Conserved Protein Domain Family
GT4_MtfB-like

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cd03809: GT4_MtfB-like 
glycosyltransferases MtfB, WbpX, and similar proteins
This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Statistics
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PSSM-Id: 340838
View PSSM: cd03809
Aligned: 76 rows
Threshold Bit Score: 159.836
Threshold Setting Gi: 586605
Created: 6-Dec-2005
Updated: 9-Jun-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21240815    2 HIILATESIrh----plTGVGRYTQELAAHLaa--------------lPQIESLQYLHGRRllqqrpspgpasaaasw-- 61
gi 91200935   13 TCHIAIYLVahp---smGGTFQYTLTVLKAFakik---------ennrNGVSILCITLTKDwndllkkdypqfsvthihr 80
gi 42527052    2 KIGVDAFGCdh----grSGIGSYILSIVKNLpk--------------nDYEFELFGPELDKytytsdidyvsftgi---- 59
gi 161330534   4 RLIFSACGFdc----gkSGISQYMQNVVAELlk-------------shHVTVLINNSDQPFwpiehprqtlvvlp----- 61
gi 46581398    2 RIGICIQWGve----gwTGGINYLRHLVLGAaslp----------prlRPRIVLLFEAAQAaalplyesivpl------- 60
gi 27381117    6 PLRIAFTNIprr---lwAGGYNYQRNLFAALhryspgtvapvlfagtrDDPEELAALASIPavalvr------------- 69
gi 32471993   18 IGIINYSHSd------wQGGRNYIQNLLTALqt-------------ldADSLNFEVVEVPShesksnsvltrl------- 71
gi 15832094   32 EICIDILLPrndihsliREKAFPFKSILKAIl---------------kRERPRWISLNRFNe------------------ 78
gi 29348274    7 TIVVSAVSLrkg---gtLTILQDCLCYLSALaa--------------dGNYRVIALVHKREladyphieyiem------- 62
gi 29345464    7 LIVVSAVGLr------qGGTLTILKECLQYLstc-----------vreGHVRVIAIVHDRRlaefngieyiel------- 62
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21240815   62 --------mrdrfsrievatdayrrLSNLAKARALhgq--------------rpALFHGCNYYlp-------ayDGPSVA 112
gi 91200935   81 nifhkavgkvlkstkfgwfvwrkinKLLPFAYKDIfkm--------------nlDLILYPSQDdiv-----heiDIPAIS 141
gi 42527052   60 -----------disdtkfsekiwhfKNLNSFIKKQr-----------------yDAVIYPAGVe----------LLPPIF 101
gi 161330534  62 -----------wylnhpianmvyhtWILPHSLKQRlktn------------hydALILPAANRrvl-----shyPLPTVA 113
gi 46581398   61 -------------adevrvmhgtrdAAGVYHVHDPetvf-----------agldIAYPLPHGFadv------psGLPRLF 110
gi 27381117   70 -------------------spafdrSATGLLGALAlgrdgpa-----laefraqGVDIVFESArffg----wrlPCPAIA 121
gi 32471993   72 -------------knrfhtirgihqPQLHAELVKQ-------------------GIDFAYYCAtgdr----ekvGYQSAH 115
gi 15832094   79 ------------------------qYYRDAFTQNNietnltfikskssafysyfDSSDCDVILpcmrvpsgnlnKKAWIG 134
gi 29348274   63 --------------pdvikgwgrrlWCEYVTMYKLsqki------------mpvYLWLSLHDAtpr------vvAERRVV 110
gi 29345464   63 --------------pdvikswtrrlWCEYITMHRIsqrl------------pgiDLWLSLHDTtpr------viAKRQAV 110
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21240815  113 TFHDISIYRWPQCHrad-------rvrYMRKELALAVQRAQLILTVSDFSRREIAAHFal--------------pLERIR 171
gi 91200935  142 VIHDLMHRYEKQFPescsi----qeieRRERQYKKICKFSTIIIVDSKVGEKQVEESYg---------------nILKAK 202
gi 42527052  102 TVPSILVIQSLLSAdl---------gtIAKMGLRRTLKNASGLISPTKYIQNDLSQFGv---------------nASDIK 157
gi 161330534 114 TFHDLSQCYIANKYdilrmh--yirhlIPKFLQPIASPYRPHLIAVSDNTRKDMETFLhi--------------pAHHIS 177
gi 46581398  111 WIPDFQHRHLPRFFper-------elaERDALFSAIGRSADVVVLSSEAARRDVMAFYgv--------------pRERTF 169
gi 27381117  122 WFPDFQHRLLPHLFsrs-------aywRRDLGFRAQIASGRHIMLSSASALGDLKRFYpg--------------iSNGVS 180
gi 32471993  116 WIADFQSLVRPEFSpdd-------ysvKAQSYFRSVLRDSQQVVLSSNASQNDCRKLFpeyvs-------ktavlPFRVA 181
gi 15832094  135 YIYDFQHCYYPSFFskr-------eidQRNVFFKLMLNCANNIIVNAHSVITDANKYVgnysaklhslpfspcpqLKWFA 207
gi 29348274  111 YCQTSFPFYKWSWRdflfdykivlfalFTRWIYRINVHRNTYLIVQQEWLRSGLSRMLgv--------------kKEKFI 176
gi 29345464  111 YCQTSFPFYKRTWRdfyfnykialfslFTRYAYRINVHRNQYMIVQQSWLREGLSRMLgv--------------gKEKFI 176
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21240815  172 AIPLAADaafrphaqaela--aplqalglqtdAYCLCVSTIEPRKNIDVLLTAYAALPAavr--aryPLVIAGHSGWSse 247
gi 91200935  203 VIPLPFIpppyilehnptidftyviekyklhsKYVFYPAQFWTHKNHHNLLKAIDLLKDkgi---kvNAVFVGSKKNNyk 279
gi 42527052  158 VIYNGIDcslfkpitnded-rvliqpfaiqrpYIIYASRITHEQKCHVELIKAFALFKKqtg--sphRLVIAGSDGNNse 234
gi 161330534 178 VLHNGYDkslfneqqprdl-aqrlkrlqlkpdYLLYVSRIEHPGKNHIGLIQAYEKLPEtir--nkhPLVFVGSAWSGae 254
gi 46581398  170 VLPFCTVgeedwyagdva----avqarhgiapGYLMCCNQFWAHKDHLTLFRALARLRAegg---vpQLVCTGGTDDYrd 242
gi 27381117  181 VVRFATEppvsllatkps----dviaqyglpsRYFYLPNQFWRHKNHQVVVDALGLLKGrg-----iDVVVAASGSTRdf 251
gi 32471993  182 TFPQLIEqslpslpel--------kkrfdlpdKFFIVCNQFWAHKNHETIFKAVEMLSKkn-----kSTCVVCTGQWKdl 248
gi 15832094  208 DYSGNIAkyn-------------------idkDYFIICNQFWKHKDHATAFRAFKIYTEynp---dvYLVCTGATQDYrf 265
gi 29348274  177 VAPPERKendviae------------ivelscFTFFYAATPDCHKNFELLCDAASLLEQelgkgrfkVVLTISGQENKya 244
gi 29345464  177 VAPPRRMavkvete------------svnlpcFTFLYASAPDCHKNFEVLCQAARLLEKekg--kgcFKVVVTLSGKEnr 242
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21240815  248 alha-------rmrsaeQAGWLRYLGYVpQDGLPALVAgARLFVFPSFYEGF--GLPVLEAMASGTPVICASa-sSLPEV 317
gi 91200935  280 nvid-------linilsLGEQIRIIDYVpNEDIVALYKnSIALVMPTFFGPT--NIPIVEAMFLGVPVICSNv-yAMQEQ 349
gi 42527052  235 avhn-------aviqsgFSSDILLTGYFpHESLPQLYSsADLCVFPSMIEGV--GLPVIEAMACGVPVACARa-gALPEV 304
gi 161330534 255 vvfk-------riadspAANSIRVLGFVdSSDLPSLYHgAATTVMPSLYEGF--GLPLVEAMACATPVACSNr-gAMPEV 324
gi 46581398  243 pkhfpml--lraldrlgIAEQVRILGLIdRRDQIQLLRgADAVVQPSLFEGW--STVVEDARALGKTIVLSDi-dVHLEQ 317
gi 27381117  252 repdlfertmsevrsrgLETNFRHLGMIpLDHVYALLRaSMALINPSECEGW--STTVEEAKSFGVPMILSDi-dVHREQ 328
gi 32471993  249 rnrnhqetidrllekpsIKQGIRLVGKIpFDSLLGLIRhSHAVIQPSHFEGW--NTSVEESHCLGKTILLSDi-pVHREQ 325
gi 15832094  266 pgyfnel--mvlakklgIESKIKILGHIpKLEQIELIKnCIAVIQPTLFEGGpgGGVTFDAIALGKKVILSDi-dVNKEV 342
gi 29348274  245 qwl---------ykkfgSVSSIEFAGFMsREKLFGYYHaVDCLVFPSKVETW--GLPVSEFMATGKPMLLADlpyAHETA 313
gi 29345464  243 ytrw-------lyknwhDVNSIEFAGYMnKEKLYGYYQaAHCLVHASKVETW--GLPISEFGETGKPMLLADlpyAHATA 313
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21240815  318 AADAAMLFDPa-dVSALTLALARg-----IDDSDWREAARQtgl------qrAAQFSWQRCAVATAD 372
gi 91200935  350 VGNAGLLFDPk-sINGIADSIYRi-----WTDENLRKGLIQrgy------kkVKNITIENYTKQWEN 404
gi 42527052  305 AGDSALFFNSk-kPEEIAEAISSlv--dcDKNTAKRKEIIEkgl------dwVKKYNWETTAHQTIE 362
gi 161330534 325 VGEAALCFDPe-sSTSIAQCLGKi-----LTQPSFQQELIRrgl------erVTAFDWGVHTRMLLN 379
gi 46581398  318 DPPHGHTFRAg-dPADLARALQEaqgdftPTAGTERETEARadnaerllrfgMGLVHLARAAQEARP 383
gi 27381117  329 TEGSARYFGIr-dAEALAAHLSEva--qsADPPTIRDLLPDle-------erVKAFVADFVRLTADV 385
gi 32471993  326 ACPTAQYFDPt-sYESLAKLMCNsldeatTGFDAGREQMAVdrytv-kikefARAFLNLATQSQHNH 390
gi 15832094  343 NCGDVYFFQAk-nHYSLNDAMVK------ADESKIFYEPTTli--------eLGLKRRNACADFLLD 394
gi 29348274  314 AGSMQTAFFKlsdPVQLMNLMKRl-----CEDDFTFLTSIGt---------sDKRFSFASSWRELFD 366
gi 29345464  314 SGFHAVGYFNehkPEELKRLMKE------MLEGDHRSLSSQpsta----ikgLYVCSWRELFEKLLP 370
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