Conserved Protein Domain Family
PRK06522

?
PRK06522: PRK06522 
2-dehydropantoate 2-reductase; Reviewed
Statistics
?
PSSM-Id: 235821
View PSSM: PRK06522
Aligned: 338 rows
Threshold Bit Score: 200.462
Threshold Setting Gi: 227834057
Created: 9-Dec-2010
Updated: 17-Jan-2013
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
77462099    1 MRICIFGAGAIGGYMGAKLAAAGADVSLVAR----GPHLAAMQARGLTLi---eEGGTRTVPVRAASD--------PAAL 65 
11499285    4 QRVQIMGAGALGSLVGALIQLAGYDVIFVARgkqlEALKKGLRVSGLKN---------AELKVYCTSQ--------PEDA 66 
14520967    1 MKIYILGAGAIGSLFGGLLANAGEDVLLIGR----DPHVSAINEKGLKI--------------VGIKDlnvkveatTRVP 62 
14591192    1 MKIYILGAGAIGSLVGGLLANVGEDVTLIGR----GRHIEAINKRGLMI------EGLTNLKINTKAT--------TSIP 62 
18977768    1 MKIYVLGAGAIGSLFGGLLFAAGEDVVLIGR----KPHVDAINKRGLRI------TGIIEEVIKVPAT--------ISPP 62 
212224616   1 MKIYILGAGSIGSLFGALLTRAGNDVTLI-Gr---EDQVRAINENGLHVlgveefTVYPNASLYAPEE------------ 64 
242399000   1 MKIYILGAGSIGSLFGALLSRVGEDVILIGR----EEHVKEINRNGLKI--------------VGIEEft----vyPEAL 58 
284161230   1 -----MGAGALGCLYGYLLQRK-FEVVFVARgkqfEALKRGLKVTGLVE---------DFVRVNAVDR--------PCDA 57 
288931618   4 FKVQIFGAGALGSLFGALIQHAGFEVHFVARgkqlEALKKSLRVEGLRK-----M--------ELKVD--------VSDK 62 
57641903    1 MRIYVLGAGSIGSLFGALLARAGNDVTLI-Gr---REQVDAINKNGLHVfgaeefTVKPKATIYAPEE------------ 64 
77462099   66 -GPQ----DYVIVTLKAHSVPAVVPQLSRLLGAEGTLVSGVNGlpwwyfhrhggplegrrlesVDPGGVQWDGLGPDRVL 140
11499285   67 --------DITFVTVKAYDTETVAKKLAEVDA--GVVCSLQNG--------------------VGNEEILAK--YCRKVL 114
14520967   63 eEKP----DLIVLATKSYSTIEALKSARHIVKG-SWVLSIQNG--------------------IGNEDKIIE--FGGKAI 115
14591192   63 gAKP----DLIILTTKSYSTDDALNSAKDIVRD-TWVLSLQNG--------------------IGNEEKIME--LGGRPI 115
18977768   63 eEKP----DLIILATKSYSTVEALRASKAIVED-TWILSIQNG--------------------IGNEDEIRK--FGGKPI 115
212224616  65 --PP----DLLILATKSYSTKTALECARNCIGPETWVLSIQNG--------------------LGNEELALKITP--NVM 116
242399000  59 tRMPseppDLIILSTKSHSTEYALECARESIGKNTWILSIQNG--------------------LGNEEEALR--YTKNVL 116
284161230  58 --------DITFVTVKSYDTEEVAKSLRNVDC--GIVVSLQNG--------------------IGNEEILSTYLG--RVL 105
288931618  63 aVDA----DVTFVTVKAYDTEEAAKSLAKVDP--GVVCSLQNG--------------------IGNEEILAE--HLDNVV 114
57641903   65 --PP----DLLILAVKSYSTKTALECARQCIGRNTWVLSIQNG--------------------LGNEELALKYTP--NVM 116
77462099  141 GCVVYPAAEVVEPGAVRHLEGNRFSLGEP-SGEKsdrALrlSEALT----AAGLKAPVRPRLRDEIWVKLWGNLSFNPIS 215
11499285  115 GGVTTYGANLKDYGHVVYAGEGYTYVGEM-DGRV----SgeAEMVAevlrDAGMRAEAVNDIEFRIWAKAVVNAAINPIT 189
14520967  116 GGITTNGAMVEAPGVIKWTGKGVTIIGLY--PQG---KEkfIEKVAdvfnSADIETHVSENIISWIWAKAIVNSAINPIG 190
14591192  116 GGITTNGAVLKEPGVVEWRGRGITLIGLY--PKG---RNefVEEVKetfnRAGLETEVTENIIGWKWAKTIVNSAINPIG 190
18977768  116 GGITTNGAILVSSGVVKWTGKGITVVGLY--PKG---RHtfVDKISeifnRAGLETIVSENIEGWIWAKAIVNSAINPIG 190
212224616 117 GGITTNGAMLVGWGRVKWTGRGITVVGKYpTGTH---PF--VEEVAetfnGAGIETHTTENVIGWKWAKAIVNSVINGLG 191
242399000 117 GGITTNGAMIERWGVVKWVGRGITIIGDY-PRGI---SPftAELIEif-nKAGLKTELSENIEGWKWSKAIVNSAINPIG 191
284161230 106 GGVTTYASNLIDYGWIEFAGVGETFIGSM-DGKI---CEdvLVVVEvl-rECGINAEAVSDIVRRKWIKTVINSVINPIT 180
288931618 115 GGVTTYGANLKDFGVVVFAGEGVTYIGEF-KGKG-------IEKVErvlkDSGINVEVVEDIKEKIWEKAVVNSVINPIT 186
57641903  117 GGVTTNGAMLVEWGKVLWAGKGITVIGRYpTGRD---DF--VDEVAsvfnEAGIDTSVTENAIGWKWAKAIVNSVINGLG 191
77462099  216 ALTGATLDRLCTDPGTRAVARSMMLEAQAIAERLGGQVshrcGAPHRRGRSRRCapDVdAAGSRSRAADgdrgaggvrgg 295
11499285  190 AICRVKNGEVVRNPHLWEVARAVADEGRQVMARMGYEFd---AASEVRKVAEMT-----AENRSSMLQD----------- 250
14520967  191 TLLEVKNKVIRENDFLLSMAMEVVKEGCRVALQNGIEF----DVPPMDLFFQTLeqTR--ENYNSMLQD----------- 253
14591192  191 AILEVKNGAIKDNDYLLSIAVEVVKEGCKIALQNGIKF----DISPMELLIQTLeqTR--ENYNSMLQD----------- 253
18977768  191 TLLRVKNGAILDNEELLSVAVEVVKEGCKVATQNGVKL----EVHPIDLLFQTLkkTR--ENYNSMLQD----------- 253
212224616 192 TVLEVKNGFLKDDPYLEGISVDIAREGCTVARQLGIEF----EIHPLELLWDTIe-KT-RENYNSTLQD----------- 254
242399000 192 AIMEVKNVKILENEYLLKLAKEVVKEGCQVATQLGVKF----EKHPMELLIETLeqTR--ENYNSMLQD----------- 254
284161230 181 AILRVRNGAIVEIEELWKLASAVLREGEEVLKAMGFDV-------ELEEVLKDVvtKT-ARNRSSMLQD----------- 241
288931618 187 AIFRVKNGEILRNEFLWEIAKKTAKESEEVAREVGYEI-------NAVEAVKIVaeKT-AENISSMLQD----------- 247
57641903  192 TVLEVKNGHLKDDPHLEGISVDIAREGCMVAQQLGIEF----EIHPLELLWDTIe-RT-RENYNSTLQD----------- 254
77462099  296 twphrepadahhrhgagngaapgkgggsdlsawpVGCGKAgGSAPGPPGYLGQNERARGASDPrvpgrglpredvsrrtd 375
11499285  251 ----------------------------------LERGKR-TEVEFINGAIVKKGEEFGIDCA----------------- 278
14520967  254 ----------------------------------IWRGKK-TEVDYINGKIVEYAKAVNLEAP----------------- 281
14591192  254 ----------------------------------IWRGKR-TEIDFINGKIIEYAKLVNLEAP----------------- 281
18977768  254 ----------------------------------ILKGRK-TEIDYINGKIVEYAKSVGLEAP----------------- 281
212224616 255 ----------------------------------IKRRKR-TEVDYIHGKIVEYARSVGLEAP----------------- 282
242399000 255 ----------------------------------IRRKKK-TEIDFINGKIIEYGRKIGLEVP----------------- 282
284161230 242 ----------------------------------IERGKR-TEIDFINGAIVRKAEELGIDTP----------------- 269
288931618 248 ----------------------------------VMKGRK-TEIDFINGVIVKEGEKRGLDVC----------------- 275
57641903  255 ----------------------------------IWRGRE-TEVDYIHGKIVEYARSVGMEAP----------------- 282
77462099  376 llcpggpgeaagsraraaglgprhgrlgwSARHSLPIFTLEKYPRGVR 423
11499285  279 -----------------------------VNRTLLNLVRGVESGL--- 294
14520967  282 -----------------------------MNLLLWGLIKGKEALEGKK 300
14591192  282 -----------------------------LNFLLWALVKAKESLGGGS 300
18977768  282 -----------------------------LNFLLWGLIKGMEKLHGGV 300
212224616 283 -----------------------------RNELLWALIKAKE-EQSR- 299
242399000 283 -----------------------------LNFALWSMVKAKEIPQTK- 300
284161230 270 -----------------------------YNRALLLLVKSLEKFLTKC 288
288931618 276 -----------------------------YNSFLWRAVKAIEKVRG-- 292
57641903  283 -----------------------------RNELLWVLVKAKE-RINRG 300
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap