15236282 24 DEEAKASLDIWKYVFGFADIAAAKCAIDLKIPEAIENHP----SSQPVTLAELsSAVSASPSHLRRIMRFLVHQGIFKEI 99 thale cress 7303836 1 ----------------------------------------------------------MTTTLEEQLSDKLQMMDETTDK 22 fruit fly 15236280 10 DEEAKASLDIWRYVFGFADIAAAKCAIDLKIPEAIENHP----SSQPVTLSELsSAVSASPSHLRRIMRFLVHQGLFKEV 85 thale cress 17510631 -------------------------------------------------------------------------------- Caenorhabditis elegans 18548761 1 -----MAHRGAHFAFRSRWQKTDDELCRHSMSFILHKAIrndfFQSYLYLLEKiPLGKSDTYLSFWDFFSLDSWLITSSF 75 human 4757792 3 SSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPg---PLDVAAVAAG--VR-ASAHGTELLLDICVSLKLLKVE 76 human 3808149 221 etlppFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEA----PQKAADIAS---KVDASACGMERLLDICAAMGLLEKT 293 human 7661528 -------------------------------------------------------------------------------- human 3183316 -------------------------------------------------------------------------------- fission yeast 586379 -------------------------------------------------------------------------------- baker's yeast
15236282 100 PTKdgLAtGYVNTPLSRRLMITRRd--GKSLAPFVLFETTPEMLAPWLRLSSVVSSPVNgstppPFDAVHG-KDVWSFAQ 176 thale cress 7303836 23 VQG-------SSKQKDDSSIAASSd--AKTASPSSSDSSTKVAAPESEFYNKAQKYWSE-----VPATVNG--MLGGLGY 86 fruit fly 15236280 86 PTKdgLAtGYTNTPLSRRMMITK---------------------------------------------LHG-KDLWAFAQ 119 thale cress 17510631 1 ----------------------------------MSSSSSSRIHNGEDVYEKAEEYWSR-----ASQDVNG--MLGGFEA 39 Caenorhabditis elegans 18548761 76 IVH-----LLLIVTLIGLEYSFKKllkNESIGVKLYALTSQVINGEMQFYARAKLFYQE-----VPATEEG--MMGNFIE 143 human 4757792 77 TRG--GKaFYRNTELSSDYLTTVS----PTSQCSMLKYMGRTSYRCWGHLADAVREGRN-----QYLETFG-VPAEELFT 144 human 3808149 294 EQG------YSNTETANVYLASDG---EYSLHGFIMHN-NDLTWNLFTYLEFAIREGTN-----QHHRALGkKAEDLFQD 358 human 7661528 1 -------------------------------------MTSEVIEDEKQFYSKAKTYWKQ-----IPPTVDG--MLGGYGH 36 human 3183316 1 -------------------------------------------MDPEKFYSDAIDYWNG-----VQPTVDG--MLGGLGT 30 fission yeast 586379 1 ---------------------------------------MDVPADSHIKYEDAIDYWTD-----VDATVDG--VLGGYGE 34 baker's yeast
15236282 177 DNPFLSDMINEAMACDARRVVPRVAGACHGl-FDGVTTMVDVG----------------------------GGTGETMGM 227 thale cress 7303836 87 ISA---IDIQGSNVFLREIRVP-------G-----NRLALDCG----------------------------AGIGRVTRN 123 fruit fly 15236280 120 DNLCHSQLINEAMACDARRVVPRVAGACQGl-FDGVATVVDVG----------------------------GGTGETMGI 170 thale cress 17510631 40 LHA---PDISASKRFIEGLKK----KNLFG----YFDYALDCG----------------------------AGIGRVTKH 80 Caenorhabditis elegans 18548761 144 LSS---PDIQASQKFLRKFVG---GPGRAG-----TDCALDCG----------------------------SGIGRVSKH 184 human 4757792 145 AIYRSEGERLQFMQALQEVWSVNGRSVLTAfdLSVFPLMCDLGgtrikletiilsklsqgqktkhrvfsliGGAGALAKE 224 human 3808149 359 AYYQSPETRLRFMRAMHGMTKLTACQVATAfnLSRFSSACDVG----------------------------GCTGALARE 410 human 7661528 37 ISSS--IDINSSRKFLQRFLRE--GPNKTG-----TSCALDCG----------------------------AGIGRITKR 79 human 3183316 31 G-RIPQTDVVGSRTFLNRLNY-RIGKIEN-------LVAADCG----------------------------AGIGRVTEN 73 fission yeast 586379 35 GTVVPTMDVLGSNNFLRKLKS-RMLPQENN-----VKYAVDIG----------------------------AGIGRVSKT 80 baker's yeast
