Conserved Protein Domain Family
RICIN

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cd00161: RICIN 
Click on image for an interactive view with Cn3D
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ligand binding occurs on exposed surfaces of the compact domain sturcture.
Statistics
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PSSM-Id: 238092
View PSSM: cd00161
Aligned: 104 rows
Threshold Bit Score: 33.2479
Threshold Setting Gi: 2145609
Created: 1-Nov-2000
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
Q-X-W motifputative sugar
Conserved site includes 9 residues -Click on image for an interactive view with Cn3D
Feature 1:Q-X-W motif
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                  ###                                   
1XYF_A       313 GQIKGVg---sGRCLDVPnast--tdgTQVQLYDCHsa--tNQQWTYTd---AGELRVy----gDKCLDAAgtg----ng 374
1HWM_B        13 RRIVGRd----GLCVDVRngyd--tdgTPIQLWPCGtq--rNQQWTFYn---DKTIRSm-----GKCMTANgln----sg 72
1HWM_B       142 TLIVGYn----EMCLQANge------nNNVWMEDCDvt-svQQQWALFd---DRTIRVnn--srGLCVTSNgyv----sk 201
gi 18693237  726 TYVRIVnr-asDKCMDIPgngsdmvngTDVILYDCErd-awDQRWSFDa---DKRMFSnka-npSLCLDNRgqay---ne 796
gi 13365855  189 VYIRIKnr-aqDEYLTVTgnla-dtraTSVCISPYSgk--dTQIWHYC----RGLFKSka---sDTCLDVIggrd--tpg 255
gi 12643308 1588 IYFRLRnk-atGLFMSTNgnl---edlKLLRIQVMEdvgadDQIWIYQ----EGCIKCri--aeDCCLTIVgslv--tsg 1655
gi 10336570  419 GDYNIFnldlpNQVVDFSnqp----dlLVHGHEFCDn---eNQTWHFTynstYHAYKIwsgrksNLLLTWDsnat--ske 489
gi 5902922   267 GEFMIEsikdkNSFLDLSkn-----vnGGVIHSNLYsg-gdNQIWVFSyddnKKAYRIqs--yqNSYLYLSwdsnasske 338
gi 5902922   570 GDYNIFndnfpNIAIDFTnq-----egSLIHGHNFCsn--nNQKWSFVfdgkRKAYRIksgvrsNLWLSWDsnas--ske 640
gi 282374    730 GYFNISskknfNKIITMNsn-----ktQAVIFDNIGi---nNQSWKLKyndnKNAYQIhil-dnFLYFQGGhn------- 793
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
Feature 1                       ###                                                   ###  
1XYF_A       375 tKVQIYSCWg--GDNQKWRLNsd-----gSIVGVq-sGLCLDAVgggt-angtLIQLYSCsng----snQRWTR 435
1HWM_B        73 sYIMITDCStaaEDATKWEVLid-----gSIINPs-sGLVMTAPsgas--rttLLLENNIha-----asQGWTV 133
1HWM_B       202 dLIVIRKCQg--LATQRWFFNsd-----gSVVNLk-sTRVMDVKesdv--slqEVIIFPAtgn----pnQQWRT 261
gi 18693237  797 gEIVVWECVd--SDNLRWDYDg------rFIRSAhdaNIVADAYgrg---ndaQVGQWQFhgg----anQQWLL 855
gi 13365855  256 aKVALWTEHg--QFRQKWRLNqn-----gTISSYlsdQLVLDVKggny-cdktHVIVNQPleg---eetQKWDI 318
gi 12643308 1656 sKLGLALDQn--ADSQFWSLKsd-----gRIYSKlkpNLVLDIKggtq-ydqnHIILNTVske---kftQVWEA 1718
gi 10336570  490 mVVRAYTESr--SKNQYWRIEqtgs-ksyKLRNLensNMILGLTnvstsygglNLMVQDDsngn-snlhSDWDI 559
gi 5902922   339 mILRGYTNSg--SNNQYWQIEqtg--knyRLRNLlnlDMIITAQdkpsafggkEVIVNTEisnsntkisQEWKM 408
gi 5902922   641 mVLRAYTESg--SSNQYWRLDeand-gsyRIRNLqdyYKLIALTnkntpyggkELIVSDNke-----sgNTWYL 706
gi 282374    794 iVATMRNVTn-dDLRSYWYVEynfnkdgfIIRNAfdtSYVLDVFqgnf-anntPIITYQNyln----dnQLWNF 861

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