Conserved Protein Domain Family
Endoglucanase_E_like

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cd01831: Endoglucanase_E_like 
Endoglucanase E-like members of the SGNH hydrolase family; Endoglucanase E catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
Statistics
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PSSM-Id: 238869
View PSSM: cd01831
Aligned: 31 rows
Threshold Bit Score: 100.111
Threshold Setting Gi: 48865754
Created: 17-Aug-2004
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
Feature 1:active site [active site]
Evidence:
  • Comment:the active site resembles the typical Ser-His-Asp(Glu) triad from other serine hydrolases
  • Comment:the histidine side chain is oriented by a backbone oxygen or an aspartate/glutamate side chain
  • Citation:PMID 7773790

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1               #                                                                        
gi 121827    605 KIEFIGDSITCAYGNegtskeqsftpKNENSYMSYAAITar-nlNASANMIAWSGIGltmnyggapgplimdry------ 677
gi 48870801  138 LVAFIGDSITAGCWVrsk-----apsIGYGADLNYAAQLsr-alDWEDYRIAYSAAGiirygtggvppagkf-------- 203
gi 40744082  152 KVEIIGGSASLTGGQy----------ATYETLSAWSFVYaqglgNVEFGITAYPGAClvdmqcygggvhgmiwywhrasd 221
gi 115387605  85 TVEIIGDSLAAGQYAty--------eGLASWAFNFAAGLg----NVEYSITAYPGIClvdqkcyggtargmthqwlqipd 152
gi 23024922  121 YITFIGDSITAGEEMi---------eHEPHPELSYPELIae-mlHKPLARIGYGGSGltpsapfqeptavea-------- 182
gi 70988681   65 MVEIIGDSPIRVSASttr-----iagETPVVRYARASIVvfptdHQAYQWYRTSDTSwraheiygdnp------------ 127
gi 28272603  136 SVTWIGDSLTAGCWVmgk-----npaEDYRAEANYAAVAsd-llNARNVRIAYSAVGlskpgtggvpvlpev-------- 201
gi 40743290   63 EQHISWWSALSNECSlss-----gdfATYEGLSSWAYLFaaglgNVEYHLTAYPGIClhdqecwgnprgqvyqwyrttdt 137
gi 115402273 165 RVEIIGGSLASGQFAty--------eALSGWAYLFAEGLg----NAEYTITAYPGVCladmkcygggvhgmpwfwhrasd 232
gi 48865754  133 NLVFIGDSIINGQKIlsds----fdtSAHRPDKSWAYLLse-klDFNNLRIAYGGTGitqraniypptaidfi------- 200
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 121827    678 ------pytlpysgvrwdfskyvPQVVVINLGTNDFstsf-adktKFVTAYKNLISEVRRNYPDahifccVGPMLWGTgl 750
gi 48870801  204 ---------vkyvnfsvkaprinPDLVLINLGTNDArye----ddVFEMYFVWFINEVKKQFPHari-iiITPFNQAHs- 268
gi 40744082  222 pgsrarnmyggepeewdvtaeqpADLVIIQMGGNDHrhpneipgeNFYQGYVDLIENIHQHWPDasivimTQWGIWNQeg 301
gi 115387605 153 vgaranatygnrsvpwdptarraADLVVINLGTNDSrdpnnipggEFYNAYVGLVDEIHRVWPAtqiilmGLWGEFEAtg 232
gi 23024922  183 ---------lwhvapnverprasSDLVIVNYGTNDYnyga--tvqDFCFGLRVYLLELIKRFHD------AKIVLLVPfn 245
gi 70988681  128 -------------pkwnfaaqrpADLVVINIGTNDNnpannvsstDYYNDYITLVGNIHKIWPKadivlmSLWGGFGAsg 194
gi 28272603  202 ---------ltavdskttwqpvpTDLVVINVGTNDRhtd----dtTFTVVLRRFLNQVQTLYPNsrl-avMIPFNQNFas 267
gi 40743290  138 -saramkiygdeppkwdfksqqpADLVVINIGTNDNnpannvpseDYFNDYVKLIADIHGIWPHaqivlmSLWGGFGAsg 216
gi 115402273 233 pgvraqamygkdpekfdvkgdqpADLVIIQMGGNDHrkpneisgdDYFHDYVRLVDDIHHTWPKativlmSQWGEWTLeg 312
gi 48865754  201 -------wnsalnvsrpidysqpLAGVIVNLGTNDRsas----seEFSFSLKALLRELKKRFHE------TKIIVVEPfn 263
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
Feature 1                                                       # #                  
gi 121827    751 ---------dlCRSYVTEVVNDCnrsgdlkVYFVEFPqqdgstgyGEDWHPSIATHQLMAERLTAEIK 809
gi 48870801  269 ----------hVIKNVAKALKIEl------IPTLDWVie-----tNDEVHPNVEGSKAISDHLVAWFT 315
gi 40744082  302 seytqsviyeeEIQRVYEHFKDRkw---rfVYLFHTDgilghndiNPKNHPTDVGHIKIASHLLQWTN 366
gi 115387605 233 ntyvqkplyvsDIQRVYQHFEGHg-----fVHYFDTKgilqhndiAPRDHPTDVGHLKIASHLLQWVK 295
gi 23024922  246 ---------gaFKKVFEQEIKRF-------DCFVLLDttpw-kisPQQVHPNILEHERVAKLLLGGLI 296
gi 70988681  195 dtyvqgplwvdEIKRVYQHYEKQg-----fIHYFDTAgilqhndiAPQWHPTDVGHLKIAAHLMQWVK 257
gi 28272603  268 ----------iIRAVVAEFMQLQl------IETATWQls-----tTDGVHLDLAGSRMAGELTAQALR 314
gi 40743290  217 dtyvqgplfvdEIKRVYEVFQKLgn----fVHYFDTTgilqhndiAPQWHPTDVGHIKVAAHFMQWVK 280
gi 115402273 313 tqyvpstlyydETKRVHDQFKEHa-----yVRYFETRgilqhndiDPKNHPTDVGHVKIASHLLQWTR 375
gi 48865754  264 ---------gcFQDVFHKVFKDEkhi--slIENNHWNfe----isDHGVHLSVTGQQQAAKTLLPLIE 316

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