2YNF,4OL8


Conserved Protein Domain Family
RVT_1

?
pfam00078: RVT_1 
Click on image for an interactive view with Cn3D
Reverse transcriptase (RNA-dependent DNA polymerase)
A reverse transcriptase gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. Reverse transcriptases occur in a variety of mobile elements, including retrotransposons, retroviruses, group II introns, bacterial msDNAs, hepadnaviruses, and caulimoviruses.
Statistics
?
Aligned: 71 rows
Threshold Bit Score: 111.61
Threshold Setting Gi: 431350424
Created: 18-Apr-2019
Updated: 18-Jul-2019
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2YNF_A   66 IKKKD--------STKWRKL----VDFRELNKRTQD------------FWEVQLGIPHPAG------------------L 103  HIV-1 M:B_HXB2R
O01419  502 IPKEGrpr---dqPSGYRPIvvlsEAGKLLERVVAGrlvrhlenvgpnLADSQYGFRRGRStldavqrvr-dlsdqacsR 577  domestic silkworm
O18558  472 IPKGGras--yeeAKSFRPIsltsFLLKCLERIIDHhirdvy-lanmpLHVNQHAYQSGKStvtllhkvv-ydiekafaQ 547  yellow fever mosquito
P21328  502 IHKTGktp---tdVDSYRPTsllpSLGKIMERLILNrlltck-dvtkaIPKFQFGFRLQHGtpeqlhrvv-nfaleameN 576  fruit fly
Q04135  496 IPKPGkdk---tqPSSYRPIslltCLSKLFEKMLLLrisphl-rinntLPTHQFGFREKHGtieqvnrit-seirtafeH 570  fruit fly
O96546  526 IHKPGkrr---tePSSYRPIsllrGLGKIYERIVLSrlrtfa-eannlVPDAQFGFRAKHScvqqvhrlv-eytssqfiM 600  gypsy moth
Q93137  515 KPKND--------PTSYRPIsllmSLGKLYERLLYKrlrdfv-sskgiLIDEQFGFRTNHScvqqvhrltehilvglnrP 585  domestic silkworm
Q07995  509 IPKHGkpa---seLSSYRPIsllsSISKILERVLLNrindhl-ednniIPNQQCGFRTGRStshqlikvi-ksakenlnN 583  Chironomus thummi
Q01379  505 LKKPGksaaqqklAGAWRPIsllsNVGKILEALVAKrltqaa-eefnlLPEGQMGNRAGRStefavrvvt-davhtawkL 582  Neurospora crassa
Q9YGS2  573 LLKKPsld--pdvLANYRPIsnlpFISKVLEKVVVTqllehl-qrnslFEMFQSGFRAHHStetallkvt-ndlliasdH 648  torafugu
2YNF_A  104 KKK-KSVTVLDVGDAYFSVPLDEDFR-KYTAFTIPSI---NNET---------------PGIRYQYNVLPQGWKGSPAIF 163  HIV-1 M:B_HXB2R
O01419  578 GGV-LLAVSIDISNAFNTVPWSTILE-SLRFHRVPTGlrnLIEDylagravv-fperrgwGHKAVSCGVPQGSVLGPLLW 654  domestic silkworm
O18558  548 KQS-CLGVFLDIEGAFDNVSFDAILE-AARNHGLPTMitnWIHQmlknrhl-fstlrqaAIRKLSVCGCPQGGVLSPLLW 624  yellow fever mosquito
P21328  577 KEY-AVGAFLDIQQAFDRVWHPGLLY-KAKRLFPPQLy-lVVKSfleertfhvsvdgykSSIKPIAAGVPQGSVLGPTLY 653  fruit fly
Q04135  571 REY-CTAIFLDVAQAFDRVWLDGLLF-KIIK-LLPQNthkLLKSylynrvfaircdtstSRDCAIEAGVPQGSVLGPILY 647  fruit fly
O96546  601 NRY-TGVLFLDVAKAFDKVWHEGLIY-KLYLLKIPHYlihIIHDylshrsfryrvegtlSTSHPIKAGVPQGSVLSPFLF 678  gypsy moth
