Conserved Protein Domain Family
GT4_sucrose_synthase

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cd03800: GT4_sucrose_synthase 
sucrose-phosphate synthase and similar proteins
This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.
Statistics
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PSSM-Id: 340830
View PSSM: cd03800
Aligned: 24 rows
Threshold Bit Score: 457.858
Threshold Setting Gi: 17134123
Created: 6-Dec-2005
Updated: 9-Jun-2017
Structure
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Aligned Rows:
 
putative
Feature 1:putative ADP-binding pocket [chemical binding site]
Evidence:
  • Comment:Some of the residues involved in ADP binding bind indirectly.
  • Comment:Based on similarity to sequences with known structure

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                  #                                                      
gi 401114     177 YIVLISVHGLVRGenmelgrdsdtGGQVKYVVELARAms-------------mmPGVYRVDLFTRQVSSpdvdwsygept 243
gi 73808808   166 YIVLISLHGLVRGdnmelgrdsdtGGQIKYVVELARAla-------------lmPEVYRVDLLTRQICSpdvdwsygept 232
gi 32398248    10 RVTLLSLHGLIRArdcelgrdadtGGQVKYVLELAEEls-------------rrEEVESVELVTRQIFDervgpdya--- 73
gi 22298125     6 YIVLISIHGLIRGdrlelgrdadtGGQTRYVVELAKTla-------------ahPRVAQVDLVTRLIPDakvspdya--- 69
gi 39841338     8 YIVLISIHGLIRSqnlelgrdadtGGQTKYVVELAAAla-------------qhPDIEQVDLITKQIIDpkvsadyg--- 71
gi 17134123   272 RIVLVSAHGWFGQegvlg--rpdtGGQVVYVLDQAKNlekqlqedailaglevlNVQPKVIILTRLIPNsdgtlcnq--- 346
gi 156270676   21 RIALISTHGYVAAhpplg--aadtGGQVVYVLELARKl---------------gQLGYTVDLYTRRFEDqpef------- 76
gi 10177148   275 NVVILSPHGYFGQanvlg--lpdtGGQVVYILDQVRAlenemll---riqkqglEVIPKILIVTRLLPEakgttcnqrl- 348
gi 33241329    10 LHGLIRSHDLELGrds------dtGGQTLYVLELVKEla-------------asLEVDQVDLVTRLIQDrrlasdys--- 67
gi 310947088    7 RVAMLSVHTSPLEqpgt----gdaGGMNVYITELSRAl---------------aRSGAEVEIFTRRTSSaqpdv------ 61
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 401114     244 eml-cagsndgegmgesGGAYIVRIPCGPRDKYLKke-----alWPYLQEFVDGALAHILnmskalgeqvgngrpvlpYV 317
gi 73808808   233 emlslgsyddfedvgesSGAYIVRIPCGPRDQYLRke-----llWPYIQEFVDGALTHILnmtkvlgeqigsggliwpHV 307
gi 32398248    74 ----------qveeiinPKAKIVRVPFGPKRYLRKeg------lWPYLETFIDQMLGHYRrvg-------------lpDL 124
gi 22298125    70 ----------qpierigDRARIVRLACGPRRYLRKev------lWPYLDVFADELLRYLRqsg------------rmpDV 121
gi 39841338    72 ----------qscepisEKANIIRISAGIDDYIPKee------lWDYLDNFADNTLTYLNhqp------------rlpDL 123
gi 17134123   347 ---------rlekvygtENAWILRVPLREFNPKMTqnwisrfefWPYLETFAIDSERELLaefq-----------grpDL 406
gi 156270676   77 -------------devdERVRVVRIPCGGRDFIPKey------lHRHLMEWCENALRFIKknd------------lnySF 125
gi 10177148   349 -------ervsgtehahILRIPFRTEKGILRKWISrf-----dvWPYLETFAEDASNEISaelq-----------gvpNL 405
