3N2B,2P3E,1TWI,2QGH,1HKV,1KNW


Conserved Protein Domain Family
lysA

?
TIGR01048: lysA 
Click on image for an interactive view with Cn3D
diaminopimelate decarboxylase
This family consists of diaminopimelate decarboxylase, an enzyme which catalyzes the conversion of diaminopimelic acid into lysine during the last step of lysine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Statistics
?
PSSM-Id: 273415
View PSSM: TIGR01048
Aligned: 21 rows
Threshold Bit Score: 516.843
Threshold Setting Gi: 13124089
Created: 8-Oct-2014
Updated: 23-Jan-2015
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3N2B_A        28 FNYQEDGQLWAEQVPLADLANQYGTPLYVYSRATLERHWHAFDKSVgdy------phLICYAVKANSNLGVLNTLARLGS 101 Vibrio cholerae...
P00861         2 PHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALKQFD-----------VVRFAQKACSNIHILRLMREQGV 70  Escherichia col...
Q58497        10 TVEIKDGRFFIDGYDAIELAEKFGTPLYVMSEEQIKINYNRYIEAFkrweeetgkefIVAYAYKANANLAITRLLAKLGC 89  Methanocaldococ...
O27390         5 IEVNDKGHLLIGGADAVELADEYGTPLYVIDEMRIRENYRRLYRAFsgey----srfQVFYACKANTNLAVMRILEEEGS 80  Methanothermoba...
Q9X1K5         1 ------------MDILRKVAEIHGTPTYVYFEETLRKRSRLVKEVFegv------nlLPTFAVKANNNPVLLKILREEGF 62  Thermotoga mari...
P31848        16 TTRDEVGVVCIAGIPLTQLAQEYGTPLFVIDEDDFRSRCRETAAAFgs-------gaNVHYAAKAFLCSEVARWISEEGL 88  Mycobacterium t...
WP_015251780   9 SRQNQHGHLEIGGVDALYLAEKYGTPLYVYDVALIRERAKSFKQAFisag----lkaQVAYASKAFSSVAMIQLAEEEGL 84  Bacillus subtilis
Q55484        33 AVINKNGELEIGGCSVPALVEQFGSPLYILDETTLRQAAQQYRQSFqahy---pgssQVIYASKAWSCLAVVAIAAQEGL 109 Synechocystis s...
1TWI_A         6 TVEIKDGRFFIDGYDAIELAEKFGTPLYVMSEEQIKINYNRYIEAFkrweeetgkefIVAYAYKANANLAITRLLAKLGC 85  Methanocaldococ...
1HKV_A        16 TTRDEVGVVCIAGIPLTQLAQEYGTPLFVIDEDDFRSRCRETAAAFgs-------gaNVHYAAKAFLCSEVARWISEEGL 88  Mycobacterium t...
3N2B_A       102 GFDIVSVGELERVLAAGGD--------PSKVVFSGVGKTEAEMKRALQLKIkcFNVESEPELQRLNKVAGELgvkaPISL 173 Vibrio cholerae...
P00861        71 KVDSVSLGEIERALAAGYNpq----thPDDIVFTADVIDQATLERVSELQIp-VNAGSVDMLDQLGQVSPGH----RVWL 141 Escherichia col...
Q58497        90 GADVVSGGELYIAKLSNVP--------SKKIVFNGNCKTKEEIIMGIEANIraFNVDSISELILINETAKELgetaNVAF 161 Methanocaldococ...
O27390        81 GIDAVSPGEIYTALMAGFD--------PDRILYTGNNVRDDELQFALDSGVr-INVDSRSQLLRLSEIAPEGl---RISF 148 Methanothermoba...
Q9X1K5        63 GMDVVTKGELLAAKLAGVP--------SHTVVWNGNGKSRDQMEHFLREDVriVNVDSFEEMEIWRELNPEGv---EYFI 131 Thermotoga mari...
P31848        89 CLDVCTGGELAVALHASFP--------PERITLHGNNKSVSELTAAVKAGVghIVVDSMTEIERLDAIAGEAgivqDVLV 160 Mycobacterium t...
WP_015251780  85 SLDVVSGGELYTAVAAGFP--------AERIHFHGNNKSREELRMALEHRIgcIVVDNFYEIALLEDLCKETghsiDVLL 156 Bacillus subtilis
Q55484       110 GFDVVSGGELFTTVSALKQlgwdeaeiAEKIYFHGNNKSVQELQEAIAINCt-IIVDNWLELETLTKLAADSgapvKIML 188 Synechocystis s...
