17509291 390 SHrrsqddgelpitssshmkGSRTTGDISKCRGGVVhcfvieEcmlagreynwvecpshgglhmrelapdtvfadienal 469 Caenorhabditis el... 7295585 1 ---------------------MATASLDAl-------------------------------------------------- 9 fruit fly 15224595 -------------------------------------------------------------------------------- thale cress 11346387 -------------------------------------------------------------------------------- thale cress 17544328 1 MDr------------------KPSSSSSTGPPAPvi----qrKt------------------------------------ 22 Caenorhabditis el... 17508441 1 MDns--------------sqSKPSSSSSSHSPSPAAitptqrTt------------------------------------ 30 Caenorhabditis el... 12643557 1 ---------------------MSTASAASSSSSSSAgem-ieAp------------------------------------ 22 human 21735564 1 ---------------------MSTASAASSSSSSSAgem-ieAp------------------------------------ 22 human 21735566 1 ---------------------MSTASAASSSSSSSAgem-ieAp------------------------------------ 22 human 10720099 1 ---------------------MSTASAASSSSSSSAsem-ieAp------------------------------------ 22 house mouse
17509291 470 tihpdqlkrsRMLGRGAFGFVFRATVRQpngelceVAQKMLEPVDPGPGGRPSALAAYKAAADKwkrdsmefacraYCTS 549 Caenorhabditis el... 7295585 10 -------------qAAYVDFSEITLREK-------VGHGSYGVVCKAVWRDKLVAVKEFFASAE------------QKDI 57 fruit fly 15224595 1 -------------MEERRDDESSPTHQG-------------SELAERVKLLSFESQGEALS------------------- 35 thale cress 11346387 1 -------------MGETGDDAG-PSEQGp-----sNQTWWPSEFVEKFGSVYLGSQEETSST------------------ 43 thale cress 17544328 23 ---------rDSDLCLTSDIPKIPPNCIdelnshfLGKGTFGVVEKTKYRKTRDDTYR---------------------- 71 Caenorhabditis el... 17508441 31 ---------rDSGLCSTIDIPEIQAQCIdnlnshyLGKGTYGLVEKTRYRKTRQDDFRPAAIKY------------SSQL 89 Caenorhabditis el... 12643557 23 ---------sQVLNFEEIDYKEIEVEEV-------VGRGAFGVVCKAKWRAKDVAIKQIESESE------------RKAF 74 human 21735564 23 ---------sQVLNFEEIDYKEIEVEEV-------VGRGAFGVVCKAKWRAKDVAIKQIESESE------------RKAF 74 human 21735566 23 ---------sQVLNFEEIDYKEIEVEEV-------VGRGAFGVVCKAKWRAKDVAIKQIESESE------------RKAF 74 human 10720099 23 ---------sQVLNFEEIDYKEIEVEEV-------VGRGAFGVVCKAKWRAKDVAIKQIESESE------------RKAF 74 house mouse
17509291 550 RQELSLLSR------MKHPNVIG---LVGVCTFP----LSLVVELAPLGALNQLLGSHr----kAGTKLSLGVIKESAVQ 612 Caenorhabditis el... 7295585 58 EKEVKQLSR------VKHPNIIA---LHGISSYQqa-tY-LIMEFAEGGSLHNFLHGKv------KPAYSLAHAMSWARQ 120 fruit fly 15224595 36 ---------------KDSPRSVEqdcSPGQRASQhlwdTGILSEPIPNGFYSVVPFLKfeillqDKRVKELYNRLPTPSE 100 thale cress 11346387 44 ---------------KDSPRNLGqdgLPSSTASNilwsTGSLSEPIPNGFYSVIP---------DNRLKQLFNNIPTLED 99 thale cress 17544328 72 --------------------------IYGMYESHrn-gQGLVMEYMDCGCVADLIYDRk------NIEYKMDHVASWMYQ 118 Caenorhabditis el... 17508441 90 HMATLIREAkvmwdlRNHPNIIK---IYGLYKSPrn-gQGVVMEYMDCGSMADLLYDRt------HINYTIDHVASWMFQ 159 Caenorhabditis el... 12643557 75 IVELRQLSR------VNHPNIVK---LYGACLNPv----cLVMEYAEGGSLYNVLHGAe-----pLPYYTAAHAMSWCLQ 136 human 21735564 75 IVELRQLSR------VNHPNIVK---LYGACLNPv----cLVMEYAEGGSLYNVLHGAe-----pLPYYTAAHAMSWCLQ 136 human 21735566 75 IVELRQLSR------VNHPNIVK---LYGACLNPv----cLVMEYAEGGSLYNVLHGAe-----pLPYYTAAHAMSWCLQ 136 human 10720099 75 IVELRQLSR------VNHPNIVK---LYGACLNPv----cLVMEYAEGGSLYNVLHGAe-----pLPYYTAAHAMSWCLQ 136 house mouse
