2EC8,3WUW,3WUW,3WUW,2V5Y,4PBV,1ZVO,3QS7,3O4O,3MJG,4BFI,4BFI


Conserved Protein Domain Family
ig

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pfam00047: ig 
Click on image for an interactive view with Cn3D
Immunoglobulin domain
Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions. Examples include antibodies, the giant muscle kinase titin and receptor tyrosine kinases. Immunoglobulin-like domains may be involved in protein-protein and protein-ligand interactions.
Statistics
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PSSM-Id: 333796
View PSSM: pfam00047
Aligned: 46 rows
Threshold Bit Score: 40.2422
Threshold Setting Gi: 127511
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EC8_A        216 VSKASYLLREGEEFTVTCTIK--DVSSSVYSTWKRENSQTKLqekyNswhh-----------------gdfNYERQA--- 273
gi 124344      30 VANGTVTSLPGATVTLICPGK--EAAGNVTIHWVYSGSQNRE----Wt-------------------------tTGN--- 75
gi 342187134  127 PDKVTHTVNKGDTAVLSAHVH---KEKQTDVIWKNNGSYFNT----Ldw--------------------qeADDGRF--- 176
gi 120045      37 IEVESHSAHPGDLLQLRCRLR----DDVQSINWVRDGVQLPE----Nn----------------------rTRITGE--- 83
gi 129890      37 PPGPELVLNVSSTFVLTCSGS-------APVVWERMSQEPPQ----Emak-------------------aqDGTFSS--- 83
gi 20455514    21 KVTSLTACLVDQSLRLDCRHEn-TSSSPIQYEFSLTRETKKH----Vlfgtvg-------------vpehtYRSRTNfts 82
gi 127513     220 ITPSFVDIFISKSATLTCRVSnmVNADGLEVSWWKEKGGKLE----Talgkr--------------vlqsnGLYTVD--- 278
gi 129300      34 VVTQDERKLLHTTASLRCSLK--TTQEPLIVTWQKKKAVGPE----Nmvtyskah--------gvviqptyKDRINItel 99
3MJG_X          5 PPGPELVLNVSSTFVLTCSGS-------APVVWERMSQEPPQ----Emak-------------------aqDGTFSS--- 51
4BFI_B          4 VVTQDERKALHTTASLRCSLK--TSQEPLIVTWQKKKAVSPE----NmvtyskthgvviqpaykdrinvteLGLWNS--- 74
                          90       100       110
                  ....*....|....*....|....*....|....*...
2EC8_A        274 -----TLTISSARVNDSG-VFMCYANNTFGSANVTTTL 305
gi 124344      76 -----TLVLRDVQLSDTG-DYLCSLNDHLVGTVPLLVD 107
gi 342187134  177 -----QLQLQNVQPPSSG-IYSATYLEASPLGSAFFRL 208
gi 120045      84 -----EVEVRDAVPEDSG-LYACMTNSPSGSETTYFSV 115
gi 129890      84 -----VLTLTNLTGLDTG-EYFCTHNDSRGLETDERKR 115
gi 20455514    83 kynmkVLYLSAFTSKDEG-TYTCALHHSGHSPPISSQN 119
gi 127513     279 -----GVATVCASEWDGGdGYVCKVNHPDLLFPMEEKM 311
gi 129300     100 gllntSITFWNTTLDDEG-CYMCLFNMFGSGKVSGTAC 136
3MJG_X         52 -----VLTLTNLTGLDTG-EYFCTHNDSRGLETDERKr 83
4BFI_B         75 -----SITFWNTTLEDEG-CYMCLFNTFGSQKVSGTAC 106
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