1TFG,2QCW,4MID,2BHK,1ZKZ,2QCQ,1NYS,3HH2,2ASK,3FUB


Conserved Protein Domain Family
TGF_beta

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pfam00019: TGF_beta 
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Transforming growth factor beta like domain
Statistics
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PSSM-Id: 333771
View PSSM: pfam00019
Aligned: 332 rows
Threshold Bit Score: 48.0651
Threshold Setting Gi: 637329122
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1TFG_A        13 DNCCLRPLYIDFkRDLGW--KWIHEPKGYNANFCAGACpy-----lWSSD-------TQHS---RVLSL---YNTIN--- 69
gi 620969769 169 GSCRRVNMVVDF-NQLPWg-KWVLAPKSFDAYQCQGTCst-----pPQHSn------VNYA---VIMGL---LHHLQ--- 226
gi 752881735 272 KDCCREDLYINF-RDIGWg-DWILHPSGYHAYFCRGSC---------STAtsltnigSSYN---NVIMKlltKDGs---- 333
gi 830260027 256 NECCREPLYISF-KDLGWd-YWIIRPAGYHAYFCKGSC---------APIsavttskSYHH---DIIRKyfyTVS----- 316
gi 321476996 245 tQCCRESLFVSF-KDVGWd-DWIVAPSGFHAFYCRGSC---------RTMtapassaNTHA---SLLQKlvaRERV---- 306
gi 189233535 459 TDCCRQIFRVHF-LDLGW--DWVISPRGFDANYCRGSCsnfn------------spsLTHT---SIMHTareKNPNFn-- 518
gi 260809353 300 RSCCRRSLVVSF-KDIGWd-GWVMEPAEFDAHYCLGQCasy-------------nlpSPHA---AIMDQvvsPVYEM--- 358
gi 444725097  91 RLCRLQERKVNL-HRAAWg-ECIVAPKTFSFPSCQGTClalnselpQSNFecykreaPTCS---WLFQV----------- 154
gi 193788677 289 HRCCRRRKYVDF-RDLSWtsRWIIEPAGFEAFDCYGPChn---------------lrSRHIrd------------iFrlp 340
gi 992219158 252 NACRLSVHHVDV-HKSDLa-QWILQPAWFNISFCRGMCik----ekSELSvdelkqyERHWeniTIQSL----------- 314
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
1TFG_A        70 -------P-E-ASA-SPCCVSQ--DLEPLTILY-Yi----gKTPKIEQLSNMIVKSCKC 111
gi 620969769 227 -------P-TyAVS-TPSCVPI--RMSPQNLIV-Tde---dQSMAIHYLEDMVVEECGC 270
gi 752881735 334 ---------QqRSKiVPCCSPT--QLAPLQLLY-Idt---nNTITQKTLPNMSVEACGC 377
gi 830260027 317 ---------ErVAEfKPCCAPT--TFSSLQLLY-Ids---tNTVTQKTLPNMVVESCGC 360
gi 321476996 307 -------PiEaRPHlAPCCAPT--RLSPLVIFY-Sde---nNVIKQRTLPNMIVESCGC 352
gi 189233535 519 ------iPr-------PCCTPR--STGTLSMIY-Ine---dGQFYTVDMPEMRILSCGC 558
gi 260809353 359 -------K--------PCCVPVpgQMRDLLIRYsFdg---gKTISTQHIPNIIVNTCGC 399
gi 444725097 155 ------------------CGPT--RAKLFSLMV-Qdd---eYKMSVHYMNTSLTEACGC 189
gi 193788677 341 fyggspsGlPsRSGgHRTCGVS--RSSALPMMYlSatesgaVELKVEEIPNMIVEDCSC 397
gi 992219158 315 -----------------HCIPQ--ELSPLRVMY-Rsp---tSDIMIKEIKDIRAERCVC 350
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