117794    408 ANLDISRSNLEVIPVKIYPYAHeLISLNVSHNLSLDLP-LDFMER------------CVK-LKRLDISNNLRSPRGKPIT 473  fission yeast
7298532       --------------------------------------------------------------------------------      fruit fly
1176807   141 NHVDASDEQLTLIPEQILNNEArVQILNLRRNSLISRPpTEKVQKsmaplgyiddlyRVHsLQVIDLSANQILSFPIQLT 220  Caenorhabditis el...
27500081      --------------------------------------------------------------------------------      human
20558275  128 SSVDLSCCSLEHLPANLFYSQD-LTHLNLKQNFLRQNPsLPAARGlne-------lqRFTkLKSLNLSNNHLGDFPLAVC 199  human
1169151   797 vdlrnmdlttppiifyqhtseiesldvsnnANIFLP---LEFIES------------SIK-LLSLRMVNIRASKFPSNIT 860  baker's yeast

117794    474 ALRQLEVLNMSRNDIYELDpliFSGLSRNSLKELNIANNKLFFLPHSTRYLVNLTYLDLSYNNFVTFPLIITELSQLETL 553  fission yeast
7298532     1 ----------------------------------MLKATRKQADP-----YKS--KLKVSASHSGPHPLPVEVTAAEEEQ 39   fruit fly
1176807   221 LLSHLRQLNLSSNYISSVP---SECSNMRRLQYLNLSNNQLDTLPDSISELQNLQSLDISFNQFSQIPPCLFHLTLEMWR 297  Caenorhabditis el...
27500081    1 --mqlerpggldtlykfsqlkglnlshnklglfpillceistltelnlscngfhdlpsqignllnlqtlcldgnflttlp 78   human
20558275  200 SIPTLAELNVSCNALRSVP---AAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKL 276  human
1169151   861 KAYKLVSLELQRNFIRKVP---NSIMKLSNLTILNLQCNELESLPAGFVELKNLQLLDLSSNKFMHYPEVINYCTNLLQI 937  baker's yeast

117794    554 NFSHN-LLSQISSKIGslvkLKHLYLQFNDLSNRLPQEIGLLKNleTIDLSYNAITnIASLSECPKLNSINVACNLLSFY 632  fission yeast
7298532    40 AAT--------FGQTS----PQKLSLKGSQLGGSILIGNYNYLT--QLEVCENEME-VLDLSSLAQLETLKCSRNKLMEL 104  fruit fly
1176807   298 LAGNNiEKIDRVGEMQ----IQKIDLRRNVLDTSFRLDIENITH---LDLRDNSMIsTVHLTNLRFLKVIHCERLQLSSL 370  Caenorhabditis el...
27500081   79 eelgnlqqlsslgisfnnfsqipevyekltmldrvvmagnclevlnlgvlnrmnhikhvdlrmnhlktmvienlegnkhi 158  human
20558275  277 CMSGNcVETLRLQALRkmphIKHVDLRLNVIRKLIADEVDFLQHvtQLDLRDNKLG-DLDAMIFNNIEVLHCERNQLVTL 355  human
1169151   938 DLSYN--KIQSLPQSTky-lVKLAKMNLSHNKLNFIGDLSEMTDlrTLNLRYNRIS--SIKTNASNLQNLFLTDNRISNF 1012 baker's yeast

117794    633 EYSNPSATFIDFSFCPLT---TIDPAFSYSNLVYFDISHAKLIGLKdSVIETLVNVETVKVNYNHF--TSISDAISAMQN 707  fission yeast
7298532   105 IINGTNLQTLVADHNYLHnisTTNTHPVPLKLQRIDISHNNFSELP-NWVGACASLTAINASHNRLnnVAVLLRNYRITE 183  fruit fly
1176807   371 HLSGESLTHVYADHNLLD---SLVVMPLPQNLQTLSLSFNHFRNLP-DWISDCPNLTFLRANNNSL--VALPERIFYSQS 444  Caenorhabditis el...
27500081  159 thvdlrdnrltdldlsslcsleqlhcgrnqlreltlsgfslrtlyassnrltavnvypvpslltfldlsrnllecvpdwa 238  human
20558275  356 DICGYFLKALYASSNELV---QLDVYPVPNYLSYMDVSRNRLENVP-EWVCESRKLEVLDIGHNQI--CELPARLFCNSS 429  human
1169151  1013 EDTLPKLRALEIQENPITs--ISFKDFYPKNMTSLTLNKAQLSSIPgELLTKLSFLEKLELNQNNL--TRLPQEISKLTK 1088 baker's yeast

117794    708 LKYLSCTNCEMSYVSPNLGKLKHLVHLDLHANNIKIFPEevwqvSSLKVVNLSSNILEKIKLPVATSKkltrtisqlkim 787  fission yeast
7298532   184 LVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPD-----NFFAVTHARLETLNVSCNKLSTLP------------ 246  fruit fly
1176807   445 LRSIFAFINEIEHIPDFGE-ENCLETLILYKNKLSSLPK-----HFFSILPR-LRQLNISSNFIELLP------------ 505  Caenorhabditis el...
27500081  239 ceakkievldvsynlltevpvrilsslslrklmlghnhvqnlptlvehiplevldlqhnaltrlpdtlfskalnlrylna 318  human
20558275  430 LRKLLAGHNQLARLPERLE-RTSVEVLDVQHNQLLELPP-----NLLMKADS-LRFLNASANKLESLPp----------- 491  human
1169151  1089 LVFLSVARNKLEYIPPELSQLKSLRTLDLHSNNIRDFVDgm-enLELTSLNISSNAFGNSSLENSFYHn----------- 1156 baker's yeast

117794    788 rtlsgnpvsslSSQEFVMPTVEELYLVDNRLGNDCFTALEYFKCLKVLNLSYNYLTEIPSKFFQNFSDLKHLFVSGNELA 867  fission yeast
7298532   247 -----------RYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQ 315  fruit fly
1176807   506 -----------YFDGSSFCRLQILRCANNYLTENSVPVIVNMKHLKIIDLSHNRLNSFDDSALSSLELLEDLNLSSNRLT 574  Caenorhabditis el...
27500081  319 sansleslpsactgeeslsMLQLLYLTNNLLTDQCIPVLVGHLHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLK 398  human
20558275  492 ----------aTLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLK 561  human
1169151  1157 ----------mSYGSKLSKSLMFFIAADNQFDDAMWPLFNCFVNLKVLNLSYN--N-FSDVSHMKLESITELYLSGNKLT 1223 baker's yeast

117794    868 NLS-ISSTAQVLLETLYANGNRLSSFPkNEALSKSLRFLDISTNNLQNLAVEKAEKKsltklPQLEYLNLSGNTWfrfs- 945  fission yeast
7298532   316 QLP-EEVATLGQLRVLRCCNNLLLCTP-QLAKLAMLKVLDLSHNHLDRVNLLALVPS-----RNLKYLDLSGNLQ----- 383  fruit fly
1176807   575 RLA-DCLALLPCLQVLRAHSNQLVHVP-EFRASNQLHTIDVSSNNISLGTLQFKAP------PNLRHFDVTCNS------ 640  Caenorhabditis el...
27500081  399 TIP-TTIANCKRLHTLVAHSNNISIFP-EILQLPQIQFVDLSCNDLTEILIPEALP------ATLQDLDLTGNTN----- 465  human
20558275  562 AIP-TTIMNCRRMHTVIAHSNCIEVFP-EVMQLPEIKCVDLSCNELSEVTLPENLP------PKLQELDLTGNPR----- 628  human
1169151  1224 TLSgDTVLKWSSLKTLMLNSNQMLSLPaELSNLSQLSVFDVGANQLKYNISNYHYDWnwrnnKELKYLNFSGNRRfeiks 1303 baker's yeast

117794    946 ----ehedTNFTKSYLKNLKFLSIMDLNTKfsNAPSDVLNHFIQRnspqpnilrYGVCGYLSRSIPVISACELVVNNFLH 1021 fission yeast
7298532   384 --------LQVDEQQFKVCQSQSQRHWSLV---DVSGNNRAALPT---------TKIRQVSAQRNQNKTSGPWTMG---- 439  fruit fly
1176807   641 --------GDFDTENFPENAKMHSKMNTIN---ISEGSQNLFGFQ---------IGVSGSRGMKNKQCIRQVRVEN---- 696  Caenorhabditis el...
27500081  466 --------LVLEHKTLDIFSHITTLKIDQKplPTTDSTVTSTFWS---------HGLAEMAGQRNKLCVSALAMDSFAEG 528  human
20558275  629 --------LVLDHKTLELLNNIRCFKIDQP--STGDASGAPAVWS---------HGYTEASGVKNKLCVAALSVNNFCDN 689  human
1169151  1304 fishdidaDLSDLTVLPQLKVLGLMDVTLNttKVPDENVNFRLRTtasiingmrYGVADTLGQRDYVSSRDVTFERFRGN 1383 baker's yeast

