2I71,4EOG


Conserved Protein Domain Family
cas_MJ1666
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TIGR01897: cas_MJ1666 
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CRISPR-associated protein, MJ1666 family
CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model describes a Cas protein about 400 residues in length, found mostly in the Archaea but also in Aquifex.
Links
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Statistics
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PSSM-Id: 273862
Aligned: 11 rows
Threshold Bit Score: 294.317
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2I71_A        23 ASIVFSTIGNPKGYQKVTYEIDG----------EKFESNVSVLALRDLLKVDK---TVVILGISVADVYNCKY------- 82  Sulfolobus solf...
WP_010884277   1 MRVLISPWGDFRKWKVAKYTFSG----------KSLESRSTLPIMVDVIRPQE---TIIIVPDTLSSDFSSQE------- 60  Pyrococcus hori...
WP_011007044   2 KFLVVAPWGNPSMWRRARYRIELrhkaleglgeGEVETCSSTKALAELLRRRG---DVKVLIFGLDTVAQPAG------- 71  Pyrobaculum aer...
WP_010880198   2 KKVVIAPWGDPTNWQRVKYSYND----------HEDKYPSATGIIIKAEKPDS---VILVCPDSLAEKRIPYK------- 61  Aquifex aeolicus
WP_011012267   3 MRVLVTTWGNPFQWEPITYEYRG----------IKVKSRNTLPILVKTLEPER---ILILVADTMANYYDSGKnkpeiee 69  Pyrococcus furi...
WP_010871190   2 QKILIAPWGNFSSWKKVIYSFNG----------VEKESKSSLSAIYDKINPDK---VYILVLDTLSNLESENY------- 61  Methanocaldococ...
WP_009991619   2 ASIVFSTIGNPKGYQKVTYEIDG----------EKFESNVSVLALRDLLKVDK---TVVILGISVADVYNCKY------- 61  Sulfolobus solf...
WP_011026631   2 KVIYQIGRFDKGFMKTQEFTFRQek-------yTEVLTSFVMKKFFQKKNPQEksmVVLIFPVSLILNESAIK------- 67  Caldanaerobacte...
WP_010916370   2 KSIFISLWGNPERWNVTRYSFNS----------KTCESITSSRVIYENFKTDY---CIIYIPNSIYPGIYKDD------- 61  Thermoplasma vo...
BAB59418       4 MKILFAPIGDPKNYDEVKYRIDG----------KDYPSNASFKVIKEALNMDE---TIVYAGLSLCTNSNYND------- 63  Thermoplasma vo...
4EOG_A         3 xRVLVTTWGNPFQWEPITYEYRG----------IKVKSRNTLPILVKTLEPER---ILILVADTXANYYDSGKnkpeiee 69  Pyrococcus furi...

2I71_A        83 --------------Ad------------------------yRSCKE----------CIIQNs-K--------NDLGISES 105 Sulfolobus solf...
WP_010884277  61 --------------Sm------------------------wNSVKD----------EVKEF--T--------NQLGVEDV 82  Pyrococcus hori...
WP_011007044  72 --------------Grt----------------------prEIAEE----------KYREWa-R---------ALGVEG- 94  Pyrobaculum aer...
WP_010880198  62 --------------EikiqcsgnlsdktqgnlpfenyeeikSKVEN----------KIKDFfsK--------NINFHKKP 109 Aquifex aeolicus
WP_011012267  70 ksfssysevvedtkEri----------------------lwHIKEEvieelreedpELAKKi-E--------NMLKDERI 118 Pyrococcus furi...
WP_010871190  62 --------------Gdi----------------------vkE-VKE----------KTENFi-K--------ENLNIDNY 85  Methanocaldococ...
WP_009991619  62 --------------Ad------------------------yRSCKE----------CIIQNs-K--------NDLGISES 84  Sulfolobus solf...
WP_011026631  68 --------------Eviesndeaie------kfkeklerfkDMVPN----------TLQEYs-TdpyafysfHPHCKIAD 116 Caldanaerobacte...
WP_010916370  62 --------------Tyls--------------------qyqDLINS----------KLCEFl-Nskd---teSAEFYKNS 93  Thermoplasma vo...
BAB59418      64 --------------Y--------------------------VSCSN----------YISNLv-K--------DKLQLNDE 84  Thermoplasma vo...
4EOG_A        70 ksfssysevvedtkEri----------------------lwHIKEEvieelreedpELAKKi-E--------NXLKDERI 118 Pyrococcus furi...

