Conserved Protein Domain Family
GT4_ExpC-like

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cd03818: GT4_ExpC-like 
Rhizobium meliloti ExpC and similar proteins
This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).
Statistics
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PSSM-Id: 340845
View PSSM: cd03818
Aligned: 10 rows
Threshold Bit Score: 459.136
Threshold Setting Gi: 39982859
Created: 28-Dec-2005
Updated: 9-Jun-2017
Structure
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Aligned Rows:
 
putative
Feature 1:putative ADP-binding pocket [chemical binding site]
Evidence:
  • Comment:Some of the residues involved in ADP binding bind indirectly.
  • Comment:Based on similarity to sequences with known structure

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                   #                                                                    
gi 1890594     4 HVAFVHRRGFGQFAALARHLAEA--GNEVTLVTETVDQRIPs-----VRVVRHRAepgpqpn--phiarhLGVPDHHVRI 74
gi 159178989   2 RILFVHQNMPAQYAHLASHYARDp-KNEVVFLTRRKDLEMPg-----VRKIRYDLsreakt----dghhyVKFLDEHLLY 71
gi 66046317    2 NILIIHQNFPGQFKNLVRDISGRs-TCELTVISRDTTPVYHg-----VRHIRYRPkrsvss----tthnyLRTFEDAVLH 71
gi 161787838   2 RYLFVHQHFPGQYLHLLRHLRQDp-GNEIVFISEPNDNHLPg-----VRRVAYRPprggap----gvhpaARDFDLAMLR 71
gi 66968576    2 NVLFIHQNFPGQFRHIAAHLARQp-GVNVRAIGREHAPGLAg-----IRLYRYRPhrqask----ethpyARTFEEGVLH 71
gi 32456021   39 KLLFVHQNMPGQYRELLDWLAAQg-GHELVFLTQRQNVKIPg-----VQTVVYKPfhqpakd--afglskVWEEAAGAGF 110
gi 33632254    2 RILFVHQNFPGQYVHIVQRLAQQ--GQHQIVALGINALDANrplpeeLQYFRYPLergntkg--ihplvmETETKIIRAE 77
gi 78483937   12 RILFLHLSGPGQFEFLGRWLAGQ--GWDVTFMHGGIDADPA------HDGIRTRRfalrdttiptgdprhILDHAAQNCR 83
gi 33337561    2 NLLFIHGNFPGQFKDIAPALALNtnGKTYFLSLSDNPQNIVlp---rVQFRQFKLhrdvgs----ethayVQSAELAVLK 74
gi 39982859    2 NVVFVHPSYPNQFTGIANALSRKr-GWECAFLVDRAFTGQIrr---dKPPVAYYGygeeasp--lsgtyyTRCIEEGARR 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 1890594    75 GHRVAETFDamg-rlGQSPDIVLGHiGWGSMMFVKDVlPRVPALGYCEFFYRS-EGADVGFAPDDRPDse--------tr 144
gi 159178989  72 GQAVVREAIalk-asGFAPDVICVHsGWGEALFLKDVfPNAPMLVYAEYYYRG-RGSDVGFDMAKEPDfd--------li 141
gi 66046317   72 GQQVLRVLLqle-rtGYRPAVILAHpGWGEALFIKDAfPDTPLINFCEYYYHA-TGADTGFDPEFPASad--------sr 141
gi 161787838  72 AESVARAAAslr-dlGYRPDIVIGHhGWGELLNMGDVfPGVPVLGYFEFFYHA-DALDVGFDPEFPSPrgs------lpv 143
