Conserved Protein Domain Family
GGL

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cd00068: GGL 
Click on image for an interactive view with Cn3D
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors
Statistics
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PSSM-Id: 238024
View PSSM: cd00068
Aligned: 27 rows
Threshold Bit Score: 52.2914
Threshold Setting Gi: 14571686
Created: 1-Nov-2000
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
beta subunit
Conserved site includes 15 residues -Click on image for an interactive view with Cn3D
Feature 1:beta subunit binding site [polypeptide binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
Feature 1       #  #   #  #   #      # #  ##  ##  #        ##                #    
1GP2_G        9 IAQARKLVEQLKMEANID--RIKVSKAAADLMAYCEAHakEDPLLTPVPa-------SENPFREKK 65
gi 14423722  11 RDALKKQIENMKYQASME--RWPLSKSIAEMRSFIEENekNDPLINAPDk-------KNNPWAEKG 67
gi 585180     8 LQQQRVVVEQLRREAAID--RQTISESCAKMMKYITEHeqEDYLLTGFTs------qKVNPFREKS 65
gi 5748550   28 VPQMKKEVESLKYQLAFQ--REMASKTIPELLKWIEDGipKDPFLNPDLm-------KNNPWVEKG 84
gi 7498606    3 KSDMQRTVDSLRSQLNIE--RTPITVSAAELRRFTESQ--EDPLVNPIDk-------KVNPWAEKS 57
gi 1706621  334 QDTLKLEIVQLNSRLSKN--VLRTSKVVENYLAYYEQRrvFDPLLTPPGsqadpfqsQPNPWINDT 397
gi 7496101  204 AQGYRCLMDRLRFAIKTKp-WLKALKASDTMVTWVDQRaeFDPFLHPPQ--------PSNPWISDE 260
gi 8489000  219 VTAVRKEIMYYQQALMRS--TVKSSVSLGGIVKYSEQFssNDAIMSGCL--------PSNPWITDD 274
gi 7293293  429 VEQLTRIIALRKQKLERR--TIKVSKAAEALVAYYDQYneFDYFITSPE--------LPNPWQTDS 484
gi 14571686   6 LKKVLKENETLKAQLEKSttILKVSEACESLQDYCTKT--SDPFIPGWS--------GENEWTKPL 61

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