18491016 1 MGIQGLLQFIKE--ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPT--DRYVGFCMKFVNMLLSHGIKPILV 76 human 7298467 1 MGITGLIPFVGK--ASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEKLARGEDT--DVYIQYCLKYVNMLLSYDIKPILV 76 fruit fly 30685678 4 kdllrfmkpyilpihiqkyagkrvgidayswlhkgayscsMELCLDTDGKKK----LRYIDYFMHRVNLLQHYEIIPVVV 79 thale cress 15220506 1 MGIQGLLPLLKS--IMVPIHIKELEGCIVAVDTYSWLHKGALSCSRELCKGLPT--KRHIQYCMHRVNLLRHHGVKPIMV 76 thale cress 7487810 1 MGFTSLYSLYGKskVLKSISFSALNSKTLAIDASMWLYRGALNNARKFLEEPTTpnSEHIMFVIKKVKQFIDRNVNPILV 80 thale cress 17553464 1 MGISGLLPFVKN--ACRKGNILELRGKSVAIDVSCLLHRGLTGCMDKIHMGEET--QSYVNYVNKYVKELLGMGCHVVMV 76 Caenorhabditis elegans 19074876 1 MGISGLLPIVAP--KLVKKHISSYKRQRVGVDGHAWLYQILPCVAEEMFFKVPT--KRHVDLFEEKVKLLESYGIIPVIV 76 Encephalitozoon cun... 18491018 1 MGIQGLLQFIKE--ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPT--DRYVGFCMKFVNMLLSHGIKPILV 76 human 18491020 1 MGIQGLLQFIKE--ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPT--DRYVGFCMKFVNMLLSHGIKPILV 76 human 1706728 1 MGIKGLLGLLKP--MQKSSHVEEFSGKTLGVDGYVWLHKAVFTCAHELAFNKET--DKYLKYAIHQALMLQYYGVKPLIV 76 fission yeast 2501673 1 MGIPGLLPQLKR--IQKQVSLKKYMYQTLAIDGYAWLHRASCACAFELVMNKPT--NKYLQFFIKRLQLLKRLKIKPYIV 76 baker's yeast 1706421 1 MGIQGLLPQLKP--IQNPVSLRRYEGEVLAIDGYAWLHRAACSCAYELAMGKPT--DKYLQFFIKRFSLLKTFKVEPYLV 76 baker's yeast 7298467 1 MGITGLIPFVGK--ASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEKLARGEDT--DVYIQYCLKYVNMLLSYDIKPILV 76 fruit fly 30685678 4 kdllrfmkpyilpihiqkyagkrvgidayswlhkgayscsMELCLDTDGKKK----LRYIDYFMHRVNLLQHYEIIPVVV 79 thale cress 15220506 1 MGIQGLLPLLKS--IMVPIHIKELEGCIVAVDTYSWLHKGALSCSRELCKGLPT--KRHIQYCMHRVNLLRHHGVKPIMV 76 thale cress 7487810 1 MGFTSLYSLYGKskVLKSISFSALNSKTLAIDASMWLYRGALNNARKFLEEPTTpnSEHIMFVIKKVKQFIDRNVNPILV 80 thale cress 17553464 1 MGISGLLPFVKN--ACRKGNILELRGKSVAIDVSCLLHRGLTGCMDKIHMGEET--QSYVNYVNKYVKELLGMGCHVVMV 76 Caenorhabditis elegans 19074876 1 MGISGLLPIVAP--KLVKKHISSYKRQRVGVDGHAWLYQILPCVAEEMFFKVPT--KRHVDLFEEKVKLLESYGIIPVIV 76 Encephalitozoon cun... 18491018 1 MGIQGLLQFIKE--ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPT--DRYVGFCMKFVNMLLSHGIKPILV 76 human 18491020 1 MGIQGLLQFIKE--ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPT--DRYVGFCMKFVNMLLSHGIKPILV 76 human 1706728 1 MGIKGLLGLLKP--MQKSSHVEEFSGKTLGVDGYVWLHKAVFTCAHELAFNKET--DKYLKYAIHQALMLQYYGVKPLIV 76 fission yeast 2501673 1 MGIPGLLPQLKR--IQKQVSLKKYMYQTLAIDGYAWLHRASCACAFELVMNKPT--NKYLQFFIKRLQLLKRLKIKPYIV 76 baker's yeast 1706421 1 MGIQGLLPQLKP--IQNPVSLRRYEGEVLAIDGYAWLHRAACSCAYELAMGKPT--DKYLQFFIKRFSLLKTFKVEPYLV 76 baker's yeast
