4AGU


Conserved Protein Domain Family
Pkinase

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pfam00069: Pkinase 
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Protein kinase domain
Statistics
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Aligned: 39 rows
Threshold Bit Score: 234.055
Threshold Setting Gi: 125256
Created: 18-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4AGU_A    5 YEKIGKIGEGSYGVVFKCRnrDTGQIVAIKKFLESEDDPVIK------KIALREIRMLKQLK-HPNLVNLLEVFRR---K 74   human
P80192  144 LTLEEIIGIGGFGKVYRAF--WIGDEVAVKAARHDPDEDISQt----iENVRQEAKLFAMLK-HPNIIALRGVCLK---E 213  human
P17801  534 RKFKVELGRGESGTVYKGVl-EDDRHVAVKKLENVRQGK---------EVFQAELSVIGRIN-HMNLVRIWGFCSE---G 599  Zea mays
P27636   25 YHLKQVIGRGSYGVVYKAInkHTDQVVAIKEVVYENDEELND--------IMAEISLLKNLN-HNNIVKYHGFIRK---S 92   Saccharomyces cerev...
P28829  394 WIRGALIGSGSFGQVYLGMnaSSGELMAVKQVILDSVSESKDrhakllDALAGEIALLQELS-HEHIVQYLGSNLN---S 469  Schizosaccharomyces...
Q03497  620 YANLVKIGQGASGGVYTAYeiGTNVSVAIKQMNLEKQPKKEL--------IINEILVMKGSK-HPNIVNFIDSYVL---K 687  Saccharomyces cerev...
P32490  221 IETLGILGEGAGGSVSKCKlkNGSKIFALKVINTLNTDPEYQ------KQIFRELQFNRSFQ-SEYIVRYYGMFTDd-eN 292  Saccharomyces cerev...
P06784  191 LVQLGKIGAGNSGTVVKALhvPDSKIVAKKTIPVEQNNSTII------NQLVRELSIVKNVKpHENIITFYGAYYNqhiN 264  Saccharomyces cerev...
P10506   66 LEVVRHLGEGNGGAVSLVK--HRNIFMARKTVYVGSDSKLQ-------KQILRELGVLHHCR-SPYIVGFYGAFQY---K 132  Schizosaccharomyces...
P34208   10 YHIGREIGTGAFASVRLCYd-DNAKIYAVKFVNKKHATSCMNagv-waRRMASEIQLHKLCNgHKNIIHFYNTAEN---P 84   Schizosaccharomyces...
4AGU_A   75 RRLHLVFEYCDHTV----LHELDRyq------rgVPEH-------LVK-SITWQTLQAVNFCH-KHN---CIHRDVKPEN 132  human
P80192  214 PNLCLVMEFARGGP----LNRVLSgk-------rIPPD-------ILV-NWAVQIARGMNYLH-DEAivpIIHRDLKSSN 273  human
P17801  600 SHRLLVSEYVENGS----LANIL-----------FSEGgnilldwEGRfNIALGVAKGLAYLH-HEClewVIHCDVKPEN 663  Zea mays
P27636   93 YELYILLEYCANGS----LRRLISrss-----tgLSEN-------ESK-TYVTQTLLGLKYLH-GEG---VIHRDIKAAN 151  Saccharomyces cerev...
P28829  470 DHLNIFLEYVPGGS----VAGLLTmy------gsFEET-------LVK-NFIKQTLKGLEYLH-SRG---IVHRDIKGAN 527  Schizosaccharomyces...
Q03497  688 GDLWVIMEYMEGGS----LTDVVth-------ciLTEG-------QIG-AVCRETLSGLEFLH-SKG---VLHRDIKSDN 744  Saccharomyces cerev...
P32490  293 SSIYIAMEYMGGRSldaiYKNLLErg------grISEK-------VLG-KIAEAVLRGLSYLH-EKK---VIHRDIKPQN 354  Saccharomyces cerev...
P06784  265 NEIIILMEYSDCGS----LDKILSvykrfvqrgtVSSKktwfnelTIS-KIAYGVLNGLDHLYrQYK---IIHRDIKPSN 336  Saccharomyces cerev...
P10506  133 NNISLCMEYMDCGS----LDAILReg------gpIPLD-------ILG-KIINSMVKGLIYLYnVLH---IIHRDLKPSN 191  Schizosaccharomyces...
P34208   85 QWRWVVLEFAQGGD----LFDKIEpd------vgIDED-------VAQ-FYFAQLMEGISFMH-SKG---VAHRDLKPEN 142  Schizosaccharomyces...
