Conserved Protein Domain Family
ERG8

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COG3890: ERG8 
Phosphomevalonate kinase [Lipid transport and metabolism]
Statistics
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PSSM-Id: 226407
View PSSM: COG3890
Aligned: 4 rows
Threshold Bit Score: 426.993
Threshold Setting Gi: 19114333
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1706695    1 MSELRaFSAPGKALLAGgylvlDtkYEAFVVGLSArmHAVAHPYGSLQGSdkfeVRVKSKQFkdgeWLYHISpksgfIpv 80  baker's yeast
15595032   1 MDLIS-FSVPGNLLLMG-----E--YTILEEKGLG--LAIAINKRAFFSF-------KKSDS----WRFFSK-----K-- 52  Lyme disease spiroc...
19114333   1 MKVT--CSAPGKVLIAGgyivlDpqYSGLVIGLTAkgYASTTTLDDKCGT----VRVKSPQFinaeWLYNIDwtvspIrv 74  fission yeast
15899698   1 MIKV---SAPGKILWIG-----S--YSVVFGGIS---HVIAVNKRVSCSL----REIKEKDS----LIFHTS-------- 51  Sulfolobus solfatar...
1706695   81 -------sIGGSKNPFIEKVIANVFSYFKPNm-DDYCNRNLFVIdifSDDAYHSQEDSVTEhRGNrrlsfhshrieevpK 152 baker's yeast
15595032  53 --------KKIDDFSLIENRSDFVFKMFAYL--SQNCFFNLENF---AYDVYIDTSNFFFN-DGT--------------K 104 Lyme disease spiroc...
19114333  75 hqiyenceLEKNPNPFVQLALFYVINYFFSTgrQPLCWQDLQVTl-qVDNAYYHQPQLKPDqTSYpkfnflnctlgqvhK 153 fission yeast
15899698  52 --------YGHFKNSGNELINS-VLDTFRER--LSQLPQGYEID-------LYNDKEFIID--GK--------------K 97  Sulfolobus solfatar...
1706695  153 TGLGSSAGLVTVLT-TALASFf--VsdLENN---VDKy-REVIHNLAQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPA 225 baker's yeast
15595032 105 KGFGSSAVVAIGIVcGLFLIH------NATN---VVE--KGEIFKYCLEAYRYSQGGIGSGYDIATSIFGGVIE--FEGG 171 Lyme disease spiroc...
19114333 154 TGLGSSAAMITSLIgSLFLSLrrlTddTGDKslkIDDstKVIVHNLAQIAHCSAQGKVGSGFDVGAATWGSCIYRRFDPK 233 fission yeast
15899698  98 TGLGSSSAATVSLT--ACLYY---A--IHGK---LDL---FEIHKLAQIANYKRQKGIGSGFDIASAVFGSIVYKRFTDL 164 Sulfolobus solfatar...
1706695  226 LISNLp-----DIGSATYGsklahlvdeedwnitiksnhlpsGLTLWMGDIKNGSETVKLVQKVKNWYDSHMPESLKiyt 300 baker's yeast
15595032 172 FNPKCr-----QLGAVEFN-----------------------DFYLMQGLQAIKTTTS--ICEYNKHRNSILDFILK--- 218 Lyme disease spiroc...
19114333 234 LIEQLlvpydeQIKNINFStelrkivskkw--sdvvpfqlpaTYCLLMGDVAGGSSTPGMVKKVQQWQKEN-PEESKn-- 308 fission yeast
15899698 165 DKMDF------YFEKLNLG-----------------------NYDMMLGFTGKSSETVGLVRKFVEKSNLDDFKEIMr-- 213 Sulfolobus solfatar...
1706695  301 ELDHANSRFMDglskldrLHEThddysdqifeSLErndctcqkypeitEVRDAVATIRRSFRKITKESGADIEPPVQTSL 380 baker's yeast
15595032 219 CNLEMKKLVLN-----------------------A--------------SNSKS-ALISSLRRAKELGLAIGEAIGVSAA 260 Lyme disease spiroc...
19114333 309 CFDDLYSRVLSik---ncFLSSe---------SLDs------------ELQSQFRSIRRILQRITVEAKVDIEPLKQTNI 364 fission yeast
15899698 214 LIDEENYMAIK-------LIKLn---------KLD-------------EAVEHIKLGRKYLNYIAERIVGVKLVSKMEEE 264 Sulfolobus solfatar...
1706695  381 LDDCQTLKGVLTCLIPGAGGYDAIAVITKQDVDLRAqtanDKRFSKVQWLDVTqADWGVRKEKDPE 446 baker's yeast
15595032 261 LPSSFDHLLGQCDLIKALGAGNETFLVYRPNIEAFN------LSKIISIVLEN---EGIKFESDKC 317 Lyme disease spirochete
19114333 365 LDNIEQLPGVIGVGVPGAGGFDAQFCLAINHTEIIEnvikTWKDDGVVPMDVSpAFDGLAVE---- 426 fission yeast
15899698 265 LIKIAEEEGALVALSPGAGGGDSIFALGNDLNRVRE----AWSKRGIFIIDVK-EDEGLRLESN-- 323 Sulfolobus solfataricus
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