3P27,4ZKD,3J5Y,1R5B,4CRN,1HA3,1G7S,3WBJ,5A9W,3CB4,2YWE,3JB9,5YLZ,1ZM3,6NOT,5VH6,2EFG


Conserved Protein Domain Family
GTP_EFTU

?
pfam00009: GTP_EFTU 
Click on image for an interactive view with Cn3D
Elongation factor Tu GTP binding domain
This domain contains a P-loop motif, also found in several other families such as pfam00071, pfam00025 and pfam00063. Elongation factor Tu consists of three structural domains, this plus two C-terminal beta barrel domains.
Statistics
?
PSSM-Id: 394968
View PSSM: pfam00009
Aligned: 144 rows
Threshold Bit Score: 107.223
Threshold Setting Gi: 835020484
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3P27_A   31 LPHLSFVVLGHVDAGKSTLXGRLLYDLNIVNQsqLRKlqrESeTXGkssfk--fawiXDQTNEERERGVTVSICTSHFS- 107  baker's yeast
Q22174  169 VR---LAVVGGCDVGKSTLCGVLTQGCLDDGNgkARIg-------------------IFRFPHEVRTGKTSSVCNDVIGf 226  Caenorhabditis elegans
O27253  116 REHLLVGVAGHVDHGKSTLLGTLTTGTPDDGSgkTRIf-------------------LDVQKHEIERGLSADLSFAIYGf 176  Methanothermobacter...
O29514  156 KEHILVGTAGHVDHGKSTLVGCLITGKPDDGDgaTRVy-------------------LDVLKHEIERGLSAEISFAVFGy 216  Archaeoglobus fulgidus
4ZKD_A   17 PLNLTCLFLGDTNAGKSTLLGHLLYDLNEISMssMRElqkKS-SNLdpsssnsfkviLDNTKTERENGFSMFKKVIQVEn 95   baker's yeast
1G7S_A    3 IRSPIVSVLGHVDHGKTTLLDHIR---------------------------------GSAVASREAGGITQHIGATEIPm 49   Methanothermobacter...
O29490   11 LRTPIVAVLGHVDHGKTTLLDRIR---------------------------------KSKVVAKEAGGITQHIGATEVPl 57   Archaeoglobus fulgi...
O60841  629 LRAPIICVLGHVDTGKTKILDKLRHTHVQDGEagGIT---Q--QIG-----------ATNVPLEAINEQTKMIKNFDREn 692  human
3WBJ_A    7 LRSPICCILGHVDTGKTKLLDKIR---------------------------------QTNVQGGEAGGITQQIGATYFPi 53   Saccharomyces cerev...
P34617   40 DKIRNFGIVAHVDHGKSTLADRLLEMCGAVPPgqKQM--------------------LDKLQVERERGITVKAQTAALR- 98   Caenorhabditis elegans
3P27_A  108 ----------------------THRANFTIVDAPGHRD-FVPNAIXG--ISQADXAILCVDCS--------TNafesgfd 154  baker's yeast
Q22174  227 dnrgklvny---aqnsleemveKSSKLVTLIDLAGDAK-YQKTTIHGltGYTPHFACLVVAAD--------RG------- 287  Caenorhabditis elegans
O27253  177 rdgrpmrlknpldrkeksrlmdEADRVISFVDTVGHEP-WLRTTIRGivGQKLDYGLLTVAAD--------EG------- 240  Methanothermobacter...
O29514  217 kdgkvlrmknplskaekamvveTADKLVSFVDTVGHEP-WLRTTIRGllGQKVDYGLLVVAAN--------DG------- 280  Archaeoglobus fulgidus
4ZKD_A   96 d-------------------llPPSSTLTLIDTPGSIKyFNKETLNSilTFDPEVYVLVIDCNydswekslDG------- 149  baker's yeast
1G7S_A   50 dviegicg-----dflkkfsirETLPGLFFIDTPGHEA-FTTLRKRG--GALADLAILIVDIN--------EG------- 106  Methanothermobacter...
O29490   58 dvikqic--------kdiwkveVKIPGLLFIDTPGHKA-FTNLRRRG--GALADLAILIVDIN--------EG------- 111  Archaeoglobus fulgi...
