1C7V,2AMI,1QX2,3U0K


Conserved Protein Domain Family
EF-hand_1

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pfam00036: EF-hand_1 
Click on image for an interactive view with Cn3D
EF hand
The EF-hands can be divided into two classes: signalling proteins and buffering/transport proteins. The first group is the largest and includes the most well-known members of the family such as calmodulin, troponin C and S100B. These proteins typically undergo a calcium-dependent conformational change which opens a target binding site. The latter group is represented by calbindin D9k and do not undergo calcium dependent conformational changes.
Statistics
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PSSM-Id: 333786
View PSSM: pfam00036
Aligned: 572 rows
Threshold Bit Score: 27.3458
Threshold Setting Gi: 115495
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20
                ....*....|....*....|....*..
1C7V_A       10 ILRAFKVFDANGDGVIDFDEFKFIMQK 36
gi 60391914 375 LRNIFIALDVDNSGTLSSQEILDGLKK 401
gi 115854    23 LGRSFKKMDLDKSGSLSVDEFMSLPEL 49
gi 1345659   23 LGKRFRKLDLDNSGALSIDEFMSLPEL 49
gi 115495    26 LRKRFMKLDRDSSGSIDKNEFMSIPGV 52
gi 52001480  26 LRKRFMKLDKDNSGTIEREEFLSLPQI 52
gi 730329   335 LEETFQKADADHSGKLSFEEFQHFVSL 361
gi 730481   531 LVAIFNIIDADNSGEITLDEFETAIDL 557
gi 12643541 571 LEIIFNAIDTDHSGLISVEEFRAMWKL 597
gi 417490   274 LLEFFQLADINHNGLLNYFEFEKFIKI 300
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