18491016 77 FDGCTLPSKKEVERSRRERRQANLLKGKQLLR------EGKVSEARECFTRSINITHAMAHKVIKAARSQ-GVDCLVAPY 149 human 7298467 77 FDGQHLPAKALTEKRRRDSRKQSKERAAELLR------LGRIEEARSHMRRCVDVTHDMALRLIRECRSR-NVDCIVAPY 149 fruit fly 30685678 80 LDGGNMPCKAATGDERHRQRKANFDAAMVKLK------EGNVAAATELFQRAVSVTSSMAHQLIQVLKSE-NVEFIVAPY 152 thale cress 15220506 77 FDGGPLPMKLEQENKRARSRKENLARALEHEA------NGNSSAAYECYSKAVDISPSIAHELIQVLRQE-NVDYVVAPY 149 thale cress 7487810 81 FDGHRLPIKSPRNPIKTLEYAKDLDASAQLMApddpkrKDKEKNATKIFQSHIHITPYVIHVFIEYVYNQvIEELQHLNV 160 thale cress 17553464 77 FDGRPLPAKKGTNEERRELREKRKEHAEMLLA------KGLEREARDTYRLATSISADIVENTIQYFRSMtNVDIVVAPY 150 Caenorhabditis elegans 19074876 77 LDGDLLSSKEETNRKRRIRKEKSRKEAEYWLM------RNDPAKAKGFMRQCIAVTREVVSDIARMLERI-NVEYIISPY 149 Encephalitozoon cun... 18491018 77 FDGCTLPSKKEVERSRRERRQANLLKGKQLLR------EGKVSEARECFTRSINITHAMAHKVIKAARSQ-GVDCLVAPY 149 human 18491020 77 FDGCTLPSKKEVERSRRERRQANLLKGKQLLR------EGKVSEARECFTRSINITHAMAHKVIKAARSQ-GVDCLVAPY 149 human 1706728 77 FDGGPLPCKASTEQKRKERRQEAFELGKKLWD------EGKKSQAIMQFSRCVDVTPEMAWKLIIALREH-GIESIVAPY 149 fission yeast 2501673 77 FDGDSLFVKNHTETRRRKKRLENEMIAKKLWS------AGNRYNAMEYFQKSVDITPEMAKCIIDYCKLH-SIPYIVAPF 149 baker's yeast 1706421 77 FDGDAIPVKKSTESKRRDKRKENKAIAERLWA------CGEKKNAMDYFQKCVDITPEMAKCIICYCKLN-GIRYIVAPF 149 baker's yeast 7298467 77 FDGQHLPAKALTEKRRRDSRKQSKERAAELLR------LGRIEEARSHMRRCVDVTHDMALRLIRECRSR-NVDCIVAPY 149 fruit fly 30685678 80 LDGGNMPCKAATGDERHRQRKANFDAAMVKLK------EGNVAAATELFQRAVSVTSSMAHQLIQVLKSE-NVEFIVAPY 152 thale cress 15220506 77 FDGGPLPMKLEQENKRARSRKENLARALEHEA------NGNSSAAYECYSKAVDISPSIAHELIQVLRQE-NVDYVVAPY 149 thale cress 7487810 81 FDGHRLPIKSPRNPIKTLEYAKDLDASAQLMApddpkrKDKEKNATKIFQSHIHITPYVIHVFIEYVYNQvIEELQHLNV 160 thale cress 17553464 77 FDGRPLPAKKGTNEERRELREKRKEHAEMLLA------KGLEREARDTYRLATSISADIVENTIQYFRSMtNVDIVVAPY 150 Caenorhabditis elegans 19074876 77 LDGDLLSSKEETNRKRRIRKEKSRKEAEYWLM------RNDPAKAKGFMRQCIAVTREVVSDIARMLERI-NVEYIISPY 149 Encephalitozoon cun... 18491018 77 FDGCTLPSKKEVERSRRERRQANLLKGKQLLR------EGKVSEARECFTRSINITHAMAHKVIKAARSQ-GVDCLVAPY 149 human 18491020 77 FDGCTLPSKKEVERSRRERRQANLLKGKQLLR------EGKVSEARECFTRSINITHAMAHKVIKAARSQ-GVDCLVAPY 149 human 1706728 77 FDGGPLPCKASTEQKRKERRQEAFELGKKLWD------EGKKSQAIMQFSRCVDVTPEMAWKLIIALREH-GIESIVAPY 149 fission yeast 2501673 77 FDGDSLFVKNHTETRRRKKRLENEMIAKKLWS------AGNRYNAMEYFQKSVDITPEMAKCIIDYCKLH-SIPYIVAPF 149 baker's yeast 1706421 77 FDGDAIPVKKSTESKRRDKRKENKAIAERLWA------CGEKKNAMDYFQKCVDITPEMAKCIICYCKLN-GIRYIVAPF 149 baker's yeast