1TWI_A        86 GADVVSGGELYIAKLSNVP--------SKKIVFNGNCKTKEEIIMGIEANIraFNVDSISELILINETAKELgetaNVAF 157 Methanocaldococ...
1HKV_A        89 CLDVCTGGELAVALHASFP--------PERITLHGNNKSVSELTAAVKAGVghIVVDSMTEIERLDAIAGEAgivqDVLV 160 Mycobacterium t...
3N2B_A       174 RINPDVDAKTHPYISTGLRDNKFGITFDr--AAQVYRLAHSLPNLDVHGIDCHIGSQLTALAPFIDATDRLLALIDSlk- 250 Vibrio cholerae...
P00861       142 RVNPGFGHGHSQKTNTGGENSKHGIWYT---DLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVIEF--- 215 Escherichia col...
Q58497       162 RINPNVNPKTHPKISTGLKKNKFGLDVEsgiAMKAIKMALEMEYVNVVGVHCHIGSQLTDISPFIEETRKVMDFVVElk- 240 Methanocaldococ...
O27390       149 RVNPLVGAGHHEHCITGGEMSKFGVMERe--APEVYRMAMDLG-FEPVGIHAHIGSGILDPEPFMLAVETLMDIAGRvhe 225 Methanothermoba...
Q9X1K5       132 RVNPEVDAKTHPHISTGLKKHKFGIPLE-----DLDSFMERFRSMNIRGLHVHIGSQITRVEPFVEAFSKVVRASER--- 203 Thermotoga mari...
P31848       161 RLTVGVEAHTHEFISTAHEDQKFGLSVAsgaAMAAVRRVFATDHLRLVGLHSHIGSQIFDVDGFELAAHRVIGLLRDvvg 240 Mycobacterium t...
WP_015251780 157 RITPGVEAHTHDYITTGQEDSKFGFDLHngqTERAIEQVLQSEHIQLLGVHCHIGSQIFDTAGFVLAAEKIFKKLDEwrd 236 Bacillus subtilis
Q55484       189 RLTPGIECHTHEYIKTGHLDSKFGFDPNq--LEAVFTYIAQQPSLHCLGLHAHIGSQIFERQPHKDLGEVLVQWFTKgl- 265 Synechocystis s...
1TWI_A       158 RINPNVNPKTHPKISTGLKKNKFGLDVEsgiAMKAIKMALEMEYVNVVGVHCHIGSQLTDISPFIEETRKVMDFVVElk- 236 Methanocaldococ...
1HKV_A       161 RLTVGVEAHTHEFISTAHEDQKFGLSVAsgaAMAAVRRVFATDHLRLVGLHSHIGSQIFDVDGFELAAHRVIGLLRDvvg 240 Mycobacterium t...
3N2B_A       251 ----aeGIHIRHLDVGGGLGVVYRDEL-PPQPSEYAKALLDRLERH------R-DLELIFEPGRAIAANAGVLVTKVEFL 318 Vibrio cholerae...
P00861       216 ------GQDLQAISAGGGLSVPYQQGEeAVDTEHYYGLWNAAREQIarh-lgH-PVKLEIEPGRFLVAQSGVLITQVRSV 287 Escherichia col...
Q58497       241 ----eeGIEIEDVNLGGGLGIPYYKDKqIPTQKDLADAIINTMLKYkd--kvE-MPNLILEPGRSLVATAGYLLGKVHHI 313 Methanocaldococ...
O27390       226 ----atGVEFEFIDFGGGLGIPYTPEEePLDIDEFASKITGLFKDKlse-ygLgRPMMCLEPGRYIVGDASYLLTRVNTI 300 Methanothermoba...
Q9X1K5       204 -------YGFEEINIGGGWGINYSGEE--LDLSSYREKVVPDLKR---------FKRVIVEIGRYIVAPSGYLLLRVVLV 265 Thermotoga mari...
P31848       241 efgpekTAQIATVDLGGGLGISYLPSDdPPPIAELAAKLGTIVSDEsta-vgLpTPKLVVEPGRAIAGPGTITLYEVGTV 319 Mycobacterium t...
WP_015251780 237 ----sySFVSKVLNLGGGFGIRYTEDDePLHATEYVEKIIEAVKENasr-ygFdIPEIWIEPGRSLVGDAGTTLYTVGSQ 311 Bacillus subtilis
Q55484       266 ----tyGLPLTELNIGGGLGICYTESDdPPSIEEWAQVAAISVAKAcdr-qnIpYPKLIAEPGRSLVGSACVTAYRVGGR 340 Synechocystis s...
1TWI_A       237 ----eeGIEIEDVNLGGGLGIPYYKDKqIPTQKDLADAIINTMLKYkd--kvE-MPNLILEPGRSLVATAGYLLGKVHHI 309 Methanocaldococ...
