1WE8,1VIG,1J5K,1X4N,1WVN,2HH2,2ANN,2ANN,1DTJ,2CTE,2CTL,3VKE,2CTM,2JZX,2CTJ,2N8L,2DGR,2CTK,3CDI,4AM3,4NBQ


Conserved Protein Domain Family
KH_1

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pfam00013: KH_1 
Click on image for an interactive view with Cn3D
KH domain
KH motifs bind RNA in vitro. Autoantibodies to Nova, a KH domain protein, cause paraneoplastic opsoclonus ataxia.
Statistics
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PSSM-Id: 333765
View PSSM: pfam00013
Aligned: 891 rows
Threshold Bit Score: 29.5431
Threshold Setting Gi: 13432006
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1WE8_A          17 EQLSVPQRsVGRIIGRGGETIRSICKAS-GAK-IT-C----DkesegtlllsrLIKI--SG-TQKeVAAAKHLILE 82
gi 74956042     83 YKFEMPSKdIGFLIGKNGAKINEIKL-SsNVD-VHfErnneNrdng---etdgRVVVsvTGnYQQ-ILIGLRLIYD 152
gi 74630245    327 AEMDIEAEtVEFLCGKKNGKITRIMRDV-CCG-IVi-----Hkkqg---spriHMVI--NG-CSGaFQKAMQMIED 389
gi 167525619   272 LQFSIPEAiVGRIIGKSGRTIRHIQDVS-GAF-ARvVn--qAypale--paqrILQL--SGtNSQ-LKRALQMCVR 338
gi 1023181434  532 FQIELANEhREFISGKKNGKVNKVMKQC-GVR-IKfEt---Fndy------nfLIDV--SGnDRNgVLQGLGLLQE 594
gi 164656178   598 FQLELATDhREFISGKKNGKINKIMEGC-GVR-IRfEp---Fndy------nfLIEV--LGrEPDaALQGLSQLQE 660
gi 1018896615  874 FQIELANEhREFISGKKNGKINKIMQTT-NVK-IKfEt---Fndh------nfLIDI--AGpD-GsVLQGLSLLQE 935
gi 156368294   182 WEIEFPQIlCGRLIGRKGKNVKAISDQS-GAK-IRlI----Pqspge-vsthrIISL--SG-DSSqIKSALDSIHD 247
gi 308498822   181 YEFEIPNSlVGLIIGVKGKTIKELSQRT-NVR-MLiRq---Hhapdk-skshqICQV--RG-KRDeINHCLQMLRR 247
gi 294948288   757 IEFTIPEDtVRLVIGAKGRTIQRIKAVS-GVSsIDfEh---Aeeg------vsKCRI--SG-QLEsISRAEEMVKA 819
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