14110387 497 KGNTETSASASQTNH--VKDVKKIKiEHAPSpssgGtLKNDKAKTKPplqvtkvennlivdKATKKAVIvgkesksaa-- 572 human 7296451 518 PSSASSESSASRSRSp-TSRDLKHKrEEYIKkiseTsLFAELVKDRHkrqkalkeiierqeENSNSNSNgaltindnsss 596 fruit fly 15238314 -------------------------------------------------------------------------------- thale cress 19173504 -------------------------------------------------------------------------------- Encephalitozoon c... 19074896 -------------------------------------------------------------------------------- Encephalitozoon c... 14110390 497 KGNTETSASASQTNH--VKDVKKIKiEHAPSpssgGtLKNDKAKTKPplqvtkvennlivdKATKKAVIvgkesksaa-- 572 human 12643825 498 QGTRDSKPIALKEEI--VTPKETETsEKETPpplpTiASPPPPLPTTtpppqtpplpplppIPALPQQPplppsqpafsq 575 human 19115305 5 KSTIYRRQGTEPNSHfrRTVEEKSQlSGTNEeslgGhTLSSNAFKNNsssispsssakdprEQRKRTFPlndthssrar- 83 fission yeast 19112408 -------------------------------------------------------------------------------- fission yeast 416848 -------------------------------------------------------------------------------- baker's yeast
14110387 573 --------------tkeesvslkEKTkPLtpsiGAKEKEqhvalvtstlpplp----lppmlpedkeadsLRGNISVKAv 634 human 7296451 597 vdgntpnaadgrsapgsgtpaaaSTTsNGlqalGSKPDLdlnnipmpnkqndsvvsnpasnadvpdsvaqLKQPLLVPPf 676 fruit fly 15238314 -------------------------------------------------------------------------------- thale cress 19173504 -------------------------------------------------------------------------------- Encephalitozoon c... 19074896 -------------------------------------------------------------------------------- Encephalitozoon c... 14110390 573 --------------tkeesvslkEKTkPLtpsiGAKEKEqhvalvtstlpplp----lppmlpedkeadsLRGNISVKAv 634 human 12643825 576 vpasst-stlppsthsktsavssQANsQPpvqvSVKTQVsvtaaiphlktstlpplplppllpggddmdsPKETLPSKPv 654 human 19115305 84 -------------qherpfrsrkSRRrKGkkafSPRPGSppspsfyrsgsqkrarnlttkdyfakrsessSSASVSPISp 150 fission yeast 19112408 -------------------------------------------------------------------------------- fission yeast 416848 1 -----------------------MSYnNGntysKSYSRNnkrplfgkrspnpqslarppppkrirtdsgyQSNMDNISSh 57 baker's yeast
14110387 635 kkeVEKKlRCLLAdlplpp---------elpggdDLSKSPEEKKTTT----QLHSKRRPKICGPRYGETKEkd------- 694 human 7296451 677 sasKNNIkPKSLTslplppgmnvldlagarspspGQKKESDEKNVTSsgsaNKSVLNLPMPPVIPGSEELSgdddvidsp 756 fruit fly 15238314 1 -----------------------------------------------------MAAAAFGQLN--LEEPPP--------- 16 thale cress 19173504 -------------------------------------------------------------------------------- Encephalitozoon c... 19074896 1 ------------------------------------------------------------MEPAEEGEILAh-------- 12 Encephalitozoon c... 14110390 635 kkeVEKKlRCLLAdlplpp---------elpggdDLSKSPEEKKTTT----QLHSKRRPKICGPRYGETKEkd------- 694 human 12643825 655 kkeKEQRtRHLLTdlplpp---------elpggdLSPPDSPEPKAITp--pQQPYKKRPKICCPRYGERRQte------- 716 human 19115305 151 sanRNDSkRQASSfrrsppssvhmkpsafngrkvSRRPSSSPPPIPSip-hETTSSDTQKKSSVSSGFPENkhgkfhfhi 229 fission yeast 19112408 1 -----------------------------------------MKRSSS----VSVEDEKSARRKLDVVPKLH--------- 26 fission yeast 416848 58 rvnSNDQpGHTKSrgnnnlsryndtsfqtssryqGSRYNNNNTSYENrpksIKRDETKAEFLSHLPKGPKSveksrynns 137 baker's yeast
14110387 695 -------------------------------------iDWGKLCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVR 737 human 7296451 757 edfdapavgtvhghgggpgttrqrpvilnrrdsrnnvrDWGERCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVR 836 fruit fly 15238314 17 --------------------------------------IWGSRSVDCFEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIR 58 thale cress 19173504 1 --------------------------------------------MEKYENIKQVGEGAFGQVYKSRRTSDGAVFAIKKMP 36 Encephalitozoon c... 19074896 13 --------------------------------------RRFTATKMEYEKIRIIGEGTFGQVILARKGRAR--YALKKVS 52 Encephalitozoon c... 14110390 695 -------------------------------------iDWGKLCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVR 737 human 12643825 717 -------------------------------------sDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVR 759 human 19115305 230 pnerrsrfdqppskrmaltstaresvpaplpsppsgpiYTYTYPKPAYEKIDQIGEGTYGKVYKAINTVTGDLVALKRIR 309 fission yeast 19112408 27 --------------------------------------FVGCSHLTDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRIL 68 fission yeast 416848 138 sntsndikngyhas--kyynhkgqegrsviakkvpvsvLTQQRSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLR 215 baker's yeast
14110387 738 LDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKedal------dfkkDKGAFYLVFEYMDHDLMGLLESGLVHFNE 811 human 7296451 837 LEHEKEGFPITAVREIKILRQLNHRNIVNLHEIVTDKqdav------efrkDKGSFYLVFEYMDHDLMGLLESGMVDFNE 910 fruit fly 15238314 59 MDNEREGFPITAIREIKILKKLHHENVIHLKEIVTSPgrdrddqgkpdnnkYKGGIYMVFEYMDHDLTGLADRPGLRFTV 138 thale cress 19173504 37 VDR-ETGFPFTAIREIKLCKSVINKHIIGLDEIVFEE---------------G-FIFVVLEYMPYDLTGLLAS-GAKLST 98 Encephalitozoon c... 19074896 53 KEK--EGLSVTTIREVQVLRAMGHPSIVRLIEVVVEP---------------GGDIYMVFPYFPYDLNRFIRSN--KMTC 113 Encephalitozoon c... 14110390 738 LDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKedal------dfkkDKGAFYLVFEYMDHDLMGLLESGLVHFNE 811 human 12643825 760 LDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKqdal------dfkkDKGAFYLVFEYMDHDLMGLLESGLVHFSE 833 human 19115305 310 LEQEKDGFPITTVREVKILQRLRHKNIVRLLEIMVEK----------------SSVYMVFEYMDHDLTGVLLNSQLHFTP 373 fission yeast 19112408 69 MHTEKEGFPITAIREIKILKSIKHENIIPLSDMTVVRadk--------khrRRGSIYMVTPYMDHDLSGLLENPSVKFTE 140 fission yeast 416848 216 LQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVES---------------QKTVYMIFEYADNDLSGLLLNKEVQISH 280 baker's yeast
14110387 812 NHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP------------YTNKVITLWY 879 human 7296451 911 ENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERp-----------YTNKVITLWY 979 fruit fly 15238314 139 PQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGN------------LTNRVITLWY 206 thale cress 19173504 99 DQIRSITSQLIEAVSSMHGMGLVHRDIKPSNILLDCHGMLKLTDFGLTR--EISG--M------------MTNRVCTLWY 162 Encephalitozoon c... 19074896 114 SEIKHIFYQIAQGVCYIHSKGIMHRDLKSANILLDQKLNASIADFGMAR-YTTKTGA-------------YTPGMVTLWY 179 Encephalitozoon c... 14110390 812 NHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP------------YTNKVITLWY 879 human 12643825 834 DHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRP------------YTNKVITLWY 901 human 19115305 374 GNIKHLSKQIFEALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSAN------------YTNRVITLWF 441 fission yeast 19112408 141 PQIKCYMKQLFAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANknpglpppnrreYTGCVVTRWY 220 fission yeast 416848 281 SQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLAR--KMNSRAD------------YTNRVITLWY 346 baker's yeast
14110387 880 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAV---WPdVIKLP--YFNTMKPKK 954 human 7296451 980 RPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAV---WPnVIKLP--LFHTLKQKK 1054 fruit fly 15238314 207 RPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGSPDESN---WPgVSKMP--WYNQMKSSR 281 thale cress 19173504 163 RAPELLLGETSYSLKVDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEELGIPQDKYk--WS---DLL--DVDIYSKSR 235 Encephalitozoon c... 19074896 180 RAPEILLGSSSYTYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLEMVIHACGSINENS---YPgVQDLP--GFRNFRLPQ 254 Encephalitozoon c... 14110390 880 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAV---WPdVIKLP--YFNTMKPKK 954 human 12643825 902 RPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAV---WPdVIKLP--YFNTMKPKK 976 human 19115305 442 RPPELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPDVHS---WPeVKNLP--WYELLKPVE 516 fission yeast 19112408 221 RSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRLCGSPTQATmpnWE---KLP--GCEGVRSFP 295 fission yeast 416848 347 RPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINS---WPtLYDMPwfFMIMPQQTT 423 baker's yeast
14110387 955 QYRRKLREE--FVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLrDVEPSKMPPPDLPL--WQDCHELWSKKRRRQKQ 1030 human 7296451 1055 THRRRLRED--FEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLrKINPDEMPTPQLPT--WQDCHELWSKKRRRQMR 1130 fruit fly 15238314 282 PLKRRVREI--YRHFDRHALELLEKMLVLDPSQRICAKDALDAEYF-WTDPLPCDPKSLPT--YESSHEFQTKKKRQQMR 356 thale cress 19173504 236 STEEIIAERy-GHLFDEEELKVLSGFLCLTSRKR---LSVANSRYF--TVISSHKNTYIPLs-FEEAHELYTKERKETKK 308 Encephalitozoon c... 19074896 255 S-PRRIEGI--IRKHDASAVELVSKMLCLDPSKRITVEQVVGSKYFeHEARRDASSAGLQGcsYREDRLSLSKRKNVD-- 329 Encephalitozoon c... 14110390 955 QYRRKLREE--FVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLrDVEPSKMPPPDLPL--WQDCHELWSKKRRRQKQ 1030 human 12643825 977 QYRRRLREE--FSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLkDVELSKMAPPDLPH--WQDCHELWSKKRRRQRQ 1052 human 19115305 517 EKKSRFVETf-KEILSPAAIDLCQKLLALNPFCRPSAHETLMHEYFtSESPPPEPAVILKNm-QGSWHEWESKKRKSKR- 593 fission yeast 19112408 296 SHPRTLETA--FFTFGKEMTSLCGAILTLNPDERLSASMALEHEYF-TTPPYPANPSELQS--YSASHEYDKRRKREQRD 370 fission yeast 416848 424 KYVNNFSEKfkSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYF--KEEPKPEPLVLDG--LVSCHEYEVKLARKQKR 499 baker's yeast
14110387 1031 MGMtdd--vsTIKAPRKDLSLG----LDDSRTNTPQGVLPSSQLKSQGSsnvaPvktgpgqhlnhselaillnllqskts 1104 human 7296451 1131 EQQ-------ESLPPTVIASTK----YQQHGATMVGDA------------------------------------------ 1157 fruit fly 15238314 357 HNE-------EAAKKQKLQHPQ----QQHSRLPPQQHGVGQSHAAPLWPa---G-------------------------- 396 thale cress 19173504 309 P------------------------------------------------------------------------------- 309 Encephalitozoon c... 19074896 -------------------------------------------------------------------------------- Encephalitozoon c... 14110390 1031 MGMtdd--vsTIKAPRKDLSLG----LDDSRTNTPQGVLPSSQLKSQGSsnvaP-------------------------- 1078 human 12643825 1053 SGVvveepppSKTSRKETTSGTstepVKNSSPAPPQPAPGKVESGAGDAiglaDitqqlnqselavllnllqsqtdlsip 1132 human 19115305 -------------------------------------------------------------------------------- fission yeast 19112408 371 ANShafeqtaNGKRQFRFMTRGpsdpWYGIRRPNYNSQPQYQRGSYNREggnmDrsrnvnyqpkrqqnfkplts------ 444 fission yeast 416848 500 PNIlstntnnKGNGNSNNNNNNnnddDDK--------------------------------------------------- 528 baker's yeast
14110387 1105 vnmadfvqvlnikvnsetqqqlnkinlpagilATGEKQTDPSTPQQESSk----pLGG-IQPSSQTiQPKMETDAaqaav 1179 human 7296451 -------------------------------------------------------------------------------- fruit fly 15238314 397 --------------------------------PNHPMNNNAPPPQIPAG------GHYyGGKPRGG--APVPNRYp---- 432 thale cress 19173504 -------------------------------------------------------------------------------- Encephalitozoon c... 19074896 -------------------------------------------------------------------------------- Encephalitozoon c... 14110390 1079 ----------------------------------GEKQTDPSTPQQESSk----pLGG-IQPSSQTiQPKMETDAaqaav 1119 human 12643825 1133 qma-qllnihsnpemqqqlealnqsisalteaTSQQQDSETMAPEESLKeapsapVILpSAEQMTLeASSTPADMqnila 1211 human 19115305 -------------------------------------------------------------------------------- fission yeast 19112408 445 -------------dlpqknsefsetnamnqtsNHSHADGQRYYRPEQDRsqrlrnPSDyGRQGRQSsQSQQPAWNvssry 511 fission yeast 416848 -------------------------------------------------------------------------------- baker's yeast
14110387 1180 qsafavllTQLIKAqqskqkdvlleereNGSGHEASlQLRPPPEPSTpvsGQDDLIQHQdmrileltpepDRPRILPPDQ 1259 human 7296451 -------------------------------------------------------------------------------- fruit fly 15238314 433 -------pSGNQTGgy----------nnQSRGGYSSgAYPPQGRGAPygaGPRGPSGGy-----------GVGPPNYSQG 484 thale cress 19173504 -------------------------------------------------------------------------------- Encephalitozoon c... 19074896 -------------------------------------------------------------------------------- Encephalitozoon c... 14110390 1120 qsafavllTQLIKAqqskqkdvlleereNGSGHEASlQLRPPPEPSTpvsGQDDLIQHQdmrileltpepDRPRILPPDQ 1199 human 12643825 1212 vllsqlmkTQEPAGsleennsdknsgpqGPRRTPTMpQEEAAACPPHilpPEKRPPEPPgppppppppplVEGDLSSAPQ 1291 human 19115305 -------------------------------------------------------------------------------- fission yeast 19112408 512 qnnskvqtTSRASEnadtnktqhnikyiDSYVPEYSiARQSANQKTNeqhPSSTSLHQQstsdlkspsfhENSNVDDTPK 591 fission yeast 416848 -------------------------------------------------------------------------------- baker's yeast
14110387 1260 RppeppepppvteedldyrtenqhVpTTSSSL 1291 human 7296451 -------------------------------- fruit fly 15238314 485 Gg----------------------QyGGSGGS 494 thale cress 19173504 -------------------------------- Encephalitozoon cuniculi 19074896 -------------------------------- Encephalitozoon cuniculi 14110390 1200 RppeppepppvteedldyrtenqhVpTTSSSL 1231 human 12643825 1292 ElnpavtaallqllsqpeaeppghLpHEHQAL 1323 human 19115305 -------------------------------- fission yeast 19112408 -------------------------------- fission yeast 416848 -------------------------------- baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",