15236282 228 LVK-EFPWIKGFNFDLPHVIEVAEVL--DG-----VENVEGDMFDS-IPACD---AIFIKWVLHDWGDKDCIKILKNCKE 295 thale cress 7303836 124 LLIpRFSCVDLVEQDPAFADKAREYCtsEDgsrgkVGQIYNVGLQKfTPTQQy-dLVWTQWVLGHLTDRDLVSFFRRIKQ 202 fruit fly 15236280 171 LVK-EFPWIKGFNFDLPHVIEVAQVL--DG-----VENVEGDMFDS-IPASD---AVIIKWVLHDWGDKDCIKILKNCKE 238 thale cress 17510631 81 LLMpFFSKVDMEDVVEELITKSDQYIgkHPr----IGDKFVEGLQTfAPPERrydLIWIQWVSGHLVDEDLVDFFKRCAK 156 Caenorhabditis elegans 18548761 185 VLLpVFNSVELVDMMESFLLEAQNYLq--------VK--------------------------GHLTDKDLLAFLSRCRD 230 human 4757792 225 CMS-LYPGCKITVFDIPEVVWTAKQHfsFQee-eqIDFQEGDFFKDpLPEAD---LYILARVLHDWADGKCSHLLERIYH 299 human 3808149 411 LAR-EYPRMQVTVFDLPDIIELAAHFqpPGpqavqIHFAAGDFFRDpLPSAE---LYVLCRILHDWPDDKVHKLLSKVAE 486 human 7661528 80 LLLpLFREVDMVDITEDFLVQAKTYLgeEGk---rVRNYFCCGLQDfTPEPDsydVIWIQWVIGHLTDQHLAEFLRRCKG 156 human 3183316 74 VLLkIASHVDLVEPVENFISTAKKQLatKP------CSFINVGLQNwTPEKNrygLIWNQWCLSHLTDEDLIAYLSRCCE 147 fission yeast 586379 81 MLHkHAAKIDLVEPVKPFIEQMHVELaeLKdk-gqIGQIYEVGMQDwTPDAGkywLIWCQWCVGHLPDAELVAFLKRCIV 159 baker's yeast
15236282 296 AVPPnIGKVLIVESVIGEnkktmiVDERDEKLEHVRLMLDMVMMAHTSTGKERTLKEWDFVLKEAGFARYEVRDIDDVQS 375 thale cress 7303836 203 GLAP-GAFLCLKENVSSSk-----KTVEDRNDSSVTRPLDSYEHFLKEAGFRIVRKVKQQNFPKGLFPVYMIACKPVSKE 276 fruit fly 15236280 239 AVLPnIGKVLIVECVIGEkkntmiAEERDDKLEHVRLQLDMVMMVHTSTGKERTLKEWDFVLTEAGFARYEVRDFDDVQS 318 thale cress 17510631 157 GLKP-GGCIVLKDNVTNHe-----KRLFDDDDHSWTRTEPELLKAFADSQLDMVSKALQTGFPKEIYPVKMYALKPQHTG 230 Caenorhabditis elegans 18548761 231 GLKE-NGIIILKDN-VARe-----GCILDLSDSSVTRDMDILRSLIRKSGLVVLGQEKQDGFPEQCIPVWMFALHSDRHS 303 human 4757792 300 TCKP-GGGILVIESLLDE-------DRRG---PLLTQLYSLNMLVQTE-GQERTPTHYHMLLSSAGFRDFQFKKTGAIYD 367 human 3808149 487 SCKP-GAGLLLVETLLDE-------EKR---VAQRALMQSLNMLVQTE-GKERSLGEYQCLLELHGFHQVQVVHLGGVLD 554 human 7661528 157 SLRP-NGIIVIKDN-MAQe-----GVILDDVDSSVCRDLDVVRRIICSAGLSLLAEERQENLPDEIYHVYSFALR----- 224 human 3183316 148 AIQE-KGVICVKEN-VSSf-----EDTFDPIDSSVTRCEQSLKSLFKKANLVVVAETLQHGFPEELFPVKMYALVPHSS- 219 fission yeast 586379 160 GLQP-NGTIVVKENNTPTd-----TDDFDETDSSVTRSDAKFRQIFEEAGLKLIASERQRGLPRELYPVRMYALKPMPN- 232 baker's yeast
15236282 376 LIIAYR 381 thale cress 7303836 ------ fruit fly 15236280 319 LIIAYR 324 thale cress 17510631 231 FTNN-- 234 Caenorhabditis elegans 18548761 ------ human 4757792 368 AILARK 373 human 3808149 555 AILPPK 560 human 7661528 ------ human 3183316 ------ fission yeast 586379 ------ baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",