gi 66968576   72 GQQVLRLLLdlk-akGYRPDVIVAHpGWGETLYAKQAfPDCKLIHFCEYYYHN-DGADAGFDPEFPLTlngaasihsrna 149
gi 32456021  111 GAVMALQQFat--ktGFRPDVILGHtGWGELSFLKDLwPDVPIIGYFEYYYNM-EGGMVGFDPERPAGeha------pyf 181
gi 33632254   78 GCARAAEQLka---kGFTPDLICAHpGWGEALFLKAIwPDSPLLCYEEFFYRA-HGFDSNFDPEFDRDwsw------qeq 147
gi 78483937   84 GATELMFRMrh--seGYVPDVVVAHaGWGVGLGVKLVwPDCTYVAYHEWYYTDrNWDKRRAEKPADLAvm--------is 153
gi 33337561   75 GQAVLRALDqlhkqeGFMPDVVICHgGMGFGLFVKSLlPNVRLISYLEWYFTP-SNSQELILNPSINDf----------- 142
gi 39982859   76 GKAIVEALAhi--haSTGIDAVVGHaSFGATLFVREI-LAIPVVSYVELPGYHpAFCRDEFPGRYPQSlm---------d 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 1890594   145 KRLRlrni--aqllSLEAMDGGISPTNWQKSLYPADarqRIAVCHEGVDTRRfRPDPAASLKLPDgrv-----lkaGDPV 217
gi 159178989 142 CRSRarna--hlllSLEAADWSVTPTVWQWQQQPAAyrsRMSVIHDGIRTTVcAPDPTARLPLPNgtv-----lsrDDEV 214
gi 66046317  142 ARLRiins--lhllNLEQCDVGVTPTRWQHSLHPAAyrdKIKVIHEGIDFEGlLGDHRRDLILDDgqi-----vhpGCPI 214
gi 161787838 144 IRARnainlqalagGGDGTVQGQTPTRFQWMTYPAWargGIEILPEGVDLAAcSPDPAAFRRTLRigei---aiapRDRL 220
gi 66968576  150 LHLL----------NLENCDAAITPTRWQHSLHPAAyhdKIKVIHEGIDTANlGPDPDAVLRLPNgqq-----lkaGDPV 214
gi 32456021  182 NRARnvv----pclNRDVVDLGHVPTQWQRDRFPKSfhdSMYVCHDGIRTDKlGPDPKAEIPLGRlaep----lraGDEV 253
gi 33632254  148 ARLNmkna--ylhlTLEQADWHVSPTHFQASSFPEHwqrRISVIHDGVDTRRaAPVANPRPLTLPdgtv----lekGQSI 221
gi 78483937  154 DRMRnlp----itgEFDLADASWCPTLFQASRFPPVlrrQITVMPDGVDCDLhRPDPQARIDFDWlrl------paDRPV 223
gi 33337561  143 CRLEcrni--pilqEAAQADQLVCPTRWQRDQFPAFirdRIQVVFDGVDLDFfSPGPPADPLVLNanresplqftsDQLL 220
gi 39982859  144 VALRsli-----hsSVIHSDLCVVPSAYARDLFPPElrnKVRVRMEGFALPPpAGDREALRRELGit--------gNGPV 210
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1           ###                                                                          
gi 1890594   218 VTFVARDLEPYRGFPQALEAAAKVVRrhPDALFVFVGGDG--VSYGAPPPGGg--sWKDHLLASLdv--pRERLIFPGvV 291
gi 159178989 215 ITYIARNLEPYRGFDRFMRALPALLKrrPNAHVVLVGGDD--ASYGGLPVDAr--sWREKMLAEVrv--dPRRVHFVGrV 288
gi 66046317  215 ITYVARNLEPYRGFHVFMRSLSRILKqhNSVRVVIVGGDG--VSYGSRPRDAa--sWREKMTSDIsv-adLKRIHFLGkV 289
gi 161787838 221 VTYVARDLEPYRGFHVFMRALPRILAarPDVRVVLVGGDG--VSYGARLPAGs---WRARMLAELagridLDRVHFPGkV 295
gi 66968576  215 VTYVARNLEPYRGFHQFMRALPRVLAahPTCQVVVVGGDS--VSYGSKPHDAp--nWRIKLLRENpv--dLSRVHFLGkV 288