117794   1022 PQSSLYCVLDSDISagk-nnRVLKFVYDNLASCLAHEINAADSSSEQic-naLRRGFLRLNKKLgnvihydlrkSSEGDV 1099 fission yeast
7298532   440 ----FAETPGSGDC------RKLSVYQLRAANYGGSDEALYG----------MFEALEGRGRAA----------QEMSHL 489  fruit fly
1176807   697 ---TFGFIDGGSNS------YMSSSICRFMTSYLKENVSMD-----------IRSILLRCHCEL----------GEEGER 746  Caenorhabditis el...
27500081  529 VGAVYGMFDGDRNE------ELPRLLQCTMADVLLEEVQQSTNDTVF-----MANTFLVSHRKL----------GMAGQK 587  human
20558275  690 REALYGVFDGDRNV------EVPYLLQCTMSDILAEELQKTKNEEEY-----MVNTFIVMQRKL----------GTAGQK 748  human
1169151  1384 DDECLLCLHDSKNQnadyghNISRIVRDIYDKILIRQLERYGDETDDniktaLRFSFLQLNKEIn---------GMLNSV 1454 baker's yeast

117794   1100 DSNYVTTMNISEKGYSMDSScldigvsiilvyvrdTRAFVANVGTSMAIMSTRNDSEPTTLSVMHDVyNRDEIRRIVDSC 1179 fission yeast
7298532   490 VPDLMKQEQMVKDSAVRDYM---------------KFTLLAAQQQCGSVRSAALFHLTRTRAP-SKV-RPLKSKRYVLRM 552  fruit fly
1176807   747 LGASVMIIRVHEKRLEIAST---------------GTMSAAIARNQKLKMIINGR---------YEI-DDDEYSRIREAH 801  Caenorhabditis el...
27500081  588 LGSSALLCYIRPDTADPASS---------------FSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQ-DPEEAQRVKDQK 651  human
20558275  749 LGGAAVLCHIKHDPVDPGGS---------------FTLTSANVGKCQTVLCRNGKPLPLSRSYIMS--CEEELKRIKQHK 811  human
1169151  1455 DNGADVANLSYADLLSGACStviy--------irgKKLFAANLGDCMAILSKNNGDYQTLTKQHLPT-KREEYERIRISG 1525 baker's yeast

117794   1180 GFIS--GEIKS---TTTRAIGRLSQFP---GVQAVPYVNVQYLSELNEFIILANQEFWSVLSKRTVIDVVRaNRHSPLLA 1251 fission yeast
7298532   553 ASTGglDAYLIrrtSQLRLTKPDVIQKdqiHSMPDPHVLELILSNDDEYLVVGNAQLWSVMDIDRAAREIR-KEENSLLA 631  fruit fly
1176807   802 GFVDe-ENRINgviGSSRQIGHFSTFP---VVLPTHSYRNIQLNEQIEGLIVGNNMIWNMLSIDDLNSTFH-NNRSPIVV 876  Caenorhabditis el...
27500081  652 AIITe-DNKVNgvtCCTRMLGCTYLYP---WILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVR-HVQDPLAA 726  human
20558275  812 AIITe-DGKVNgvtESTRILGYTFLHP---SVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVR-NVPDALAA 886  human
1169151  1526 GYVN--NGKLDgvvDVSRAVGFFDLLP---HIHASPDISVVTLTKADEMLIVATHKLWEYMDVDTVCDIAReNSTDPLRA 1600 baker's yeast

117794   1252 STKLRDYAIAYGAEKNVLVVIVELNGLFEenslnfnqlRGDEKTLaisEKNDNMSFVQDLPDdssLARMNReVSPPKGCI 1331 fission yeast
7298532   632 AKRLVDIAQSFAAAESLSVIVVRFRHLGT---------DVDHLIR----------ELKQSVR----KKPQP-VSLPLSSG 687  fruit fly
1176807   877 AKKIQDQLQSYDYGGNSNILVLRRIKPQM---------TFNGFST-------------SST-------KNQ--VTPDIAI 925  Caenorhabditis el...
27500081  727 AKKLCTLAQSYGCQDNVGAMVVYLNIGEEg--------CTCEMNG---LTLPGPVGFASTTt--iKDAPKP--ATPSSSS 791  human
20558275  887 AKKLCTLAQSYGCHDSISAVVVQLSVTEDs-------fCCCELSAggaVPPPSPGIFPPSVNmviKDRPSDgLGVPSSSS 959  human
1169151  1601 AAELKDHAMAYGCTENITILCLALYENIQ---------QQNRFTLnknSLMTRRSTFEDTT----LRRLQPeISPPTGNL 1667 baker's yeast

117794   1332 AMVFtdiknstllwerhpiamRSAIKTHNTIMRRQLRATGGYEVKTEGDAFMVCFQTVPAaLLWCFSVQLQLLS-ADWPN 1410 fission yeast
7298532   688 SVCK-----------------RTCCDRSNACRHRAIEQEPLAGRSSPSGQSDRDLLAKDK-DDEFVLAHARVL---QEEQ 746  fruit fly
1176807   926 PKID-----------------EQLVLAVPALILPEYH--PSPPVPPPIPAIRHRTPSPPP-PPLPSSTPPPVS---SEHE 982  Caenorhabditis el...
27500081  792 GIAS-----------------EFSSEMSTSEVSSEVG--STASDEHNAGGLDTALLPRP--ERRCSLHPTPTSGlFQRQP 850  human
20558275  960 GMAS-----------------EISSELSTSEMSSEVG--STASDEPPPGALSENSPAYPS-EQRCMLHPICLSNsFQRQL 1019 human
1169151  1668 AMVFtdiksstflwelfpnamRTAIKTHNDIMRRQLRIYGGYEVKTEGDAFMVAFPTPTSgLTWCLSVQLKLLD-AQWPE 1746 baker's yeast

117794   1411 EIVESVQgrlVLGSKNevlyrglsvrigvnygvtvseLDPITRRmdYYGPVVNRTSRVVSVADggq-------------- 1476 fission yeast
7298532   747 QLEMLDE---TESVSE---------------------SVLSEEQ--FKCWEYMLEQNTQLLFD----------------- 783  fruit fly
1176807   983 EINVRQS---STLSGG---------------------YTLSIDR--FYSSSSTVSSRKQFNET----------------- 1019 Caenorhabditis el...
27500081  851 SSATFSS---NQSDNG---------------------LDSDDDQ--PVEGVITNGSKVEVEVD----------------- 887  human
20558275 1020 SSATFSS---AFSDNG---------------------LDSDDEE--PIEGVFTNGSRVEVEVD----------------- 1056 human
1169151  1747 EITSVQDgcqVTDRNGniiyqglsvrmgihwgcpvpeLDLVTQRmdYLGPMVNKAARVQGVADggqiamssdfysefnki 1826 baker's yeast

117794   1477 iaVSAEVVSVLNQLDSETMSSEKTNVNEMEVRALKQIgyiihnlgefkLKGLDTTEMISLVYPvqlQGRLERLIKSRSLG 1556 fission yeast
7298532   784 --KELNTISKSFTKQRTVPNAIMAATVLPERNDFTSN-----------LMRTVTNKFISTSTP---QLPQPITTSVPLGS 847  fruit fly
1176807  1020 --RDLLSKSLKLSPPNTVTFNI---------------------------------------------------------- 1039 Caenorhabditis el...
27500081  888 --IHCCRGRDLENSPPLIESSPTLCSEEHARGSCFGI-----------RRQNSVNSGMLLPMS---KDRMELQKSPSTSC 951  human
20558275 1057 --IHCSRAKEKEKQQHLLQ-VP--AEAS--------------------------DEGIVISAN---EDEPGLPRKADFSA 1102 human
1169151  1827 mkYHERVVKGKESLKEVYGEEIIGEVLEREIAMLESIgwaffdfgehkLKGLETKELVTIAYPkilASRHEFASEDEQSK 1906 baker's yeast

117794   1557 TPTALpetqTYTPVRSRSnsLRPMLARLSDSKSVHGEEGGSGKRSVSSLRNVSPSESTGGYEGCIFDdqqyQLLYELCER 1636 fission yeast
7298532   848 YHQVK----QAPPGHFGS--ALSFQQAHSYGYNLFDAKPRPKFHGGTVKRSAGPNSAYFGSLQRLMP----YNFEYDFAV 917  fruit fly
1176807       --------------------------------------------------------------------------------      Caenorhabditis el...
27500081  952 L--------YGKKLSNGS--IVPLEDSLNLIEVATEVPKRKTG-YFAAPTQMEPE------DQFVVP----HDLEEEVKE 1010 human
20558275 1103 VG--T----IGRRRANGS--VAPQERSHNVIEVATDAPLRKPGGYFAAPAQPDPD------DQFIIP----PELEEEVKE 1164 human
1169151  1907 LINET----MLFRLRVISnrLESIMSALSGGFIELDSRTEGSYIKFNPKVENGIMQSISEKDALLFFdhviTRIESSVAL 1982 baker's yeast