1171991 2 EINGAHKSNGGGVDAMLCGGDIK-----------TKNMVIN--AEDPLNWGAAAE--------------------QMKGS 48 thale cress 14195018 1 ---------------MELCNQNN-----------HITAVSG----DPLNWNATAE--------------------ALKGS 30 thale cress 21264489 1 ---------MDQIEAMLCGGGEK-----------TKVAVTTktLADPLNWGLAAD--------------------QMKGS 40 thale cress 15237651 1 ---------------MEFRQPN-------------ATALS-----DPLNWNVAAE--------------------ALKGS 27 thale cress 3334229 18 PDDTIHAVAKKSVEKLRRLRPKlpla----ddyfEVRRTVGnsLLDPEDLVSDVLkdsdfiivaasveetedakeAKKQE 93 Caenorhabditis elegans 1170423 20 AQLTVGWLGREAVRRYIKNKPDNggftsvddahfLVRRCKGlgLLDNEDRLEVALennefve-------vviegdAMSPD 92 human
1171991 49 HLD----EVKRMVAEFR----------------KPVVNLGGETLTIGQVAAISTIGnsVKVELSETARAGVNASSDWVME 108 thale cress 14195018 31 HLD----EVKRMVKEYR----------------KEAVKLGGETLTIGQVAAVARGGggSTVELAEEARAGVKASSEWVME 90 thale cress 21264489 41 HLD----EVKKMVEEYR----------------RPVVNLGGETLTIGQVAAISTVGgsVKVELAETSRAGVKASSDWVME 100 thale cress 15237651 28 HLE----EVKKMVKDYR----------------KGTVQLGGETLTIGQVAAVASGG--PTVELSEEARGGVKASSDWVME 85 thale cress 3334229 94 EIDnaraEIEKIDNRRRkvsfadslapmvlappTKLLILDGNSLLPEDLVRCEKGE--CAIQLSMESEDRIRKARTFLEK 171 Caenorhabditis elegans 1170423 93 FIPsq-pEGVYLYSKYRe--------------pEKYIELDGDRLTTEDLVNLGKGR--YKIKLTPTAEKRVQKSREVIDS 155 human
1171991 109 SMNKGTDSYGVTTGFGATSHRRTKNGVALQKELIRFLNAGIFGST---KETSHTLPHSATRAAMLVRINTLLQGFSGIRF 185 thale cress 14195018 91 SMNRGTDSYGVTTGFGATSHRRTKQGGALQNELIRFLNAGIFGPGa--GDTSHTLPKPTTRAAMLVRVNTLLQGYSGIRF 168 thale cress 21264489 101 SMNKGTDSYGVTTGFGATSHRRTKNGTALQTELIRFLNAGIFGNT---KETCHTLPQSATRAAMLVRVNTLLQGYSGIRF 177 thale cress 15237651 86 SMNRDTDTYGITTGFGSSSRRRTDQGAALQKELIRYLNAGIFATGnedDDRSNTLPRPATRAAMLIRVNTLLQGYSGIRF 165 thale cress 3334229 172 IASEHRAVYGVTTGFG-TFSNVTIPPEKLKKLQLNLIRSHATGYG------EPLAPN-RARMLLALRINILAKGHSGISV 243 Caenorhabditis elegans 1170423 156 IIKEKTVVYGITTGFG-KFARTVIPINKLQELQVNLVRSHSSGVG------KPLSPE-RCRMLLALRINVLAKGYSGISL 227 human
1171991 186 EILEAITSFLNNNITPSLPLRGTITASGDLVPLSYIAGLLTGRPNSKATGPNGEALTAEEAFKLAGISSgFFDLQPKEGL 265 thale cress 14195018 169 EILEAITKLLNHEITPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKAVGPSGETLTASEAFKLAGVSS-FFELQPKEGL 247 thale cress 21264489 178 EILEAITSLLNHNISPSLPLRGTITASGDLVPLSYIAGLLTGRPNSKATGPDGESLTAKEAFEKAGISTgFFDLQPKEGL 257 thale cress 15237651 166 EILEAITTLLNCKITPLLPLRGTITASGDLVPLSYIAGFLIGRPNSRSVGPSGEILTALEAFKLAGVSS-FFELRPKEGL 244 thale cress 3334229 244 ENIKKMIAAFNAFCVSYVPQQGTVGCSGDLCPLAHLALGLLGE--GKMWSPTTGWQPADVVLKKNNLEP--LELGPKEGL 319 Caenorhabditis elegans 1170423 228 ETLKQVIEMFNASCLPYVPEKGTVGASGDLAPLSHLALGLVGE--GKMWSPKSGWADAKYVLEAHGLKP--VILKPKEGL 303 human
1171991 266 ALVNGTAVGSGMASMVLFETNVLSVLAEILSAVFAEVMSGKPEFTDHLTHRLKHHPGQIEAAAVMEHILDGSSYMKLAQK 345 thale cress 14195018 248 ALVNGTAVGSGLASTVLFDANILAVLSEVMSAMFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSSYVKEAQL 327 thale cress 21264489 258 ALVNGTAVGSGMASMVLFEANVQAVLAEVLSAIFAEVMSGKPEFTDHLTHRLKHHPGQIEAAAIMEHILDGSSYMKLAQK 337 thale cress 15237651 245 ALVNGTAVGSALASTVLYDANILVVFSEVASAMFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSSYVKEALH 324 thale cress 3334229 320 ALINGTQMVTALGAYTLERAHNIARQADVIAALSLDVLKGTTRAYDPDIHRIRPHRGQNLSALRLRALLHSEANPSQIAE 399 Caenorhabditis elegans 1170423 304 ALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHALRPHRGQIEVAFRFRSLLDSDHHPSEIAE 383 human
