1LBI


Conserved Protein Domain Family
PurR

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COG1609: PurR 
DNA-binding transcriptional regulator, LacI/PurR family [Transcription]
linked to 3D-structure
Statistics
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PSSM-Id: 224525
View PSSM: COG1609
Aligned: 277 rows
Threshold Bit Score: 41.5258
Threshold Setting Gi: 16124768
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1LBI_A        4 VTLYDVAEYAGVSYQTVSRVVNQAS---HVSAKTREKVEAAMAELNYI-PNRVAQQLAGKqslLIGVATS---------- 69
gi 3025303    2 ATLSDVAKKANVSKMTVSRVINHPE---TVTDELKKLVHSAMKELNYI-PNYAARALVQN---RTQVVKLlil----eem 70
gi 15896789   2 STIKDVAKLSGVSPSTVSIILNGNAskrNISERTQRKVMDSVKKLNYH-PNIAARKLRSK---NSQSKPTialywssdis 77
gi 16124768     --------------------------------------------------------------------------------
gi 19704803   2 ITQKELAARLGVSRTTIARAINNSP---NIKPETKEKILKLVKELGYE-KNYVGSLLASK---KKIVYSFive----srn 70
gi 15829093   5 STYEEIAKKAKVSVSTVSRFYNNG----YVSEKNKNKINEIVLQHDLGvKHFTRINKKMN----NQIYFLihn----wtd 72
gi 15901650   9 VTIYDIARLSGFSPKTVSRVINGGVn---VKEETYQAIQKVIEELSYI-PNAYAKNLTKK---EAINILIsvk----kid 77
gi 15675250   6 ITIKDIAREAGVSVATVSYVLNQRNd-qKISEETRNKVLHISNLLNYT-PNQAARSLVTQ---QSNSVVLy--------- 71
gi 16122719   8 ATIVDIARRANVTNITVSRTFNQPG---LVKQETREKIHAIAKELNYV-PNAFAQGLKRS---SSQIIGIvts----smy 76
gi 16801298   2 ATLADVAKRANVSKMTVSRVINHPD---QVSDELKMLVYSAMEALEYV-PNYAARALVQN---RTQVIKFlil----eei 70
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1LBI_A       70 SlalHAPSQIVAAIKSRADQLGASVVVSMVERs--GVEACKTAVHNLLAQRVSGLIINYp-LDDQDAIAVEAACT--NVP 144
gi 3025303   71 DttePYYMNLLTGISRELDRNHYALQLVTRNSl-------------NIG-QCDGIIATG--LRKND-FEGVIKAF--EKP 131
gi 15896789  78 Vn---IISRFLRGLQSKLAKQNYNYNVVICPY---KTDCLHLEKGISKENSFDAAIIAN----ISNYDLEYLNKAslTLP 147
gi 16124768     --------------------------------------------------------------------------------
gi 19704803  71 SyytEQIKLGIKGAKKEYKHYNLEIIEIVTNInkpMEQVLKLKKLLNSDKQIDGIIIIP---LDKTKILELINPYleRIK 147
gi 15829093  73 N----DTLNIIAASNTFSNVHNKSIYITNCSAq--TQELISKMVEILIKKPYAIVLFFP---IVNDSLIDFINKLstETK 143
gi 15901650  78 SfplIWFHTLLDKVLRTCKEFGVNAIVEYFGE----EDTISNSIISSTGSLVDGVIVFY--ESVDDIRIQYLKKN--HMP 149
gi 15675250  72 ---yKYADSILARAEQLHTISFLSRLLHEQDY----QLVCLNEDSTEKFDWADLILTLD---VDNDTFYKIGKLN--FKP 139
gi 16122719  77 N---PFYSELIQTVSRIARTQCYQIMLFDTDG---SEEAEMEAIQALFGYKACGILLSPvrDDKNYQPAYLDLAEtyRVP 150
gi 16801298  71 DtvePYYMNLLTGISRELDKYYYSLQLVTQRSr-------------NIG-AYDGLIVTG--IRDKD-YELGLLDI--DKP 131
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1LBI_A      145 ALFLD---VsdQTPINSIIFSHEDGTRLGVEHLVALG--HQQIALLAGPLsSVSA-RLRLAGWHKYL--TRNQiqPIAER 216
gi 3025303  132 LVVFGqneMg----YDFIDVNNEKGTFMATRHVMGLG--EREVVFFGIDl-DEPFeRAREQGYIRAMnkSFKKsnMFRID 204
gi 15896789 148 IILFNrlsN----KYSSVNVDNYKMGEKASLLFAKKR--YKSAAAILTES-LNDAmDNRNKGFIETChkNGIKisENHII 220
gi 16124768     --------------------------------------------------------------------------------
gi 19704803 148 FITVSvflS---KKIAYVGTDYQKCGRLAAELLTKTLnsNDKVLVIDNGD-DNISsKYYLNGFLDRAnnDKMN----IVG 219
gi 15829093 144 IVIYGeknP----KVNSIFIDYKKMIYSLGNIFLERNn-KDKLALIIDSNlESKIsKQQIEGFISFCeqKQIS---CYLK 215
gi 15901650 150 FLVFGesqT---SGVVYVSNNNFQATYDMMKAVTEEK--FKNMWLLMGGE--SHVnKDRERGVRSFLndKNYFm-DLKVI 221
gi 15675250 140 LIAIDsfvN--DPLFFQINTDYAALKDQANQFFKD-----EPYTLLSLP----ITnRERYEHVS------------AFFP 196
gi 16122719 151 LILIDrdiYn--RQLSGVFLNNKEIGLLAGKYLSEQP--ERKMLIIGGPA-ESEItRVRIEGIINALenKKND---VHII 222
gi 16801298 132 VIFYGenkRg----YDSIDVDNKKGTALATEHVVEIG--FSRIVFLGIDLlDEQFmKSRLEGYEEVVrkHGLEpeSYFIA 205
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1LBI_A      217 EGDW-SAMSGFQQTMQMLNEGIV---PTAMLVANDQMALGAMRAITESGLR-VGA--DISVVGYDD-TEDSSCYIPPLTT 288
gi 3025303  205 NSSKkSECLARE----LL---KSmdnQAAFVCASDRIALGVIRAAQSLGKRiPED---VAVTGNDGv-FLDRISSPRLTT 273
gi 15896789 221 AAEN-SIHGGVDAAKKLMKLKNT---PKALFCNSDSIALGVISVLNKRQIS-IPDdiEIVAIGMND-REYTEFSTPPVTI 294
gi 16124768   1 -----MSRAVVDPSSKVSTRELN---LASCDSSGPFRAIAGSYCRFMVNSEtAPAp-DRGRLKMAD---IARMAGVSIST 68
gi 19704803 220 P----IKKNGVEESLQFLKTILKk--ENISSIFINRYAQDILLELSDNILKrQKN----ITTGIGNrIRKLIMERKILAT 289
gi 15829093 216 YFDNrNFDSIKKLVKNLKKLEVE-----NVISSTHDVFLNLLVHQPEFNFF-------ISDIGYQS---IFDYNKKYFVK 280
gi 15901650 222 YGLS-TIDSVYSYAMQHLTTQNY---PDIIFVSGDEKVQGLIRACYEKGIL-IPD--DISIIGFDN-IPISQYYTPALST 293
gi 15675250 197 ----------------------------SLHIVNDLRELTYFEKENLLLIDeSLD--QFFVNSSQK-LYCPRFSPKKGQV 245
gi 16122719 223 NGDY-DFISQEAAVRDYLSVPQNq--PDYIIGLNGILTLGAIAICHELKIY--NN---IKFFSIDE-PPKAADYGLHIAG 293
gi 16801298 206 NSSSvAEEKAFE----LL---RYnseKIAIVCASDRIAIGVVRAAAAFGRRfGEN---IAVTGFDGv-FLDRISSPKITT 274
                       330       340       350       360
                ....*....|....*....|....*....|....*....|....*...
1LBI_A      289 IKQDFRLLGQTSVDRLLQLSQ-GQAVKgNQ--LLPVSLVKRKTTLAPN 333
gi 3025303  274 VRQPVVEMGEACAKMLLKKMNeDG-AA-QGslFFEPELIVRESTL--- 316
gi 15896789 295 VDIPIEEMAGTCISLVEKLIN-RDIEN-PTsiLFDGPLILRNS----- 335
gi 16124768  69 VSRDLPLIFSSTRS---------------------------------- 82
gi 19704803 290 VADDVYSTGYKACQLMVDMLY-KEFGKsVKkiILEPQILLMENLK--- 333
gi 15829093 281 VFIDYHLLVLELARLLNNEQD-------IFslEISPKILIGK------ 315
gi 15901650 294 IAPNYVKLAKEMIEGVLAIIK-GES---VTsvEVSPKFVRRQSF---- 333
gi 15675250 246 ILEAIEWAKKRQPDKKHNLLV--------------------------- 266
gi 16122719 294 VYHDTQMLGEIAAELLFNAIK--KP---HNdqAVRREFFTGSLLTH-- 334
gi 16801298 275 VRSPVVEMGEELAKMLLAKINdHG-KP-QGnlLFTPELLIRASTTGKE 320
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