1AWW,1OOT


Conserved Protein Domain Family
SH3_1

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pfam00018: SH3_1 
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SH3 domain
SH3 (Src homology 3) domains are often indicative of a protein involved in signal transduction related to cytoskeletal organisation. First described in the Src cytoplasmic tyrosine kinase. The structure is a partly opened beta barrel.
Statistics
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PSSM-Id: 333770
View PSSM: pfam00018
Aligned: 58 rows
Threshold Bit Score: 36.7809
Threshold Setting Gi: 418349
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
1AWW_A         12 VALYDYMPMN-ANDLQLRKGDEYFILEESNL--PWWRARDKNg-QEGYIPS 58
gi 341940635  265 YALYAFNGHD-SSHCQLGQDEPCILLNDQDA--YWWLVKRITdgKIGFAPA 312
gi 347595818 1126 EAAYDFPGSGsSSELPLKKGDIVFISRDEPS--GWSLAKLLDgsKEGWVPT 1174
gi 325511390  162 RAIANYEKTS-GSEMALSTGDVVEVVEKSES--GWWFCQMKA--KRGWIPA 207
gi 134966       6 TAISDYENSSnPSFLKFSAGDTIIVIEVLED--GWCDGICSE--KRGWFPT 52
gi 325511390  232 VAIKAYTAVE-GDEVSLLEGEAVEVIHKLLD--GWWVIRKDD--VTGYFPS 277
gi 121742     282 RAILPYTKVPdTDEISFLKGDMFIVHNELEDgwMWVTNLRTD--EQGLIVE 330
gi 114914      78 KAKYSYQAQT-SKELSFMEGEFFYVSGDEKD---WYKASNPStgKEGVVPK 124
gi 730721      30 RALYDYTARK-ATEVSFAKGDFFHVIGRENDk-AWYEVCNPAagTRGFVPV 78
gi 1346669    246 RVLFGFVPET-KEELQVMPGNIVFVLKKGND--NWATVMFNG--QKGLVPC 291
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