Conserved Protein Domain Family
RabL3

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cd04102: RabL3 
Rab GTPase-like family 3 (Rab-like3)
RabL3 (Rab-like3) subfamily. RabL3s are novel proteins that have high sequence similarity with Rab family members, but display features that are distinct from Rabs, and have been termed Rab-like. As in other Rab-like proteins, RabL3 lacks a prenylation site at the C-terminus. The specific function of RabL3 remains unknown.
Statistics
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PSSM-Id: 206689
View PSSM: cd04102
Aligned: 6 rows
Threshold Bit Score: 277.551
Threshold Setting Gi: 78707722
Created: 14-Feb-2006
Updated: 17-Jan-2013
Structure
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Aligned Rows:
  next features
Feature 1:GTP/Mg2+ binding site [chemical binding site]
Evidence:
  • Comment:Based on sequence similarity to Rab family proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                #######               ##                                         #      
NP_001025951   7 VKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDVRIHDYKEGt-----------pEEKTYYIELWDVGGsvgsaT 75  chicken
AAH73035       7 VKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRLHEYREGt-----------pEEKTYYTELWDVGGsvgsaS 75  African clawed ...
AAQ91252       7 VKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYREGt-----------pEEKAFYIELWDVGGsvgsaS 75  zebrafish
CAI46059       7 VKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYKEGt-----------pEEKTYYIELWDVGGsvgsaS 75  human
ABB46697      28 VRVLVVGDSGVGKSSLVHLILKGSAIARPPQTIGCAVDVKHITYGSPgsssnsinsikgdAERNFFVELWDVSGh----E 103 Japanese rice
AAK64108      23 VRVLVVGDSGVGKTSLVHLINKGSSIVRPPQTIGCTVGVKHITYGSPassss---siqgdSERDFFVELWDVSGh----E 95  thale cress
Feature 1                                                                               ## #     
NP_001025951  76 SVKSTRAVFYNSLNGIILVHDLTNKKSSQNLYRWSLEALNrdvaptgvlvtngdydreqfadnqIPLLVIGTKLDqip-- 153 chicken
AAH73035      76 SVKSTRAVFYNAVNGIILVHDLTNKKSSQNLYRWSLEALNrdlqpmgvlvtngdydreqfadnqIPLLVIGTKLDqip-- 153 African clawed ...
AAQ91252      76 SVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEALSkdssptgiivsngdydreqfaenaVPLLLIGTKFDqip-- 153 zebrafish
CAI46059      76 SVKSTRAVFYNSVNGIIFVHDLTNKKSSQNLRRWSLEALNrdlvptgvlvtngdydqeqfadnqIPLLVIGTKLDqih-- 153 human
ABB46697     104 RYKECRSLFYSQINGVIFVYDLSQRKTKTNLNKWAVEVAEsgtfsaplg-------sggpgglpVPYLVIANKVDiaprd 176 Japanese rice
AAK64108      96 RYKDCRSLFYSQINGVIFVHDLSQRRTKTSLQKWASEVAAtgtfsaplp-------sggpgglpVPYIVVGNKADiaake 168 thale cress
Feature 1                                              #                               
NP_001025951 154 ----------etkRNEVLTRTAFLAEDFNAEeinldctNPRYLAAGSSN---AVKLSRFFDKVIEKRYFF 210 chicken
AAH73035     154 ----------eakRNEVLTRTAFLAEDFNAEeinldctNTRCLAAGSSN---AVKLSRFFDKVIEKRYPR 210 African clawed frog
AAQ91252     154 ----------enkRNDVLTRTAFLSEDFNAEeinldctNPRYLAAGSSN---AVKLSRFFDKVIEKRYFT 210 zebrafish
CAI46059     154 ----------etkRHEVLTRTAFLAEDFNPEeinldctNPRYLAAGSSN---AVKLSRFFDKVIEKRYFL 210 human
ABB46697     177 gkrvssgnlvdvaRQWVEKQGLLPSSEELPLaesfpgnSGLLTAAKVARy-dKEALVKFFRMLIRRRYFS 245 Japanese rice
AAK64108     169 gtkgssgnlvdaaRHWVEKQGLLPSSSEDLPlfesfpgNGGLIAAAKETrydKEALNKFFRMLIRRRYFS 238 thale cress

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