Conserved Protein Domain Family
zf-CCHC

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pfam00098: zf-CCHC 
Zinc knuckle
The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.
Statistics
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PSSM-Id: 306581
View PSSM: pfam00098
Aligned: 81 rows
Threshold Bit Score: 27.8689
Threshold Setting Gi: 50401851
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P40507  173 VFCYNCGNAGHFGDDCAE 190  Saccharomyces cerevisiae S288c
O92815  501 NTCFFCKQPGHWKADCPN 518  Walleye dermal sarcoma virus
P34689  242 MKCFNCKGEGHRSAECPE 259  Caenorhabditis elegans
O01836  202 NTCFNCKKYGHRATECSA 219  Caenorhabditis elegans
P34689  158 NNCFNCQQPGHRSSDCPE 175  Caenorhabditis elegans
P53849   65 QRCFNCNQTGHISRECPE 82   Saccharomyces cerevisiae S288c
Q6ZN17  149 KKCHYCQSIMHMVANCPH 166  human
O16635  311 PYCYKCKVVGHVSKDCPQ 328  Caenorhabditis elegans
Q12476   61 PKCNNCSQRGHLKKDCPH 78   Saccharomyces cerevisiae S288c
P40507  112 IICTNCNANGHYKSQCPH 129  Saccharomyces cerevisiae S288c
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