18491016 150 EADAQLAYLN----KAGIVQAIITEDSDLLAFGCKKVILKMDQ-FGNGLEI---DQARLGMCR--QLG-DVFTEEKFRYM 218 human 7298467 150 EADAQMAWLN----RADVAQYIITEDSDLTLFGAKNIIFKLDL-NGSGLLV---EAEKLHLAM--GCTeEKYHFDKFRRM 219 fruit fly 30685678 153 EADAQLAYLSslelEQGGIAAVITEDSDLLAYGCKAVIFKMDR-YGKGEELvldNVFQAVDQK--PSF-QNFDQELFTAM 228 thale cress 15220506 150 EADAQMAFLA----ITKQVDAIITEDSDLIPFGCLRIIFKMDK-FGHGVEF---QASKLPKNK--DLSlSGFSSQMLLEM 219 thale cress 7487810 161 PEVSNLPFLRd---RESGDEFVIRKALSSPQLPPPPNRNSRRStPSPALPP---SISSSQVT------------------ 216 thale cress 17553464 151 EADAQLAYLV----QEKLVDAVITEDSDLIVFGCEMIYFKWQSaTGECSVY---EKCNLKNCFtgELGgDKFDFVKFRRI 223 Caenorhabditis elegans 19074876 150 ESDAQLCFLQ----RIGYIDCILTEDSDLIPYGSSKVLYKFD--SAFVQEF---NRECLSEVK--GKD----FEENILDI 214 Encephalitozoon cun... 18491018 150 EADAQLAYLN----KAGIVQAIITEDSDLLAFGCKKVILKMDQ-FGNGLEI---DQARLGMCR--QLG-DVFTEEKFRYM 218 human 18491020 150 EADAQLAYLN----KAGIVQAIITEDSDLLAFGCKKVILKMDQ-FGNGLEI---DQARLGMCR--QLG-DVFTEEKFRYM 218 human 1706728 150 EADAQLVYLE----KENIIDGIITEDSDMLVFGAQTVLFKMDG-FGNCITI---RRNDIANAQ--DLN-LRLPIEKLRHM 218 fission yeast 2501673 150 EADPQMVYLE----KMGLIQGIISEDSDLLVFGCKTLITKLND-QGKALEIskdDFSALPENF--PLG--ELSEQQFRNL 220 baker's yeast 1706421 150 EADSQMVYLE----QKNIVQGIISEDSDLLVFGCRRLITKLND-YGECLEIcrdNFIKLPKKF--PLG--SLTNEEIITM 220 baker's yeast 7298467 150 EADAQMAWLN----RADVAQYIITEDSDLTLFGAKNIIFKLDL-NGSGLLV---EAEKLHLAM--GCTeEKYHFDKFRRM 219 fruit fly 30685678 153 EADAQLAYLSslelEQGGIAAVITEDSDLLAYGCKAVIFKMDR-YGKGEELvldNVFQAVDQK--PSF-QNFDQELFTAM 228 thale cress 15220506 150 EADAQMAFLA----ITKQVDAIITEDSDLIPFGCLRIIFKMDK-FGHGVEF---QASKLPKNK--DLSlSGFSSQMLLEM 219 thale cress 7487810 161 PEVSNLPFLRd---RESGDEFVIRKALSSPQLPPPPNRNSRRStPSPALPP---SISSSQVT------------------ 216 thale cress 17553464 151 EADAQLAYLV----QEKLVDAVITEDSDLIVFGCEMIYFKWQSaTGECSVY---EKCNLKNCFtgELGgDKFDFVKFRRI 223 Caenorhabditis elegans 19074876 150 ESDAQLCFLQ----RIGYIDCILTEDSDLIPYGSSKVLYKFD--SAFVQEF---NRECLSEVK--GKD----FEENILDI 214 Encephalitozoon cun... 18491018 150 EADAQLAYLN----KAGIVQAIITEDSDLLAFGCKKVILKMDQ-FGNGLEI---DQARLGMCR--QLG-DVFTEEKFRYM 218 human 18491020 150 EADAQLAYLN----KAGIVQAIITEDSDLLAFGCKKVILKMDQ-FGNGLEI---DQARLGMCR--QLG-DVFTEEKFRYM 218 human 1706728 150 EADAQLVYLE----KENIIDGIITEDSDMLVFGAQTVLFKMDG-FGNCITI---RRNDIANAQ--DLN-LRLPIEKLRHM 218 fission yeast 2501673 150 EADPQMVYLE----KMGLIQGIISEDSDLLVFGCKTLITKLND-QGKALEIskdDFSALPENF--PLG--ELSEQQFRNL 220 baker's yeast 1706421 150 EADSQMVYLE----QKNIVQGIISEDSDLLVFGCRRLITKLND-YGECLEIcrdNFIKLPKKF--PLG--SLTNEEIITM 220 baker's yeast