Q93137  586 KPLyTGALFFDVAKAFDKVWHNGLIF-KLFNMGVPDSlvlIIRDflsnrsfryrvegtrSSPRPLTAGVPQGSVLSPLLF 664  domestic silkworm
Q07995  584 KKS-TGMIFLDVEKAFDRVWHPGLLY-KMLKLRFPLPlikTVRSflsersfavfikgqfsEIKVIKFGVPQGAVLSPTLY 661  Chironomus thummi
Q01379  583 GAV-TSLMLLDLKGAFDRVNHRWLLH-TLWEMQLPTWiirWVASfvagrrgslffddetSRPYAITAGVPQGSPLSPILF 660  Neurospora crassa
Q9YGS2  649 GLV-SMLVLLDLSAAFDTVDHSILLQrLEHVIGIKGTaldWFRSylsdryqfahvhgvpsSYSRVSHGVPQGSVLGPILF 727  torafugu
2YNF_A  164 QSSMTKILEPFRKQnp---dIVIYQYMDDLLVGSDlE-IGQ------HRTKIEELRQHLLRWGLTTPDKKHQ-------- 225  HIV-1 M:B_HXB2R
O01419  655 DVGFDWVLRGANLRg-----VQVICYADDTLVTAR-GdDYRsas-ilAAAAVATVVARIRKLGLEVALHKSEavcfhpar 727  domestic silkworm
O18558  625 NLVADTLLRQLNNCg-----FPTYGFADEYLALIV-G-MCIstlfdlMQSALQVVESWCRQYGLSVNPNKTSivlfterr 697  yellow fever mosquito
P21328  654 SVFASDMPTHTPVTevdeedVLIATYADDTAVLTK-S-KSIlaatsgLQEYLDAFQQWAENWNVRINAEKCAnvtfanrt 731  fruit fly
Q04135  648 TLYTADFPIDYNL--------TTSTFADDTAILSR-S-KCPikatalLSRHLTSVERWLADWRISINVQKCKqvtftlnk 717  fruit fly
O96546  679 TLYTSDMPKFNRV--------HKALYADDTALFCA-G-RSPttvartLQTAVTALANWFRNWRLEINPEKSQavmftrrt 748  gypsy moth
Q93137  665 SLFVNDIPRSPPT--------HLALFADDTTVYYS-S-RNKsliakkLQSAALALGQWFRKWRIDINPAKSTavlfqrgs 734  domestic silkworm
Q07995  662 NIFTYDVVRETTN--------NIGLFADDTALYHS-AeNSAdiv-thLQHTGRKVQQYMNKWKINLNKQKTQalfitnrh 731  Chironomus thummi
Q01379  661 ILFITPLYRKLATIp----nTITVGFADDTNVVAV-A-RTTeencrtLQAAWEVCSEWAGARGMEFEATKTElmhftrtr 734  Neurospora crassa
Q9YGS2  728 TLYMLPLGNIIRQHg-----INFHCYADDTQLYLS-MkPEEteklvkLQTCLKDIKSWMSSNFLLLNPGKTEvmvfgpep 801  torafugu
2YNF_A  226 -------------------------KEPPFLWMGYEL 237  HIV-1 M:B_HXB2R
O01419  728 kgppp--------gasitiggtaiaVRSQLKYLGLVL 756  domestic silkworm
O18558  698 nrdg---------irplrlfgteinVTDQVKYVGVIL 725  yellow fever mosquito
P21328  732 gsc-----------pgvslngrlirHHQAYKYLGITL 757  fruit fly
Q04135  718 qtc-----------pplvlnnicipQADEVTYLGVHL 743  fruit fly
O96546  749 arsysi-----dsipplkifnkpvtWTRQAKYLGVTL 780  gypsy moth
Q93137  735 strissrirrrnltppitlfrqpipWARKVKYLGVTL 771  domestic silkworm
Q07995  732 srqlp--------gnnikflnenikWETEAKYLGMVI 760  Chironomus thummi
Q01379  735 aprt----------etlqlgdtvlqPTESTRFLGVWL 761  Neurospora crassa
Q9YGS2  802 lrdrl--------dhmitldgisltSSLSVRNLGVTF 830  torafugu
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap