5FM1,1W5F,3ZID,2R6R


Conserved Protein Domain Family
Tubulin

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pfam00091: Tubulin 
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Tubulin/FtsZ family, GTPase domain
This family includes the tubulin alpha, beta and gamma chains, as well as the bacterial FtsZ family of proteins. Members of this family are involved in polymer formation. FtsZ is the polymer-forming protein of bacterial cell division. It is part of a ring in the middle of the dividing cell that is required for constriction of cell membrane and cell envelope to yield two daughter cells. FtsZ and tubulin are GTPases. FtsZ can polymerize into tubes, sheets, and rings in vitro and is ubiquitous in eubacteria and archaea. Tubulin is the major component of microtubules.
Statistics
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PSSM-Id: 333832
View PSSM: pfam00091
Aligned: 92 rows
Threshold Bit Score: 64.1601
Threshold Setting Gi: 489601209
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5FM1_C         4 EIITLQAGQCGNHVGKFLWSqlakEhAIgtdglsqlpdssterdddtkpffreNSrNKFTpr-aiMMDSEPSVIADVENT 82
gi 122053118   2 ELLWLNFGQCGLQIADTYWTnlanNfTKnfsengshtsfy--ttgkdvgidvkKPkLSSLkprclVIDTETITSDEILIN 79
gi 124443019   3 QLITIHIGGAGSNIGSKLWY------NLsqhrqed-----------lssifqeNShQSYKpr-siFVNTIDDQVPKYDEP 64
gi 124443014   3 SAIHLHIGGAGVMIGNELWKlyqkEqTEtnvks----------------yiynENeTNYFpl-tlFMDLDDRMVNEVKKN 65
gi 124443023   3 SALHIHVGGAGIKMGDMLWKlyekEyNEttqkn----------------yiydEFeGNHYpq-afFVDTDDRMIHEVQRN 65
gi 124443026   3 SAFHIHIGGAGVMMGDMLWKlyekEhNEttlkn----------------yvyqQVdGHSHpl-tlFADLDDRMISEVQRN 65
gi 74892619    3 EVLTIEVGQAGIQLGNAIWEqycaEhAIdnggkrketss---kddsfkvffeeTGsGQFVpr-nlAVDLEPNVIDDVKNG 78
gi 121966202   3 EIISIHIGQSGIQVGNSCWElfclEhQIqpdckiiqnqk---nedlktnffseTQsGQFVpr-svYLDLDSNSIDEVKVG 78
gi 124443025   3 EIITIQVGQGGIQVGNACWElfclEhQIqpngqminqqvi-ekddalrtffseSDhQKLVpr-svLLDLEPTLINQVKTG 80
gi 74923837    3 EVISIHVGQGGIQLGDSCWEqlclEhGIqpnglmqreisn-qedsefykfyseNSkGNFVpr-slFIDSESEAISKVKDG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5FM1_C        83 frgf-fdpRNTWVASDGAsaGNSWANGY-DiGTRNQDDILNKIDKEIDSTDNfegFQLLHSVAGGTGSGLGSNLLEALCD 160
gi 122053118  80 skhslltkDNVLTDNGSH--GGNFMTVFnNlGQKYWKSIQRYVFNMMEKCDHfeyFNLTLGVGGSSGSALGAYTAQMLSQ 157
gi 124443019  65 qf----spNQFFYTKEDT--GNIYTVGHyCvAKDLIPKIQDEIRRQVENCDHfsgFLFTHSISGGFGSGYTTLLSSLLKN 138
gi 124443014  66 klin-yktNSFVTGKEDA--ANNYCRAHyTiGKEIVDKCLDNIRKQVESVDRidqFIITSALSGGTGSGFTSLLLERLSV 142
gi 124443023  66 qsvk-fkkHSFFHGTED---ASTFARGLcTiGGGIEQQALDCIQKQIETMDRldeFVITSSISGGTGSGFLSNLVSLLKI 141
gi 124443026  66 kqiq-fkkNSFLYGKEEA--SNIYSRGCyTiGKEIIDKGLDQIRKQIETMDRldqFVITTSIMGGTGSGFSTLLLQRLEV 142
gi 74892619   79 pfaamfhpEFLVHGKEDA--ANNFARGHyTiGKQIIDKVNDRLRKLVDNCDNvmgFVIGHSVGGGTGSGLGALILERLAV 156
gi 121966202  79 sqkqlfnhEFLVSKNDEK--ANTFARGNyQvSSEFIEFCLDKVRRLTESCQNlqgFLIYNSAGGGTGSGFGSLLTKKIKQ 156
gi 124443025  81 kfkemfkpEQFVSGKGGA--AHNFGRGHySiGREYIDICLERIRKIVDNCSSfqgFMMLNSVGGGTGSGLGTLLLEKLSV 158
gi 74923837   81 kyrelfsqNSFIYGKEDA--SNNFARGYyQiGKEYIDVSLERVRKLAEDCQSpqgILLFNSVGGGTGSGLGTLLLERLQE 158
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
5FM1_C       161 Ry-pKK-ILTTYSVFPA-RSsEVVVQSYNTILALRRLIEDSDATVVFDNASLLNISG 214
gi 122053118 158 Ly-pKIpIITNIVDDEN----TSPVASYNTLFSLSVLQEHSTMIIPFSNNNIIESIK 209
gi 124443019 139 Ey-qKS-MSFSFCLMPSpNYrNNVIESYNSIMSLNSMVEAFDGVILLQNEAIYQIIE 193
gi 124443014 143 EygaKV-DKNAFLIYPSkEIsNNTVDAFNAVLATHVTIEHCDSVVMLDNESMYKSID 198
gi 124443023 142 YyrkV--RCNGFIIFPSsKIsNNVVAIYNAVLSMENLMYSFNSITMFDNESMYNFID 196
gi 124443026 143 DyknKV-KTNGFIIFPSsGMsNNILGIYNAMFSIQMTRNHFHSITMFDNQSMYNVID 198
gi 74892619  157 Dy-rKK-PKVGFEIYPSpNLsTCVVEPYNALLATHWLLDHTEVSLLLDNEAIYGICQ 211
gi 121966202 157 Ny-nKK-SVLGFTIYPSdKTqTNEFEPYNSVLYSQNLIENGDVNLVFDNEAIYDICN 211
gi 124443025 159 Dy-cKK-SRLSITIYPSpETsEAMVEPYNSIFATSSLLEHSEVCIAMDNQALYDICK 213
gi 74923837  159 Dy-lKQ-IRIGINIYPYpNNdTAIIESYNAILATQYLQKFADVCILFDNQAVYGICN 213
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