Conserved Protein Domain Family
GT4_WbnK-like

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cd03807: GT4_WbnK-like 
Shigella dysenteriae WbnK and similar proteins
This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.
Statistics
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PSSM-Id: 340836
View PSSM: cd03807
Aligned: 17 rows
Threshold Bit Score: 318.107
Threshold Setting Gi: 21221166
Created: 23-Jan-2006
Updated: 9-Jun-2017
Structure
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Aligned Rows:
 
putative
Feature 1:putative ADP-binding pocket [chemical binding site]
Evidence:
  • Comment:Some of the residues involved in ADP binding bind indirectly.
  • Comment:Based on similarity to sequences with known structure

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                      #                                                                 
gi 40950668   16 KVVHIIIDLNv--GGAELMLQRLIKHta-dNNVEHVVISLTDIGTLGEEILk-sGVDVKCLNINsp----------ikYA 81
gi 161167785  20 KVAHVVLSLNv--GGLERVVLRLLDRma-rDRFAPVVCALQEPGALAEELAr-lGVPLVVLSRKpg-----------lDP 84
gi 29654167   14 CIVVAINALDv--GGAEKHLLRVLPSlk-kRGYNIILYLTNHRGVMFDEMLa-aGIPIITPPLCeflnklgplgkpfiYS 89
gi 16264482    1 MIMHVITNFTa-sAGAETMLARLLHGa---TDERVVVVSLIGVSERNRRLAdnpRVAYVSLGAAsl----------taLP 66
gi 32474317    2 KIALVIPTMDr--GGAEKQVVLLAKGlh-eLGHDVRVFLLTRDGHRSEDLRa-aGVPVVLIGKRfk-----------mDP 66
gi 39997055    2 KIAYVIDYLYsvnGGTERQLYMLIEGm--vSRGHTVDLYVFRDTEFTKNLPd-fPCPVHCLNVEsv-----------lSP 67
gi 15643387    3 KVLHIIPSLAv--GGAEKLVSDMVEFad-rSRFDVAVMRITGTDSFLVEKLtskGYQVYTIVLDyeai------apskVI 73
gi 21221166    2 KALHIITGLGv--GGAEQQLRLLLRH----LPVDCDVVTLTNPGPVAEGLLa-dGVHVVHLGMTgn-----------rDL 63
gi 46578975    2 KVAYVIGGLPf--GGVESWLLDLARHvsktSDFECRVFNVSGTGVKMPEYIs-sGVDVVCAGNSldsi-------athRI 71
gi 32474664   13 NCMFIITSMPv--GGAETLLVNLMRRmd-pNLIRPEVVCLKEPGPLGTEIAnefPIHSHLIGGKy-------------DV 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 40950668   82 TSLLKLYKLFt---KIKPDVVHTWMYH-------SDLIGGISAKLa--------GVKKIIWCVRSTDISkg-gnKLTLLI 142
gi 161167785  85 GLPLRLSAWLr---REGIALVHTHNPG-------PHLYGALAAGLlraaalpggGGPRVIHTKHGRNYP-----KQKRKV 149
gi 29654167   90 LSIIRLSFLIl---KRNPSILHFFLPG-------TYVLGGISGLLa--------RARCMVMSRRVTNEYq----KTHPIV 147
gi 16264482   67 GAVLRLARLIr---KEQPDVILCWMYH-------AMVAGTLAAGMa-------rHGAPVFWNVRQSLDDpasltRSSRVA 129
gi 32474317   67 TALFRLKKQLv---DFAPDIVHTWLFA-------ANSFGRVAAKW---------AGVPVIIASERCVDP-----WKTGWH 122
gi 39997055   68 GGLIRLIQFRkriiADNVDVLHGFFND-------VALSLPPLMLG---------SNVKTFTSRRDMGIW-----YSPAKL 126
gi 15643387   74 RRLLRAIKNM----RRTYNLLREIRPDiihshlsALRIALIPALLc--------RIPVKVHTIHTVAEK-----DAKGIT 136
gi 21221166   64 AALPRLARLIr---TGGYDLVHTHLYR-------ACLYGRIAARLa--------GVRAVVATEHSLGDSqmegrPLTPGV 125
gi 46578975   72 DTVLRLRSQLv---EYAPDIIHTLHFS-------GDYCGRLASIG---------LGVPVVTHLRNIKCE-----RKLRRR 127
gi 32474664   77 AVLPRLARLMr---KRKADAVITVGAGd------KMFWGRLAAKM---------AGVPVIASALHSTGWp----DGVGRL 134
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                    ### 
gi 40950668  143 RWLCAKISSFIPDtiVYAANASKEVHEQc-GYDKNKSLVIANGFDLTKLSPDkfsrsdlr--keiglaeNDVVVCSVGRY 219
gi 161167785 150 LVNRLAAALTDRV--VAVSDDARAVALEveHVDPAKVVTILNGVDTDVFRPGdagaara----rlgvpaSGYHVGCVARL 223
gi 29654167  148 AKIEPLLHKYMKVv-LATSLRVGTELLEe-GVPPNKLGLIYNGVEVEKYNIHynkpaik---rsfclgdDTFIIVILANL 222
gi 16264482  130 IAAAKLLSHRPAGi-IYNSARALELHRAy-GYANRNAVVIPNGFDLPQLAAPep--------------rTARRIGIVGRF 193
gi 32474317  123 FLIDRRLQKISQAi-TTNSSGVQDFYAAn-GLDPAQFVVIPNGVESIDSTKTqaidreea-frrlevasERRLIVAVGRL 199
gi 39997055  127 LFLRLFRFSSIRL--ICNSIAVAKFTFEqeWKAKESIRVIYNGMNRFNVDPSscscdw------apekgKNINIILVANV 198
gi 15643387  137 RFFNRIAFKFFGFvpVSISQEVAESVKKl-YGRKISTPVIYNGIDVQKFSIDqpkr----------vdrDKTILINVARL 205
gi 21221166  126 RALYLAGERLGSAt-VAVSPTVADRLQRw-GVPAPRIEVVPNGIDLARFRFDpvrrlrtr--rrlglpeGAYVVGGVGRL 201
gi 46578975  128 LANKLLSFFTDMY--LSVSRAVADMVADdhNIAKRPSRVIYNAVDPQKLAVEphdlt-------amygvSGRIVVGVGRY 198
gi 32474664  135 NRLLTHITDAFIG--VAESHGEFLRTFE--KFPANKVNVIRNGIDCDRFHPSaecrtspnvreelglaeETPLIGIVAAL 210
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                #       
gi 40950668  220 SpVKDHSTFISAALQLaee--fsnVRFLLVGRGLTTQNKIImtql-svsCHSDKFILLGe---------RSDVPACLNAS 287
gi 161167785 224 SpEKDHATLLDAFARLrat--rpdAHLTLIGDGPRRPALEAqaa---rlGLGGAVTFTGt---------RGDVAELLPAF 289
gi 29654167  223 YkRKGHKDLFYALSSIkeki-sknWKLLCIGRDGGEKNALEslr--dnlGLREYVTFLGq---------QHDIPQLLSIA 290
gi 16264482  194 HpQKDHGTFFKAAAQVvkt--hpqAVFSAAGNGLVRDNPAVielmtqagLPAHSVDLRGe---------ISDMPAFYQSI 262
gi 32474317  200 WpQKRIRDLIWAGELLata--rgdTTLVVIGDGPQREELLRhrd---svSAPLHVRFAGq---------REDVGELLPHA 265
gi 39997055  199 RpVKRVEDLIRAASLIvehgyhpqYYVVGHLQSDGYTDSLRell--krhHLEADFHFTGp---------VSEPRGALERF 267
gi 15643387  206 SrEKNHALLVRAFSKAvqs--cpnLELWLVGDGELRRDIEElvk---qlGLEEKVKFFGv---------RSDVPELLSQA 271
gi 21221166  202 AaAKRFDVLVRALALLpp-----dCWLLLVGGGPEEHLLRRtar---eaGVADRVLLTGerpclpdgspGPDLPALAAAM 273
gi 46578975  199 VgQKNFDLLLRALRLVlde--ghdISVVLVGEGGERPHLERlir---elSLEGHAVLTGy---------RQDVPRFLRAS 264
gi 32474664  211 RsEKNHSMLVHAAAKLrdr--hpdLHTLVIGEGPERATIEPlie---elGLTDRVHLLGn---------RADTPRLLGAM 276
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                      #                                                                 
gi 40950668  288 DIFCLHSVTEGFPNVLGEAMAMGIPSVTSNVGDAAFLLDk--vDFVVPAGN-SYLLAQKLREVILls-----rkNRTKLG 359
gi 161167785 290 DVFALASLTEGISLTLIEAAAAGLPIVATRVGGNPEIVVdgetGMLVPPGA-PETLAGALEAVAVr-------eDRAEMG 361
gi 29654167  291 DMGVLSSHEEGFSNALLECMAAGLPMVVTDVGGNAEAIVdkqcGFVVPPKQ-PQQLAEALLMLALdk------eTRDKYG 363
gi 16264482  263 DLLVLSSRTEGFPNVIAEAMSFGKPIVTTDVGDAAAVAGk--aGIAVPARD-PQALADAMRAFLDlp-----eaEYARYA 334
gi 32474317  266 DQFWIASEYEGQSNAVIEAMLAGVPVIASNIPGNRDLVIdketGWLFDVGD-EADLVRLSLAAFNdp------dGSQRIA 338
gi 39997055  268 DIGVLTSASEGFSNTLMEYLDAGLPVVASKVGGNPELVDdgetGFLYEAGD-VNALADCILKLIAd--------DRTRNL 338
gi 15643387  272 DIFVLSSDYEGFGLVVAEAMAAGLPVIATAIGGIPEILEggraGILVPPKD-VDALAKAIVELARde------kKRAELS 344
gi 21221166  274 DVLASPSPEEAFGLAAVEGLASGLPVLYASCPAIEDLPP----EAAPTARRvTGGAAEFARALAEtrashgpvpGMRTAP 349
gi 46578975  265 YALAMPSDFEGLPITHLEAMFCGLPAIVSRHVPSLEIARe---ASLVCKRS-PESIAQCIIRLLEd-------eKLHSTL 333
gi 32474664  277 NVFTLCSLNEASPVSILEALACETPVVATDVGSISETVLpgqtGELVPSED-VQSFVAAIDMLLNda------dQSSQLG 349
                        410       420
                 ....*....|....*....|....*
Feature 1                                 
gi 40950668  360 RILRLRIENEFSm-DTVANKYLSLY 383
gi 161167785 362 LRGRARVMERFGidRMARAYEDLYD 386
gi 29654167  364 NAAKERVKKYFSleACVLRYDQFYE 388
gi 16264482  335 RTARERIENEYAiaAVTTKYSEFLM 359
gi 32474317  339 EQARQHIVDEFSldAMIRRHVMLYE 363
gi 39997055  339 FAANAKQMITRF--DRATMIESHEK 361
gi 15643387  345 DYGRKLVAERFDirRTVREYEKLYL 369
gi 21221166  350 EAARHYCVTRSAa-RLMDVYATALT 373
gi 46578975  334 SNTGSRIASEHTmdLYIKTLKGIYD 358
gi 32474664  350 RNGRELVQATGSlqSMVDGYQTLVH 374

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