7294498 120 VDLRLLPPIDSPSKIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGAL-------------------------DNIR 174 fruit fly 28381388 12 QNQNAANFLSNGKKIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQEG-------------------------QPIV 66 fruit fly 28381408 71 DDVTLLPPLTDPGKIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNALVGPQ-------------------------DNVI 125 fruit fly 15228286 2 ATSMIQRLFKQGTKIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENG-------------------------GTIE 56 thale cress 15234757 2 ATSMIQRMFKQGTKIVCVGRNYAAHAKELGNAVPKEPVIFLKPTSSYLENG-------------------------GTIE 56 thale cress 15234758 1 -------------------------------------------------------------------------------M 1 thale cress 466047 1 -MSSLAGFRNLATKIVCVGRNYKDHALELGNAIPKKPMLFVKTVNSFIVEG-------------------------EPIV 54 Caenorhabditis elegans 13637384 94 SEVTFLAPVTWPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPY-------------------------DEVV 148 human 13637384 94 SEVTFLAPVTWPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPY-------------------------DEVV 148 human 13654274 6 ASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEG-------------------------SPIL 60 human 7705608 94 SEVTFLAPVTRPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPY-------------------------DEVV 148 human 31077063 1 -------MLSRAGKVVCIGRNYAAHIRELNNPFPTKPFFFLKPTSAIVEPGh------------------------GNLI 49 fission yeast 1730800 1 ---MSYNYLKAARKIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLssslvkttrpanstfnglnedgtnpGPIF 77 baker's yeast 28381388 12 QNQNAANFLSNGKKIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQEG-------------------------QPIV 66 fruit fly 28381408 71 DDVTLLPPLTDPGKIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNALVGPQ-------------------------DNVI 125 fruit fly 15228286 2 ATSMIQRLFKQGTKIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENG-------------------------GTIE 56 thale cress 15234757 2 ATSMIQRMFKQGTKIVCVGRNYAAHAKELGNAVPKEPVIFLKPTSSYLENG-------------------------GTIE 56 thale cress 15234758 1 -------------------------------------------------------------------------------M 1 thale cress 466047 1 -MSSLAGFRNLATKIVCVGRNYKDHALELGNAIPKKPMLFVKTVNSFIVEG-------------------------EPIV 54 Caenorhabditis elegans 13637384 94 SEVTFLAPVTWPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPY-------------------------DEVV 148 human 13637384 94 SEVTFLAPVTWPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPY-------------------------DEVV 148 human 13654274 6 ASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEG-------------------------SPIL 60 human 7705608 94 SEVTFLAPVTRPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPY-------------------------DEVV 148 human 31077063 1 -------MLSRAGKVVCIGRNYAAHIRELNNPFPTKPFFFLKPTSAIVEPGh------------------------GNLI 49 fission yeast 1730800 1 ---MSYNYLKAARKIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLssslvkttrpanstfnglnedgtnpGPIF 77 baker's yeast