18491016 219 CILSGCDYLSS-LRGIGLAKACKVLRLANNPDIVKvi-kkIGHYLKMNI--TVPEDYINGFIRANNTFLYQLVFDPIKRK 294 human 7298467 220 CILSGCDYLDS-LPGIGLAKACKFILKTEQEDMRIalkkiPSYLNMRNL--EVDDDYIENFMKAEATFRHMFIYNPLERR 296 fruit fly 30685678 229 CVLAGCDFLPS-VPGVGISRAHAFISKYQSVELVL-----SFLKTKKGK--LVPDDYSSSFTEAVSVFQHARVYDFDAKK 300 thale cress 15220506 220 CILSGCDYLQS-LPGMGLKRAHALITKFKSYDRV------IKHLKYSTV--SVPPLYEESFKRALLTFKHQRVYDPNAED 290 thale cress 7487810 -------------------------------------------------------------------------------- thale cress 17553464 224 CILSGCDYLQAgLPGVGLSTAAKFFSMTSIKDLRTllrkvPSYLKNPKLkeHVNDEFIRNFEKAENTFKHQIVFDPRERC 303 Caenorhabditis elegans 19074876 215 SILSGCDYLAS-IQGVGVVTAHRLLSREKTVERVV-----E--YLKYRK--PVPSSYLEDFSRAKKTFLHQIVYDPIQKR 284 Encephalitozoon cun... 18491018 219 CILSGCDYLSS-LRGIGLAKACKVLRLANNPDIVKvi-kkIGHYLKMNI--TVPEDYINGFIRANNTFLYQLVFDPIKRK 294 human 18491020 219 CILSGCDYLSS-LRGIGLAKACKVLRLANNPDIVKvi-kkIGHYLKMNI--TVPEDYINGFIRANNTFLYQLVFDPIKRK 294 human 1706728 219 AIFSGCDYTDG-VAGMGLKTALRYLQKYPEPRAAIr----A-MRLDKSL--KVPVSFEKEFALADLAFRHQRVYCPKDKT 290 fission yeast 2501673 221 VCLAGCDYTSG-IWKVGVVTAMKIVKRYSEMKDIL-----IQIERTEKL--CFSKAFKQQVEFANYAFQYQRVFCPLSNQ 292 baker's yeast 1706421 221 VCLSGCDYTNG-IPKVGLITAMKLVRRFNTIERII-----LSIQREGKL--MIPDTYINEYEAAVLAFQFQRVFCPIRKK 292 baker's yeast 7298467 220 CILSGCDYLDS-LPGIGLAKACKFILKTEQEDMRIalkkiPSYLNMRNL--EVDDDYIENFMKAEATFRHMFIYNPLERR 296 fruit fly 30685678 229 CVLAGCDFLPS-VPGVGISRAHAFISKYQSVELVL-----SFLKTKKGK--LVPDDYSSSFTEAVSVFQHARVYDFDAKK 300 thale cress 15220506 220 CILSGCDYLQS-LPGMGLKRAHALITKFKSYDRV------IKHLKYSTV--SVPPLYEESFKRALLTFKHQRVYDPNAED 290 thale cress 7487810 -------------------------------------------------------------------------------- thale cress 17553464 224 CILSGCDYLQAgLPGVGLSTAAKFFSMTSIKDLRTllrkvPSYLKNPKLkeHVNDEFIRNFEKAENTFKHQIVFDPRERC 303 Caenorhabditis elegans 19074876 215 SILSGCDYLAS-IQGVGVVTAHRLLSREKTVERVV-----E--YLKYRK--PVPSSYLEDFSRAKKTFLHQIVYDPIQKR 284 Encephalitozoon cun... 18491018 219 CILSGCDYLSS-LRGIGLAKACKVLRLANNPDIVKvi-kkIGHYLKMNI--TVPEDYINGFIRANNTFLYQLVFDPIKRK 294 human 18491020 219 CILSGCDYLSS-LRGIGLAKACKVLRLANNPDIVKvi-kkIGHYLKMNI--TVPEDYINGFIRANNTFLYQLVFDPIKRK 294 human 1706728 219 AIFSGCDYTDG-VAGMGLKTALRYLQKYPEPRAAIr----A-MRLDKSL--KVPVSFEKEFALADLAFRHQRVYCPKDKT 290 fission yeast 2501673 221 VCLAGCDYTSG-IWKVGVVTAMKIVKRYSEMKDIL-----IQIERTEKL--CFSKAFKQQVEFANYAFQYQRVFCPLSNQ 292 baker's yeast 1706421 221 VCLSGCDYTNG-IPKVGLITAMKLVRRFNTIERII-----LSIQREGKL--MIPDTYINEYEAAVLAFQFQRVFCPIRKK 292 baker's yeast
18491016 295 LIPLNAYEDDVDP---ETLSYAGQYVDDSIALQIA--LGNKDINTFEQIDDYNPDTAMPAHSRSHSWDd-KTCQKSANVS 368 human 7298467 297 MQRLCALEDYETDe-rYCSNAGTLLEDSEQALHLA--LGNLNPFSMKRLDSWTPEKAWPTPKNVKRSK--HKSIWQTNFQ 371 fruit fly 30685678 301 LKHLKPLSHNLLNlpvEQLEFLGPDLSPSVAVAIA--EGNVDPITMKAFNHFSVS-RKPLKTPVRSFK---EQEKGSSFL 374 thale cress 15220506 291 IIHLCDISDNLG----EDSDFVGPYPLRQVF------------------------------------------------- 317 thale cress 7487810 -------------------------------------------------------------------------------- thale cress 17553464 304 QKPLTPYPKEVLMtgvDDLEEVIDLDSPKKTAPSSksFAYAGTASTQRIAIRLALGNPENKSSIDDQFllVQPTPEWSVW 383 Caenorhabditis elegans 19074876 285 RRHLQDAGEKLD--------FLGTLKEEEYVVESA--LPELFFKPSSRAKAIKRHFIPLARREGSEELeaRRDKRERHSQ 354 Encephalitozoon cun... 18491018 295 LIPLNAYEDDVDP---ETLSYAGQYVDDSIALQIA--LGNKDINTFEQIDDYNPDTAMPAHSRSRSWDd-KTCQKSANVS 368 human 18491020 295 LIPLNAYEDDVDP---ETLSYAGQYVDDSIALQIA--LGNKDINTFEQIDDYNPDTAMPAHSRSRSWDd-KTCQKSANVS 368 human 1706728 291 LVHLSPPERELSV---HEDAFIGSFFDNQLAIDIA--EGRSNPITKCAFDIKDSSMQSFTKTTITISK--RKGISKTDIS 363 fission yeast 2501673 293 ITTLNNIPKAVTN---SHAEIIKIMKCIGSVVERG--SGVRKDVINTKNIDHKVH-EMIAKGELHPVD---MASKLINR- 362 baker's yeast 1706421 293 IVSLNEIPLYLKD---TESKRKRLYACIGFVIHRE--TQKKQIVHFDDDIDHHLH-LKIAQGDLNPYD---FHQPLANR- 362 baker's yeast 7298467 297 MQRLCALEDYETDe-rYCSNAGTLLEDSEQALHLA--LGNLNPFSMKRLDSWTPEKAWPTPKNVKRSK--HKSIWQTNFQ 371 fruit fly 30685678 301 LKHLKPLSHNLLNlpvEQLEFLGPDLSPSVAVAIA--EGNVDPITMKAFNHFSVS-RKPLKTPVRSFK---EQEKGSSFL 374 thale cress 15220506 291 IIHLCDISDNLG----EDSDFVGPYPLRQVF------------------------------------------------- 317 thale cress 7487810 -------------------------------------------------------------------------------- thale cress 17553464 304 QKPLTPYPKEVLMtgvDDLEEVIDLDSPKKTAPSSksFAYAGTASTQRIAIRLALGNPENKSSIDDQFllVQPTPEWSVW 383 Caenorhabditis elegans 19074876 285 RRHLQDAGEKLD--------FLGTLKEEEYVVESA--LPELFFKPSSRAKAIKRHFIPLARREGSEELeaRRDKRERHSQ 354 Encephalitozoon cun... 18491018 295 LIPLNAYEDDVDP---ETLSYAGQYVDDSIALQIA--LGNKDINTFEQIDDYNPDTAMPAHSRSRSWDd-KTCQKSANVS 368 human 18491020 295 LIPLNAYEDDVDP---ETLSYAGQYVDDSIALQIA--LGNKDINTFEQIDDYNPDTAMPAHSRSRSWDd-KTCQKSANVS 368 human 1706728 291 LVHLSPPERELSV---HEDAFIGSFFDNQLAIDIA--EGRSNPITKCAFDIKDSSMQSFTKTTITISK--RKGISKTDIS 363 fission yeast 2501673 293 ITTLNNIPKAVTN---SHAEIIKIMKCIGSVVERG--SGVRKDVINTKNIDHKVH-EMIAKGELHPVD---MASKLINR- 362 baker's yeast 1706421 293 IVSLNEIPLYLKD---TESKRKRLYACIGFVIHRE--TQKKQIVHFDDDIDHHLH-LKIAQGDLNPYD---FHQPLANR- 362 baker's yeast
