19114729 30 HELRKNRTFMLDLGVSILKKFLIDSRDYKVEVVQDFCSRSLTDEFKFkftSQPIDSKSESDsa-syIRNYLGPEGIKQFG 108 fission yeast 17540028 33 PLPEGFTIS-KWDRAVMHVVEPALRVAYYYPS-RMFTKPSNMVQWTR---GALNTLSKTLGll--vNTHGQVDIKWHKWN 105 Caenorhabditis elegans 17565640 29 PLPPGLCEKSTVDRVVIHLFEPILRAFYYYPANYIFTTPANQIWWTR---YSLGLLAKTMGpvtlfERH-LVRVTDATWN 104 Caenorhabditis elegans 29727802 32 DIPATLQHP-AKLRFLHCIFLYLVTLGNIFEKLGICSMPKFIRFLH-----DSVRIKKDPE----------LVVTDLRFG 95 human 29728555 54 PLPGSVSDP-WKLMLLDATFRGAQQVSNLIHYLGLSHHLLALNFIIVs--FGKKSAWSSAQ----------VKVTDTDFD 120 human 30147098 1 ---------------------------MIFEKLRICSMPQFFCFMQ-----DLPPLKYDPD----------VVVTDFRFG 38 human 20477603 1 ---------------------MVTNLALLVELLGINHFMNTATFFVS---FQEVPPTSDEN----------VTMIETTFS 46 human 29730106 1 -MPDNIEES-WKIMALDAIAKTCTFTAMCFENMRIMRYEEFISMIFR---LDYTQPLSDEY----------ITVTDTTFV 65 human 1703031 22 PLPDNVEEP-WRMMWINAHLKTIQNLATFVELHGSSIFMDSFKVVGS---FDEVPPTSDEN----------VTVTETKFN 87 human 19114910 1 -MAELEFTDEKFTKVDPELKEILKKHPAGTENITNIWQMRAMDEECRkqlAETILPLPDDVs------VTDILIPTRDGT 73 fission yeast
19114729 109 GSNWWLYRKSPLKSWwierrhhirhnlKCDKVIFYVHGGAHYLSTVRTNAYHIQRHT-----AALGARTFAPDLRLAPQF 183 fission yeast 17540028 106 ETPVKVYRPTNNKT-------------STDGAVLFIHGGGFALG--NVDMYDSLVKRm---aYEMKTLFISIEYRLSPET 167 Caenorhabditis elegans 17565640 105 GVHVRTYEPRLVEN-------------STDGAVIFIHGGGFAIGSVAINVQNSIFFFnflkvFSMNTFVVSIDYRLSPET 171 Caenorhabditis elegans 29727802 96 TIPVRLFQPKAASS-------------RPRRGIIFYHGGATVFGS--LDCYHGLCNYl---aRETESVLLMIGYRKLPDH 157 human 29728555 121 GVEVRVFEGPPKPEE------------PLKRSVVYIHGGGWALASAKIRYYDELCTAm---aEELNAVIVSIEYRLVPKV 185 human 30147098 39 TIPVKLYQSKASTC-------------TLKPGIVYYHGGGGVMGS--LKTHHGICSRl---cKESDSVVLAVGYRKLPKH 100 human 20477603 47 NIPVRVYMPTLKSE-------------ILRTGLVYIHGGGWCMGDAGMCSILKVLVYh---iTYILLKC----------- 99 human 29730106 66 DIPVRLYLPKRKSE-------------TRRRAVIYFHGGGFCFGSSKQRAFDFLNRWt---aNTLDAVVVGVDYRLAPQH 129 human 1703031 88 NILVRVYVPKRKSE-------------ALRRGLFYIHGGGWCVGSAALSGYDLLSRWt---aDRLDAVVVSTNYRLAPKY 151 human 19114910 74 EIDGRVFTPVSVPA-------------DYRSLMVFYHSSGWCMRG--VRDDDSLFKIl---tPKFGCVCVSVDYRLAPES 135 fission yeast
19114729 184 PFPCSLHDVLSSYLYLLKSTkpeniifmgdssgaglivaSLVLIRDSKLplpAGVVYDSPWVDLTHSLPSVVADDAad-- 261 fission yeast 17540028 168 VFPGGILDCEAAIDHFFDFG-------------------AVQFGVNTSK---VVIMGDSAGGNLATVIAQRra------- 218 Caenorhabditis elegans 17565640 172 VFPENLLDCEKAIDYFLENS-------------------LEKFKIDPKK---VILVGDSAGGNLATAIAQRra------- 222 Caenorhabditis elegans 29727802 158 HSPALFQDCMNASIHFLKA--------------------LETYGVDPSR---VVVCGESVGGAAVAAITQAlv------- 207 human 29728555 186 YFPEQIHDVVRATKYFLKPEv------------------LQKYMVDPGR---ICISGDSAGGNLAAALGQQFTQDAs--- 241 human 30147098 101 KFPVPVRDCLVATIHFLKS--------------------LDAYGVDPAR---VVVCGDSFGGAIAAVVCQQlv------- 150 human 20477603 -------------------------------------------------------------------------------- human 29730106 130 HFPAQFEDGLAAVKFFLLEKi------------------LTKYGVDPTR---ICIAGDSSGGNLATAVTQQNITIYfqvq 188 human 1703031 152 HFPIQFEDVYNALRWFLRKKv------------------LAKYGVNPER---IGISGDSAGGNLAAAVTQQlld------ 204 human 19114910 136 KFPVAHNDAIDSFKWVASN--------------------IEKLGANPKRg--FFLGGASAGGNFVSVLSHIARDEK---- 189 fission yeast