gi 32456021  254 VTYIARNMERARGFHVMMRALPEIQAarPNARILMIGGNE--TSYGAESKHPg--gLRGEMEEELgdrvdWNRVHFVGrV 329
gi 33632254  222 ITFVNRSLEPYRGCHTFLRAIPDLQRqsPDARIVIVGETKg-VSYGSPCPDGe---WKDQFLAEIeghydPSGVHFAGtL 297
gi 78483937  224 ITYATRGMEPLRGFPQFLRGVARLQArrDDFDTVILANDS--VSYGRPLARGd--sWWLRMIDQLdl--dHRRIHVNAmR 297
gi 33337561  221 LTYGTRGMEPLRGFPEFMRAAAVAQQtfPQLHVIVFGKDRsaYSYPSPHPSGs---WKQFMLEQLegqldLERLHFTGlL 297
gi 39982859  211 IGFAGRTLEAVRGFDVFVRAVGRIRAvrPDAHFLVVGDET--SIYGNEASYLggasFKQHALRQEgm--eDEEFIFRPfV 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1            #                     #                                                     
gi 1890594   292 PHSVLRQLFQISAAHLYLTYPFVLSWSVLEAMACGALVIGSDTAPVQEVIRsgRNGLLVPFFdTDALAETIVGALNrpdn 371
gi 159178989 289 PYDYYLRVLRVSRVHTYLTYPFVLSWSMLESMSTGCCMVASSTPPVCEVMRdgETGALVDYFdGEAMVDRICTLLDdpet 368
gi 66046317  290 SYAKYKQVLSLSSVHVYLTYPFVLSWSLLEAMAMGCVVLGSKTKPVEEVVTdgINGYLVDFFdSSNIADQTLLILNsldk 369
gi 161787838 296 EYDVFRALLRRSDAHVYLTYPFVASWSLREAMAMGCAIVGSDTAPVREFLSdgRTGRLVPFLdPDGIAAGVLEVLEdral 375
gi 66968576  289 DYATYRTALQVSAAHIYLTYPFVLSWSLLEALACGCPVIASDTAPVREVIQdgVNGWLVGFFdKDALVGHMLELLAnq-s 367
gi 32456021  330 PYAQLCKIIQLSRCHIYLTMPFVLSWSLLESMAMQATIVAADVAPVREAIShgETGLLVDFFdPSALAAQVSEVLArpqe 409
gi 33632254  298 PYEQFLLLLQLSACHVYLTYPFVLSWSLLEAMACGCAVVGSDTAPVREVIRhgINGLLVDFFsPADLASAVSELLRdrdr 377
gi 78483937  298 PRDEYVRTLQASHAHVYFTEPFVTSWSLSEAMATGCLVIGSNTAPVRELVRdmENGLIVDMDdADEVADAMAWVLDnpgd 377
gi 33337561  298 NYGELVQLFRRSDLHCYFTRPYVVSWGVFQAVACGARLLVNDFAGIDEVFDgkPFFSPVDLDhQEQINASVIECLRveke 377
gi 39982859  287 PHDQFVRYLQAMDVILFPLFEGAANWGLFEAMAAGVPVIASRRCFIPEVIEdgRDGILLDAAdAEGFAAAALALLEdsar 366
                        410       420
                 ....*....|....*....|....*...
Feature 1                                    
gi 1890594   372 FRELRGAARRtveq-rfrlDDCLARQLT 398
gi 159178989 369 RSRYSAAARDyavqnydleTVCLPKQIA 396
gi 66046317  370 QESIKRNARNtaya--yssDKANAAYWH 395
gi 161787838 376 ATRLRRAARRqaer-tldmGEYMARYRD 402
gi 66968576  368 NNFMRREAISqsvkvrysvAQGVKEYLE 395
gi 32456021  410 YAHLGVNARAhvvenydflTRCLPEHIA 437
gi 33632254  378 AASFGAEARRtver-sydlDVCVQRQLA 404
gi 78483937  378 AADLRRAARRtiladhdaaRVFPAKDAW 405
gi 33337561  378 SNAVSLPSSLslss--ciaQWVDLIFSM 403
gi 39982859  367 AEAMSRAGRQkiar-sfsvERAASGYAA 393

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