18491016 369 SIWHRNYSPrpesgtvSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYslsftkktkKNSSE 448 human 7298467 372 --SENTHTPkkenpcaLFFKKVDFVGKTLNEEIEANQRLEQAKQTEAELFNMYSFKAKRRRSPSREdsv---dqeRTPPP 446 fruit fly 30685678 375 VCSLSKSEE-------IIELKRTADEAMIDPEAIVKKKMYSKQDSDLYKLLAQPNRDQVVTRPSNPsl-----ipDNNPF 442 thale cress 15220506 -------------------------------------------------------------------------------- thale cress 7487810 -------------------------------------------------------------------------------- thale cress 17553464 384 GLRYESKGStldkiskQKELEATQCGGAFKLDSPSVKRVKVASKTTPNDDEDDIVKQFMADIEKEKka------iKKRKN 457 Caenorhabditis elegans 19074876 355 RVDMHTHSPyfk-------------------------------------------------------------------- 366 Encephalitozoon cun... 18491018 369 SIWHRNYSPrpesgtvSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYslsftkktkKNSSE 448 human 18491020 369 SIWHRNYSPrpesgtvSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYslsftkktkKNSSE 448 human 1706728 364 NFFMKSIPP---------SKRPTKSTSLIDVTNVKVQRTHLANDISSEKQSIKSANEKAYVTPKSN---------SLKPG 425 fission yeast 2501673 363 --ERKLKARk------LFKVGLLGGES-----NSFNKKVEQP------------LVDTQDVLSE-----------RENSL 406 baker's yeast 1706421 363 --EHKLQLAsks-nieFGKTNTTNSEAKVKPIESFFQKMTKLDHNPKVANNIHSLRQAEDKLTMAI---------KRRKL 430 baker's yeast 7298467 372 --SENTHTPkkenpcaLFFKKVDFVGKTLNEEIEANQRLEQAKQTEAELFNMYSFKAKRRRSPSREdsv---dqeRTPPP 446 fruit fly 30685678 375 VCSLSKSEE-------IIELKRTADEAMIDPEAIVKKKMYSKQDSDLYKLLAQPNRDQVVTRPSNPsl-----ipDNNPF 442 thale cress 15220506 -------------------------------------------------------------------------------- thale cress 7487810 -------------------------------------------------------------------------------- thale cress 17553464 384 GLRYESKGStldkiskQKELEATQCGGAFKLDSPSVKRVKVASKTTPNDDEDDIVKQFMADIEKEKka------iKKRKN 457 Caenorhabditis elegans 19074876 355 RVDMHTHSPyfk-------------------------------------------------------------------- 366 Encephalitozoon cun... 18491018 369 SIWHRNYSPrpesgtvSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYslsftkktkKNSSE 448 human 18491020 369 SIWHRNYSPrpesgtvSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYslsftkktkKNSSE 448 human 1706728 364 NFFMKSIPP---------SKRPTKSTSLIDVTNVKVQRTHLANDISSEKQSIKSANEKAYVTPKSN---------SLKPG 425 fission yeast 2501673 363 --ERKLKARk------LFKVGLLGGES-----NSFNKKVEQP------------LVDTQDVLSE-----------RENSL 406 baker's yeast 1706421 363 --EHKLQLAsks-nieFGKTNTTNSEAKVKPIESFFQKMTKLDHNPKVANNIHSLRQAEDKLTMAI---------KRRKL 430 baker's yeast