7294498 175 AHSSAKHIDYGCQLAVVMGKRCREVSPK---EALNHVFGFMVVQDIVARDWNVP--------LGGHSMDTFLPLGpTIVH 243 fruit fly 28381388 67 LPKVFTKVAYEVELGVVIGKPCKNVSKA---DAMSYVAGYCLALDLTAQCNLGParaaghpwTLGKGFDTSTPVS-QFIP 142 fruit fly 28381408 126 AHAASSKIDWEVELVCVIGKVARQVPKS---QAMDYVFGYSVAQDISARDWQKErng--gqfLMGKSMDTFLPLGpAVVH 200 fruit fly 15228286 57 IPHPLDSLHHEVELAVVIGQKARDVPER---LAMNYIGGYALALDMTARELQVSamasglpcTLAKGQDTFTPIS-SVLP 132 thale cress 15234757 57 IPHPLDSLHHEVELALVIGQKARDVPES---IAMDYIGGYAVALDMTARELQASakasglpwTVAKGQDTFTPIS-SVLP 132 thale cress 15234758 2 SEKGGKGLKSSLK-SKDGGKDGSSTKLK---KGTPPANYKILNVSSDQQPFQSSa-------AKCGKSDKPTKSSkNSLH 70 thale cress 466047 55 APPGCQNLHQEVELGVVISKKASRISKS---DAMDYIGGYTVALDMTARDFQDEakkagapwFLAKSFDGSCPIG-GFLP 130 Caenorhabditis elegans 13637384 149 LPPQSQEVDWEVELAVVIGKKGKHIKAT---DAMAHVAGFTVAHDVSARDWLTRrng--kqwLLGKTFDTFCPLGpALVT 223 human 13637384 149 LPPQSQEVDWEVELAVVIGKKGKHIKAT---DAMAHVAGFTVAHDVSARDWLTRrng--kqwLLGKTFDTFCPLGpALVT 223 human 13654274 61 MPAYTRNLHHELELGVVMGKRCRAVPEA---AAMDYVGGYALCLDMTARDVQDEckkkglpwTLAKSFTASCPVS-AFVP 136 human 7705608 149 LPPQSQEVDWEVELAVVIGKKGKHIKAT---DAMAHVGGFTVAHDVSARDWQMRrng--kqwLLGKTFDTFCPLGpALVT 223 human 31077063 50 IPPDVS-AHYEVELGLIMKDRLPARRPVssnSWLDSIGAYFVGIDMTARNIQNEakkkglpwSFAKGYDTFLPVG-PIIP 127 fission yeast 1730800 78 IPRGVK-VHHEIELALIVSKHLSNVTKMkpeEVYDSISGVALALDLTARNVQDEakkkglpwTISKGFDTFMPIS-AIVS 155 baker's yeast 28381388 67 LPKVFTKVAYEVELGVVIGKPCKNVSKA---DAMSYVAGYCLALDLTAQCNLGParaaghpwTLGKGFDTSTPVS-QFIP 142 fruit fly 28381408 126 AHAASSKIDWEVELVCVIGKVARQVPKS---QAMDYVFGYSVAQDISARDWQKErng--gqfLMGKSMDTFLPLGpAVVH 200 fruit fly 15228286 57 IPHPLDSLHHEVELAVVIGQKARDVPER---LAMNYIGGYALALDMTARELQVSamasglpcTLAKGQDTFTPIS-SVLP 132 thale cress 15234757 57 IPHPLDSLHHEVELALVIGQKARDVPES---IAMDYIGGYAVALDMTARELQASakasglpwTVAKGQDTFTPIS-SVLP 132 thale cress 15234758 2 SEKGGKGLKSSLK-SKDGGKDGSSTKLK---KGTPPANYKILNVSSDQQPFQSSa-------AKCGKSDKPTKSSkNSLH 70 thale cress 466047 55 APPGCQNLHQEVELGVVISKKASRISKS---DAMDYIGGYTVALDMTARDFQDEakkagapwFLAKSFDGSCPIG-GFLP 130 Caenorhabditis elegans 13637384 149 LPPQSQEVDWEVELAVVIGKKGKHIKAT---DAMAHVAGFTVAHDVSARDWLTRrng--kqwLLGKTFDTFCPLGpALVT 223 human 13637384 149 LPPQSQEVDWEVELAVVIGKKGKHIKAT---DAMAHVAGFTVAHDVSARDWLTRrng--kqwLLGKTFDTFCPLGpALVT 223 human 13654274 61 MPAYTRNLHHELELGVVMGKRCRAVPEA---AAMDYVGGYALCLDMTARDVQDEckkkglpwTLAKSFTASCPVS-AFVP 136 human 7705608 149 LPPQSQEVDWEVELAVVIGKKGKHIKAT---DAMAHVGGFTVAHDVSARDWQMRrng--kqwLLGKTFDTFCPLGpALVT 223 human 31077063 50 IPPDVS-AHYEVELGLIMKDRLPARRPVssnSWLDSIGAYFVGIDMTARNIQNEakkkglpwSFAKGYDTFLPVG-PIIP 127 fission yeast 1730800 78 IPRGVK-VHHEIELALIVSKHLSNVTKMkpeEVYDSISGVALALDLTARNVQDEakkkglpwTISKGFDTFMPIS-AIVS 155 baker's yeast
7294498 244 RCHVPDLNN-----LWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCP-GDIILTGTPAGSGAFRhpscflkPGD 317 fruit fly 28381388 143 IEKVTDPHN-----LPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEA-NDLILTGTPNGADAFK-------AGD 209 fruit fly 28381408 201 KSLVPDVYN-----LNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQTITLLP-GDIIVTGTPKGVGMHRtppeflqPGD 274 fruit fly 15228286 133 KAMVLDPNN-----LELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTLFK-GDVILTGTPEGIGPVK-------IGQ 199 thale cress 15234757 133 KAMVRDPDN-----LELWLKVDGETRQKGLTKDMIFKVPYLISYISSIMTLY--GDVILTGTPEGVGPVK-------IGQ 198 thale cress 15234758 71 SFELKDLMTe----HWLMLRVVFTT-QTLNLSEKSLSILLAVLRLHWIRFVSHsMCVIANASSESVDEVLaf---ipSLK 142 thale cress 466047 131 VSDIPNPHD-----VELFCKINGKDQQRCRTDVMIFDIPTLLEYTTQFFTLEV-GDVVLTGTPAGVTKIN-------SGD 197 Caenorhabditis elegans 13637384 224 KDSVADPHN-----LKICCRVNGEVVQSSNTNQMVFKTEDLIAWVSQFVTFYP-GDVILTGTPPGVGVFRkppvflkKGD 297 human 