1C7V,2AMI,1QX2,3U0K


Conserved Protein Domain Family
EF-hand_1

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pfam00036: EF-hand_1 
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EF hand
The EF-hands can be divided into two classes: signalling proteins and buffering/transport proteins. The first group is the largest and includes the most well-known members of the family such as calmodulin, troponin C and S100B. These proteins typically undergo a calcium-dependent conformational change which opens a target binding site. The latter group is represented by calbindin D9k and do not undergo calcium dependent conformational changes.
Statistics
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PSSM-Id: 333786
View PSSM: pfam00036
Aligned: 572 rows
Threshold Bit Score: 27.3458
Threshold Setting Gi: 115495
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1C7V_A  10 ILRAFKVFDANGDGVIDFDEFKFIMQK 36  amphioxus
Q8ICR0 375 LRNIFIALDVDNSGTLSSQEILDGLKK 401 Plasmodium falciparum 3D7
P28470  23 LGRSFKKMDLDKSGSLSVDEFMSLPEL 49  Norway rat
P48451  23 LGKRFRKLDLDNSGALSIDEFMSLPEL 49  fruit fly
P25296  26 LRKRFMKLDRDSSGSIDKNEFMSIPGV 52  Saccharomyces cerevisiae S288c
P87072  26 LRKRFMKLDKDNSGTIEREEFLSLPQI 52  Neurospora crassa OR74A
P40977 335 LEETFQKADADHSGKLSFEEFQHFVSL 361 Schizosaccharomyces pombe 972h-
P40421 531 LVAIFNIIDADNSGEITLDEFETAIDL 557 fruit fly
O14829 571 LEIIFNAIDTDHSGLISVEEFRAMWKL 597 human
P32383 274 LLEFFQLADINHNGLLNYFEFEKFIKI 300 Saccharomyces cerevisiae S288c
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