Conserved Protein Domain Family
LasI

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COG3916: LasI 
N-acyl-L-homoserine lactone synthetase [Signal transduction mechanisms]
Statistics
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PSSM-Id: 226430
View PSSM: COG3916
Aligned: 12 rows
Threshold Bit Score: 235.698
Threshold Setting Gi: 462480
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13475341  12 MIQLITPGLYSEFAGELK-EMHGLRYRVFKERLDWEVQTGGE---METDTFDDLKPVYLLLK--GSDWRIRGCVRLLPTT 85
gi 464915     2 RILTVSPDQYERYRSFLK-QMHRLRATVFGGRLEWDVSIIAG---EERDQYDNFKPSYLLAI--TDSGRVAGCVRLLPAC 75
gi 462480     1 --MIVQIGRREEFDKKLLgEMHKLRAQVFKERKGWDVSVIDE---MEIDGYDALSPYYMLIQedTPEAQVFGCWRILDTT 75
gi 12230962   1 MIELLSESLEGLSAAMIA-ELGRYRHQVFIEKLGWDVVSTSRvrdQEFDQFDHPQTRYIVA---MSRQGICGCARLLPTT 76
gi 20140007   1 --MQTFIHGGGRLPEAVDaALAHYRHQIFVGQLGWQLPMADGr--FERDQYDRDDTVYVVAR--DADGAICGCARLLPTT 74
gi 17549000   1 --MLFG-DRETLKPVAVS-NLGRYRYKVFVERLKWHLPCEAG---HEFDQFDRSDTKHLIAL--GQGEDIVGCARLLPTT 71
gi 15965592   1 MIRIVNGNGRSQHPQAID-EMFRLRKRVFHDFLKWDVKTEGD---WEIDHYDKANPLYVMSYs-PDTGKIRGSLRLLPTL 75
gi 16121288   1 MLEIFDVRYDELTDIRSE-DLYKLRKKTFKDRLNWEVNCSNG---MEFDEYDNSDTRYLLG---IYQGQLICSVRFIELH 73
gi 16122677   5 MLKVFNVNFDRMSENKLD-EIFTLRKITFKDRLDWKVTCIDG---KESDQYDDENTNYLLG---TIDDTLVCSVRFVEMQ 77
gi 13474693   1 MLFCLTTQELMERPDLWE-AVHRLRYQIFVEEMGWEDLRRPDg--FEVDQFDHDEAVHQIV---LRGNEVAGYQRMLPTT 74
gi 13475097   1 MIELIAPGWYGAFADELH-EMHRLRYRVFKERLDWNVRTTGG---FEIDSFDSLKPHYLVLR--DSAGRVRGGVRLLPST 74
gi 13488405   3 RIHLVNWDNRKHYRKVLE-RYFRIRYEIYVKQRRWRAVARPIn--IEIDAFDNEHTLYVLAL--DTNGKIVGGSRLVPTL 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13475341  86 GPTMLRDTFPALLG-EAVAPASPDIWESSRF-ALDLpPSTPKAAGGLAQ-ATYELFAGMIEFGLANNLTRIVTVTDTRME 162
gi 464915    76 GPTMLEQTFSQLLE-MGSLAAHSGMVESSRF-CVDTsLVSRRDASQLHL-ATLTLFAGIIEWSMASGYTEIVTATDLRFE 152
gi 462480    76 GPYMLKNTFPELLH-GKEAPCSPHIWELSRF-AINS---GQKGSLGFSD-CTLEAMRALARYSLQNDIQTLVTVTTVGVE 149
gi 12230962  77 DAYLLKDVFAYLCS--ETPPSDPSVWELSRY--------AASAADDPQL--AMKIFWSSLQCAWYLGASSVVAVTTTAME 144
gi 20140007  75 RPYLLKDVFAPLLMrGVPAPESPGVWELSRFaARSG---ASRARGARPDwAVRPMLASVVQCAAQRGARRLIGVTFVSMV 151
gi 17549000  72 RPYLLESVFPALLN-GQPPPSSPEVWELSRFaAVDFsEDTPSLLKQFSVrAAVELLRISMACAKHCGAKKLVTVSPMGVE 150
gi 15965592  76 GPNMLDDTFPILLG-DNPEIRSASVWESSRF-CIDPeISQDRASNQVTI-AAAELMCGVGEMSLASGISHIVTVTDVFLE 152
gi 16121288  74 LPNMITHTFNALFD-DVALPKR-GYIESSRF-FVDK-TRAKLLFGNHYP-ISYLFFLSIINYSRHNGYTGIYTIVSRAML 148
gi 16122677  78 YPTMITGPFAPYFR-DLDLPID-GFIESSRF-FVEK-ALARDKLGNNGS-LSAILFLSMVNYARNRGYKGILTVVSRGMY 152
gi 13474693  75 RPHLLTEVLTDLSE--GTPPSGPNIWELTRYaVAPG---FRDGRRGVST-VGTELIAGFVEWGLKRGVDKVIIEFEPMWV 148
gi 13475097  75 GPTMLRDVFSRLLE-GRAAPEEPSVWESSRF-ALDLpPSAPKDSGSIAV-ATYELLAGMIEFGLSRLLTHIVTVTDLRME 151
gi 13488405  78 EPHLMSEVFPVLAG--GRPPRAAEIFEWTRFfVVP----SLRTQGAPSP-IAGFVLCGLLETAQRLGIRQISVVCETFWP 150
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 13475341 163 RILRLATWPLSRIGKPQPVGKTEAVAGFLEISHASLLRIRWRG--RLNGPVLWRpilGLPHGPC 224
gi 464915   153 RILKRAGWPMRRLGEPTAIGNTIAIAGRLPADRASFEQVCPPG--YYSIPRIDV---AAIRSAA 211
gi 462480   150 KMMIRAGLDVSRFGPHLKIGIERAVALRIELNAKT--QIALYG----GVLVEQR----LAVS-- 201
gi 12230962 145 RYFVRNGVILQRLGPPQKVKGETLVAISFPAYQERGLEMLLRY----HPEWLQGv--PLSMAV- 201
gi 20140007 152 RLFRRIGVRAHHAGPVRCIGGRPVVACWIDIDASTCAALGIPGasVVPGPALQ----------- 204
gi 17549000 151 RLLAWAGFSWVRAGHPLRFGDDLVVAGYIDVA-------------------------------- 182
gi 15965592 153 RMFRRMGCPGERIADPHRIGSVHAVAIAWEVSRNLLETMKAVA--SIEGTVLDR---PMSLETA 211
gi 16121288 149 TILKRSGWQVEVIKEAHITEKERIYLLHLPIDRDNQARLLLQVnqRLQDPCSVLstwPISLPVM 212
gi 16122677 153 TILKRSGWGITVINQGESEKNEVIYLLHLSIDSNSQQQLIRKIqrVHNIDTHTLaswPLVVPSM 216
gi 13474693 149 LRALQLHFLATPLGYQRTYGNQQVVATLLSFNEHTLDVVRSRR--NHHAPVLARgypDMFGQRR 210
gi 13475097 152 RILRRAGWPLDRIGPPQTIGTTCAVAGCLDVSEESLAAVRHNG--GLGGPVLWA---GALHGRL 210
gi 13488405 151 KRLRALGWTLTELGDVLEHPDGDIIALLIDVTPEAVEQTRRAYg--ISGVLLAE---------- 202
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