15218352 534 KMtTtSKTSLQEEYVI-DAVDHRGFSARRS---------ITGRWRAAWFIIGVEVAERFANYGI-------------GSN 590 thale cress 7290444 63 NKlGyNEETATVLFHTfTMLVYIFPLIGALiadgwlgkyKTILYLSLVYSLGAMVVSFGAV-PLsg----------mpTK 131 fruit fly 2811011 44 TEhEfSPSKATFIYHLfTCIAYLTPLIGSImadsvfgrfKVILYGSSIYVVGHVLLSLGAVPFLsy----------pIRS 113 Caenorhabditis el... 17569141 75 NVlKfTDSQSTIFFNGfTVLCYTTPLLGSIvadgyigkfWTIFSVSILYAIGQVVLALASTKNFqs----------sVHP 144 Caenorhabditis el... 17543500 -------------------------------------------------------------------------------- Caenorhabditis el... 21264414 61 NIlNfSQSFSTVLFHAfTVICYSSPLLGSIladgyigkfWTIFFISIFYACGQILLAFSSIAPSgs----------sHHP 130 Caenorhabditis el... 19074905 1 --------------------------------------mTIMNGTTLFLIICNEFCERFCFYGL--------------KS 28 Encephalitozoon c... 2833272 73 YFlHwNEDTSTSIYHAfSSLCYFTPILGAAiadswlgkfKTIIYLSLVYVLGHVIKSLGALPILgg---------qvVHT 143 human 1172435 43 NFiSwDDNLSTAIYHTfVALCYLTPILGALiadswlgkfKTIVSLSIVYTIGQAVTSVSSINDLtdhnhdgtpdslpVHV 122 human 19113209 1 -------------------MSSIEEQITKsds-----dfIISEDQSYLSKEKKADGSATIN-----------------TA 39 fission yeast
15218352 591 LISYLTGPLGQST-AVAAANVNAWSGISTILPLLGAFVADAFLGRYITIIIASFIYVLG--------------------L 649 thale cress 7290444 132 AVTVVGLLLIAIGtGGIKPCVSAFGGDQFSLPAQSFQLAKFFSLFYFAINAGSLISTTFtpilradvhc-fgdqdcfslA 210 fruit fly 2811011 114 SLDFSGLFVIAFAtGCIKPCVSAFAADQFTE-DQKDLRSQFFSFFYFAINGGSLFAIIItpilrgrvqc-fgnahcfplA 191 Caenorhabditis el... 17569141 145 WMDLSGLLIIAFGtGGIKPCVSAFGGDQFEL-GQERMLSLFFSMFYFSINAGSMISTFIspifrsqpc--lgqdscypmA 221 Caenorhabditis el... 17543500 -------------------------------------------------------------------------------- Caenorhabditis el... 21264414 131 LLDLLGLLIVGLGtGGIKPCVSAFGGDQFPA-HYTRMISLFFSMFYFSINAGSLISMWLtpyfrsmsc--fghdscyplA 207 Caenorhabditis el... 19074905 29 LLFSFTRSEYGFTiKESTVNLHFFISMSYLFTLFGGLLSDMFLGRYSTIVLLSSLYLTG--------------------T 88 Encephalitozoon c... 2833272 144 VLSLIGLSLIALGtGGIKPCVAAFGGDQFEE-KHAEERTRYFSVFYLSINAGSLISTFItpmlrgdvq--cfgedcyalA 220 human 1172435 123 VLSLIGLALIALGtGGIKPCVSAFGGDQFEE-GQEKQRNRFFSIFYLAINAGSLLSTIItpmlrvqqcgihskqacyplA 201 human 19113209 40 DEQSSTDELQKSMsTGVLVNGDLYPSPTEEELATLPRVCGTIPWKAFIIIIVELCERFAyygltv--------pfqnymQ 111 fission yeast
15218352 650 AFLTLSAFLIPN---------------NTEVTSSPSSFLNALFFFSLYLVAIGQSGHKPCVQAFGADQFD---------- 704 thale cress 7290444 211 FGVPAILMIFSViifmagkrlyrcqppAGNMIFGVSRCIADAFKGWQKRR--HSEP-MESFLDYAKPTVGsrmv------ 281 fruit fly 2811011 192 FGVPGVLMLLALilflmg---wsmykkHPPSKENVGSKVVAVIYTSLRKMVGGASRDKPVTHWLDHAAPEhsqkm----- 263 Caenorhabditis el... 17569141 222 FGIPAILMIVATlvfmggsfwykknppKDNVFGEVSRLMFRAVGNKMKSGSTPKEHWLLHYLTTHDCALDakclelqaek 301 Caenorhabditis el... 17543500 -------------------------------------------------------------------------------- Caenorhabditis el... 21264414 208 FGIPAILMIVATlvfmag---sfwykkVPPKENIIFKVIGTITTALRKKASSSSTHQRSHWLEYSLDGHDcalstecknl 284 Caenorhabditis el... 19074905 89 SLLTYCSIVS----------------------GSPG-----LMVGSLLMIAVGTGGIKPCVAAFGGDQFG---------- 131 Encephalitozoon c... 2833272 221 FGVPGLLMVIALvvfamgskiynkpppEGNIVAQVFKCIWFAISNRFKNRS-GDIPKRHDWLDWAAEKYPkqli------ 293 human 1172435 202 FGVPAALMAVALivfvlgsgmykkfkpQGNIMGKVAKCIGFAIKNRFRHRS-KAFPKREHWLDWAKEKYDerli------ 274 human 19113209 112 FGPKDATPGALNlgesgadglsnfftfWCYVTPVGAALIADQFLGRYNTIVCSAVIYFIGILILTCTAIPsvid------ 185 fission yeast
15218352 705 ----------------EKNPQENSDRSSFFNWWYLSMCAGIGLAILVVVYIQ------ENVSWALGFGIPCVFMVISLVL 762 thale cress 7290444 282 ------------qetkCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMDG-------NVLGFQIKPDQMQVVNPLLILG 342 fruit fly 2811011 264 -----------idstrGLLNVAVIFCPLIFFWALFDQQGSTWVLQARRLDG-------RVGHFSILPEQIHAINPVCVLI 325 Caenorhabditis el... 17569141 302 rnknlcqkkkfiddvrSLLRVLVMFLPVPMFWALYDQQGSVWLIQAIQMDCR------LSDTLLLLPDQMQTLNAVLILL 375 Caenorhabditis el... 17543500 -------------------------------------------------------------------------------- Caenorhabditis el... 21264414 285 hg--ncaqrryiedikRLFRVIVMMIPVPMFWALYDQQGSTWVLQAVGMDA-------KVFGFEILPDQMGVLNAFLILF 355 Caenorhabditis el... 19074905 132 -------------------PDDAQDLRRFFDFFYFAINIGSMVSMVLTPTMSsvgclgKQSCYPLAFGTSSTLLGASILL 192 Encephalitozoon c... 2833272 294 ------------mdvkALTRVLFLYIPLPMFWALLDQQGSRWTLQAIRMNR-------NLGFFVLQPDQMQVLNPLLVLI 354 human 1172435 275 ------------sqikMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSG-------KIGALEIQPDQMQTVNAILIVI 335 human 19113209 186 -------------agkSMGGFVVSLIIIGLGTGGIKSNVSPLMAEQLPKIPP------YVKTKKNGSKVIVDPVVTTSRA 246 fission yeast
15218352 763 FVLGRKSYRFSKt--rQEEEt-nPFTRIGRVFFVAFKNQRLNSSDL----------CKv------------ELIEANRSQ 817 thale cress 7290444 343 FLPLFDYIIYPAlarcGIRRp-lQKLTLGLLLAALGFFLSAGLEMKmeqaayratpIEpdmthlriyngmpCRYEISSAV 421 fruit fly 2811011 326 LVPIFEGWVYPAlrkiTRVTp-lRKMAVGGLLTAFSFAIAGVLQLK----------VNetmefp---pslgrIYLQRVGN 391 Caenorhabditis el... 17569141 376 FIPLFQVIIYPVaakcVRLTp-lRKMVTGGLLASLAFLITGFVQLQvnttl-ptlpEEgeasis-fwnqfeTDCTITVMS 452 Caenorhabditis el... 17543500 -------------------------------------------------------------------------------- Caenorhabditis el... 21264414 356 FIPIFQSIVYPTieklGFQMtmlRKMAGGGILTAVSFFVCGIVQLFvnptlpyipmANeahlti---intipSCDFNVLI 432 Caenorhabditis el... 19074905 193 FIIGKRFYVIKP----VRKE---QFSRTFHSLVQNLKELFRRQSRD-----------------------------SERKT 236 Encephalitozoon c... 2833272 355 FIPLFDFVIYRLvskcGINFsslRKMAVGMILACLAFAVAARVEIKinema-paqpGPqevflq---vlnlaDDEVKVTV 430 human 1172435 336 MVPIFDAVLYPLiakcGFNFtslKKMAVGMVLASMAFVVAAIVQVEidktl-pvfpKGnevqik---vlnigNNTMNISL 411 human 19113209 247 YMIFYWSINVGSlsvlATTSlesTKGFVYAYLLPLCVFVIPLIILAvskrfykhtpPSgsif-----vrvgQVFF--LAA 319 fission yeast
15218352 818 ES---------------PEELSFLNKALLVPN---------DSDEG-EVACKSRDVEDATALVRLIPVWLTTLAYAIPFA 872 thale cress 7290444 422 VQtp-----------rvIEPLNVWEDLSLQMTeskeytfnaQP----VSGECPSIIDKLRLQPGKSVSYFLAQDKLVEFA 486 fruit fly 2811011 392 ESl--------------ISDFRYKSDGRLIGDgmlp-kgrtELDAGiYTFNTGLKNESQEIDISTPNKGYVMAVFRLKDA 456 Caenorhabditis el... 17569141 453 GIhkrvlphdkylhedkKNKSGIYNLFTTKSPakgngdwtlTYDLS-YDGACGDTSKLEKTVKVTAKSKKIIYVGVGSFG 531 Caenorhabditis el... 17543500 -------------------------------------------------------------------------------- Caenorhabditis el... 21264414 433 DS---------------REPFDLLRKSGIAPDdsvrkpisfTGDDFfQPNITFDNLAPNCPKFTAEPMLAPATSYVLTLS 497 Caenorhabditis el... 19074905 237 QG-----------------TLKTVSEAA----------------------CISHEEDDKEKTLKILRILGPAAFFWMLSD 277 Encephalitozoon c... 2833272 431 VGnen----------nsLLIESIKSFQKTPHYsklhlktksQDFHFhLKYHNLSLYTEHSVQEKNWYSLVIREDGNSISS 500 human 1172435 412 PGem-----------vtLGPMSQTNAFMTFDVnkltrinisS-----PGSP-VTAVTDDFKQGQRHTLLVWAPN----HY 470 human 19113209 320 QN---------------KFN-----LEKTKPSctttvgrvtL-----KDQWDDLFIDELKRALRACKTFLFYPIYWVCYG 374 fission yeast
15218352 873 QYMTFFTKQGVTMERTIFPG------------------------------------------------------------ 892 thale cress 7290444 487 DGLQMAATDTGRTSVrallntp---------------------------------------------------------- 508 fruit fly 2811011 457 VEVVKFDYKVEKTDNGATRVfvv--------------------------------------------------------- 479 Caenorhabditis el... 17569141 532 YYQNTANTDKPTDGTGEFSMgivtvfnssyggnfamcrqntsdfdvnhpcnprhpadfyfwetdynshtddrdqnatitg 611 Caenorhabditis el... 17543500 -------------------------------------------------------------------------------- Caenorhabditis el... 21264414 498 PNGWAYNAVRPEKPKSGKGElsmglnlivpcdkipsnvtweqcngtegy-----------sgaialckvesdvitdnnnv 566 Caenorhabditis el... 19074905 278 QQSSSWVEQGTKMETHQSILgy---------------------------------------------------------- 299 Encephalitozoon c... 2833272 501 MMVKD-TESRTTNGMttvrfvn---------------------------------------------------------- 521 human 1172435 471 QVVKDGLNQKPEKGEngirfvn---------------------------------------------------------- 492 human 19113209 375 QMTNNLISQAGQMQTgnvs------------------------------------------------------------- 393 fission yeast
15218352 893 ---------VEIPPASLQVLISISIVLFVPIYDRVLVPIGRSITKDP----CGITTLKRIGTGMVLATLTMVVAALVESK 959 thale cress 7290444 509 --dgegpvlLSTESATSQEPPLTLDKGNVPQLHRITPGFARVDINGK-----KVASFEAKEGRLYSILVTGSARDGYQHN 581 fruit fly 2811011 480 ------tarEDADTLVYAINKKGKILSSCELKSGSYVDVIPGIISDPnvrlYWGPKNSCSGVDCPNTVTLNAQMGAVHVL 553 Caenorhabditis el... 17569141 612 slssqpavtYKQKSVKPGYWQLYYLLNTPKDVDRQTYNKTATLVAPT-----NYGFHRVKQGGVFIYALT-GTYENPKIH 685 Caenorhabditis el... 17543500 1 ----------------------------------MVSTCCEPVATPT-----VLDNIIRQYQGCAAVGCR-RQPTAEKLA 40 Caenorhabditis el... 21264414 567 cdptakgkfYVLSNANPLDVHDFSKKSTVTAFGRTYSPIEMKPGTYRl---FYTDDSRTHFTPLNLPPVQQDHMGGQYLI 643 Caenorhabditis el... 19074905 300 --------gMDILPSQMQAFNAVFILLFIPLFSKMIYPLMG-LAG------VFSSPEEKMGFGIALASLSFFCSGYLEYR 364 Encephalitozoon c... 2833272 522 --tlhkdvnISLSTDTSLNVGEDYGVSAYRTVQRGEYPAVHCRTEDKn---FSLNLGLLDFGAAYLFVITNNTNQGLQAW 596 human 1172435 493 --tfnelitITMSGKVYANISS-YNASTYQFFPSGIKGFTISSTEIPpqcqPNFNTFYLEFGSAYTYIVQRKNDSCPEVK 569 human 19113209 394 -----ndlfQAFDSIALIIFIPICDNIIYPLLRKYNIPFKPILRITLg---FMFATASMIYAAVLQAKIY--QRGPCYAN 463 fission yeast
15218352 960 RLETAKEygl-----idQPKTTLPMSIWWLFPQYMLLGLADVHTLVGMQEFFYSQVPTELRSLGLAIYLSAMGVGSLLSS 1034 thale cress 7290444 582 VIEVVAL---------------STVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPSMKSVLQACWLLSVAIGNMLVV 646 fruit fly 2811011 554 HIHPSTTegd-----fnLLVRPNSVSILWSLPQYIIITLGEVLLSVTGLEFAYSQAAPNMKSVLTAMWLLTVFAGNLIDM 628 Caenorhabditis el... 17569141 686 ELQIVQS---------------NSVSILWQIPQIVVITAAEILFSITGYEFAYSQSAPSMKALVQALWLLTTAAGDSIIV 750 Caenorhabditis el... 17543500 41 SFRLSAS---------------ADSRVIGFFGCFEKFYKKKFSITLS-KICSDQKSAPSMKALVQALWLLTVAGGDAIIV 104 Caenorhabditis el... 21264414 644 TVSTRSKndsevlatteSLVSYNRVSILWQIPQYVILTAGEVLFSITGLEFAYTEASPQLKSVVQALWLFTTAIGDLIVV 723 Caenorhabditis el... 19074905 365 IGLPAPAg--------------QRLSIMWQLPQYVLMTAGEIMLNVTGMEYMYTEAPEPMKSLVSSMWLLTVTAGNLLVM 430 Encephalitozoon c... 2833272 597 KIEDIPA---------------NKMSIRWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIVL 661 human 1172435 570 VFEDISA---------------NTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVL 634 human 19113209 464 FTDTCVS---------------NDISVWIQIPAYVLIAFSEIFASITGLEFAFTKAPPSMKSIITALFLFTNAFGAILSI 528 fission yeast
15218352 1035 LLIYLIDLATGGda--gN-SWFN-SNLNRAHLDYFYWLLAVVSAVGFFTFLFISKSYIYRRVDVV 1095 thale cress 7290444 647 VIAEFKFTSs------qSgEFTLfASLMLVDMMIFLWLARSYQYKDQREDFEDD------DDATi 699 fruit fly 2811011 629 MISGTRLIPHP------AlEFFFySTLMVIVMGVFILLAMQYTYVEDNDDEITITESEKKDVIAL 687 Caenorhabditis elegans 17569141 751 VITILNLFEn------mAvEFFVyAAAMFVVIAIFALLSIFYYTYNYYTTDEEDGEIGVDDEEEI 809 Caenorhabditis elegans 17543500 105 LITILNLFYn------mAvQFFVyAAAMFVVIAIFALLSIFYYTYNCYTTDEDD----E--NEGI 157 Caenorhabditis elegans 21264414 724 VIFMLNIFSDVAvqmfvFgGIMLfVIFVFILLAVFYYEYADYSNESEVLTEKMIVDDDHTRI--- 785 Caenorhabditis elegans 19074905 431 VLT-----------------FLDpVALFSSRAHDMWSFVAYGTAGLLASRCMFQASKAAKRNRK- 477 Encephalitozoon cuniculi 2833272 662 VVA---QFSGlv----qWaEFILfSCLLLVICLIFSIMG--YYYV-PVKTEDMRG----PADKHi 712 human 1172435 635 IVAGAGQFSk------qWaEYILfAALLLVVCVIFAIMARFYTYINPAEIEAQFD----EDEKKn 689 human 19113209 529 CISSTAVNPk------lTwMYTGiAVTAFIAGIMFWVCFHHYDAMEDEQNQLEFKRNDALTKKDV 587 fission yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",