2I71_A       106 YVVAPNVYQKF----K-----------GKPDHY----FTY----IYYHSLRILEK-Eg-I--NEVFIDTTHGINYXGVLA 158 Sulfolobus solf...
WP_010884277  83 KIIVVPGSGSF----Sngs------ffGNPMDA----YMF----LLYELAKELPL-E--I--KEVHLDVTHGLNYLTFFT 139 Pyrococcus hori...
WP_011007044  95 EVVSLPGIGLF----Hgwr------yeGKPLHL----FNA----AFYHILKTAEE-Lk-P--SFIVVDLTHGVNYQTIAV 152 Pyrobaculum aer...
WP_010880198 110 DVIISYSFGSY----Ntle------feGQAEDF----FAGvlkgLVYKFTEYLEK-Gi-PekIEIILDVSHGINYTTVMT 173 Aquifex aeolicus
WP_011012267 119 TIEVLPGVGVF----Gnit------veGEMLDF----YYY----ATYKLAEWLPV-Qn-N--LEVYLDLTHGINFMPTFT 176 Pyrococcus furi...
WP_010871190  86 EVIVCPGVGTF----YnkdfekyfkfyGNLTDY----YSF----ALYELSKRLDG-D-----LEVHLDLTHGLNYMPVLT 147 Methanocaldococ...
WP_009991619  85 YVVAPNVYQKF----K-----------GKPDHY----FTY----IYYHSLRILEK-Eg-I--NEVFIDTTHGINYMGVLA 137 Sulfolobus solf...
WP_011026631 117 DFFVIHSLGGY----Kifgey--iefnSDYNDIvlqiFSD----MAIRYLNEYNR-DneT--MEFYIDISSGHNIYISAL 183 Caldanaerobacte...
WP_010916370  94 NKIIFPSKGSFtadnKnyi------fdFDINYI----YSY----FYRSILNYLESvDk-I--NKIIVDITHGINFLEFIF 156 Thermoplasma vo...
BAB59418      85 SVIVAPNIYGD----Kftq------pdGKNTLY----FDF----IYYNTLKILEN-Ek-P--DEIYIDITHGINYMPLLA 142 Thermoplasma vo...
4EOG_A       119 TIEVLPGVGVF----Gnit------veGEXLDF----YYY----ATYKLAEWLPV-Qn-N--LEVYLDLTHGINFXPTFT 176 Pyrococcus furi...

2I71_A       159 KEAIQlA------VSAYAAKsEKEVKVSLYNSDPVGKD------VSDTVKLH-------EIEAIKISPLSGLKYVTYQIL 219 Sulfolobus solf...
WP_010884277 140 VRVVQ-E------LLGILSI-RKGVVLKTYSSDPFVDG------SVRHLRVN-------LIEEATIDPKPLSEFLEGKFL 198 Pyrococcus hori...
WP_011007044 153 LYAAV-A------ASVLL---EKEDRLLLYNSEPYPAEysaetcIKEAQRVErre-gvpQLTALDVRQLQDAVGAIRLLW 221 Pyrobaculum aer...
WP_010880198 174 YEAVR-T------LAQLLAY-FTEVSLKVLNADPVIGRn-----IQKPLRINeieyyssIFPNLVVYRIKKEDKECEQIL 240 Aquifex aeolicus
WP_011012267 177 YRALR-N------LLGLLAY-LYNVKFEIVNSEPYPLG------VSQEIREDtil-hirEIGEGVVRPRPQYSPVEGKLY 241 Pyrococcus furi...
WP_010871190 148 YRVIK-D------LLEILAI-KNKVRLVVYNSDPYVGR------EKEILNIHtve-dviIKPSYDIKGMTLDFLDATKFV 212 Methanocaldococ...
WP_009991619 138 KEAIQlA------VSAYAAKsEKEVKVSLYNSDPVGKD------VSDTVKLH-------EIEAIKISPLSGLKYVTYQIL 198 Sulfolobus solf...
WP_011026631 184 LEAAR-YfsvfsgLLNWLKK-EKRPKIFLAFSDPILPGt----tGMKEYEIHieelrfkTFFSSPIGEEELDNFNLARRI 257 Caldanaerobacte...
WP_010916370 157 LESLMyA------LRVYALSnKIDVNIEYYNSDPYSN--------FAILNIY-------KIKSIEIEYKNVLSIISRDFI 215 Thermoplasma vo...
BAB59418     143 TDAIRlA------TYTYLLG-RNSIDLAIFNSEPVIKG------YSGPYNIAn------VYSERLYVRQALLSVLMPFLS 203 Thermoplasma vo...
4EOG_A       177 YRALR-N------LLGLLAY-LYNVKFEIVNSEPYPLG------VSQEIREDtil-hirEIGEGVVRPRPQYSPVEGKLY 241 Pyrococcus furi...

