4MYC,3GD7,3J5S,3J5S


Conserved Protein Domain Family
ABC_tran

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pfam00005: ABC_tran 
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ABC transporter
ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide as in CFTR, or belong in different polypeptide chains.
Statistics
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PSSM-Id: 333758
View PSSM: pfam00005
Aligned: 59 rows
Threshold Bit Score: 93.0917
Threshold Setting Gi: 127359
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4MYC_A        355 LKNASFTIPAGWKTAIVGSSGSGKSTILKLVFRFYDP--ESGRILIN-GRDIKE--------YDIDALRKVIGVVPQD-- 421
gi 728775      41 LRDIELTVYRGETIGIVGHNGAGKSTLLQLITGVMQP--DCGQI---------------------TRTGRVVGLLELG-- 95
gi 585570      30 LRGLDMYVRRGERYGIMGTNGAGKSSLINIILGLTPP--DRGTVTVF-GKDMRR---------QGHLARARIGVVPQD-- 95
gi 341940621  916 VDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPP--TSGTAYIL-GKDIRS---------EMSSIRQNLGVCPQH-- 981
gi 45644964   406 LNEISGIVKPGQILAIMGGSGAGKTTLLDILAMKRKTghVSGSIKVN-GISMDR-----------KSFSKIIGFVDQD-- 471
gi 464819     176 LKPMDGCLNPGELLVVLGRPGSGCTTLLKSISSNTHG--------FDlGADTKIsysgysgdDIKKHFRGEVVYNAEA-- 245
gi 398987      22 LNSLNLSIKPGEIHAIMGKNGSGKSTLAKVIAGHPSYkiTNGQILFE-NQDVTE---------IEPEDRSHLGIFLAFqy 91
gi 1709072    276 LNNLSWQVNPGEHWQIVGPNGAGKSTLLSLVTGDH----PQGY-----SNDLTLfgrrrgsgETIWDIKKHIGYVSSS-- 344
gi 13878959    19 LKDITWKVNPGENWVILGLNGSGKSSLLKLILAEEWK--TSGEITVL-NTQFGN--------GEIPKLRKRISVVGSFia 87
gi 126811      23 FNNLSLKIEQGELIGLLGENPAGKTTLFNLIRGGVSN--YEGTLKRN-------------------FSGGELVSLPQV-- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4MYC_A        422 TPLFND-T-IWENVKFGridAT---DEEVITVVEKAQ--------LAPLIKKLPQGF---DTIVge-rgLMISGGEKQ-- 482
gi 728775      96 SGFNPEfT-GRENIFFN---GA---ILGMSQREMDDR--------LERILSFAAIGDf-iDQPV-----KNYSSGMMV-- 152
gi 585570      96 DCLEQNmT-PYENVMLY---GR---LCRMTASEARKR--------ADQIFEKFSMMDc-aNRPV-----RLLSGGMRR-- 152
gi 341940621  982 NVLFDMlT-VEEHIWFY---AR---LKGLSEKHVKAE--------MEQMALDVGLPPsklKSKT-----SQLSGGMQR-- 1039
gi 45644964   472 DFLLPTlT-VFETVLNS---ALlrlPKALSFEAKKAR--------VYKVLEELRIIDi-kDRIIgnefdRGISGGEKR-- 536
gi 464819     246 DVHLPHlT-VFETLVTV---AR---LKTPQNRIKGVDresyanhlAEVAMATYGLSHt-rNTKVgndivRGVSGGERK-- 315
gi 398987      92 PVEIPGvT-NADFLR----------IAYNAKRAFDNKeeldplsfFSFIENKISNIDl-nSTFLsrnvnEGFSGGEKK-- 157
gi 1709072    345 LHLDYRvStTVRNVILS---GYf-dSIGIYQAVSDRQ--------QKLVQQWLDILGi-dKRTAda-pfHSLSWGQQR-- 408
gi 13878959    88 ERFQPNi--KAENLVYT---GKf-nSSMLYKPYTDQE--------LDEARQLLRQMGa--KSLIgr-nyASLSQGEKQ-- 148
gi 126811      80 INLSGTlR-NEEVLDLI--------CCFNKLTKKQAW--------TDVNHKWNDNFFi-rYDKIrrkrtYTVSYGEKRwl 141
                         170       180
                  ....*....|....*....|..
4MYC_A        483 RLAIARVLLKNARIMFFDEATS 504
gi 728775     153 RLAFSVIINTDPDVLIIDEALA 174
gi 585570     153 LTMVARALVNDPYVIILDEATV 174
gi 341940621 1040 KLSVALAFVGGSKVVILDEPTA 1061
gi 45644964   537 RVSIACELVTSPLVLFLDEPTS 558
gi 464819     316 RVSIAEVSICGSKFQCWDNATR 337
gi 398987     158 KNEILQMSLLNSKLAILDETDS 179
gi 1709072    409 LALIVRALVKHPTLLILDEPLQ 430
gi 13878959   149 VLLIARSLILKPELLILDEATN 170
gi 126811     142 IISLMVTLCKNARLFLLDEPTV 163
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