gi 33241329    68 ----------rpreriaPSANIIRIPFGPKRYLRKel------lWPYLDQLVDQLIDQLKqak------------tlpDW 119
gi 310947088   62 -------------vevgDGILVRHITAGPFEGLDKnd------lPGQLCYFSAGVLRTEAartq-----------gwyDV 111
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 401114     318 IHGHYADAGDVAALLSGAlNVPMVLTGHSLGRNKLEqllkqgrmskee-----idstykimrriEGEELALDASELVITS 392
gi 73808808   308 IHGHYADAGDIASLLSGAlDVPMVLTGHSLGRNKLEqllkqgrqskhd-----inatykimrriEAEELSLDAAELVITS 382
gi 32398248   125 IHGHYADAGYAGAQLARLlHVPYVFTGHSLGRVKRQrliaasqeskapkppreldkkfkftvreEAEEFALETASMVITS 204
gi 22298125   122 IHSHYADAGYVGCRVAGWlGVPLVHTGHSLGRVKRQrllaqgskpda------ieeqfhlttriEAEEQTLASAALIIAS 195
gi 39841338   124 IHSHYADAGYVGIRLANHlGIPLFHTGHSLGRSKRKrllasgvkgeli-----esryrltrrinAEEETLASATRVITST 198
gi 17134123   407 IVGNYTDGNLVAFLLTRRmKVTQCNIAHALEKSKYLfsnlywqdle---------ekyhfslqfTADLIAMNAANFVISS 477
gi 156270676  126 INSHYWDAGVAGQRLSEAlKIPHLHTPHSLGIWKKRqmetdypekadt-----felefnfkeriQHELIIYRSCDMVIAT 200
gi 10177148   406 IIGNYSDGNLVASLLASKlGVIQCNIAHALEKTKYPesdiywrnhe---------dkyhfssqfTADLIAMNNADFIITS 476
gi 33241329   120 IHAHYADAGYVGALVSSRlGIPFVFTGHSLGREKKRrllesgmdhlq------ientysisrriGAEELALANANLVVTS 193
gi 310947088  112 VHSHYWLSGQAGMLAADRwNVPLVHSMHTMALVKNGslapgdv--------------pepagrvIGEEQVVEVADALVAN 177
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 401114     393 TRqeideQWGLYDGFDVklekvlrararrgvschgrymprMVVIPPGMDFSNVVVhedidgdgdvkddivgleg------ 466
gi 73808808   383 TKqeieeQWGLYDGFDVklervlrararrgvschgrymprMVVIPPGMDFSNVIVqdtgdvvddgeavqitssdsssvvp 462
gi 32398248   205 TGqeveeQYAVYDHYQPd---------------------rMEVIPPGVDLDQFYPvdeseplpri--------------- 248
gi 22298125   196 THqeveeQYRLYDQYDPa---------------------rMAVIPPGVDTSRFYPapvpadlpf---------------- 238
gi 39841338   199 QQei-qgQYAQYDFYHPe---------------------nMRVIPPGTDLQCFYPptgdewqgsv--------------- 241
gi 17134123   478 TYqeivgTPDSIGQYESykcftmpelyh-vvngielfspkFNVVPPGVNENSYFPytqtqnriesdrdrlee-------- 548
gi 156270676  201 TPvqldvLIEDYGLKRKh----------------------IHMIPPGYDDNRFFPvsdatrq------------------ 240
gi 10177148   477 TYqeiagSKNNVGQYEShtaftmpglyr-vvhgidvfdpkFNIVSPGADMTIYFPysdkerrltalhesiee-------- 547
gi 33241329   194 TFqeaneQYSRYKNFVSk---------------------qAKTIPPGVDLRRFNTiskpnefeev--------------- 237
gi 310947088  178 TAaeaedLVTHYAADPTr----------------------VHVVSPGVDLETFTPlppagadgard-------------- 221
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                    ###                                                  
gi 401114     467 aspksmppiwaevmrfltNPHKPMILALSRPdpKKNITTLVKAFGECrpl-relANLTLIMGNRDDIDDmsagn--asvl 543
gi 73808808   463 vspranppiwdeimrfltNPHKPMILALARPdpKKNLTTLLRAFGERral-relANLTLIMGNRDDIDEmsngn--aavm 539
gi 32398248   249 ---------hdlltpflkDSEKPMVVAMARPdeRKNIEMLVRVFGENpkf-remANLVLVLGSRDDLREmpsgq--rrvl 316
gi 22298125   239 ---------rqelrrflvEPEKPFIFCLSRPvpRKNVAALLNVYGSDrfl-qarANLVLVLGNRTDISKmeasp--rqvl 306