17509291 613 VARALEYLHSAH---IIYRDLKSENVLGWRFPapfspqtdVLLKLGDYGISRSVLPSGGAKGFGGT---EGFMAPEIVRF 686 Caenorhabditis el... 7295585 121 CAEGLAYLHAMTpkpLIHRDVKPLNLLLTNKG--------RNLKICDFGTVADKS--TMMTNNRGS---AAWMAPEVFE- 186 fruit fly 15224595 101 LHA---LGEEGVrieVILVDFQKDKKLAMLKQl-------ITTLVSGSGTNPALVIKkiagtVSDFykrPTLESPSKLAL 170 thale cress 11346387 100 LHA---LGDEGLkadVILVDFQKDKKLFRQKQl-------ITKLVSGLNSKPATIIKkiaglVADVykqSTLQSPAKSTQ 169 thale cress 17544328 119 LSSAVNFFHSKDq---IHRDLKLQNMLLSHHH--------RTLKICDFGTFTSIH--QSMTSNRGS---PITMAPEIFR- 181 Caenorhabditis el... 17508441 160 LSSAVDFFHSNSq---VHRDLKLQNMLLSDRY--------RTMKLCDFGTFTSMH--QSMTSNRGT---PITMAPEVFR- 222 Caenorhabditis el... 12643557 137 CSQGVAYLHSMQpkaLIHRDLKPPNLLLVAGG--------TVLKICDFGTACDIQ--THMTNNKGS---AAWMAPEVFE- 202 human 21735564 137 CSQGVAYLHSMQpkaLIHRDLKPPNLLLVAGG--------TVLKICDFGTACDIQ--THMTNNKGS---AAWMAPEVFE- 202 human 21735566 137 CSQGVAYLHSMQpkaLIHRDLKPPNLLLVAGG--------TVLKICDFGTACDIQ--THMTNNKGS---AAWMAPEVFE- 202 human 10720099 137 CSQGVAYLHSMQpkaLIHRDLKPPNLLLVAGG--------TVLKICDFGTACDIQ--THMTNNKGS---AAWMAPEVFE- 202 house mouse
17509291 687 Ng-EEEYTQKVDCFSFGMFLYELLTLKFPFESEE---HVKERMLDGARPVLLPHEl-lLPTPMLDLLVH---CWSAHPES 758 Caenorhabditis el... 7295585 187 ---GSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDn-aYTIQWKIYKGERPPLLTT---CPKRIEDLMTA---CWKTVPED 256 fruit fly 15224595 171 EenaFLFENHGAQLLGQIKRGCCRARAILFKVLAdtvGLESRLVVGLPSDG-TVNcmdSNKHMSVIVVLnsvELLVDLIR 249 thale cress 11346387 170 S-----FENCGIQLLGQIKHGSCRPRAILFKVLAdtvGLQSRLVVGLPSDG-AAEsvdSYSHISVTVLLnsvEMLVDLMR 243 thale cress 17544328 182 ---CEPYNMKADIFSIGIIMWQMIARDHPYTMNMp-iTPFLYNVATRNLRPHEIE---CNPILSNFYKR---CWSDNPAS 251 Caenorhabditis el... 17508441 223 ---CEQYNMKSDIYSIGIIMWQIIARNHPYRRDLs-vPGLLYNVATANLRPQELE---CNPILSEFYKK---CWNDNADI 292 Caenorhabditis el... 12643557 203 ---GSNYSEKCDVFSWGIILWEVITRRKPFDEIGgpaFRIMWAVHNGTRPPLIKN---LPKPIESLMTR---CWSKDPSQ 273 human 21735564 203 ---GSNYSEKCDVFSWGIILWEVITRRKPFDEIGgpaFRIMWAVHNGTRPPLIKN---LPKPIESLMTR---CWSKDPSQ 273 human 21735566 203 ---GSNYSEKCDVFSWGIILWEVITRRKPFDEIGgpaFRIMWAVHNGTRPPLIKN---LPKPIESLMTR---CWSKDPSQ 273 human 10720099 203 ---GSNYSEKCDVFSWGIILWEVITRRKPFDEIGgpaFRIMWAVHNGTRPPLIKN---LPKPIESLMTR---CWSKDPSQ 273 house mouse
17509291 759 RPSSSQLVGFCAAPEFTHLLDVCELGEALPPTQLMAVGITDEIDDPDDFEAQLWLSGREMvvmgCTQYGFVDQKsieLPH 838 Caenorhabditis el... 7295585 257 RPSMQYIVGVMHEIVKDYTGADKALEYTFVNQQIVTKESDGTVAAQPDSLSSQEGELSPSstqlTPTTAANANVnaiAIS 336 fruit fly 15224595 250 FPGQLVPRSAKAIFMSHISPAGESDSAENDSCDSPLEPNSPLY---ERRDPERSASVV---------------------- 304 thale cress 11346387 244 FPGQLIPLSTKAIFMSHISAAGESDSAENDSCDSPLEPNSPMFGYPEKFDHENAEKDENLslhrKLDGSPNTSGppsRNM 323 thale cress 17544328 252 RPTSADCVEYFRCLRSEYPNGNVPLWDP--------------------------ASGASNtvkiPKS----------QPG 295 Caenorhabditis el... 17508441 293 RPTSSECVEYFTLLKDEYPNGSVPLSDSSTN---GPAETPPPHAHRPTMLGTSSGSGIGSnnrtPTASKLLNPQ---QPG 366 Caenorhabditis el... 12643557 274 RPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTnmeqVPATNDTIKR---LES 350 human 21735564 274 RPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTnmeqVPATNDTIKR---LES 350 human 21735566 274 RPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTnmeqVPATNDTIKR---LES 350 human 10720099 274 RPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTnmeqVPATNDTIKR---LES 350 house mouse
Jiyao W et al.(2023). "The conserved domain database in 2023.",