4AGU_A  133 ILITkHSV--------IKLCDFGFARLLTGPSd------yYDDEVATRWYRSPELLvGDTQY-GPPVDVWAIGCVFAELL 197  human
P80192  274 ILILqKVEngdlsnkiLKITDFGLAREWHRTT--------KMSAAGTYAWMAPEVI-RASMF-SKGSDVWSYGVLLWELL 343  human
P17801  664 ILLD-QAFe-------PKITDFGLVKLLNRGGst----qnVSHVRGTLGYIAPEWV-SSLPI-TAKVDVYSYGVVLLELL 729  Zea mays
P27636  152 ILLS-ADNt-------VKLADFGVSTIVNSS---------ALTLAGTLNWMAPEIL-GNRGA-STLSDIWSLGATVVEML 212  Saccharomyces cerev...
P28829  528 ILVDnKGK--------IKISDFGISKKLELNStstktggaRPSFQGSSFWMAPEVV-KQTMH-TEKTDIWSLGCLVIEML 597  Schizosaccharomyces...
Q03497  745 ILLSmEGD--------IKLTDFGFCAQINELNl------kRTTMVGTPYWMAPEVV-SRKEY-GPKVDIWSLGIMIIEMI 808  Saccharomyces cerev...
P32490  355 ILLNeNGQ--------VKLCDFGVSGEAVNSL--------ATTFTGTSFYMAPERI-QGQPY-SVTSDVWSLGLTILEVA 416  Saccharomyces cerev...
P06784  337 VLINsKGQ--------IKLCDFGVSKKLINSI--------ADTFVGTSTYMSPERI-QGNVY-SIKGDVWSLGLMIIELV 398  Saccharomyces cerev...
P10506  192 VVVNsRGE--------IKLCDFGVSGELVNSV--------AQTFVGTSTYMSPERI-RGGKY-TVKSDIWSLGISIIELA 253  Schizosaccharomyces...
P34208  143 ILLDyNGN--------LKISDFGFASLFSYKGks----rlLNSPVGSPPYAAPEIT---QQYdGSKVDVWSCGIILFALL 207  Schizosaccharomyces...
4AGU_A  198 SGVPLWPgksDVDqlylIrktlgdlipRHQqvf-----------------stnQYfsgvKIPDPedmeplelkfPNI--- 257  human
P80192  344 TGEVPFRgidGLAvaygV---------AMN-----------------------KL----ALPIP----------STC--- 374  human
P17801  730 TGTRVSElvgGTDevhsM---------LRKlvrmlsaklegeeqswidgyldsKL----NRPVN----------YVQ--- 783  Zea mays
P27636  213 TKNPPYHnltDANiyyaV---------END-----------------------------TYYPP----------SSF--- 241  Saccharomyces cerev...
P28829  598 TSKHPYP----------N---------CDQmqaif--------------rigeNI----LPEFP----------SNI--- 627  Schizosaccharomyces...
Q03497  809 EGEPPYL---------------------NEtplraly----------liatngTP----KLKEP----------ENL--- 840  Saccharomyces cerev...
P32490  417 NGKFPCS----SEkmaaN---------IAPfellmw-----------iltftpEL----KDEPE----------SNIi-w 457  Saccharomyces cerev...
P06784  399 TGEFPLGghnDTPdgilD---------LLQri--------------------vNE----PSPRL----------PKDriy 435  Saccharomyces cerev...
P10506  254 TQELPWSf--------sN---------IDDsigild-----------llhcivQE----EPPRL----------PSSf-- 289  Schizosaccharomyces...
P34208  208 LGNTPWDeaisntgdy-----------------------------llykkqceRP----SYHPW----------NLL--- 241  Schizosaccharomyces...
4AGU_A  258 SYPALGLLKGCLHMDPTERLTCEQLLHHpyF 288  human
P80192  375 PEPFAKLMEDCWNPDPHSRPSFTNILDQ--L 403  human
P17801  784 ARTLIKLAVSCLEEDRSKRPTMEHAVQtlls 814  Zea mays
P27636  242 SEPLKDFLSKCFVKNMYKRPTADQLLKHvwI 272  Saccharomyces cerevisiae S288C
P28829  628 SSSAIDFLEKTFAIDCNLRPTASELLSHpfV 658  Schizosaccharomyces pombe 972h-
Q03497  841 SSSLKKFLDWCLCVEPEDRASATELLHDeyI 871  Saccharomyces cerevisiae S288C
P32490  458 SPSFKSFIDYCLKKDSRERPSPRQMINHpwI 488  Saccharomyces cerevisiae S288C
P06784  436 SKEMTDFVNRCCIKNERERSSIHELLHHdlI 466  Saccharomyces cerevisiae S288C
P10506  290 PEDLRLFVDACLHKDPTLRASPQQLCAMpyF 320  Schizosaccharomyces pombe 972h-
P34208  242 SPGAYSIITGMLRSDPFKRYSVKHVVQHpwL 272  Schizosaccharomyces pombe 972h-
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