Conserved Protein Domain Family
GT4_WcaC-like

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cd03825: GT4_WcaC-like 
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins
This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
Statistics
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PSSM-Id: 340851
Aligned: 16 rows
Threshold Bit Score: 353.56
Created: 12-Jan-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAD40721    2 KTLFQINVVAnsGSTGHIAEELGRLVIASGWKSYIAYGRWAcptqsmlirvgtrfdlfvh-------------glksmff 68  Bacteroides fragilis
AAM22589    3 MKVTHVNSGDl-IGRRFNGYDLKPYLSDLGVETSQLVYWNKqsnadfvhqafdypgsryitr----------avnlveqr 71  Vibrio cholerae O37
NP_220719   1 MKILQINGYEs-PGRRFHGLSITQILKKYGIESKHLVWAKDtqdpevltfegiiprkinqi------------lqlienq 67  Rickettsia prowaze...
YP_009112   1 MNILTITALPa-GGATYAAQRLHSALVEYGHACTLACCDPVqpghvalnyqrpdatpfmsplfrywstlstpetreqgac 79  Desulfovibrio vulg...
AAS83057   22 MRVLTVSLADqeGGAERIAFRLTAGYRFAGHEATLAVGFKRldhdwvrplsrdrnrpsrnpaapp----pagpddrkwal 97  Azospirillum brasi...
EDQ01568    1 MKVLHIIAGDlsGGAAKGAYNLHKALITSGESSHIFNNTLSkndpsvsvsinsdkkkvlevlkrk---iealvlkfypkr 77  Shewanella benthic...
AAO78052    1 MRVLIINTSEriGGAAVAAGRLMESLKNNGIKAKMLVRDKQtdqisvvglkgswlhvwkfmweri----viwkanrfkkn 76  Bacteroides thetai...
EDN36538    1 MKILIVNTSDiqGGAARAAYRLHKSLLEANIDSQMLVQSKAsddctvitedsrlrrylnklrpii---dglpvrkykhri 77  Francisella tulare...
NP_683179   1 MKVYHLNHFDiiGGAARAAYRIHHALREVGVDSTLLVDVGMsgdwtvqgpttkfgkalarlrpam---vqlllksvfktg 77  Thermosynechococcu...
YP_011021   3 LAVVHHTFFAhrGGAARVANLLHQRLGAEGVDSRRTAEVADaat------------------------------------ 46  Desulfovibrio vulg...
AAD40721   69 drhgfgsrratlHLISKIEKIKp---DIIHLHnlhGYYLNCEVLFdylstakiPVVWTLHDCWSFTGHCVHFQNIGCekw 145 Bacteroides fragilis
AAM22589   72 lslhaklhphswALPYHAEIKNa---DLVHMHiihDGFFSMDAIPfls--rrkPIVWTWHDPWPMTGHCIYPMECDKwk- 145 Vibrio cholerae O37
NP_220719  68 tslqsilyrnvsKIIKMPAFQEa---DLIHLHiihSGYFSISDLSmit--dlkPTIWTLHDPWAMTGRCIYPMGCLGwr- 141 Rickettsia prowaze...
YP_009112  80 elfsdtstllasPALPDHIVEAa---DVVHLHw-aSGILYSPALFrll--rnkKLVWTLHDMNPFTGGCHYHVSCERye- 152 Desulfovibrio vulg...
AAS83057   98 ragmedffypgsWDLLDLADDPp---DLVHLHnlhNAYFDLRVLPwls--trvPVVMTLHDCWLLTGHCAHPMECERwr- 171 Azospirillum brasi...
EDQ01568   78 idrifsmgfvgfNFIKTNEYKEa---DIIHLHwinSSFVNMKILAni----dkPIIWTVRDMWPLTGGCHYSLDCTRyt- 149 Shewanella benthic...
AAO78052   77 dlfavdiantgtDITSLPEFQQa---DVIHLHwinQGMLSLNTIRkilt-sgkPVVWTMHDMWPCTGICHYARECKNye- 151 Bacteroides thetai...
EDN36538   78 ktlfspswfgfnNIVTKINKINp---DIVHLHwinGGMLKIEDIAki----kaPIIWSLHDNWAFTGGCHIKWDCVKyk- 149 Francisella tulare...
NP_683179  78 npsphspallpsGRVAALNQSDv---DIVHLHwvqGEMLSIADIGrl----rkPVVWTLHDMWAFCGAEHYAEDCRW--- 147 Thermosynechococcu...
YP_011021  47 ----------gcTLVSPDAVAAvargALIHLHataDWLLALSALRgh-----pRVVITLHDAALLTGGCIQPFDCPGwh- 110 Desulfovibrio vulg...
AAD40721  146 ktGCFACPNIRDYPkalgcdnSRMNFIEKKRlftsverMMIVPVCNWLSDMlsksy---lsqiKRQTIVNGIDLEMftPK 222 Bacteroides fragilis
AAM22589  146 -tGCGNCPNLEAPFrmr--kdRTKQQFSWKNniykktkAEVVLASKWMLDMa----------qNSPFSEYFNFTQIpfGL 212 Vibrio cholerae O37
NP_220719 142 -kDCGVCPDLNTPFamk--kdNSRFLFNYKRmayekanFDIIIASKWMKDMvysspmfndkeiKIHHLPFGIDLEFfsSD 218 Rickettsia prowaze...
YP_009112 153 -hECGNCPLLAHPApnd--vsLQAHRFKRLLyre--ldITMVSPSAWLADKarrsp--lftgkKVAVIPNTHDTTLfaPR 225 Desulfovibrio vulg...
AAS83057  172 -tGCGMCPDLSIYPplp--rdNTANNWDRKRdllgasrFFLAAPCDWLRERalgslp-pssvrAAVTLPNGVDIEAfqPG 247 Azospirillum brasi...
EDQ01568  150 -aNCGKCPQLGSNNef----dLSRIILNRKIkyl-prnLTAVGISPWVSEIlnrst--lfkdkRVVQINNCIDTTEffPI 221 Shewanella benthic...
AAO78052  152 -qECHHCPYIYGGGgk---kdLSTRIFRKKKeiysqasITFVGCSRWLAEKakvsg--lltgqTVISIPNAINTNLfkPH 225 Bacteroides thetai...
EDN36538  150 -qHCQSCPNLASKKdk----dLSFKVFRRKKkvfakkdFIIVGLSSWLNNLskqsf--llknnKHINLPNPINTDIfkPF 222 Francisella tulare...
NP_683179 148 --RQGYCRDNQRSDesg--fdLNRWTWLCKCkhw-kkpMQIVTPSRWLAQCvresa--lmrdwPVSVIPNPINTERwqPV 220 Thermosynechococcu...
YP_011021 111 qgCLSPCPRGYANAe-----eRQRHLRELLYel----aPYLVSPSGWLARMvrqa----lpglSCAVVPNGVSIPE--TI 175 Desulfovibrio vulg...
AAD40721  223 GNRDVIKSNLGVGTRYMILAVATVWGi-------TKGFDDLIYLNSLLp-------dKSVIVVVGVTTKQIkk-lPGNMI 287 Bacteroides fragilis
AAM22589  213 DLEKYRPRDKKVARERLGIFPDRAVEfirasstpFKGLREFVEALALInpel--klcIIALQEVGHFDQFIg---KHQII 287 Vibrio cholerae O37
NP_220719 219 FTVSARKRFNISEDKIVISFRSEDTH--------FKGYQYIMAALEKLett----ksICLLTVGRHNTLERfr-gKFDII 285 Rickettsia prowaze...
YP_009112 226 DRASLRSQYGVEKDTFIVLTGVESLDn------pRKNIGCMVEAMEQFaqrr--phiSFELVLFGAGGANLl--aSFPTR 295 Desulfovibrio vulg...
AAS83057  248 DRRAARDRFGVPQDAVVALLVSNGGLan-----lWRDVRTLEEAVRAAaarl--aprRILLLVAGGLEERTrw-gSVEVW 319 Azospirillum brasi...
EDQ01568  222 SKKKAREVLGIKTDKNILLMGANSVTd------fYKGFDKCIESLKKLdt------qRYFLLFFGNLDESSvidlGFEYR 289 Shewanella benthic...
AAO78052  226 NKQEARRKCRLPQEGKLILFGSVKITd------kRKGIDYLIEACKLLaekhpewkeSLGVVVFGNQSQQLqdliPFRVY 299 Bacteroides thetai...
EDN36538  223 DKELSRKLWNLPKDKKLILFGAMDATkd-----iNKGFKELNEALQKIvk-----tdDIELVVFGSSKPTSapdfGFKAN 292 Francisella tulare...
