2GAT


Conserved Protein Domain Family
ZnF_GATA

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cd00202: ZnF_GATA 
Click on image for an interactive view with Cn3D
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
Statistics
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PSSM-Id: 238123
View PSSM: cd00202
Aligned: 43 rows
Threshold Bit Score: 43.9006
Threshold Setting Gi: 19073947
Created: 1-Nov-2000
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
zinc bindingDNA-binding
Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1:zinc binding site [ion binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
Feature 1         #  #                     #  #                               
2GAT_A         6 VCSNCQT-STTTLWRRSp---MGDPVCNACGLYYKLHQ---VNRPLTMRk--DGIQTRNRK 57
gi 19923393  506 ACRHCFT-TTSKDWHHGg--rENILLCTDCRIHFKKYG---ELPPIEKPvdpPPFMFKPVK 560
gi 732160    471 FCFHCGE-TETPEWRKGp--yGTRTLCNACGLFYRKVTk-kFGSKSSNLl--LRYRRSIDL 525
gi 9910692    71 RCPQCAViKTSPQWREGp--dGEVTLCNACGLFYRKIFl-vFGKDLAKRy-fNEIKGVSVK 127
gi 1685115   293 SCEFCGS-SQTPTWRRGp--sGKGSLCNACGIKWRLKGkdgIFKPSQKQq-nRQKPIMSAQ 349
gi 1730963   200 ACHHCYG-AESKDWHHA----NGLLLCTDCRLHYKKYG---QLRQIANRp--SQVPACLFK 250
gi 731913     52 TCGQCGEiKTSLQWREGp--nGAACLCNACGLFFRKLIl-rFGRAAAKRy-mEQIKGTGTK 108
gi 5901735   458 PCESCGT-TKSSQWNSVssghSTSRLCLSCWEYWRRYG---SMKSATKGd-aGEGDAKKKS 513
gi 15072780  367 VCISCGS-DQSPCWRPSws-iKQGQLCNSCGLRYKKTKa--RCLNDKCKk--IPAKGEWTL 421
gi 2498590   392 ACESCYT-TQSYQWYSWgppnMQCRLCASCWTYWKKYGg--LKMPTRLDg-eRPGPNRNNM 448

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