19114729 262 -yiPSEGFHHRASRYWPITNLDSFSTISEKELLNYSkkqeltnfiensirkk--------iqtiknlipvlqemdKEHAR 332 fission yeast 17540028 219 -arNSFPKLAGQVLIYPLLQMADMQTVSYRYFHSRLrgyalvdpesvayyymfyagidmdekaylvpsvisnghvANHLQ 297 Caenorhabditis elegans 17565640 223 -ekGAEPKLLAQVLLYPLLQLVDLQMTSYRYFHKRLtgiafvdpasvafyymlyagiplekakelvpivltnghvKPDYR 301 Caenorhabditis elegans 29727802 208 -grSDLPRIRAQVLIYPVVQAFCLQLPSFQQNQNvpllsrkfmvtslcnyl--------aidlswrdailngtcvPPDVW 278 human 29728555 242 ----LKNKLKLQALIYPVLQALDFNTPSYQQNVNTPilpryvmvkywvdyfkgn----ydfvqamivnnhtsldvEEAAA 313 human 30147098 151 -drPDLPRIRAQILIYAILQALDLQTPSFQQRKNiplltwsficycffqnl--------dfssswqevimkgahlPAEVW 221 human 20477603 -------------------------------------------------------------------------------- human 29730106 189 ndaEIKHKIKMQVLLYPGLQITDSYLPSHRENEHgivltrdvaiklvslyf--------tkdealpwamrrnqhmPLESR 260 human 1703031 205 -dpDVKIKLKIQSLIYPALQPLDVDLPSYQENSNflflskslmvrfwseyf--------ttdrslekamlsrqhvPVESS 275 human 19114910 190 ----IKPELTGLWHMVPTLIHPADLDEETMAQFRSYk--------------------------------------ETIHA 227 fission yeast
19114729 333 IDFDNVDS-RLDPNILTtfpfqvq-------fytsnaNLKHPLISPIFTenlgglppSLVLGGSGERLRDEIVYIAHkmn 404 fission yeast 17540028 298 SEASEIMSyKSVIEMKHnyknhsiterwevsqsyeaqDLMEPFLTNPDFs------pLMRKD--LSNLPPTMVITCE--- 366 Caenorhabditis elegans 17565640 302 EKIDKLLTyRTTIESTHtynttkipkrweivenseaqNLLEKVIFDPNFs------pIMREN--LENLPKSLIVTCE--- 370 Caenorhabditis elegans 29727802 279 RKYEKWLSpDNIPKKFKnrgyqpws----pgpfneaaYLEAKHMLDVENs------pLIADDEVIAQLPEAFLVSCE--- 345 human 29728555 314 VRARLNWT-SLLPASFTknykpvvq-----ttgnariVQELPQLLDARSa------pLIADQAVLQLLPKTYILTCE--- 378 human 30147098 222 EKYRKWLGpENIPERFKergyqlkp----hepmneaaYLEVSVVLDVMCs------pLIAEDDIVSQLPETCIVSCE--- 288 human 20477603 -------------------------------------------------------------------------------- human 29730106 261 HLFKFVNWsILLPEKYRkdyvyte-------pilgglSYSLPGLTDSRAl------pLLANDSQLQNLPLTYILTCQ--- 324 human 1703031 276 HLFKFINWsSLLPERFIkghvynnp-----nygsselAKKYPGFLDVRAa------pLLADDNKLRGLPLTYVITCQ--- 341 human 19114910 228 PVITPKIMdIFFENYQP--------------------TPKSPLVNPLY------------YPTGHKDLPPSFFQCCG--- 272 fission yeast
19114729 405 TDVYNgkrtkvrlemyDDCCHVVTALpfvKEAGIMVRraanFAYWCLKQHDSSFVSPNkhldGNPSHANEDMVRLRISRN 484 fission yeast 17540028 367 FDILR-----------DEGLIYGERL---KVSGVPTT----TIHYENGFHAMLNFHSe----LDEASKSVDDIEQWTLNA 424 Caenorhabditis elegans 17565640 371 YDVLR-----------DEGLIYSERL---MASGVPTK----LINYKNGYHAMLNMHNe----ITEASTCLDDVMHWILEQ 428 Caenorhabditis elegans 29727802 346 NDILR-----------DDSLLYKKRL---EDQGVRVT----WYHLYDGFHGSIIFFDKkalsFPCSLKIVNAVVSYIKGI 407 human 29728555 379 HDVLR-----------DDGIMYAKRL---ESAGVEVT----LDHFEDGFHGCMIFTSWpt-nFSVGIRTRNSYIKWLDQN 439 human 30147098 289 YDALR-----------DNSLLYKKRL---EDLGVPVT----WHHMEDGFHGVLRTIDMsflhFPCSMRILSALVQFVKGL 350 human 20477603 -------------------------------------------------------------------------------- human 29730106 325 HDLLR-----------DDGLMYVTRL---RNVGVQVV----HEHIEDGIHGALSFMTSpf-yLRLGLRIRDMYVSWLDKN 385 human 1703031 342 YDLLR-----------DDGLMYVTRL---RNTGVQVT----HNHVEDGFHGAFSFLG-----LKISHRLINQYIEWLKEN 398 human 19114910 273 WDPLR-----------DEGIAYEKAL---KAAGNETR----LIVYEGVPHCFWVYYPMlslrKKYFEDAIDGFTWLLSHV 334 fission yeast
19114729 485 G 485 fission yeast 17540028 425 I 425 Caenorhabditis elegans 17565640 429 F 429 Caenorhabditis elegans 29727802 - human 29728555 440 L 440 human 30147098 - human 20477603 - human 29730106 386 L 386 human 1703031 399 L 399 human 19114910 335 K 335 fission yeast