13637384 224 KDSVADPHN-----LKICCRVNGEVVQSSNTNQMVFKTEDLIAWVSQFVTFYP-GDVILTGTPPGVGVFRkppvflkKGD 297 human 13654274 137 KEKIPDPHK-----LKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEE-GDIILTGTPKGVGPVK-------END 203 human 7705608 224 KDSVADPHN-----LKICCRVNGEVVQSGNTNQMVFKTEDLIAWVSQFVTFYP-GDVILTGTPPGVGVFRkppvflkKGD 297 human 31077063 128 KHLIPDPHN-----VILELSLNGKVVQKDSTSLMLNKIPKIFSSITEAMSLNP-GDLVLTGTPKGVGPVV-------PGD 194 fission yeast 1730800 156 REKFSSYKSnlqdiFRVKCSVNGQLRQDGGTNLMLHPLHKILQHISTMISLEP-GDIILTGTPAGVGELK-------PGD 227 baker's yeast 28381388 143 IEKVTDPHN-----LPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEA-NDLILTGTPNGADAFK-------AGD 209 fruit fly 28381408 201 KSLVPDVYN-----LNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQTITLLP-GDIIVTGTPKGVGMHRtppeflqPGD 274 fruit fly 15228286 133 KAMVLDPNN-----LELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTLFK-GDVILTGTPEGIGPVK-------IGQ 199 thale cress 15234757 133 KAMVRDPDN-----LELWLKVDGETRQKGLTKDMIFKVPYLISYISSIMTLY--GDVILTGTPEGVGPVK-------IGQ 198 thale cress 15234758 71 SFELKDLMTe----HWLMLRVVFTT-QTLNLSEKSLSILLAVLRLHWIRFVSHsMCVIANASSESVDEVLaf---ipSLK 142 thale cress 466047 131 VSDIPNPHD-----VELFCKINGKDQQRCRTDVMIFDIPTLLEYTTQFFTLEV-GDVVLTGTPAGVTKIN-------SGD 197 Caenorhabditis elegans 13637384 224 KDSVADPHN-----LKICCRVNGEVVQSSNTNQMVFKTEDLIAWVSQFVTFYP-GDVILTGTPPGVGVFRkppvflkKGD 297 human 13637384 224 KDSVADPHN-----LKICCRVNGEVVQSSNTNQMVFKTEDLIAWVSQFVTFYP-GDVILTGTPPGVGVFRkppvflkKGD 297 human 13654274 137 KEKIPDPHK-----LKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEE-GDIILTGTPKGVGPVK-------END 203 human 7705608 224 KDSVADPHN-----LKICCRVNGEVVQSGNTNQMVFKTEDLIAWVSQFVTFYP-GDVILTGTPPGVGVFRkppvflkKGD 297 human 31077063 128 KHLIPDPHN-----VILELSLNGKVVQKDSTSLMLNKIPKIFSSITEAMSLNP-GDLVLTGTPKGVGPVV-------PGD 194 fission yeast 1730800 156 REKFSSYKSnlqdiFRVKCSVNGQLRQDGGTNLMLHPLHKILQHISTMISLEP-GDIILTGTPAGVGELK-------PGD 227 baker's yeast
7294498 318 LIESEIQN-----LGKMCNKVVNS 336 fruit fly 28381388 210 VIQCGMAD-----LAKLTFQVEAE 228 fruit fly 28381408 275 VVQSEIVG-----LGKLCNKIVAP 293 fruit fly 15228286 200 KITAGITG-----LSEVQFDVGRR 218 thale cress 15234757 199 KITAGITG-----LSEVQFDVERR 217 thale cress 15234758 143 VRPLELPEs----DSDVCVVIL-- 160 thale cress 466047 198 VIEFGLTD-----KLNSKFNVQ-- 214 Caenorhabditis elegans 13637384 298 EVQCEIEE-----LGVIINKVV-- 314 human 13637384 298 EVQCEIEE-----LGVIINKVV-- 314 human 13654274 204 EIEAGIHG-----LVSMTFKVEKP 222 human 7705608 298 EVQCEIEE-----LGVIINKVV-- 314 human 31077063 195 ILSARLLTaqeqeIIPSKFEIKAE 218 fission yeast 1730800 228 RVHCELLQnn-dnIVDMNFECENR 250 baker's yeast 28381388 210 VIQCGMAD-----LAKLTFQVEAE 228 fruit fly 28381408 275 VVQSEIVG-----LGKLCNKIVAP 293 fruit fly 15228286 200 KITAGITG-----LSEVQFDVGRR 218 thale cress 15234757 199 KITAGITG-----LSEVQFDVERR 217 thale cress 15234758 143 VRPLELPEs----DSDVCVVIL-- 160 thale cress 466047 198 VIEFGLTD-----KLNSKFNVQ-- 214 Caenorhabditis elegans 13637384 298 EVQCEIEE-----LGVIINKVV-- 314 human 13637384 298 EVQCEIEE-----LGVIINKVV-- 314 human 13654274 204 EIEAGIHG-----LVSMTFKVEKP 222 human 7705608 298 EVQCEIEE-----LGVIINKVV-- 314 human 31077063 195 ILSARLLTaqeqeIIPSKFEIKAE 218 fission yeast 1730800 228 RVHCELLQnn-dnIVDMNFECENR 250 baker's yeast
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",