O60841  693 ----------------------VRIPGMLIIDTPGHES-FSNLRNRG--SSLCDIAILVVDIM--------HG------- 732  human
3WBJ_A   54 daikaktk-----vmaeyekqtFDVPGLLVIDTPGHES-FSNLRSRG--SSLCNIAILVIDIM--------HG------- 110  Saccharomyces cerev...
P34617   99 ----------------------HRGYLLNLIDTPGHVD-FSAEVSRS--LAVCDGILLLVAAN--------QG------- 138  Caenorhabditis elegans
3P27_A  155 LDGQTKEHXLLASSLGIHn-----LIIAXNKXDNVdw--------sQQRFEEIKSKLL-PY-------LVDIgFFEdn-- 211  baker's yeast
Q22174  288 ITWATREHLGLIAALNIP------MFVLITKMDLVd----------RQGLKKIIKDVSnLV--------------Akagm 337  Caenorhabditis elegans
O27253  241 PTHITREHLGIMIAMELP------VIVVLTKCDMAa----------DENRRGVREKISeLLklvgripfhvkslda---- 300  Methanothermobacter...
O29514  281 VMRTTKEHLGIMLAMDLP------VIVAVTKADMVd----------DARLSEVLQEISaTLrrvgrvptvlksrhda--- 341  Archaeoglobus fulgidus
4ZKD_A  150 PNNQIYEILKVISYLNKNsackkhLIILLNKADLIsw--------dKHRLEMIQSELNyVL-------KENFqWTDae-- 212  baker's yeast
1G7S_A  107 FKPQTQEALNILRMYRTP------FVVAANKIDRIhgwrvhegrpfMETFSKQDIQVQqKLdtk-vyeLVGKlHEEgfes 179  Methanothermobacter...
O29490  112 FKPQTEEALSILRTFKTP------FVVAANKIDRIpgwqshedtpfMKSYAMQEDFAKqNLenr-lynLIAElYQRgfsa 184  Archaeoglobus fulgi...
O60841  733 LEPQTIESINLLKSKKCP------FIVALNKIDRLydwkkspdsdvAATLKKQKKNTKdEFeerakaiIVEF-AQQglna 805  human
3WBJ_A  111 LEQQTIESIKLLRDRKAP------FVVALNKIDRLydwkaipnnsfRDSFAKQSRAVQeEFqsr-yskIQLElAEQglns 183  Saccharomyces cerev...
P34617  139 VQAQTIANFWLAFEKNIQ------IIPVINKIDLP-----------GADIKSVETQLKnLFefn---------------- 185  Caenorhabditis elegans
3P27_A  212 -------------------------inWVPISGFSGEGVYkieytdev------------rqwyngpNLXSTLENAAFK 253  baker's yeast
Q22174  338 tarekrvktkrdavkaaqelcvgsivpVLAVSSVSGEGFR----------------------------CLRTLLNCLST 388  Caenorhabditis elegans
O27253  301 -------------aagiagkmnqhivpIIETSSVTGEGLE----------------------------ILDELFLNLRV 338  Methanothermobacter ...
O29514  342 ------------rkaaemvksnkllvpVVITSAVTLEGYD----------------------------ILEEIFLHLPK 380  Archaeoglobus fulgidus
4ZKD_A  213 -------------------------fqFIPCSGLLGSNLNktenitkskyksefdsinyvpewyegpTFFSQLYLLVEH 266  baker's yeast
1G7S_A  180 erfdr-------------vtdfasqvsIIPISAITGEGIP---------------------------ELLTMLMGLAQQ 218  Methanothermobacter ...
O29490  185 erfdr-------------isdftrtvaVVPISALKGEGIP---------------------------ELLLILVGLAQR 223  Archaeoglobus fulgid...
O60841  806 alfye-------------nkdprtfvsLVPTSAHTGDGMG---------------------------SLIYLLVELTQT 844  human
3WBJ_A  184 elyfq-------------nknmskyvsIVPTSAVTGEGVP---------------------------DLLWLLLELTQK 222  Saccharomyces cerevi...
P34617  186 ------------------------peeCLHISAKSGLNVD---------------------------KVLEAIIDRVPA 213  Caenorhabditis elegans
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap