Conserved Protein Domain Family
OppA

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COG4166: OppA 
ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]
Statistics
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PSSM-Id: 226636
View PSSM: COG4166
Aligned: 88 rows
Threshold Bit Score: 158.338
Threshold Setting Gi: 15828886
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15900290   2 MKSSK--LFALAGVTLL-AATTLAACS-G--SGSS-TKGe--KTFSYIYETDPDNLNYLTTAKAATANITSN-VVDGLLE 71
gi 15895925   1 ---MKnfIRVCIAFMLV--CLILTGCVeKkdESIKtSSE---KKYLVYDIGEISENLYSMKNKSVKNNELLNmLFSGLVR 72
gi 15618120   1 -------MLRFFAVFIStLWLITSGCS----PSQSsKG-----IFVVNMKEMPRSLDPGKTRLIADQTLMRH-LYEGLVE 63
gi 15618122   1 MHRLKptLKSLIPNLLF-LLLTLSSCS----KQKQePLG---KHLVIAMSHDLADLDPRNAYLSRDASLAKA-LYEGLTR 71
gi 15604895   1 MHHRKflAVSIA--FVS-LAFGLTSCY----HKKEePK----DVLRIAICHDPMSLDPRQVFLSKDVSIVKA-LYEGLVR 68
gi 19704648   1 ----MkiFKFLSIFILS---CLLFACGe---EKLEeTEKv--EQIFYTVMPKQEYKLNSQSYSGNERALLTQ-LFEGLTE 67
gi 15828886   1 ---MNkkNIALSIFALSsSALMLVACStQ--ESIAtKNLnldNSTKVDFGVASNPINSLNYIKNSSMDKIRPsLIEGMYK 75
gi 18279087   1 MKKSKskYLTLAGLVLG-TGVLLSACG-N--SSTAs------KTYNYVYSSDPSSLNYLAENRAATSDIVAN-LVDGLLE 69
gi 19856718   1 MKKNR--VFATAGLVLL-AAGVLAACS-S--SKSSdSSAp--KAYGYVYTADPETLDYLISSKNSTTVVTSN-GIDGLFT 71
gi 15639573   1 MRRMRlsRRGILTVVGTlLLLPLFPSEkK--KTHApLPRserKEFVVSFSPYRPVLHPHVASRVDEAQLLTA-LYEGLVT 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15900290  72 NDRYGNFV------PSMAED--WSV--SKDGLTYTYTIRKDAKWYTSEgeeyaAVKAQDFVTGLKYAADKKSDALYL--V 139
gi 15895925  73 EDYNTMEI------KPGLADk-WSL--SPNKLQYTFHIREGLKWSDGD-----DLTAQDVYDFFKQILSSKNNKLYAydL 138
gi 15618120  64 EHSQNGEI------KPALAEs-YTI--SEDGTRYTFKIKN-ILWSNGD-----PLTAQDFVSSWKEILKE--DASSVylY 126
gi 15618122  72 ET--DQGI------ALALAEs-YTL--SKDHKVYTFKLRP-SVWSDGT-----PLTAYDFEKSIKQLYFEEFS-PSIhtL 133
gi 15604895  69 EK--EAAF------QLALAEr-YHQ--SDDGCVYTFFLKN-TFWSNGD-----VVTAYDFEESIKQIYFREIDNPSLrsL 131
gi 19704648  68 LKTEGv--------RLISVLs-IEH--SDDYKEWTFTLRDDLKWSDEE-----KITADTYLDSWLDSLEN--SKSDEi-Y 128
gi 15828886  76 SSISANTAfgnvlkLPSLAFtsWNNqnATSSSTGSELLENPENIFRSNn----FYQISNFSLTTGVAAYNSPNYSSVrgL 151
gi 18279087  70 NDQYGNII------PSLAED--WTV--SQDGLTYTYKLRKDAKWFTSEgeeyaPVTAQDFVTGLQYAADKKSEALYL--V 137
gi 19856718  72 NDNYGNLA------PAVAED--WEV--SKDGLTYTYKIRKGVKWFTSDgeeyaEVTAKDFVNGLKHAADKKSEAMYL--A 139
gi 15639573  78 YDPYDLHP------IPALAQh-WSV--STDGLTWTFYLRDQIFFQNGD-----PITAETFQQSWLNLLNPEWNVPYAsfL 143
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15900290 140 QESIKGLD--AYVKGE-IKDFSQVGIKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSK--GDDFAKATDPSs- 213
gi 15895925 139 NCIYGVNG---YVNGK--TSFDGVAISAEDNNTFQIRLNSPCDYFLKKLAQPIYNIRKTNGDLKNw-TRDYAK------- 205
gi 15618120 127 AFLPIKNAr-AIFDDT--ESPENLGVRALDKRHLEIQLETPCAHFLHFLTLPIFFPVHETLRNYS---TSFEEM------ 194
gi 15618122 134 LG-VIKNSs-AIHNAQ-K-SLETLGIQAKDDLTLVITLEQPFPYFLTLIARPVFSPVHHTLRESY--KKGTPPS--TY-- 203
gi 15604895 132 A--LIKNSh-AVLTGA-L-PVEDLGVRALNAKTLEIVLENPFPYFLEILAHPVFYPVHTSLREYY--KDKRNKR--VFp- 201
gi 19704648 129 RMFVIKGAe-DFYNKK---VDKSSVGLKIQDNKFIVSLNAPIKNFDEWVSNPIFYPIRKENINLS----LDKK------- 193
gi 15828886 152 INNNNNYVsvVFRVNNgLSKWSNGKEVTPQDFIDAAHYILDNNTASQKIVNYLNLNIKNSQAIVDa-QNDYVKKFGTN-- 228
gi 18279087 138 QDSVAGLD--DYITGK-TSDFSTVGVKALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSK--GDDFGKA-DPSs- 210
gi 19856718 140 ENSVKGLA--DYLSGT-STDFSTVGVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSK--GSDFAKPTDPTs- 213
gi 15639573 144 DAVEGARAyrSGTTAD--SHTVGILVEGSDKKTLVVKLAYPAGHFIQMLCHHAFAAVHPTQLASVgtLHARTASASAHkp 221
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15900290 214 --LLYNGPYLLKSIV-T-KSSVEFAKNPN-YWDKDNVHVDK--VKLSFWDgqDTSKPAENFKDG-SLTAARLYPTSAS-F 284
gi 15895925 206 --LKYSGPYIIDKIS---NNTALLKKNNN-FFSKDEVKKEEfkVKYHYNEkdVSAYSTTDFENSkNIDAFSNP------P 273
gi 15618120 195 --PITCGAFRPVSl--EkGLRLHLEKNPM-YHNKSRVKLHK--IIVQFIS--NANTAAILFKHK-KLDWQGPPWGEPI-P 263
gi 15618122 204 ---ISNGPFVLKKHEh--QNYLILEKNPH-YYDHESVKLDR--VTLKIIP--DASTATKLFKSK-SIDWIGSPWSAPI-S 271
gi 15604895 202 --IISNGPFAIQCYEp--QRYLLINKNPL-YHAKHDVLLNS--VCLQIVP--DIHTAMQLFQKN-HIDLVGLPWSSSF-S 270
gi 19704648 194 ---IVNGAFKVSSFN---DDEIILERNEN-YWDSINTKLKE--IKISLIE--DGIMAYEMFPRN-EIDYFGEPFYPMp-- 259
gi 15828886 229 ----YKNPFGRKEYKfDeNRKIFVEDYSKpSWESQNEADQE---YVEKIK--KAASSLGLYTGRvFVEYSNDQIRSFvnA 299
gi 18279087 211 --ILYNGPFLMKALV-S-KSAIEYKKNPN-YWDAKNVFVDD--VKLTYYDgsDQESLERNFTAG-AYTTARLFPNSSS-Y 281
gi 19856718 214 --LLYNGPFLLKGLT-A-KSSVEFVKNEQ-YWDKENVHLDT--INLAYYDgsDQESLERNFTSG-AYSYARLYPTSSN-Y 284
gi 15639573 222 fhPIASGPFELQQMQ---ADRVVLRVNTR-YWDRDALALHA--IVALIAQ--DPAARDAGFNDG-SIHWISG-------- 284
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15900290 285 AELEKSMKDNIVYTQQDSitylvgtniDRQSYKYTSKTSDeqkastkkALLNKD-FRQAIAFGFDRTAYASQLNGQtgaS 363
gi 15895925 274 LSEVNKLKDKGEIDVFKT---------WRTEALYFNMNNLs-------IGSDIN-FRKAITYLVDRNKILKSLSTD---I 333
gi 15618120 264 PEISASLHQDDQLFSLPG---------ASTTWLLFNIQKK--------PWNNAK-LRKALSLAIDKDMLTKVVYQG---L 322
gi 15618122 272 NEDQKVLS-QEKILTYSV---------SSTTLLIYNLQKP--------LIQNKA-LRKAIAHAIDRKSILRLVPSG---- 328
gi 15604895 271 LEEQRNLP-REKLFDYPV---------LSCSVLFCNIHQT--------PLNNPS-LRTALSLAINRETLLKLAGKG---- 327
gi 19704648 260 FDRLNQVNTLPEKLVFPT---------TRYWYISIPNENKe-------NFFDKTeIRKLIYAVSDPEFMGKVILEN---- 319
gi 15828886 300 LPEENKNFNSKSTFIYIK---------EGDEIKKVNLNPN--------PYLDPKqVFEGAQLKAKYSFFAQDDFEL---- 358
gi 18279087 282 EGIKEKYKNNIIYSMQNStsyffnfnlDRKSYNYTSKTSDiekkstqeAVLNKN-FRQAINFAFDRTSYGAQSEGKegaT 360
gi 19856718 285 SKVAEEYKDNIYYTQSGSgiaglgvniDRQSYNYTSKTTDsekvatkkALLNKD-FRQALNFALDRSAYSAQINGKdgaA 363
gi 15639573 285 ALEHSSLQDAATLQIVPL---------LATEYLCFKTAHE--------PTCNAT-LRKALLLATPVEELTARYLFP---- 342
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15900290 364 KILRNLFVPPTFVQADGknfgdmvkeklvtygdewKDVNLADSQDGLYNPEKAKAEFAKAKSALQA--EG-V--QFPIHL 438
gi 15895925 334 LTSENTFVPYELFKSG-------------------K----CEDVFKQPNINLAMQCIDKTNYASGK-----K---IVLIY 382
gi 15618120 323 AEPTDHILHPRLYPGTY--------------------P---ERKRQNERILEAQQLFEEALDELQMtrEDlEkeTLTFST 379
gi 15618122 329 -QEAVTLVPPNLSQLNLq-----------------K------EISTEERQTKARAYFQEAKETLSEkeLAeL--SILYPI 382
gi 15604895 328 -CSATSFVHPQLSQIPAt------------------------TLSQDERIALAKGYLTEALKTLSQedLEkI--TLIYPI 380
gi 19704648 320 -------DSPAIFSHP---------------------------HPSSDILNKAKEDFEKIKENSN--------------- 350
gi 15828886 359 RVDLEDSNPKNINAIYN-------------------------DLLVSNVFLPVNREFVETKAGG---------------- 397
gi 18279087 361 KILRNLVVPPNFVSIKGkdfgevvaskmvnygkewQGINFADGQDPYYNPEKAKAKFAEAKKELEA--KG-V--QFPIHL 435
gi 19856718 364 LAVRNLFVKPDFVSAGEktfgdlvaaqlpaygdewKGVNLADGQDGLFNADKAKAEFAKAKKALEA--DG-V--QFPIHL 438
gi 15639573 343 --ARTLVTPFTGYPVP--------------------------PVVHEYNPARARALLAEAKIGGKT-----ArtPLKILV 389
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15900290 439 DMPVdqTATTKVQRV-QSMKQSLEATLGadNVIIDIQQLQKDEVnniTYFAENAAGEDWDLSDNvGWGPDFADPSTYLDI 517
gi 15895925 383 KDNQieREMCKNFVN-EVNDILEEQNRN----KLNFDIRGYDEK----ALNDAIKKGRYDIYLG-DYNIWYNSAVSFFDM 452
gi 15618120 380 FSFS------YGRIC-QMLREQWKKVLK-----FTIPIVGQEFF----TIQKNFLEGNYSLTVN-QWTAAFIDPMSYLMI 442
gi 15618122 383 DSSN------SSIIA-QEIQRQLKDTLG-----LKIKIQGMEYH---CFLKKRRQ-GDFFIATG-GWIAEYVSPVAFLS- 444
gi 15604895 381 ESVC------LRAVV-QEIRQQLFDVLG-----FKISTLGLEYH---CFLDKRSR-GEFSLATG-NWIADYHQASAFLS- 442
gi 19704648 351 -------------FN--FSETPYIAYFE------NNNLLEKKL---------------LLSTVK-EWIGQFKIPIR---- 389
gi 15828886 398 ----------IDNFGsTLDKFLWNGPFD----IESIEFGPQGN----MILTKRDQYYSSDITLSkKIKVFFADELEVLSL 459
gi 18279087 436 DKTVevTDKVGIQGV-SSIKQSIESVLGsdNVVIDIQQLTSDEFdssGYFAQTAAQKDYDLYHG-GWGPDYQDPSTYLDI 513
gi 19856718 439 DVPVdqASKNYISRI-QSFKQSVETVLGveNVVVDIQQMTSDEFlniTYYAANASSEDWDVSGGvSWGPDYQDPSTYLDI 517
gi 15639573 390 SDT--------EACR--ALALELQKAWT----ALALAVEIWAVRp--ETYREYVQDEKYHVRIV-SWVADFADPMAFLEL 452
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15900290 518 IKPSVGESTktylgfdsgedNVAAKKVGLYDYeklVTEAGDETTDVAKRYDKYAAAQAWLTDS-ALIIPTTSRTGr-pIL 595
gi 15895925 453 WDSKSPLN--------------INYKNVNYDD------YIYSLHNIDGDSDNILKKMEEQLVNdLPVIPLALKND---VV 509
gi 15618120 443 FANPGGIS-------------PYHLQDSHFQT---LLIKITQEHKKHLRNQLIIE-ALDYLEHcHILEPLCHPNLr--IA 503
gi 15618122 445 -ILGN-PR---------------DLTQWRNSDy--EKTLEKLY-LPHAYKENLKR-AEMIIEEeTPIIPLYHGKYi--YA 501
gi 15604895 443 -VLGNGTRY-----------KDFQLINWQNQKy--TNIVAQLL-IQESSDLQLM--AEQLLLKeSPLIPLYHLDYv--YA 503
gi 19704648 390 -VTSNSDS-------------AITFKIEKYLV---GTNNINDLYYYINYKYGTNIKSDGEFLDnLPVIPLLQEYDt--VL 450
gi 15828886 460 LFHEGYIAN-------------TKISNTYLPK---FW-AKEETRKFLTKTSGYGTIALQMNLDkVTNSQSYLQDE---DL 519
gi 18279087 514 FNTNSGG-FlqnlglepgeaNDKAKAVGLDVYtqmLEEANKEQ-DPAKRYEKYADIQAWLIDS-SLVLPSVSRGGt-pSL 589
gi 19856718 518 LKTTSSETTktylg-fdnpnSPSVVQVGLKEYdklVDEAARETSDLNVRYEKYAAAQAWLTDS-SLFIPAMASSGaapVL 595
gi 15639573 453 FRKGSKTHS-------------TGWTHEEFEA---LLTRAGAEPHVLRRWELLAQ-AERILLQeAVVLPLSRLHAl-hAV 514
                       650       660       670
                ....*....|....*....|....*....|...
gi 15900290 596 SKMVpftIPFALSGNKGtsePVLYKYLELQDKA 628
gi 15895925 510 CRKM----QLKGLKENK---YGELIVNSLR--- 532
gi 15618120 504 LNKN----IKNFNLFVR----RTSDFRFIEKL- 527
gi 15618122 502 I-HP----KIQNTFGSL---LGHTDLKNIDILS 526
gi 15604895 504 K-QP----RVSDLQTSS---RGEIDLKRVSLAE 528
gi 19704648 451 SHSN-----VRGLNLTP---SGDIYLKYINMQ- 474
gi 15828886 520 RKAI----YYAINREDI---LSLTNWDSSFPvy 545
gi 18279087 590 RRTVpfaAAYGLTGTKGv---ESYKYLKVQDKI 619
gi 19856718 596 SRIVpftGASAQTGSKGs--DVYFKYLKSQDKV 626
gi 15639573 515 QRRTvrgWYANVLDVHP---FKFISLQEEIKVN 544
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