gi 39841338   242 ---------wqklavflqEPRKPMILALSRLdqRKNILGLIRAFGTSpsl-qqqANLVVFSGTRDDPRDlssna--qaif 309
gi 17134123   549 --mlftledssqifgkldDPNKRPIFSMARLdrIKNLTGLAECFGQSqel-qerCNLILVAGKLRIEESednee--kdei 623
gi 156270676  241 ------------mirqrfGFEGKVVLALGRLatNKGYDLLIDGFSVLaer-epeARLHLAVGGENMDEQettilnqlker 307
gi 10177148   548 --llfsaeqndehvgllsDQSKPIIFSMARLdrVKNLTGLVECYAKNskl-relANLVIVGGYIDENQSrdree--maei 622
gi 33241329   238 ---------qdlfapflrKPNLPPLLAISRAvrRKNIPALIEAFGRSpll-rqkHNLVLILGTRTDMKLldkqq--kdvf 305
gi 310947088  222 -------taaaeraalglPADRKVVVFAGRVqlLKAPDVLVRALGVMadhgdelPLLVVLGGASGRPTAlrel----eal 290
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                    #                         #                          
gi 401114     544 tTVLKLIDKydlyg-svafPKHHNQADVPEIYRLaakmKGVFINPALVEPFGLTLIEAAAhGLPIVATKNGGPVDITNal 622
gi 73808808   540 tTVLKLIDKydlyg-qiayPKHHKQSDVPEIYRFaaktKGVFINPALVEPFGLTLIEAAAhGLPMVATKNGGPVDIHKal 618
gi 32398248   317 tNVLHLIDVydlyg-hvayPKAHRPSDVPELYRLtarrKGIFVNPALTEPFGLTLLEAAAsGVPIVATNDGGPRDIIAnc 395
gi 22298125   307 mELFLLVDRydlyg-kvayPKTHRSDEVPDLYRLaaqqRGVFINPALTEPFGLTLIEAAAcGLPILATADGGPQEIIRhc 385
gi 39841338   310 tELLWAIDRynlyg-kvayPKFLSAQEIGELYRLaslsQGVFVNPALTEPFGLTLIEAAAsGLPIVATEDGGPVDILKnc 388
gi 17134123   624 vKLYRIIDEynlhgkirwlGVRLSKNDSGEIYRVicdrQGIFVQPALFEAFGLTILESMIsGLPTFATQFGGPLEIIQdk 703
gi 156270676  308 vKSLGLEDKva-------fSGYVADEDLPDIYRA----ADLFVLSSRYEPFGMTAIEAMAsGTPTVVTIHGGLFRAISyg 376
gi 10177148   623 qKMHSLIEQydlhgefrwiAAQMNRARNGELYRYiadtKGVFVQPAFYEAFGLTVVESMTcALPTFATCHGGPAEIIEng 702
gi 33241329   306 qQIFELVDKyqlyg-qvayPKFHRRDQIAPIYRWasklEGLFVNPALTEPFGLTLLEAAAcGLPMAATDDGGPKDILSsc 384
gi 310947088  291 aYQVGVSDDvl-------fLPAVSRSELARWFRC----ADLVAVPSRSESFGLVAVEAQAcGTPVVAADVGGLRTAVQdg 359
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
Feature 1                                                                       
gi 401114     623 nnGLLVDPHdQNAIADALLKLVAd----KNLWQECRRNGLRni-----hLYSWPEHCRTYLT 675
gi 73808808   619 snGLLVDPHnEKEIADALLRLVAd----RSLWNECRKNGLKni-----hLFSWPEHCRTYLS 671
gi 32398248   396 qnGLLIDPLsAEDIDHALMRCLTe----PEQWQTWSENGIEgs----rtHYSWANHVDRYLR 449
gi 22298125   386 rnGLLFDALdLEAIRSALHQAFQs----DSQWQTWADNGLKgv----qaHYSWHSHVEMYLQ 439
gi 39841338   389 qnGYLVNPLePQNIAAKISKILGd----AQRWQTFSQQGIRnv----rrVYTWQSHVERYME 442
gi 17134123   704 inGFYINPThLEETATKILDFVTkceqnPNYWNIISEKAIDrv----ysTYTWKIHTTKLLT 761
gi 156270676  377 rhALFADPFdKEDLGITMMKPFKh----ERLYGRLSRMGAHka----rsLFTWTGIAQQLLA 430
gi 10177148   703 vsGFHIDPYhPDQVAATLVSFFEt----CNTNPNHWVKISEgglkriyeRYTWKKYSERLLT 760
gi 33241329   385 rnGLLFDATdLDVLQNTLELAGSn----KKLWQQWSSRGIDgi----kkYYSWNSHVSKYLS 438
gi 310947088  360 rsGVLVPDHdPHRWAAVLRDLLRd----DERLARLSRGALEva-----aHFSWDTTAEETRK 412

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