Conserved Protein Domain Family
ENDO3c

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cd00056: ENDO3c 
Click on image for an interactive view with Cn3D
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
Statistics
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PSSM-Id: 238013
View PSSM: cd00056
Aligned: 140 rows
Threshold Bit Score: 64.9554
Threshold Setting Gi: 13475376
Created: 1-Nov-2000
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
Conserved site include 1 residue -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                       
1MUY_A       31 YKVWLSEVMLQQTQVATVIPYFERFMARf---------------pTVTDLANAPl-DEVLHLWtglg---yyaRARNLHK 91
1EBM_A      130 IECLFSFICSSNNNIARITGMVERLCQAfgprliqlddvtyhgfpSLQALAGPEveAHLRKLGlg-------yRARYVSA 202
gi 232205    36 YVILITEILLRRTTAGHVKKIYDKFFVKy---------------kCFEDILKTPk-SEIAKDIkeig--lsnqRAEQLKE 97
gi 14601039 100 WAILVAAFLLRKTTARQVVRVYEEFLRRy---------------pNPKALASARe-DEVRELIrplg--iehqRAKHLIE 161
gi 7141252   40 WAVLVAALLLRKTTVKQVVDIYREFLRRy---------------pSPARLADASv-EEIKAIIqplg--mehvRATLLKK 101
gi 15897791  30 EEVWFRELTLCLLTANSSFISAYQALNCl----------------GQKIYYANE--EEIRNILksckyrfynlKAKYIIM 91
gi 10639161  55 KEVLFKELVFCILAANTSASMSLRMQESi----------------GDGFLYLSR--DDLRKALkenkyrfynvRSDFIVK 116
gi 13540893  34 KDALFEELCFCILAANTSARMALDMQNRig--------------kGFLYLSENElrEKLKAFKyrf----ynvRPRYIVE 95
gi 15921483  30 ENVWFRELILCILTSNSSFISAYKALNYim--------------dEIFSLSEDQmsKRLRLAGyrf----ynlKAKYIAN 91
gi 2833558   34 NEEWFKELCFCILTANFTAEGGIRIQKEig--------------dGFLTLPREEleEKLKNLGhrf----yrkRAEYIVL 95
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                 #                     
1MUY_A       92 AAQQVATLhggkf----------petfEEVAALPGVGRSTAGAILSLSLg-kHFPIL-DGNVKRVLarcyavsg-----w 154
1EBM_A      203 SARAILEEqgglawlqqlressyeeahKALCILPGVGTQVADCICLMALdkpQAVPV-DVHMWHIAqrdyswhpttsqak 281
gi 232205    98 LARVVINDyggrv----------prnrKAILDLPGVGKYTCAAVMCLAFg-kKAAMV-DANFVRVInryfggs------y 159
gi 14601039 162 LAKHIEARyggri----------pcskEKLKELPGVGDYIASEVLLAACg--SPEPLlDRNMIRILervlgvks-----a 224
gi 7141252  102 LSEELVRRfngqi----------pcdrDALKSLPGVGDYAASEVLLTACg-kPEPLL-DRNMIRVIervfgiks-----k 164
gi 15897791  92 AREKVYGRlkeeikpla--dedqqlarERLLNIKGIGMKEASHFLRNVGy-fDLAII-DRHIIDFMrrigaige-----t 162
gi 10639161 117 SRNIIDDLpalvasp-----dhegsrdYLVENVYGIGYKEASHFLRNVGi-fDFAIL-DKHIMKWMaqyypv-------- 181
gi 13540893  96 SRDIVDELpyivsmd-----nkeeardLLVENVYGFGYKEASHFLRNVGv-fDFAIL-DKHILEWLsryfqv-------- 160
gi 15921483  92 ARKLYGNLktkikpiad--ysqeearqYIINNIDGLGLKESSHFLRNVGy-fDLAII-DRHVLHFLneigts-------- 159
gi 2833558   96 ARRFKNIKdivesfe-----nekvareFLVRNIKGIGYKEASHFLRNVGy-dDVAII-DRHILRELyennyid------e 162
                       170       180       190
                ....*....|....*....|....*....|....*.
Feature 1                                           
1MUY_A      155 pgkkevENKLWSLSEqvtp--avgVERFNQAMMDLG 188
1EBM_A      282 gpspqtNKELGNFFRslw---gpyAGWAQAVLFSAD 314
gi 232205   160 enlnynHKALWELAEtlvp--ggkCRDFNLGLMDFS 193
gi 14601039 225 kkrphtDPKMWSTARrivpkdpdmAKEFNYGMLDLA 260
gi 7141252  165 krrphtDRELWNFARslvprdpelAKEFNFGVLDFA 200
gi 15897791 163 nvkqlsKSLYISFENilks--iasNLNMSVGILDLF 196
gi 10639161 182 -kkntsRKNYLYNEEifrn--isaGFGIEPGILDLF 214
gi 13540893 161 -kkntsRKNYLYNESifre--iakSVGMEPGVLDLY 193
gi 15921483 160 nlkiknKKDYYLAESilks--isiNLGIQVGLLDLY 193
gi 2833558  163 ipktlsRRKYLEIENilrd--igeEVNLKLSELDLY 196

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