1171991 346 LHEMDPLQKPKQDR----YALRTSPQWLGPQIEVIRYATKSIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNT 421 thale cress 14195018 328 LHEMDPLQKPKQDR----YALRTSPQWLGPQIEVIRAATKMIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVAMDNS 403 thale cress 21264489 338 VHEMDPLQKPKQDR----YALRTSPQWLGPQIEVIRQATKSIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNT 413 thale cress 15237651 325 LHKIDPLQKPKQDRyvlgYALRTSPQWLGPQIEVIRAATKMIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVAMDNT 404 thale cress 3334229 400 SHRN---CTKVQDA----YTLRCVPQVHGVVHDTIEFVREIITTEMNSATDNPLVFADREEIISGGNFHGEYPAKALDFL 472 Caenorhabditis elegans 1170423 384 SHRF---CDRVQDA----YTLRCCPQVHGVVNDTIAFVKNIITTELNSATDNPMVFANRGETVSGGNFHGEYPAKALDYL 456 human
1171991 422 RLAIRAIGKLMFAQFSELVNDFYNNGLPSNLTASRNPSLDYGFKGAEIAMASYCSELQYLANPVTSHVQSAEQHNQDVNS 501 thale cress 14195018 404 RLAIASIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNS 483 thale cress 21264489 414 RLAIAAIGKLMFAQFSELVNDFYNNGLPSNLTASSNPSLDYGFKGAEIAMASYCSELQYLANPVTSHVQSAEQHNQDVNS 493 thale cress 15237651 405 RLALASIGKLMFAQFTELVNDFYNNGLPSNLSGGRNPSLDYGLKGAEVAMASYCSELQFLANPVTNHVESASQHNQDVNS 484 thale cress 3334229 473 AIAVAELAQMSERRLERLVNKELS-GLPTFLTP--DGGLNSGFMTVQLCAASLVSENKVLCHPSSVDSIPTSCNQEDHVS 549 Caenorhabditis elegans 1170423 457 AIGIHELAAISERRIERLCNPSLS-ELPAFLVA--EGGLNSGFMIAHCTAAALVSENKALCHPSSVDSLSTSAATEDHVS 533 human
1171991 502 LGLISSRKTSEAVDILKLMSTTFLVAICQAVDLRHLEENLRQTVKNTVSQVAKKVLTTgvngeLHPSRFCEKDLLKVVDR 581 thale cress 14195018 484 LGLISSRKTAEAVDILKLMSTTYLVALCQAVDLRHLEENLKKAVKSAVSQVAKRVLTVgangeLHPSRFTERDVLQVVDR 563 thale cress 21264489 494 LGLISSRKTSEAVDILKLMSTTFLVGICQAVDLRHLEENLRQTVKNTVSQVAKKVLTTgingeLHPSRFCEKDLLKVVDR 573 thale cress 15237651 485 LGLISSRTTAEAVVILKLMSTTYLVALCQAFDLRHLEEILKKAVNEVVSHTAKSVLAI------EPFR-KHDDILGVVNR 557 thale cress 3334229 550 MGGFAARKALTVVEHVEAVLAMELLAACQGIEF--LKPLISTAPLHKIYQLVRSVAPP-----LNEDRYMKPEIDAVLE- 621 Caenorhabditis elegans 1170423 534 MGGWAARKALRVIEHVEQVLAIELLAACQGIEF--LRPLKTTTPLEKVYDLVRSVVRP-----WIKDRFMAPDIEAAHR- 605 human
1171991 582 EQVYTYADDPCSATYPLIQKLRQVIVDHALVNGESEKNavtSIFHKIGAFEEELKAVLPKEVEAARAAYDNGTSAIPNRI 661 thale cress 14195018 564 EYVFSYADDPCSLTYPLMQKLRHILVDHALADPEREANsatSVFHKIGAFEAELKLLLPKEVERVRVEYEEGTSAIANRI 643 thale cress 21264489 574 EQVFTYVDDPCSATYPLMQRLRQVIVDHALSNGETEKNavtSIFQKIGAFEEELKAVLPKEVEAARAAYGNGTAPIPNRI 653 thale cress 15237651 558 EYVFSYVDDPSSLTNPLMQKLRHVLFDKALAEPEGETD---TVFRKIGAFEAELKFLLPKEVERVRTEYENGTFNVANRI 634 thale cress 3334229 622 ---MIRENRIWEAVLPHLETLEAMEELDPDALRQFTKT---------PTGIVQDRSMIPISDDEESIE------------ 677 Caenorhabditis elegans 1170423 606 ---LLLEQKVWEVAAPYIEKYRMEHIPESRPLSPTAFS---------LQFLHKKSTKIPESEDL---------------- 657 human
1171991 662 KECRSYPLYRFVREELGTELLTGEKVTSPGEEFDKVFTAICEGKIIDPMMECLNEWNGAPIPIC 725 thale cress 14195018 644 KECRSYPLYRFVRDELNTELLTGENVRSPGEEFDKVFLAISDGKLIDPLLECLKEWNGAPVSIC 707 thale cress 21264489 654 KECRSYPLYRFVREELGTKLLTGEKVVSPGEEFDKVFTAMCEGKLIDPLMDCLKEWNGAPIPIC 717 thale cress 15237651 635 KKCRSYPLYRFVRNELETRLLTGEDVRSPGEDFDKVFRAISQGKLIDPLFECLKEWNGAPISIC 698 thale cress 3334229 ---------------------------------------------------------------- Caenorhabditis elegans 1170423 ---------------------------------------------------------------- human
Jiyao W et al.(2023). "The conserved domain database in 2023.",