2I71_A       220 NKDK---------N--------------------FFNKIFS-DSVNAIP--R-FATALDNGLFIYLSEK----------- 255 Sulfolobus solf...
WP_010884277 199 VNYS---------MdrvefgeiarrlkakeldlgRINSWIA-SLKHGLPl-V-FTTMYPQEGEVEGVLE----------- 255 Pyrococcus hori...
WP_011007044 222 ALRR---------Laplkidveiq-spelrrrfdKVITSYRlLASGAAAl-L-FPKAKFSGRAPEFYVPgegpgavpepr 289 Pyrobaculum aer...
WP_010880198 241 EAYD---------Dsineig--------dnmkleREHIFLS-AIIHGTPl-Y-ILTYMPSSKDLKAKID----------- 289 Aquifex aeolicus
WP_011012267 242 W-----------------------------------NAFIS-SVANGFPl-V-FASFYPNIRDVEDYLN----------- 272 Pyrococcus furi...
WP_010871190 213 DKKEigkikkeinMnpkike--------lrimkqNINAFIA-SIVYALPl-V-YSTFFVKKDKIEIYLN----------- 270 Methanocaldococ...
WP_009991619 199 NKDK---------N--------------------FFNKIFS-DSVNAIP--R-FATALDNGLFIYLSEK----------- 234 Sulfolobus solf...
WP_011026631 258 AGKE---------Kelknvl---------qklfeNFLICFS-AIKNNTPl-VlYHFNFDAWEDVISFLK----------- 306 Caldanaerobacte...
WP_010916370 216 NMYR---------Hnkkdik---------dyfklNFNEDLS-DYIKACS--I-MAQSVTVPYLMYLIIN----------- 262 Thermoplasma vo...
BAB59418     204 NENK---------Nnitn------------kvlkGINNCNS-DLIYSNAnaL-FSGIFPFVLLSRREIE----------- 249 Thermoplasma vo...
4EOG_A       242 W-----------------------------------NAFIS-SVANGFPl-V-FASFYPNIRDVEDYLN----------- 272 Pyrococcus furi...

2I71_A       256 -DSSLHLKRLEDDLSKdp---lLTPSENEINVVYKDXKYALSHALFYVISRFSGN--------------VDLDTLRHYAE 317 Sulfolobus solf...
WP_010884277 256 -DVVAKFLEGFNVGEG------KVVRSISLGKDFGSLAKLYFQLRVLKDLKEMYNlpk---------deASVEELLKISE 319 Pyrococcus hori...
WP_011007044 290 iDIKVDPDRRVVSYGEademysVAVALHYLERALDELRAEDLVSFLNRVAKHYKEigvtltsivvdttaKQLGRMVKAAE 369 Pyrobaculum aer...
WP_010880198 290 -NAAGYYEKNIIIENEigekkiKVKRKLRFTENYITMLKAYFLSFILE---KKGFskk---------eeVLLEDINKLNE 356 Aquifex aeolicus
WP_011012267 273 -KKLEEFLVGIEVGERedg-kpYVKREKALDRSFKNASKLYYALRVFN--TKFQNypk---------keVPIEEIMEISK 339 Pyrococcus furi...
WP_010871190 271 -ELIGAFISNIKINPEdk----ilKRYLYFGEGFNSLVKAYFASKISE----IPQlik---------deLSLEEIDELKN 332 Methanocaldococ...
WP_009991619 235 -DSSLHLKRLEDDLSKdp---lLTPSENEINVVYKDMKYALSHALFYVISRFSGN--------------VDLDTLRHYAE 296 Sulfolobus solf...
WP_011026631 307 -D-FLEMLKRKLSGTWe------sSPVLFKSDYLNTILSLGFYAGILEVLETKGIskyd------yengIALEEIKQLFA 372 Caldanaerobacte...
WP_010916370 263 ------IYKKIYEIGSgglevhLNIEDNKIRQTFDNKINVNIETLAFLDTLIKINssik------ydngFKIPDIYTFTD 330 Thermoplasma vo...
BAB59418     250 -QCIKSVERKIKILDYnnfgieFNTSHKPVYKDTMPIELSYLHSLLYIIEKIIGNmpd--------sscVKISDIKDLAK 320 Thermoplasma vo...
4EOG_A       273 -KKLEEFLVGIEVGERedg-kpYVKREKALDRSFKNASKLYYALRVFN--TKFQNypk---------keVPIEEIXEISK 339 Pyrococcus furi...

