1GD1


Conserved Protein Domain Family
Gp_dh_N

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pfam00044: Gp_dh_N 
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Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
GAPDH is a tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis. N-terminal domain is a Rossmann NAD(P) binding fold.
Statistics
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PSSM-Id: 333793
View PSSM: pfam00044
Aligned: 81 rows
Threshold Bit Score: 74.0493
Threshold Setting Gi: 21263632
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1GD1_O         2 VKVGINGFGRIGRNVFRAAL-----KNP-DIEVVAVND-L-TDANTLAHLLKYDSV--------HGRLDAEVSVN--GNN 63  Geobacillus ste...
Q7U825         1 MRIGINGFGRIGRLVFRALW-----GRP-GIELVHVNDpA-GDAATAAHLLEFDSV--------HGRWDRGISSD--ADG 63  Synechococcus s...
P58559         3 VRVGINGFGRMGRLALRAAW-----DWP-ELEFVHINEiK-GGAVAAAHLLKFDSV--------HGRWTPEVEAE--GER 65  Nostoc sp. PCC ...
Q7V1Y2         1 MKIGINGFGRIGRLVFRALW-----DRA-DTEITHINEmA-GDSNAAAHLLEFDSV--------HGRWVKDIKVK--EEE 63  Prochlorococcus...
Q6AS43         1 MKLGINGLGRIGKLSLWHHVa----HENfSEVVVNIGReVgGGLHDLASSIERDSTfgnlaaylHGCHGGRVIEElnEAA 76  Desulfotalea ps...
Q6F9D5       131 KDVVLYGFGRIGRILARLIIsqsgmGRGlGLKAIVVRKsSdGDLAKRASLLRRDSI--------HGSFDGTISIDeeNEA 202 Acinetobacter s...
Q8EEN1       127 RDVVLYGFGRIGRLLARLLIertgrSNKlRLRAIVLRGgKkGDLEKRASLLRRDSV--------HGPFNGSVEVDeeNNA 198 Shewanella onei...
WP_007819802 129 RDVVLYGFGRIGRLLARLLIekagsGNGlRLRAVVVRKaAgQDLVKRASLLRRDSV--------HGQFQGTIIVDeeNDT 200 Streptomyces sp...
WP_011747389   6 IRLALNGFGRIGRSILRIWAq---gGYE-DLDLVLIND-I-EALENCAYLFEYDSV--------FGPWRGQVGTA--EKA 69  Paracoccus deni...
WP_023923280   2 ARLAINGLGRMGKLLLRRLI-----DLGrGPEIVLLNDaT-GDAETHALLLEFDTV--------HGRWPTPVAAT--ETG 65  Rhodobacter cap...
1GD1_O        64 --LVVNGKEIIVKAERD-PENLAWGEIGVD--IVVESTGRFTKR 102 Geobacillus stearothermophilus
Q7U825        64 --FSVEGSPLTWSSEKD-PTAVPWTARGVE--MVLEASGKIKTP 102 Synechococcus sp. WH 8102
P58559        66 --VLIDGTPLSFSEYGK-PDDVPWEDFGVD--LVLECSGKFRTP 104 Nostoc sp. PCC 7120
Q7V1Y2        64 --IIIDGKKLAYTSFKN-YLDVPWEKSSVD--IILECTGKNKKP 102 Prochlorococcus marinus subsp. pastoris str. CCMP1986
Q6AS43        77 gtMVINGVPVKILRNARnPREIGWQEHGVK--LVVDSTGAFTDP 118 Desulfotalea psychrophila
Q6F9D5       203 --IIANGNFIKVIYASS-PSEVDYTAYGIDnaLLIDNTGKWRDL 243 Acinetobacter sp. ADP1
Q8EEN1       199 --IIANGTYIQVIYANS-PDEVDYTKYGINdaLVVDNTGIWKDE 239 Shewanella oneidensis
WP_007819802 201 --LIANGNTIRFIYSDD-PATVDYTAYGINdaILVDNTGRWRDR 241 Streptomyces sp. Tu6071
WP_011747389  70 --LVVDGRAIPFHSAPD-LRQLDL--SGVD--IVLECTGMTGSR 106 Paracoccus denitrificans
WP_023923280  66 --LQIAGQRIRLTREKT-LDALPLAEIGVD--LVLDCTGQFKTA 104 Rhodobacter capsulatus
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