2GAT


Conserved Protein Domain Family
ZnF_GATA

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cd00202: ZnF_GATA 
Click on image for an interactive view with Cn3D
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
Statistics
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Aligned: 43 rows
Threshold Bit Score: 43.9006
Threshold Setting Gi: 19073947
Created: 1-Nov-2000
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
zinc bindingDNA-binding
Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1:zinc binding site [ion binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1       #  #                     #  #                               
2GAT_A       6 VCSNCQT-STTTLWRRSp---MGDPVCNACGLYYKLHQ---VNRPLTMRk--DGIQTRNRK 57   chicken
NP_036234  506 ACRHCFT-TTSKDWHHGg--rENILLCTDCRIHFKKYG---ELPPIEKPvdpPPFMFKPVK 560  human
732160     471 FCFHCGE-TETPEWRKGp--yGTRTLCNACGLFYRKVTk-kFGSKSSNLl--LRYRRSIDL 525  baker's yeast
Q07928      71 RCPQCAViKTSPQWREGp--dGEVTLCNACGLFYRKIFl-vFGKDLAKRy-fNEIKGVSVK 127  baker's yeast
AAB36702   293 SCEFCGS-SQTPTWRRGp--sGKGSLCNACGIKWRLKGkdgIFKPSQKQq-nRQKPIMSAQ 349  Dictyostelium discoideum
1730963    200 ACHHCYG-AESKDWHHA----NGLLLCTDCRLHYKKYG---QLRQIANRp--SQVPACLFK 250  Caenorhabditis elegans
731913      52 TCGQCGEiKTSLQWREGp--nGAACLCNACGLFFRKLIl-rFGRAAAKRy-mEQIKGTGTK 108  baker's yeast
AAD55388   458 PCESCGT-TKSSQWNSVssghSTSRLCLSCWEYWRRYG---SMKSATKGd-aGEGDAKKKS 513  fruit fly
CAC48044   367 VCISCGS-DQSPCWRPSws-iKQGQLCNSCGLRYKKTKa--RCLNDKCKk--IPAKGEWTL 421  Candida albicans
2498590    392 ACESCYT-TQSYQWYSWgppnMQCRLCASCWTYWKKYGg--LKMPTRLDg-eRPGPNRNNM 448  Norway rat

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