18491016 449 GNKSlsFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNE---ESGAVVVPGTRSRFFCSSDS---TDCVSNKVSI 522 human 7298467 447 SPVHksRHNPFAKERTGEEANQRSPVVCENASLLRLLSPKKASPldgEAGVKKVDSLKRSIFAKEQVqirSRFFATQDEQ 526 fruit fly 30685678 443 KIRKtdEINLEIAEYGVQELADSFVTKSKAVDVASSSPNSHEHE---DQKECVTIDLSKLDAAGIKQdseKNRVKETFET 519 thale cress 15220506 -------------------------------------------------------------------------------- thale cress 7487810 -------------------------------------------------------------------------------- thale cress 17553464 458 APQVdyNADVLLKKYAEPPPEKRQKILEVIDDDFSEFFQEKVKEntkESVAEEKVENSNEELKPPPIlrkAVSTPDSARK 537 Caenorhabditis elegans 19074876 -------------------------------------------------------------------------------- Encephalitozoon cun... 18491018 449 GNKSlsFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNE---ESGAVVVPGTRSRFFCSSDS---TDCVSNKVSI 522 human 18491020 449 GNKSlsFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNE---ESGAVVVPGTRSRFFCSSDS---TDCVSNKVSI 522 human 1706728 426 FGKSlsDISNSATKNENVPFLPPRTGVSKYFKLQKNTEKEIDEQv-pSQSNNTTPTSAKSDSASPQNwfsSFSYQTPNSA 504 fission yeast 2501673 407 DNKN--ASSIYMTSPAAISGTVPSIF------------------------------------------------------ 430 baker's yeast 1706421 431 SNAN--VVQETLKDTRSKFFNKPSMTVVENFKEKGDSIQDFKEDt--NSQSLEEPVSESQLSTQIPSsfiTTNLEDDDNL 506 baker's yeast 7298467 447 SPVHksRHNPFAKERTGEEANQRSPVVCENASLLRLLSPKKASPldgEAGVKKVDSLKRSIFAKEQVqirSRFFATQDEQ 526 fruit fly 30685678 443 KIRKtdEINLEIAEYGVQELADSFVTKSKAVDVASSSPNSHEHE---DQKECVTIDLSKLDAAGIKQdseKNRVKETFET 519 thale cress 15220506 -------------------------------------------------------------------------------- thale cress 7487810 -------------------------------------------------------------------------------- thale cress 17553464 458 APQVdyNADVLLKKYAEPPPEKRQKILEVIDDDFSEFFQEKVKEntkESVAEEKVENSNEELKPPPIlrkAVSTPDSARK 537 Caenorhabditis elegans 19074876 -------------------------------------------------------------------------------- Encephalitozoon cun... 18491018 449 GNKSlsFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNE---ESGAVVVPGTRSRFFCSSDS---TDCVSNKVSI 522 human 18491020 449 GNKSlsFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNE---ESGAVVVPGTRSRFFCSSDS---TDCVSNKVSI 522 human 1706728 426 FGKSlsDISNSATKNENVPFLPPRTGVSKYFKLQKNTEKEIDEQv-pSQSNNTTPTSAKSDSASPQNwfsSFSYQTPNSA 504 fission yeast 2501673 407 DNKN--ASSIYMTSPAAISGTVPSIF------------------------------------------------------ 430 baker's yeast 1706421 431 SNAN--VVQETLKDTRSKFFNKPSMTVVENFKEKGDSIQDFKEDt--NSQSLEEPVSESQLSTQIPSsfiTTNLEDDDNL 506 baker's yeast
18491016 523 QPLDETAVTDKENNLHESEy--GDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVF 580 human 7298467 527 TRLQREHLRDTENDDMDEQk--LSSHSGHKKLRLVCKDIPGKNPIRQRCSSQISDGETDT 584 fruit fly 30685678 520 TEVDLAEVQDHVNMTTKRVr--GTKPRTENFKVKTSCKSSENNKTIIKKKHSILDFFQRL 577 thale cress 15220506 ------------------------------------------------------------ thale cress 7487810 ------------------------------------------------------------ thale cress 17553464 538 THKFQSPLLNHQNSAPPSLpdrKPAQTSKYFSKPTSENGVPKTKNPFRCPAFVKPTQKVE 597 Caenorhabditis elegans 19074876 ------------------------------------------------------------ Encephalitozoon cuniculi 18491018 523 QPLDETAVTDKENNLHESEy--GDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVF 580 human 18491020 523 QPLDETAVTDKENNLHESEy--GDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVF 580 human 1706728 505 SPPFSSLSHTLPISALAKIg--HDALNRKNHASLPSRRIVYKPPSSPSTPISMNPRPKGI 562 fission yeast 2501673 ------------------------------------------------------------ baker's yeast 1706421 507 SEEVSEVVSDIEEDRKNSE---GKTIGNEIYNTDDDGDGDTSEDYSETAESRVPTSSTTS 563 baker's yeast 7298467 527 TRLQREHLRDTENDDMDEQk--LSSHSGHKKLRLVCKDIPGKNPIRQRCSSQISDGETDT 584 fruit fly 30685678 520 TEVDLAEVQDHVNMTTKRVr--GTKPRTENFKVKTSCKSSENNKTIIKKKHSILDFFQRL 577 thale cress 15220506 ------------------------------------------------------------ thale cress 7487810 ------------------------------------------------------------ thale cress 17553464 538 THKFQSPLLNHQNSAPPSLpdrKPAQTSKYFSKPTSENGVPKTKNPFRCPAFVKPTQKVE 597 Caenorhabditis elegans 19074876 ------------------------------------------------------------ Encephalitozoon cuniculi 18491018 523 QPLDETAVTDKENNLHESEy--GDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVF 580 human 18491020 523 QPLDETAVTDKENNLHESEy--GDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVF 580 human 1706728 505 SPPFSSLSHTLPISALAKIg--HDALNRKNHASLPSRRIVYKPPSSPSTPISMNPRPKGI 562 fission yeast 2501673 ------------------------------------------------------------ baker's yeast 1706421 507 SEEVSEVVSDIEEDRKNSE---GKTIGNEIYNTDDDGDGDTSEDYSETAESRVPTSSTTS 563 baker's yeast
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",