NP_683179 221 EAKLARSLLGFPQDVPLVLFGAIAGGkd-----pRKGFDLLLAALHHLhgq----vaDLQLVVFGEHRPKNppdlGFPIH 291 Thermosynechococcu...
YP_011021 176 DAGAARRALGIGAEAFVVLCLAHGGEtsq--lkgGGLWTTIWDAVKQAv-------pNALGVFVGGDAMRR----DGDLL 242 Desulfovibrio vulg...
AAD40721  288 GIERTEnTSQLVEIYSAADIFINPTYQDTLPTVNIEALACGTPVITYDTGGSADIVDsd--tGMVLKRGdIHTLLEKILE 365 Bacteroides fragilis
AAM22589  288 EFGWSNdEELLLDAYAACDFFAMPSMAEAFGLMAIEAMACGRPVLSFDSTSLEDVSFap-saGISVPRGdTNLLAKAIEE 366 Vibrio cholerae O37
NP_220719 286 ELGWTNdDVLLRDVLSACDIFLMPSVAEAFGVMAIEAMACSKPVIVFDGDNSLPDVTfapdvGIAVPMRdSHALSNAIKH 365 Rickettsia prowaze...
YP_009112 296 HVGSLD-AESLVDWYNMADVFVHPSRLDNLSNTLCEAQCCGTPVISFDAGGSTEAFQdg-etGFISGNQ-PQHLAEALDR 372 Desulfovibrio vulg...
AAS83057  320 SFPFLTdGSGLADIYRAADVFVHFARADTFPTVVLEAMACGLPVVATAVGGIPEQIAdg-etGLLVTPGaVGEAAEALTA 398 Azospirillum brasi...
EDQ01568  290 SMGYITdVISLRLIYSSATIFIAPSIMEAFGKTLIESMACKTPVVCFNATGPKDIVThk-vdGYKAKPFsTTSLANGIEW 368 Shewanella benthic...
AAO78052  300 PLPYIKnEHELVDIYNAVDLFAIPSLEENLPNMVMEAMSCGVPCVGFNTGGIPEMIDhl-hnGYVAQRKsSEDLANGIHW 378 Bacteroides thetai...
EDN36538  293 YLGLLNdDVSLVTLYSAVDVMVVPSLQENLSNTIMESLSCSTPVVAFDIGGNNDMIGhk-knGYLAKPFdSQDLANGIEW 371 Francisella tulare...
NP_683179 292 YTGHLHdDLTLRILYSAADVMVVPSRQEAFGQTASESHACGTPVVAFNTSGLPDIVKhe-etGYLAKPFdPEDLARGIEW 370 Thermosynechococcu...
YP_011021 243 RLPYLD-QAHLHIVRAAADVFIHPSLADNHPLGILEAMAAGLPVCAFDVGGVPEIVRdg-vtGRLVPVGdAATLALVCAE 320 Desulfovibrio vulg...
AAD40721  366 IRErgkesyIIKCRQRALQFfdks--kqlSYYLSLYDQL 402 Bacteroides fragilis
AAM22589  367 LVMdpheceKRGNLSRELAEkhydirmqaQLSFELYDRV 405 Vibrio cholerae O37
NP_220719 366 LIDnpkerlDRGNKSREIAElhysqdlyiKNLVNIYKET 404 Rickettsia prowazekii str. Madrid E
YP_009112 373 LLSsd--meSLRQKARMFAMnrfngkniaQRYTDIYEDD 409 Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
AAS83057  399 LLEdeamrtRLAAAARRRAVahfdervmiERYLAWYAKI 437 Azospirillum brasilense
EDQ01568  369 VVNndn-yeELCEKAREKVVnefdsvvvaKQYISLYKDI 406 Shewanella benthica KT99
AAO78052  379 VLTepeyaeLSAQACRKAIGnyse-siiaKKYTEVYNKI 416 Bacteroides thetaiotaomicron VPI-5482
EDN36538  372 VLAndn-yvSLCENARYKVLrefdskvvaQKYIQLYKET 409 Francisella tularensis subsp. novicida GA99-3549
NP_683179 371 VLSdsvrraQLRKNARARAEqcfasqlvaTQYRQVYESV 409 Thermosynechococcus elongatus BP-1
YP_011021 321 FAAqphvrrGFGKAARDLATrcfderrmaRDYLRVYGTL 359 Desulfovibrio vulgaris
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