4QF3


Conserved Protein Domain Family
PHD_BAZ2B

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cd15630: PHD_BAZ2B 
Click on image for an interactive view with Cn3D
PHD finger found in bromodomain adjacent to zinc finger domain protein 2B (BAZ2B)
BAZ2B, also termed WALp4, is a bromodomain-containing protein whose biological role is still elusive. It shows high sequence similarly with BAZ2A, which is the large subunit of the SNF2h-containing chromatin-remodeling complex NoRC that induces nucleosome sliding in an ATP-and histone H4 tail-dependent fashion. BAZ2B contains a TAM (TIP5/ARBP/MBD) domain, an Apolipophorin-III like domain, a DDT domain, four AT-hooks, BAZ 1 and BAZ 2 motifs, a WAKZ (WSTF/Acf1/KIAA0314/ZK783.4) motif, a plant homeodomain (PHD) finger, and a bromodomain.
Statistics
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PSSM-Id: 277100
Aligned: 4 rows
Threshold Bit Score: 80.4025
Created: 21-Mar-2014
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Zn binding siteH3 histone
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C C H C C CClick to see conserved feature residue pattern help
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           #  #           #  #    #  #              #  #  
4QF3_A          7 VYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIA 55   human
AAI42905      197 VYCQICRKGDNEDLLLLCDGCDKGCHTYCHKPKITTIPEGDWYCPDCIS 245  zebrafish
Q9DE13       1896 VYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIA 1944 chicken
XP_004917752 1905 VYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPEGDWFCPACIA 1953 western clawed frog

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