYT-----EG-LLR---------------IREVNTIERELLEYLNWDVR 146  Saccharomyces cerev...
Q9VKF0  270 GPCNWKRMVLGAILLASKVWDDQAVWNVDYCQILk----DI---T---------------VEDMNELERQFLELLQFNIN 327  fruit fly
O80513   92 NSFNVHRLLITSVMVAAKFLDDLYYNNAYYAKV-------G-GIS---------------TKEMNFLELDFLFGLGFELN 148  thale cress
Q56YF8   96 AKNDRQTIATVCMLLAGKVEET-PVTLEDVIIASy----ER-IHKkdlagaqrkevydqqKELVLIGEELVLSTLNFDLC 169  thale cress
O96433  110 -HFHRNSMASASLFLAAKVEEQ-PRKLEHVIRAAn----KC-LPPtteqn------yaelAQELVFNENVLLQTLGFDVA 176  fruit fly
P47821  113 REINLYMLVTTCVYLACKVEEC-PQYIRTLVSEAr---tLWpEFIpp------------dPTKVTEFEFYLLEELESYLI 176  Saccharomyces cerev...
P93411   79 TEYDPRLVAPTCLYLASKVEESTVQARLLVFYIKkmcasDE-KYRf-------------eIKDILEMEMKLLEALDYYLV 144  Japanese rice
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