1HKV_A       241 efgpekTAQIATVDLGGGLGISYLPSDdPPPIAELAAKLGTIVSDEstavglP-TPKLVVEPGRAIAGPGTITLYEVGTV 319 Mycobacterium t...
3N2B_A       319 KHTE-----H-----KNFAIIDAAMNDLIRPALYQAWQDIIPL-R----PRQGEAQTYDLVGPVCETSDFLGKD------ 377 Vibrio cholerae...
P00861       288 KQMG-----S-----RHFVLVDAGFNDLMRPAMYGSYHHISALaAdgrsLEHAPTVETVVAGPLCESGDVFTQQeggnve 357 Escherichia col...
Q58497       314 KETP-----V-----TKWVMIDAGMNDMMRPAMYEAYHHIINCkV----KNEK--EVVSIAGGLCESSDVFGRD------ 371 Methanocaldococ...
O27390       301 KES------Y-----RKFAGVDAGFNTLLRPAMYGSYHHILVAeR----PLDEPSEKMDVAGNVCESGDLFARD------ 359 Methanothermoba...
Q9X1K5       266 KRRH-----N-----KAFVVVDGGMNVLIRPALYSAYHRIFVLgK----QGKE--MRADVVGPLCESGDVIAYD------ 323 Thermotoga mari...
P31848       320 KDVD-----VsatahRRYVSVDGGMSDNIRTALYGAQYDVRLVsR----VSDAPPVPARLVGKHCESGDIIVRD------ 384 Mycobacterium t...
WP_015251780 312 KEVP-----Gv----RQYVAVDGGMNDNIRPALYQAKYEAAAAnR----IGEAHDKTVSIAGKCCESGDMLIWD------ 372 Bacillus subtilis
Q55484       341 KVVP-----Ni----RTYISVDGGMSDNPRPITYQSVYRVALAnR----MNDEITETVTVAGKHCESGDILVKD------ 401 Synechocystis s...
1TWI_A       310 KETP-----V-----TKWVMIDAGMNDMMRPAMYEAYHHIINCkV----KNE--KEVVSIAGGLCESSDVFGRD------ 367 Methanocaldococ...
1HKV_A       320 KDVDvsataH-----RRYVSVDGGMSDNIRTALYGAQYDVRLVsR----VSDAPPVPARLVGKHCESGDIIVRD------ 384 Mycobacterium t...
3N2B_A       378 -RDLV--LQEGDLLAVRSSGAYGFTMSSNYNTRPRVAEVMVDGN-KTYLVRQREELSSLWALES 437 Vibrio cholerae O1 biovar El To...
P00861       358 tRALPe-VKAGDYLVLHDTGAYGASMSSNYNSRPLLPEVLFDNG-QARLIRRRQTIEELLALEL 419 Escherichia coli K-12
Q58497       372 -RELDk-VEVGDVLAIFDVGAYGISMANNYNARGRPRMVLTSKK-GVFLIRERETYADLIAKDI 432 Methanocaldococcus jannaschii D...
O27390       360 -RQLPe-INEGDVLAIMNAGAYSFSMSSQYNSRPRPAEVLVREG-KVDVVRERETFSDLLRGQN 420 Methanothermobacter thermautotr...
Q9X1K5       324 -RELPe-VEPGDIIAVENAGAYGYTMSNNYNSTTRPAEVLVRENgRISLIRRRETEMDIFKDVV 385 Thermotoga maritima MSB8
P31848       385 -TWVPddIRPGDLVAVAATGAYCYSLSSRYNMVGRPAVVAVHAG-NARLVLRRETVDDLLSLEV 446 Mycobacterium tuberculosis
WP_015251780 373 -IDLPe-VKEGDLLAVFCTGAYGYSMANNYNRIPRPAVVFVENG-EAHLVVKRETYEDIVKLDL 433 Bacillus subtilis
Q55484       402 -VALPa-AEPGDIMVVAATGAYNHSMASNYNRLGRPAAVLVNQG-QANLILQRETYTDLLRQDC 462 Synechocystis sp. PCC 6803 subs...
1TWI_A       368 -RELDk-VEVGDVLAIFDVGAYGISMANNYNARGRPRMVLTSKK-GVFLIRERETYADLIAKDI 428 Methanocaldococcus jannaschii
1HKV_A       385 -TWVPddIRPGDLVAVAATGAYCYSLSSRYNMVGRPAVVAVHAG-NARLVLRRETVDDLLSLEV 446 Mycobacterium tuberculosis H37Rv
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap