5O91,4UY9,3BI6,4AGU,5N4Z,6HHJ,3UZT


Conserved Protein Domain Family
Pkinase

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pfam00069: Pkinase 
Click on image for an interactive view with Cn3D
Protein kinase domain
Statistics
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PSSM-Id: 395022
View PSSM: pfam00069
Aligned: 38 rows
Threshold Bit Score: 152.398
Threshold Setting Gi: 125256
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5O91_A  30 YSILKQIGSGGSSKVFQVLN-EKKQIYAIKYVNLEEADNQTL------DSYRNEIAYLNKLQqhSDKIIRLYDYEIT--- 99   human
P32490 221 IETLGILGEGAGGSVSKCKLkNGSKIFALKVINTLNTDPEYQ------KQIFRELQFNRSFQ--SEYIVRYYGMFTDd-e 291  Saccharomyces cerevi...
P06784 191 LVQLGKIGAGNSGTVVKALHvPDSKIVAKKTIPVEQNNSTII------NQLVRELSIVKNVKp-HENIITFYGAYYNqhi 263  Saccharomyces cerevi...
P10506  66 LEVVRHLGEGNGGAVSLVK--HRNIFMARKTVYVGSDSKLQ-------KQILRELGVLHHCR--SPYIVGFYGAFQY--- 131  Schizosaccharomyces ...
4UY9_A  11 LTLEEIIGIGGFGKVYRAF--WIGDEVAVKAARHDPDEDISQt----iENVRQEAKLFAMLK--HPNIIALRGVCLK--- 79   human
P17801 534 RKFKVELGRGESGTVYKGVl-EDDRHVAVKKLENVRQGK---------EVFQAELSVIGRIN--HMNLVRIWGFCSE--- 598  Zea mays
Q03497 620 YANLVKIGQGASGGVYTAYEiGTNVSVAIKQMNLEKQPKKEL--------IINEILVMKGSK--HPNIVNFIDSYVL--- 686  Saccharomyces cerevi...
P27636  25 YHLKQVIGRGSYGVVYKAINkHTDQVVAIKEVVYENDEELND--------IMAEISLLKNLN--HNNIVKYHGFIRK--- 91   Saccharomyces cerevi...
P28829 394 WIRGALIGSGSFGQVYLGMNaSSGELMAVKQVILDSVSESKDrhakllDALAGEIALLQELS--HEHIVQYLGSNLN--- 468  Schizosaccharomyces ...
P23647   4 YAVSSLVGQGSFGCVYKATRkDDSKVVAIKVISKRGRATKEL------KNLRRECDIQARLK--HPHVIEMIESFES--- 72   fruit fly
5O91_A 100 DQYIYMVMEWGNID-----LNSWLKkk------ksIDPW-------ERK-SYWKNMLEAVHtihqhgivhsdlkpanfl- 159  human
P32490 292 NSSIYIAMEYMGGRsldaiYKNLLErg------grISEK-------VLG-KIAEAVLRGLSylhekkvihrdikpqnill 357  Saccharomyces cerevi...
P06784 264 NNEIIILMEYSDCGs----LDKILSvykrfvqrgtVSSKktwfnelTIS-KIAYGVLNGLDhlyrqykiihrdikpsnvl 338  Saccharomyces cerevi...
P10506 132 KNNISLCMEYMDCGs----LDAILReg------gpIPLD-------ILG-KIINSMVKGLIylynvlhiihrdlkpsnvv 193  Schizosaccharomyces ...
4UY9_A  80 EPNLCLVMEFARGGp----LNRVLSgk-------rIPPD-------ILV-NWAVQIARGMNylhdeaivpiihrdlkssn 140  human
P17801 599 GSHRLLVSEYVENGs----LANIL-----------FSEGgnilldwEGRfNIALGVAKGLAylhheclewvihcdvkpen 663  Zea mays
Q03497 687 KGDLWVIMEYMEGGs----LTDVVth-------ciLTEG-------QIG-AVCRETLSGLEflhskgvlhrdiksdnill 747  Saccharomyces cerevi...
P27636  92 SYELYILLEYCANGs----LRRLISrss-----tgLSEN-------ESK-TYVTQTLLGLKylhgegvihrdikaanill 154  Saccharomyces cerevi...
P28829 469 SDHLNIFLEYVPGGs----VAGLLTmy------gsFEET-------LVK-NFIKQTLKGLEylhsrgivhrdikganilv 530  Schizosaccharomyces ...
P23647  73 KTDLFVVTEFALMD-----LHRYLSyn------gaMGEE-------PAR-RVTGHLVSALYylhsnrilhrdlkpqnvll 133  fruit fly
5O91_A 160 -----------ivdgmlklidfgianqmqPDTTsv----vKDSQVGTVNYMPPEAIkdmsssrengKSKSKiSPKSDVWS 224  human
P32490 358 -----------nengqvklcdfgvsgeavNSL--------ATTFTGTSFYMAPERI----------QGQPY-SVTSDVWS 407  Saccharomyces cerevi...
P06784 339 ----------inskgqiklcdfgvskkliNSI--------ADTFVGTSTYMSPERI----------QGNVY-SIKGDVWS 389  Saccharomyces cerevi...
P10506 194 ----------vnsrgeiklcdfgvsgelvNSV--------AQTFVGTSTYMSPERI----------RGGKY-TVKSDIWS 244  Schizosaccharomyces ...
4UY9_A 141 ililqkvengdlsnkilkitdfglarewhRTT--------KMSAAGTYAWMAPEVI----------RASMF-SKGSDVWS 201  human
P17801 664 i--------lldqafepkitdfglvkllnRGGStq----nVSHVRGTLGYIAPEWV----------SSLPI-TAKVDVYS 720  Zea mays
Q03497 748 -----------smegdikltdfgfcaqinELNLk------RTTMVGTPYWMAPEVV----------SRKEY-GPKVDIWS 799  Saccharomyces cerevi...
P27636 155 -----------sadntvkladfgvstivnSS---------ALTLAGTLNWMAPEIL----------GNRGA-STLSDIWS 203  Saccharomyces cerevi...
P28829 531 -----------dnkgkikisdfgiskkleLNSTstktggaRPSFQGSSFWMAPEVV----------KQTMH-TEKTDIWS 588  Schizosaccharomyces ...
P23647 134 -----------dknmhaklcdfglarnmtLGTHv------LTSIKGTPLYMAPELL----------AEQPY-DHHADMWS 185  fruit fly
5O91_A 225 LGCILYYMTYGKTPFQqiiNQIsklhAIID----------------------PnheiefpdIPEKDLQDVLKCCLKRDPK 282  human
P32490 408 LGLTILEVANGKFPCS----SEkmaaNIAPfellmwiltftpelkdepesniI---------WSPSFKSFIDYCLKKDSR 474  Saccharomyces cerevi...
P06784 390 LGLMIIELVTGEFPLGghnDTPdgilDLLQrivneps---------prlpkdR--------IYSKEMTDFVNRCCIKNER 452  Saccharomyces cerevi...
P10506 245 LGISIIELATQELPWSf--------sNIDDsigildllhci----------vqeepprlpssFPEDLRLFVDACLHKDPT 306  Schizosaccharomyces ...
4UY9_A 202 YGVLLWELLTGEVPFRgidGLAvaygVAMNklalp-----------------------ipstcPEPFAKLMEDCWNPDPH 258  human
P17801 721 YGVVLLELLTGTRVSElvgGTDevhsMLRKlvrmlsaklegeeqswidgyldsklnrpvnyvqARTLIKLAVSCLEEDRS 800  Zea mays
Q03497 800 LGIMIIEMIEGEPPYL------------NEtplralyliatn----------gtpklkepenlSSSLKKFLDWCLCVEPE 857  Saccharomyces cerevi...
P27636 204 LGATVVEMLTKNPPYHnltDANiyyaVENDtyyp-------------------------pssfSEPLKDFLSKCFVKNMY 258  Saccharomyces cerevi...
P28829 589 LGCLVIEMLTSKHPYP----------NCDQmqaifrigen--------------ilpefpsniSSSAIDFLEKTFAIDCN 644  Schizosaccharomyces ...
P23647 186 LGCIAYESMAGQPPFCassILHlvkmIKHEdvkw-------------------------pstlTSECRSFLQGLLEKDPG 240  fruit fly
5O91_A 283 QRISIPELLAHPYV 296  human
P32490 475 ERPSPRQMINHPWI 488  Saccharomyces cerevisiae S288C
P06784 453 ERSSIHELLHHDLI 466  Saccharomyces cerevisiae S288C
P10506 307 LRASPQQLCAMPYF 320  Schizosaccharomyces pombe 972h-
4UY9_A 259 SRPSFTNILDQ--L 270  human
P17801 801 KRPTMEHAVQtlls 814  Zea mays
Q03497 858 DRASATELLHDEYI 871  Saccharomyces cerevisiae S288C
P27636 259 KRPTADQLLKHVWI 272  Saccharomyces cerevisiae S288C
P28829 645 LRPTASELLSHPFV 658  Schizosaccharomyces pombe 972h-
P23647 241 LRISWTQLLCHPFV 254  fruit fly
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