Conserved Protein Domain Family
plant_peroxidase_like

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cd00314: plant_peroxidase_like 
Click on image for an interactive view with Cn3D
Heme-dependent peroxidases similar to plant peroxidases
Along with animal peroxidases, these enzymes belong to a group of peroxidases containing a heme prosthetic group (ferriprotoporphyrin IX), which catalyzes a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. The plant peroxidase-like superfamily is found in all three kingdoms of life and carries out a variety of biosynthetic and degradative functions. Several sub-families can be identified. Class I includes intracellular peroxidases present in fungi, plants, archaea and bacteria, called catalase-peroxidases, that can exhibit both catalase and broad-spectrum peroxidase activities depending on the steady-state concentration of hydrogen peroxide. Catalase-peroxidases are typically comprised of two homologous domains that probably arose via a single gene duplication event. Class II includes ligninase and other extracellular fungal peroxidases, while class III is comprised of classic extracellular plant peroxidases, like horseradish peroxidase.
Statistics
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PSSM-Id: 173823
View PSSM: cd00314
Aligned: 34 rows
Threshold Bit Score: 45.9926
Threshold Setting Gi: 85701180
Created: 6-Mar-2002
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
heme binding
Conserved site includes 23 residues -Click on image for an interactive view with Cn3D
Feature 1:heme binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                ## ##  #                                                
1FHF_A        16 PIVFGVIFDAsft------dprIGASLMRLHFHDCFVqg-----------------------cDGSVLLnntdtieseqD 66
1C8I_A        27 FDVLDDLQTNfyqgs---kcesPVRKILRIVFHDAIGfspaltaa----------gqfggggaDGSIIAhsn----ielA 89
gi 68565008   27 QRAKTDLLGLiesvkr-gddlpMIAGTVRLAFHDCIGkg----------------------kcDGCIDH----------S 73
gi 85701180   12 EAVKAALVSHgag-------vaVVGRKINLAGGPSYTvel--------------------grfDGLVSRaly----glsK 60
gi 125548313 123 DDFREMVSEN------------DLLLLSKEKFEEGVTpsayafalveqr--ggretislrtfvAGEIKNln-------vA 181
gi 125599164  39 HVIKAIIQDRg-----------IGGSLIRLIFHDCFVrlidnfarknftveelvvlsgahsvgDGHCSSfta-----rlA 102
gi 209585900 333 ESIPDSIERSh-----------FLGGIVRLAAHDFMDfdrtsd---------------nsfgsDGCFES----------D 376
gi 225709532  34 GLINSTLEDGvr---------vLVPSIVRLVFHDCVDg------------------------cDACFNA----------D 70
gi 225711350  29 YRIRAFIASQttsvp--ephlkLIPGLVRLVFHDCSGkn-----------------------cDGCINK----------T 73
gi 270240967 194 SSFEYRLYNFtakgnadptinqAFLAQLRALCPDVGGdvskkg---------------vpldkDSQFKFdvsf---fknV 255
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
1FHF_A        67 ALPNins---------irGLDVVNDIKTAvens----cpdtVSCADI-LAIAAEIASVlg---------------ggPGW 117
1C8I_A        90 FPANggl---------tdTIEALRAVGINh----------gVSFGDL-IQFATAVGMSncp--------------gsPRL 135
gi 68565008   74 KPGNagl---------krVTDRLDALYDAsyk-------gkISRADF-YALASVTALTrstanl--------sdkynGLR 128
gi 85701180   61 LPELgth--------gltLICISWALRVM------------SNVHDFfVHVAAKVESIh-----------------qYIE 103
gi 125548313 182 KPVSc------------sRLQRIASIFSTtesfl--wilkiCSLSTImREFSGMHSVAslpfk----------dlilSAS 237
gi 125599164 103 APPDqi----------tpSYRNLLNYRCSrgggadpavvnnARDEDL-ATVARFMPAFvgklr----------pvsaLDN 161
gi 209585900 377 MIPNaglpsi---wcegcLLTLLYEDKYRh-----------LSRADFwIASANAVIRQtsin-----------naldLKG 431
gi 225709532  71 LIANrgl---------mkPVNALEPLYQNfk--------dsLSRADF-WALASKIAIQlgvyinnrrckekscympkIDV 132
gi 225711350  74 HPFNgrv---------fpVVEALEPLYNYkdisgf-siknvMSRADF-WAFGSIEATKlaiqlnnqrckfkgcktpiMYL 142
gi 270240967 256 RDGNgvlesdqrlfgdseTQRIVKNYAGNgkgll--glrfyFEFPKAmIKMSSIGSASyl---------------ylVPT 318
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                         ###                            #               
1FHF_A       118 PVPLGRRDSltanrt------------lanqnlPAPFFn------------------LTQLKASFA----VQGl---NTL 160
1C8I_A       136 EFLTGRSNSsqpsp---------------psliPGPGNt------------------VTAILDRMG----DAGf---SPD 175
gi 68565008  129 KFKVGRKDCs-----------------------TSPVEsidssdi------prgsdgTSKTLQFFKs---EFGm---KTQ 173
gi 85701180  104 SMRYGSLSPtifdnyskdcmiahgaahflkxrpPDPAEtrggavadngsgavarmptLEEYGTNLTkl-aEEG----KAN 178
gi 125548313 238 EKNSGGNDQnra------------------wnvPEPLMdylktnln---dsqldavnAGLSRRSFVliqgPPGt--gKTQ 294
gi 125599164 162 TYYRNNLDKvams-----------------lisISTASlqynf----------ygssCPNAEQTISn--vVYGlidaDPS 212
gi 209585900 432 VFAWGRVDAescsg--------------ssnrlPAPTG-------------------CAQTEAAFIt---RMGl---EWI 472
gi 225709532 133 RFRFGRKDCasspvh------------sndtfiPSPFSn------------------SSSLFPWFKe---NFNf---KPN 176
gi 225711350 143 PFKFGRKDCp-----------------------TSPYYttditpe-----lppafldNRATLRFFRk---NFGf---NAE 188
gi 270240967 319 ERRDGRLVS------------------------LSPDAlnlla----------ltdsIHVLRQKFA----AKGl---NNH 357
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1            ##   ## #        #####                                                      
1FHF_A       161 DLVTLS--GGHTF--------GRARCstfinrlynfsntgnpdptlntty----------levlrarcpqnatgdnltnl 220
1C8I_A       176 EVVDLL--AAHSL--------ASQEGlnsaifr---------------------------------------------sp 200
gi 68565008  174 EAVALL--GAHTLgrcslqnsGFVGSwvdqrfsta----------------------------------------ppgee 211
gi 85701180  179 FDAAMVklKNFSFilmf-gvlGTIISfclissgavlllkhhvfpdsninpss-------gaaitsgvrgdlrayvvayld 250
gi 125548313 295 TILGLLsaVLHSAparmqtkgGFDVKkhgpeldiegnfrqrlygqlnsdgkpdftlnpayaaelrercpssggdqnlfal 374
gi 125599164 213 MAPALLrlHFHDCfv-----mGFNASilldppkak-----------------------------------------gspe 246
gi 209585900 473 DAVALM--GAHSL--------GRGSIdfsghegv-------------------------------------------wva 499
gi 225709532 177 QVVAIM--GMHTL--------GKAGSp----------------------------------------------------- 193
gi 225711350 189 ETTAIM--GGHSI--------GFTANatripg----------------------------------------------tw 212
gi 270240967 358 DLVTLV--GAHTI--------GQTDCsffqyrlynfmekgnadptin----------------qaflaqlhalcpecgnv 411
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                       # #              
1FHF_A       221 dlstPDQFDN--------RYYSNLLQln---------------------------------gLLQSDQELFSTpg----- 254
1C8I_A       201 ldstPQVFDT--------QFYIETLLkgttqpgpslgf-------------aeelspfpgefRMRSDALLARDs------ 253
gi 68565008  212 nlspTSILDN--------AYYRMIIDivpwtqvningtriqwqepsnsipndklpeskrsplLLNSDMAISWIikpsdal 283
gi 85701180  251 psrtSFTVDN--------AIYGEIRRtvl-------------------------------awLIDSGTLQLSE------- 284
gi 125548313 375 dpasQFRFDN--------QYYRNILAmn---------------------------------gLLSSDEVLLTKs------ 407
gi 125599164 247 ktgiPFRGYNp------lNKFKAAFKafc-------------------------------pgKVPCPEILAFA------- 282
gi 209585900 500 nadeAQIFDK--------RYYEEIYSnswrprvgertqnw--------ttgppnsddpnprlMLNTDICLVYDidesvdc 563
gi 225709532 194 ---fNDTWENgstdgisnFYFRKIADpnhcwvqeyvtpersg----lphkaffwrtdefkgfALPVDMTLFKAiqvnett 266
gi 225711350 213 evgnVDGFSN--------QYFKNIINknlnwnqattltdt--------gekrfrwigngdafGLQTDINLVRDitvnttt 276
gi 270240967 412 strvPLDKDSqik--fdvSFFKNVRVgn---------------------------------gVLESNQRIFGDs------ 450
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|..
Feature 1                                                  #   #     
1FHF_A       255 ----------------aDTIPIVNSFSsn------qNTFFSNFRVSMIKMGN 284
1C8I_A       254 -----------------RTACRWQSMTss------nEVMGQRYRAAMAKMSV 282
gi 68565008  284 gtvscrptslktpcrhsNAHTFAKIYAkn------nALWVKDFTKAFNKMIE 329
gi 85701180  285 -----------------KVLALVLTMV---------AATVLGVAKSMIKMGQ 310
gi 125548313 408 ----------------rETMELVHRYAas------nELFFAQFAKSMVKMGS 437
gi 125599164 283 -----------------ARNSVANSGGlvyp--vppGTRKGNFSSAFSVFSR 315
gi 209585900 564 ct------rtdqffpegGTECLTDELAsrqcpfysqSSSRIEAVDAVEEMLG 609
gi 225709532 267 ges----sctyhdckraSTMGMFKRYAsd------gANWARHIRHLFPRIIE 308
gi 225711350 277 ges-----spyntspksPTYKYVERLTh-------qLYFSYLYSKTFMKMIS 316
gi 270240967 451 -----------------ETQRIVKNYAgnrr--eptESFASLFYLLMVQMEP 483

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