2I71_A       318 TYAD-------------------------K--------VTRAIIENEVDKIEKYQXGSERKLLG------------E--- 349 Sulfolobus solf...
WP_010884277 320 EIFT-------------------------G--------RIKHSTKVELDNVANRVEKTEGWVKLs-----------E--- 352 Pyrococcus hori...
WP_011007044 370 ALAD-------------------------Kgvlk-ridGVIELSQLEAMVLFERSNRALELAASwrq------aldE--- 414 Pyrobaculum aer...
WP_010880198 357 MIFR-------------------------Ef------pVLKHRISKETNNINERRDNIPEDFLIy----------rE--- 392 Aquifex aeolicus
WP_011012267 340 IFESlprigiilerqvewlrnlvygrlwyEng----eqKIKKGLLEIIKDKKDKRKEAEALKKGktislaeaakltR--- 412 Pyrococcus furi...
WP_010871190 333 TLFK-------------------------Enp----nsQYIKNEISSLYNIINTKYKEEELSEIlgn-------wtP--- 373 Methanocaldococ...
WP_009991619 297 TYAD-------------------------K--------VTRAIIENEVDKIEKYQMGSERKLLG------------E--- 328 Sulfolobus solf...
WP_011026631 373 SEEN-------------------------SiyklfgleTHIPILGREVHNLCHGGKKKEKSILNqa---------tEews 418 Caldanaerobacte...
WP_010916370 331 NFFS-------------------------Re-------SYNIFIKNELRKIKSKK---------------------E--- 354 Thermoplasma vo...
BAB59418     321 RFST-------------------------Set----isKLVESEIDSIEKLQNISDKPQLLAVIkh---------sQ--- 359 Thermoplasma vo...
4EOG_A       340 IFESlprigiilerqvewlrnlvygrlwyEng----eqKIKKGLLEIIKDKKDKRKEAEALKKGktislaeaakltR--- 412 Pyrococcus furi...

2I71_A       350 -YXKVEGKG----FD-------K---RILYAHGGLPYAGTYV------------------------YK------E-KDKV 383 Sulfolobus solf...
WP_010884277 353 -FFKNANPQ----VD-------P---RNFFAHAGLEANLVEV------------------------KRngelylR-YTKG 392 Pyrococcus hori...
WP_011007044 415 -FAKVLSGE----MErkisdrtL---RNLLAHGGYSHVAVEK------------------------VV------I-KDKK 455 Pyrobaculum aer...
WP_010880198 393 -INRRGNRD----FE-------E---RNFFAHAGFEYNSVML------------------------KKd-----D-KDII 427 Aquifex aeolicus
WP_011012267 413 -IFSPSGER----IEtiespnvV---RNFIAHSGFEYNIVYV------------------------KY------DrLSDR 454 Pyrococcus furi...
WP_010871190 374 -IYKIRREN----ID-------KfkiRNFLAHAGFEKSVTEIyisvenkngkielsektslrynknYI------E-EKNG 434 Methanocaldococ...
WP_009991619 329 -YMKVEGKG----FD-------K---RILYAHGGLPYAGTYV------------------------YK------E-KDKV 362 Sulfolobus solf...
WP_011026631 419 kVYNFIDEGksssFE-------N---RNFLAHSGFERNVTEV------------------------RK------E-EGKL 457 Caldanaerobacte...
WP_010916370 355 -HYDFDIGN----FS-----------RNFKAYAGLLDGLYVL------------------------K-------D-NSID 386 Thermoplasma vo...
BAB59418     360 -SSPKSICQ----AD-------K---RNLLAHGGFEQNVVYL------------------------WR------E-NGEI 393 Thermoplasma vo...
4EOG_A       413 -IFSPSGER----IEtiespnvV---RNFIAHSGFEYNIVYV------------------------KY------DrLSDR 454 Pyrococcus furi...

2I71_A       384 YVTYGDKIDEIE 395 Sulfolobus solfataricus P2
WP_010884277 393 KVRWGGKEEKAE 404 Pyrococcus horikoshii
WP_011007044 456 IVEVVYNGEIVS 467 Pyrobaculum aerophilum
WP_010880198 428 LKVNEQNKEKIE 439 Aquifex aeolicus
WP_011012267 455 LYFFYKDKEKAA 466 Pyrococcus furiosus
WP_010871190 435 IKRFIFKYKDKN 446 Methanocaldococcus jannaschii
WP_009991619 363 YVTYGDKIDEIE 374 Sulfolobus solfataricus
WP_011026631 458 YLRYDKSFEKKI 469 Caldanaerobacter subterraneus
WP_010916370 387 FKTFHFQNQKID 398 Thermoplasma volcanium
BAB59418     394 CVNYCDCIENVR 405 Thermoplasma volcanium GSS1
4EOG_A       455 LYFFYKDKEKAA 466 Pyrococcus furiosus DSM 3638
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